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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12543 scientific papers returned from the database with the search filters currently being used below.

Unraveling the regulative development and molecular mechanisms of identical sea urchin twins

Authors:
Suzuki H, Yaguchi J, Tsuyuzaki K, Yaguchi S
Citation:
Nat Commun. 2025 Sep 5;16(1):8005. doi: 10.1038/s41467-025-63111-z. PMID: 40913033; PMCID: PMC12413439
Epub:
Not Epub
Abstract:
Since Hans Driesch’s pioneering work in 1891, it has been known that animal embryos can develop into complete individuals even...
Link:
https://www.nature.com/articles/s41467-025-63111-z
Delivery Method:
microinjection
Organism or Cell Type:
H. pulcherrimus, S. purpuratus, Strongylocentrotus intermedius, Temnopleurus reevesii (sea urchin)
Citation Extract:
Suzuki H, Yaguchi J, Tsuyuzaki K, Yaguchi S. Unraveling the regulative development and molecular mechanisms of identical sea urchin twins. Nat Commun. 2025 Sep 5;16(1):8005. doi: 10.1038/s41467-025-63111-z. PMID: 40913033; PMCID: PMC12413439.

The role of REST in regulating the BDNF/TrkB signalling pathway in nano-alumina induced cognitive dysfunction in zebrafish

Authors:
Zhang J, Wang S, Jin Z, Ma L, Wang Y, Zhang H, Nie J, Niu Q
Citation:
Ecotoxicol Environ Saf. 2025 Sep 4;303:118998. doi: 10.1016/j.ecoenv.2025.118998. Epub ahead of print. PMID: 40912099
Epub:
Not Epub
Abstract:
Synaptic plasticity is fundamental for cognitive development and brain function. Aluminium nanoparticles (AlNPs), widely used...
Link:
https://www.sciencedirect.com/science/article/pii/S0147651325013430
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Wang S, Jin Z, Ma L, Wang Y, Zhang H, Nie J, Niu Q. The role of REST in regulating the BDNF/TrkB signalling pathway in nano-alumina induced cognitive dysfunction in zebrafish. Ecotoxicol Environ Saf. 2025 Sep 4;303:118998. doi: 10.1016/j.ecoenv.2025.118998. Epub ahead of print. PMID: 40912099.

The deficiency of DIP2C leads to congenital heart defects in patients with 10p15.3 microdeletion syndrome

Authors:
Xia Y, Zhang M, Song R, Wu H, Deng J, Huang S, Yang Y
Citation:
Gene. 2025 Sep 5:149753. doi: 10.1016/j.gene.2025.149753. Epub ahead of print. PMID: 40915331
Epub:
Not Epub
Abstract:
Background: Recurrent 10p15.3 microdeletion syndrome is a rare multisystem disorder characterized by abnormal facial features,...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0378111925005426
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia Y, Zhang M, Song R, Wu H, Deng J, Huang S, Yang Y. The deficiency of DIP2C leads to congenital heart defects in patients with 10p15.3 microdeletion syndrome. Gene. 2025 Sep 5:149753. doi: 10.1016/j.gene.2025.149753. Epub ahead of print. PMID: 40915331.

Adhesion strength, cell packing density and cell surface buckling in pericellular matrix-mediated tissue cohesion

Authors:
Winklbauer R, Luu O, Barua D, Nagel M, Huang Y
Citation:
Development. 2025 Aug 15;152(16):dev204663. doi: 10.1242/dev.204663. Epub 2025 Aug 26. PMID: 40772725
Epub:
Not Epub
Abstract:
Pericellular matrix-mediated cell-cell adhesion in Xenopus gastrula tissues is characterized by a spectrum of narrow and wide...
Link:
https://journals.biologists.com/dev/article/152/16/dev204663/368975/Adhesion-strength-cell-packing-density-and-cell
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Winklbauer R, Luu O, Barua D, Nagel M, Huang Y. Adhesion strength, cell packing density and cell surface buckling in pericellular matrix-mediated tissue cohesion. Development. 2025 Aug 15;152(16):dev204663. doi: 10.1242/dev.204663. Epub 2025 Aug 26. PMID: 40772725.

Mechanistic origins of temperature scaling in the early embryonic cell cycle

Authors:
Rombouts J, Tavella F, Vandervelde A, Phong C, Ferrell JE Jr, Yang Q, Gelens L
Citation:
Nat Commun. 2025 Aug 28;16(1):8045. doi: 10.1038/s41467-025-62918-0. PMID: 40877323; PMCID: PMC12394406
Epub:
Not Epub
Abstract:
Temperature strongly influences physiological and ecological processes, particularly in ectotherms. While complex physiological...
Link:
https://www.nature.com/articles/s41467-025-62918-0
Organism or Cell Type:
Xenopus laevis egg extracts
Citation Extract:
Rombouts J, Tavella F, Vandervelde A, Phong C, Ferrell JE Jr, Yang Q, Gelens L. Mechanistic origins of temperature scaling in the early embryonic cell cycle. Nat Commun. 2025 Aug 28;16(1):8045. doi: 10.1038/s41467-025-62918-0. PMID: 40877323; PMCID: PMC12394406.

Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models

Authors:
Zhang H, Shen S, Qian Y, Zhang L, Pu J, Zhou X, Yang N, Wang W
Citation:
Int Dent J. 2025 Aug 27;75(6):103874. doi: 10.1016/j.identj.2025.103874. Epub ahead of print. PMID: 40876387
Epub:
Not Epub
Abstract:
Background: Craniofacial malformations, caused by dysregulated neural crest cell (NCC) differentiation, affect approximately...
Link:
https://www.sciencedirect.com/science/article/pii/S0020653925031600
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang H, Shen S, Qian Y, Zhang L, Pu J, Zhou X, Yang N, Wang W. Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models. Int Dent J. 2025 Aug 27;75(6):103874. doi: 10.1016/j.identj.2025.103874. Epub ahead of print. PMID: 40876387.

Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential

Authors:
Morizet D, Foucher I, Mignerey I, Alunni A, Bally-Cuif L
Citation:
Sci Adv. 2025 Aug 29;11(35):eadu3189. doi: 10.1126/sciadv.adu3189. Epub 2025 Aug 27. PMID: 40864701; PMCID: PMC12383255
Epub:
Not Epub
Abstract:
In the vertebrate brain, neural stem cell (NSC) quiescence is necessary for stemness maintenance. Using single-cell RNA...
Link:
https://www.science.org/doi/10.1126/sciadv.adu3189
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Morizet D, Foucher I, Mignerey I, Alunni A, Bally-Cuif L. Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential. Sci Adv. 2025 Aug 29;11(35):eadu3189. doi: 10.1126/sciadv.adu3189. Epub 2025 Aug 27. PMID: 40864701; PMCID: PMC12383255.

Determining the importance of the stringent response for methicillin-resistant Staphylococcus aureus virulence in vivo

Authors:
Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA, Corrigan RM
Citation:
J Infect Dis. 2025 Aug 8:jiaf421. doi: 10.1093/infdis/jiaf421. Epub ahead of print. PMID: 40795378
Epub:
Not Epub
Abstract:
The stringent response is a stress signalling pathway with links to bacterial virulence. This pathway is controlled by the...
Link:
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiaf421/8228549
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA, Corrigan RM. Determining the importance of the stringent response for methicillin-resistant Staphylococcus aureus virulence in vivo. J Infect Dis. 2025 Aug 8:jiaf421. doi: 10.1093/infdis/jiaf421. Epub ahead of print. PMID: 40795378.

Perfluorodecanoic Acid (PFDA) Disrupts Immune Regulation via the Toll-like Receptor Signaling Pathway in Zebrafish

Authors:
Wang J, Fang D, Magnuson JT, Xu B, Zheng C, Schlenk D, Tang L, Qiu W
Citation:
Environ Sci Technol. 2025 Sep 1. doi: 10.1021/acs.est.5c04320. Epub ahead of print. PMID: 40891081
Epub:
Not Epub
Abstract:
As there are a growing number of per- and polyfluoroalkyl substances (PFAS) alternative substitutes applied globally, it...
Link:
https://pubs.acs.org/doi/10.1021/acs.est.5c04320
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Fang D, Magnuson JT, Xu B, Zheng C, Schlenk D, Tang L, Qiu W. Perfluorodecanoic Acid (PFDA) Disrupts Immune Regulation via the Toll-like Receptor Signaling Pathway in Zebrafish. Environ Sci Technol. 2025 Sep 1. doi: 10.1021/acs.est.5c04320. Epub ahead of print. PMID: 40891081.

In Vivo Phage Display for the Identification of Muscle Homing Peptides to Improve the Delivery of Phosphorodiamidate Morpholino Oligomers for Duchenne Muscular Dystrophy Therapy

Authors:
Schneider AE, Winter CLT, Mei H, Jirka SMG, Tan X, Thompson EG, Ha K, Mitra A, Garcia S, Luimes M, Oliver R, Morgan KY, Guerlavais V, Aartsma-Rus A
Citation:
Nucleic Acid Ther. 2025 Aug 29. doi: 10.1177/21593337251371708. Epub ahead of print. PMID: 40879532
Epub:
Not Epub
Abstract:
The severe X-linked degenerative neuromuscular disease Duchenne muscular dystrophy (DMD) is caused by the loss of dystrophin...
Link:
https://www.liebertpub.com/doi/10.1177/21593337251371708
Delivery Method:
peptide-linked
Organism or Cell Type:
mdx mice
Citation Extract:
Schneider AE, Winter CLT, Mei H, Jirka SMG, Tan X, Thompson EG, Ha K, Mitra A, Garcia S, Luimes M, Oliver R, Morgan KY, Guerlavais V, Aartsma-Rus A. In Vivo Phage Display for the Identification of Muscle Homing Peptides to Improve the Delivery of Phosphorodiamidate Morpholino Oligomers for Duchenne Muscular Dystrophy Therapy. Nucleic Acid Ther. 2025 Aug 29. doi: 10.1177/21593337251371708. Epub ahead of print. PMID: 40879532.

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