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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12326 scientific papers returned from the database with the search filters currently being used below.

Comprehensive analysis of the xbp1 gene in Pacific abalone Haliotis discus hannai: Structure, expression, and role in heat stress response

Authors:
Huang D, Li X, Pan M, Liu Y, Qin G, Chen Z, Yu X, Mai K, Zhang W
Citation:
Int J Biol Macromol. 2025 Jan 10:139771. doi: 10.1016/j.ijbiomac.2025.139771. Epub ahead of print. PMID: 39800022
Epub:
Not Epub
Abstract:
The present study explores the x-box binding protein 1 (xbp1) gene in Haliotis discus hannai (Pacific abalone), focusing on its...
Delivery Method:
injection
Organism or Cell Type:
Haliotis discus hannai (Pacific abalone)
Citation Extract:
Huang D, Li X, Pan M, Liu Y, Qin G, Chen Z, Yu X, Mai K, Zhang W. Comprehensive analysis of the xbp1 gene in Pacific abalone Haliotis discus hannai: Structure, expression, and role in heat stress response. Int J Biol Macromol. 2025 Jan 10:139771. doi: 10.1016/j.ijbiomac.2025.139771. Epub ahead of print. PMID: 39800022.

Loss-of-Function of CLMP Is Associated With Congenital Short Bowel Syndrome and Impaired Intestinal Development

Authors:
Chen S, Xu J, Xiao Y, Cai H, Zhou J, Cai W, Wang Y
Citation:
Clin Genet. 2025 Jan 6. doi: 10.1111/cge.14678. Epub ahead of print. PMID: 39763071
Epub:
Not Epub
Abstract:
Coxsackie and adenovirus receptor-like membrane protein (CLMP) mutation is identified as a genetic risk factor of congenital...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen S, Xu J, Xiao Y, Cai H, Zhou J, Cai W, Wang Y. Loss-of-Function of CLMP Is Associated With Congenital Short Bowel Syndrome and Impaired Intestinal Development. Clin Genet. 2025 Jan 6. doi: 10.1111/cge.14678. Epub ahead of print. PMID: 39763071.

CIROZ is dispensable in ancestral vertebrates but essential for left-right patterning in humans

Authors:
Szenker-Ravi E, Ott T, Yusof A, Chopra M, Khatoo M, Pak B, Xuan Goh W, Beckers A, Brady AF, Ewans LJ, Djaziri N, Almontashiri NAM, Alghamdi MA, Alharby E, Dasouki M, Romo L, Tan WH, Maddirevula S, Alkuraya FS, Giordano JL, Alkelai A, Wapner RJ, Stals K, Alfadhel M, Alswaid AF, Bogusch S, Schafer-Kosulya A, Vogel S, Vick P, Schweickert A, Wakeling M, Moreau de Bellaing A, Alshamsi AM, Sanlaville D, Mbarek H, Saad C, Ellard S, Eisenhaber F, Tripolszki K, Beetz C, Bauer P, Gossler A, Eisenhaber B, Blum M, Bouvagnet P, Bertoli-Avella A, Amiel J, Gordon CT, Reversade B
Citation:
Am J Hum Genet. 2024 Dec 27:S0002-9297(24)00448-8. doi: 10.1016/j.ajhg.2024.12.006. Epub ahead of print. PMID: 39753129
Epub:
Not Epub
Abstract:
Four genes-DAND5, PKD1L1, MMP21, and CIROP-form a genetic module that has specifically evolved in vertebrate species that...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Szenker-Ravi E, Ott T, Yusof A, Chopra M, Khatoo M, Pak B, Xuan Goh W, Beckers A, Brady AF, Ewans LJ, Djaziri N, Almontashiri NAM, Alghamdi MA, Alharby E, Dasouki M, Romo L, Tan WH, Maddirevula S, Alkuraya FS, Giordano JL, Alkelai A, Wapner RJ, Stals K, Alfadhel M, Alswaid AF, Bogusch S, Schafer-Kosulya A, Vogel S, Vick P, Schweickert A, Wakeling M, Moreau de Bellaing A, Alshamsi AM, Sanlaville D, Mbarek H, Saad C, Ellard S, Eisenhaber F, Tripolszki K, Beetz C, Bauer P, Gossler A, Eisenhaber B, Blum M, Bouvagnet P, Bertoli-Avella A, Amiel J, Gordon CT, Reversade B. CIROZ is dispensable in ancestral vertebrates but essential for left-right patterning in humans. Am J Hum Genet. 2024 Dec 27:S0002-9297(24)00448-8. doi: 10.1016/j.ajhg.2024.12.006. Epub ahead of print. PMID: 39753129.

Light intensity-dependent arrestin switching for inactivation of a light-sensitive GPCR, bistable opsin

Authors:
Shen B, Wada S, Sugihara T, Nagata T, Nishioka H, Kawano-Yamashita E, Ozawa T, Koyanagi M, Terakita A
Citation:
iSCIENCE (2025)
Epub:
Not Epub
Abstract:
Inactivation of most light-sensitive GPCR opsins involves arrestin binding to terminate cell responses. In the zebrafish pineal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shen B, Wada S, Sugihara T, Nagata T, Nishioka H, Kawano-Yamashita E, Ozawa T, Koyanagi M, Terakita A. Light intensity-dependent arrestin switching for inactivation of a light-sensitive GPCR, bistable opsin. iSCIENCE (2025).

Schwann cells have a limited window of time in which to initiate myelination signaling during early migration in vivo

Authors:
El-Hage O, Mikdache A, Boueid MJ, Degerny C, Tawk M
Citation:
Cells Dev. 2025 Jan 2:203993. doi: 10.1016/j.cdev.2024.203993. Epub ahead of print. PMID: 39755275
Epub:
Not Epub
Abstract:
The temporal control of mitotic exit of individual Schwann cells (SCs) is essential for radial sorting and peripheral...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
El-Hage O, Mikdache A, Boueid MJ, Degerny C, Tawk M. Schwann cells have a limited window of time in which to initiate myelination signaling during early migration in vivo. Cells Dev. 2025 Jan 2:203993. doi: 10.1016/j.cdev.2024.203993. Epub ahead of print. PMID: 39755275.

Infiltrating macrophages and interferon gamma rather than renal genotype dictate heightened crescentic glomerulonephritis

Authors:
Du Y, Fu Y, Gao Y, Poojitha D, Kamala V, Li Q, Zhou X, Mohan C
Citation:
Front Immunol. 2024 Dec 19;15:1484525. doi: 10.3389/fimmu.2024.1484525. PMID: 39749339; PMCID: PMC11693704
Epub:
Not Epub
Abstract:
Background: Both intrinsic renal cells and immune cells contribute to driving renal inflammation and damage. However, the...
Delivery Method:
Endo-Porter
Organism or Cell Type:
129x1/svJ bone marrow-derived macrophages
Citation Extract:
Du Y, Fu Y, Gao Y, Poojitha D, Kamala V, Li Q, Zhou X, Mohan C. Infiltrating macrophages and interferon gamma rather than renal genotype dictate heightened crescentic glomerulonephritis. Front Immunol. 2024 Dec 19;15:1484525. doi: 10.3389/fimmu.2024.1484525. PMID: 39749339; PMCID: PMC11693704.

Her9 controls the stemness properties of hindbrain boundary cells

Authors:
Engel-Pizcueta C, Hevia CF, Voltes A, Livet J, Pujades C
Citation:
Development. 2025 Jan 1;152(1):dev203164. doi: 10.1242/dev.203164. Epub 2025 Jan 2. PMID: 39628452
Epub:
Not Epub
Abstract:
The different spatiotemporal distribution of progenitor and neurogenic capacities permits that brain regions engage...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Engel-Pizcueta C, Hevia CF, Voltes A, Livet J, Pujades C. Her9 controls the stemness properties of hindbrain boundary cells. Development. 2025 Jan 1;152(1):dev203164. doi: 10.1242/dev.203164. Epub 2025 Jan 2. PMID: 39628452.

Role of LSM34/SpSM50 Proteins in Endoskeletal Spicule Formation in Sea Urchin Embryos

Authors:
Wilt, F., Croker, L., Killian, C. E., & McDonald, K.
Citation:
Invertebrate Biology, 127(4), 452–459, (31 December 2024). https://doi.org/10.1111/j.1744-7410.2008.00147.x
Epub:
Not Epub
Abstract:
Sea urchin embryos form an endoskeletal spicule composed of calcium carbonate and occluded matrix proteins. The accumulation of...
Delivery Method:
microinjection
Organism or Cell Type:
Lytechinus pictus and Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Wilt, F., Croker, L., Killian, C. E., & McDonald, K.. Role of LSM34/SpSM50 Proteins in Endoskeletal Spicule Formation in Sea Urchin Embryos. Invertebrate Biology, 127(4), 452–459, (31 December 2024). https://doi.org/10.1111/j.1744-7410.2008.00147.x.

PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression

Authors:
Haas M, Cherfa S, Nguyen L, Bourgoin M, Caron G, Dessauge E, Marchand T, Delpy L, Auberger P, Moreaux J, Jacquel A, Fest T
Citation:
Nat Commun. 2025 Jan 2;16(1):256. doi: 10.1038/s41467-024-55572-5. PMID: 39747141; PMCID: PMC11696207
Epub:
Not Epub
Abstract:
Our study explores the complex dynamics of the integrated stress response (ISR) axis, highlighting PIM2 kinase's critical...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Human peripheral blood primary B cells; multiple myeloma cell lines engrafted into NSG mice
Citation Extract:
Haas M, Cherfa S, Nguyen L, Bourgoin M, Caron G, Dessauge E, Marchand T, Delpy L, Auberger P, Moreaux J, Jacquel A, Fest T. PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression. Nat Commun. 2025 Jan 2;16(1):256. doi: 10.1038/s41467-024-55572-5. PMID: 39747141; PMCID: PMC11696207.

NaP-TRAP reveals the regulatory grammar in 5'UTR-mediated translation regulation during zebrafish development

Authors:
Strayer EC, Krishna S, Lee H, Vejnar C, Neuenkirchen N, Gupta A, Beaudoin JD, Giraldez AJ
Citation:
Nat Commun. 2024 Dec 30;15(1):10898. doi: 10.1038/s41467-024-55274-y. PMID: 39738051; PMCID: PMC11685710
Epub:
Not Epub
Abstract:
The cis-regulatory elements encoded in an mRNA determine its stability and translational output. While there has been a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Strayer EC, Krishna S, Lee H, Vejnar C, Neuenkirchen N, Gupta A, Beaudoin JD, Giraldez AJ. NaP-TRAP reveals the regulatory grammar in 5'UTR-mediated translation regulation during zebrafish development. Nat Commun. 2024 Dec 30;15(1):10898. doi: 10.1038/s41467-024-55274-y. PMID: 39738051; PMCID: PMC11685710.

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