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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11661 scientific papers returned from the database with the search filters currently being used below.

gldc Is Essential for Renal Progenitor Patterning during Kidney Development

Authors:
Weaver NE, Healy A, Wingert RA
Citation:
Biomedicines. 2022;10(12):3220. doi:10.3390/biomedicines10123220
Epub:
Not Epub
Abstract:
The glycine cleavage system (GCS) is a complex located on the mitochondrial membrane that is responsible for regulating glycine...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weaver NE, Healy A, Wingert RA. gldc Is Essential for Renal Progenitor Patterning during Kidney Development. Biomedicines. 2022;10(12):3220. doi:10.3390/biomedicines10123220.

GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development

Authors:
Lo Y-H, Huang Y-S, Chang Y-C, Hung P-Y, Wang W-D, Liu W, Urade R, Wen Z-H, Wu C-Y
Citation:
Biomedicines. 2022;10(12):3208. doi:10.3390/biomedicines10123208
Epub:
Not Epub
Abstract:
Genetic regulation of vascular patterning is not fully understood. Here, we report a novel gene, gtpbp1l (GTP-binding protein 1...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lo Y-H, Huang Y-S, Chang Y-C, Hung P-Y, Wang W-D, Liu W, Urade R, Wen Z-H, Wu C-Y. GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development. Biomedicines. 2022;10(12):3208. doi:10.3390/biomedicines10123208.

Disruption of fos causes craniofacial anomalies in developing zebrafish

Authors:
Maili L, Tandon B, Yuan Q, Menezes S, Hashmi SS, Letra A, Eisenhoffer GT, Hecht JT
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.12.06.519379
Epub:
Not Epub
Abstract:
Craniofacial development is a complex and tightly regulated process and disruptions can lead to structural birth defects, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maili L, Tandon B, Yuan Q, Menezes S, Hashmi SS, Letra A, Eisenhoffer GT, Hecht JT. Disruption of fos causes craniofacial anomalies in developing zebrafish. bioRxiv. 2022;[preprint] doi:10.1101/2022.12.06.519379.

Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development

Authors:
Xiao Y, Chen J, Yang S, Sun H, Xie L, Li J, Jing N, Zhu X
Citation:
EMBO J. 2022 Dec 7:e111364. doi: 10.15252/embj.2022111364. Online ahead of print
Epub:
Yes
Abstract:
Early embryonic development depends on proper utilization and clearance of maternal transcriptomes. How these processes are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiao Y, Chen J, Yang S, Sun H, Xie L, Li J, Jing N, Zhu X. Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development. EMBO J. 2022 Dec 7:e111364. doi: 10.15252/embj.2022111364. Online ahead of print.

Chemokine signaling synchronizes angioblast proliferation and differentiation during pharyngeal arch artery vasculogenesis

Authors:
Liu J, Zhang M, Dong H, Liu J, Mao A, Ning G, Cao Y, Zhang Y, Wang Q
Citation:
Development. 2022 Dec 1;149(23):dev200754. doi: 10.1242/dev.200754. Epub 2022 Dec 5. PMID: 36468454
Epub:
Not Epub
Abstract:
Developmentally, the great vessels of the heart originate from the pharyngeal arch arteries (PAAs). During PAA vasculogenesis,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J, Zhang M, Dong H, Liu J, Mao A, Ning G, Cao Y, Zhang Y, Wang Q. Chemokine signaling synchronizes angioblast proliferation and differentiation during pharyngeal arch artery vasculogenesis. Development. 2022 Dec 1;149(23):dev200754. doi: 10.1242/dev.200754. Epub 2022 Dec 5. PMID: 36468454.

Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling

Authors:
Zhao C, Matalonga J, Lancman JJ, Liu L, Xiao C, Kumar S, Gates KP, He J, Graves A, Huisken J, Azuma M, Lu Z, Chen C, Ding BS, Dong PDS
Citation:
Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2201097119. doi: 10.1073/pnas.2201097119. Epub 2022 Dec 5
Epub:
Not Epub
Abstract:
Despite the robust healing capacity of the liver, regenerative failure underlies numerous hepatic diseases, including the JAG1...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao C, Matalonga J, Lancman JJ, Liu L, Xiao C, Kumar S, Gates KP, He J, Graves A, Huisken J, Azuma M, Lu Z, Chen C, Ding BS, Dong PDS. Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2201097119. doi: 10.1073/pnas.2201097119. Epub 2022 Dec 5.

A Missense Variant in PDK1 Associated with Severe Neurodevelopmental Delay and Epilepsy

Authors:
Vaz R, Wincent J, Elfissi N, Rosengren Forsblad K, Pettersson M, Naess K, Wedell A, Wredenberg A, Lindstrand A, Ygberg S
Citation:
Biomedicines. 2022;10(12):3171. doi:10.3390/biomedicines10123171
Epub:
Not Epub
Abstract:
The pyruvate dehydrogenase complex (PDC) is responsible for the conversion of pyruvate into acetyl-CoA, which is used for...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vaz R, Wincent J, Elfissi N, Rosengren Forsblad K, Pettersson M, Naess K, Wedell A, Wredenberg A, Lindstrand A, Ygberg S. A Missense Variant in PDK1 Associated with Severe Neurodevelopmental Delay and Epilepsy. Biomedicines. 2022;10(12):3171. doi:10.3390/biomedicines10123171 .

CD14+/CD31+ Monocytes Expanded by UM171 Correct Hemophilia A in Zebrafish upon Lentiviral Gene Transfer of Factor VIII

Authors:
Elnaggar M, Al-Mohannadi A, Hasan W, Abdelrahman D, Al-Kubaisi MJ, Pavlovski I, Gentlcore G, Sathappan A, Kizhakayil D, Ali AI, Mohan S, Olagunju D, Cugno C, Grivel JC, Borsotti C, Follenzi A, Da'as S, Deola S
Citation:
Blood Adv. 2022 Dec 7:bloodadvances.2022009014. doi: 10.1182/bloodadvances.2022009014. Online ahead of print
Epub:
Not Epub
Abstract:
Emerging gene therapy (GT) clinical trials test the correction of hemophilia A (HA) by replacing factor VIII (FVIII) in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elnaggar M, Al-Mohannadi A, Hasan W, Abdelrahman D, Al-Kubaisi MJ, Pavlovski I, Gentlcore G, Sathappan A, Kizhakayil D, Ali AI, Mohan S, Olagunju D, Cugno C, Grivel JC, Borsotti C, Follenzi A, Da'as S, Deola S. CD14+/CD31+ Monocytes Expanded by UM171 Correct Hemophilia A in Zebrafish upon Lentiviral Gene Transfer of Factor VIII. Blood Adv. 2022 Dec 7:bloodadvances.2022009014. doi: 10.1182/bloodadvances.2022009014. Online ahead of print.

Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration

Authors:
Mitra S, Devi S, Lee M-S, Goldman D
Citation:
Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2211690119. doi: 10.1073/pnas.2211690119. Epub 2022 Dec 5
Epub:
Not Epub
Abstract:
In the zebrafish retina, Müller glia (MG) can regenerate retinal neurons lost to injury or disease. Even though zebrafish MG...
Delivery Method:
injection
Organism or Cell Type:
zebrafish
Citation Extract:
Mitra S, Devi S, Lee M-S, Goldman D. Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2211690119. doi: 10.1073/pnas.2211690119. Epub 2022 Dec 5.

Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption

Authors:
Vit G, Hirth A, Neugebauer N, Kraft BN, Sigismondo G, Cazzola A, Tessmer C, Duro J, Krijgsveld J, Hofmann I, Berger M, Klüter H, Niehrs C, Nilsson J, Krämer A
Citation:
Cell Death Discov. 2022;8(1):484. doi:10.1038/s41420-022-01274-0
Epub:
Not Epub
Abstract:
The Schlafen gene family was first described in mice as a regulator of thymocyte development. Further studies showed...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vit G, Hirth A, Neugebauer N, Kraft BN, Sigismondo G, Cazzola A, Tessmer C, Duro J, Krijgsveld J, Hofmann I, Berger M, Klüter H, Niehrs C, Nilsson J, Krämer A. Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption. Cell Death Discov. 2022;8(1):484. doi:10.1038/s41420-022-01274-0.

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