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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Microglia Mitigate Neuronal Activation in a Zebrafish Model of Dravet Syndrome.
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Citation:
Cells. 2024; 13(8):684. doi.org/10.3390/cells13080684 Epub:
Not Epub Abstract:
It has been known for a long time that epileptic seizures provoke brain neuroinflammation involving the activation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brenet A, Somkhit J, Csaba Z, Ciura S, Kabashi E, Yanicostas C, Soussi-Yanicostas N.. Microglia Mitigate Neuronal Activation in a Zebrafish Model of Dravet Syndrome.. Cells. 2024; 13(8):684. doi.org/10.3390/cells13080684. |
Generalizable anchor aptamer strategy for loading nucleic acid therapeutics on exosomes.
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Citation:
EMBO Mol Med. 2024 Mar 6. doi: 10.1038/s44321-024-00049-7. Online ahead of print. Epub:
Not Epub Abstract:
Clinical deployment of oligonucleotides requires delivery technologies that improve stability, target tissue accumulation and... Delivery Method:
PMO loaded on exosomes Organism or Cell Type:
Mouse Citation Extract: Han G, Zhang Y, Zhong L, Wang B, Qiu S, Song J, Lin C, Zou F, Wu J, Yu H, Liang C, Wen K, Seow Y, Yin H.. Generalizable anchor aptamer strategy for loading nucleic acid therapeutics on exosomes.. EMBO Mol Med. 2024 Mar 6. doi: 10.1038/s44321-024-00049-7. Online ahead of print.. |
Synthesis and Biophysical Properties of Triazole-Incorporated PMOs (TzPMOs): A Convergent, Click Ligation Approach.
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Citation:
J Org Chem. 2024 Mar 1;89(5):2895-2903. doi: 10.1021/acs.joc.3c02242. Epub 2024 Feb 12. Epub:
Not Epub Abstract:
The synthesis of phosphorodiamidate morpholino oligonucleotides (PMOs) incorporating single or double triazole rings in the... Delivery Method:
triazole-incorporated PMOs Citation Extract: Banerjee A, Das A, Ghosh A, Gupta A, Sinha S.. Synthesis and Biophysical Properties of Triazole-Incorporated PMOs (TzPMOs): A Convergent, Click Ligation Approach.. J Org Chem. 2024 Mar 1;89(5):2895-2903. doi: 10.1021/acs.joc.3c02242. Epub 2024 Feb 12.. |
Endothelial Cell Flow-Mediated Quiescence Is Temporally Regulated and Utilizes the Cell Cycle Inhibitor p27
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Citation:
Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1265-1282. doi: 10.1161/ATVBAHA.124.320671. Epub 2024 Apr 11. PMID: 38602102. Epub:
Not Epub Abstract:
Endothelial cells regulate their cell cycle as blood vessels remodel and transition to quiescence downstream of blood flow-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tanke NT, Liu Z, Gore MT, Bougaran P, Linares MB, Marvin A, Sharma A, Oatley M, Yu T, Quigley K, Vest S, Cook JG, Bautch VL.. Endothelial Cell Flow-Mediated Quiescence Is Temporally Regulated and Utilizes the Cell Cycle Inhibitor p27. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1265-1282. doi: 10.1161/ATVBAHA.124.320671. Epub 2024 Apr 11. PMID: 38602102.. |
METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway.
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Citation:
Cell Death Dis. 2024 Mar 20;15(3):229. doi: 10.1038/s41419-024-06606-9. Epub:
Not Epub Abstract:
Craniofacial malformations, often associated with syndromes, are prevalent birth defects. Emerging evidence underscores the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma L, Zhou X, Yao S, Zhang X, Mao J, Vona B, Fan L, Lou S, Li D, Wang L, Pan Y.. METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway.. Cell Death Dis. 2024 Mar 20;15(3):229. doi: 10.1038/s41419-024-06606-9.. |
Differentiation and functioning of the lateral line organ in zebrafish require Smpx activity
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Citation:
Sci Rep. 2024 Apr 3;14(1):7862. doi: 10.1038/s41598-024-58138-z Epub:
Not Epub Abstract:
The small muscle protein, X-linked (SMPX) gene encodes a cytoskeleton-associated protein, highly expressed in the inner ear... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Diana A, Ghilardi A, Del Giacco L. Differentiation and functioning of the lateral line organ in zebrafish require Smpx activity. Sci Rep. 2024 Apr 3;14(1):7862. doi: 10.1038/s41598-024-58138-z. |
The transcription of the main gene associated with Treacher-Collins syndrome (TCOF1) is regulated by G-quadruplexes and cellular nucleic acid binding protein (CNBP)
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Citation:
Sci Rep. 2024 Mar 29;14(1):7472. doi: 10.1038/s41598-024-58255-9 Epub:
Not Epub Abstract:
Treacle ribosome biogenesis factor 1 (TCOF1) is responsible for about 80% of mandibular dysostosis (MD) cases. We have formerly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gil Rosas M, Centola C, Torres M, Mouguelar VS, David AP, Piga EJ, Gomez D, Calcaterra NB, Armas P, Coux G. The transcription of the main gene associated with Treacher-Collins syndrome (TCOF1) is regulated by G-quadruplexes and cellular nucleic acid binding protein (CNBP). Sci Rep. 2024 Mar 29;14(1):7472. doi: 10.1038/s41598-024-58255-9. |
Establishment of a zebrafish inbred strain, M-AB, capable of regular breeding and genetic manipulation
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Citation:
Sci Rep. 2024 Mar 29;14(1):7455. doi: 10.1038/s41598-024-57699-3 Epub:
Not Epub Abstract:
Inbred strains of organisms are genetically highly uniform and thus useful for life science research. We have previously... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sadamitsu K, Velilla F, Shinya M, Kashima M, Imai Y, Kawasaki T, Watai K, Hosaka M, Hirata H, Sakai N. Establishment of a zebrafish inbred strain, M-AB, capable of regular breeding and genetic manipulation. Sci Rep. 2024 Mar 29;14(1):7455. doi: 10.1038/s41598-024-57699-3. |
MFSD12 depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis
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Citation:
Am J Physiol Renal Physiol. 2024 Jun 1;326(6):F981-F987. doi: 10.1152/ajprenal.00014.2024. Epub 2024 Mar 28. PMID: 38545650 Epub:
Not Epub Abstract:
In this study, we show that MFSD12 depletion with either CRISPR/Cas9-mediated gene editing or a translation-blocking morpholino... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bondue T, Khodaparast L, Khodaparast L, Cairoli S, Goffredo BM, Gijsbers R, van den Heuvel L, Levtchenko E. MFSD12 depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis. Am J Physiol Renal Physiol. 2024 Jun 1;326(6):F981-F987. doi: 10.1152/ajprenal.00014.2024. Epub 2024 Mar 28. PMID: 38545650. |
Forward genetic screen using a gene-breaking trap approach identifies a novel role of grin2bb-associated RNA transcript (grin2bbART) in zebrafish heart function
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Citation:
Front Cell Dev Biol. 2024 Mar 8;12:1339292. doi: 10.3389/fcell.2024.1339292. eCollection 2024. Epub:
Not Epub Abstract:
LncRNA-based control affects cardiac pathophysiologies like myocardial infarction, coronary artery disease, hypertrophy, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Angom RS, Joshi A, Patowary A, Sivadas A, Ramasamy S, K V S, Kaushik K, Sabharwal A, Lalwani MK, K S, Singh N, Scaria V, Sivasubbu S. Forward genetic screen using a gene-breaking trap approach identifies a novel role of grin2bb-associated RNA transcript (grin2bbART) in zebrafish heart function. Front Cell Dev Biol. 2024 Mar 8;12:1339292. doi: 10.3389/fcell.2024.1339292. eCollection 2024.. |