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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12282 scientific papers returned from the database with the search filters currently being used below.

Role of ZFHX4 in orofacial clefting based on human genetic data and zebrafish models

Authors:
Ishorst N, Hölzel S, Greve C, Yilmaz Ö, Lindenberg T, Lambertz J, Drichel D, Zametica B, Mingardo E, Kalanithy JC, Channab K, Kibris D, Henne S, Degenhardt F, Siewert A, Dixon M, Kruse T, Ongkosuwito E, Girisha KM, Pande S, Nowak S, Hagelueken G, Geyer M, Carels C, van Rooij IALM, Ludwig KU, Odermatt B, Mangold E
Citation:
Eur J Hum Genet. 2024 Dec 19. doi: 10.1038/s41431-024-01775-9. Epub ahead of print. PMID: 39702590
Epub:
Not Epub
Abstract:
Orofacial clefting (OFC) is a frequent congenital anomaly and can occur either in the context of underlying syndromes or in...
Link:
https://www.nature.com/articles/s41431-024-01775-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ishorst N, Hölzel S, Greve C, Yilmaz Ö, Lindenberg T, Lambertz J, Drichel D, Zametica B, Mingardo E, Kalanithy JC, Channab K, Kibris D, Henne S, Degenhardt F, Siewert A, Dixon M, Kruse T, Ongkosuwito E, Girisha KM, Pande S, Nowak S, Hagelueken G, Geyer M, Carels C, van Rooij IALM, Ludwig KU, Odermatt B, Mangold E. Role of ZFHX4 in orofacial clefting based on human genetic data and zebrafish models. Eur J Hum Genet. 2024 Dec 19. doi: 10.1038/s41431-024-01775-9. Epub ahead of print. PMID: 39702590.

Generation and characterization of zebrafish f9l mutant confirmed that f9l is f10 like gene

Authors:
Dhinoja S, Mary J, Qaryoute AA, De Maria A, Jagadeeswaran P
Citation:
Blood Coagul Fibrinolysis. 2024 Dec 2. doi: 10.1097/MBC.0000000000001337. Epub ahead of print. PMID: 39661534
Epub:
Not Epub
Abstract:
Aim: This study aimed to create an f9l mutant zebrafish using clustered regularly interspaced short palindromic repeats (CRISPR...
Link:
https://journals.lww.com/bloodcoagulation/abstract/9900/generation_and_characterization_of_zebrafish_f9l.178.aspx
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dhinoja S, Mary J, Qaryoute AA, De Maria A, Jagadeeswaran P. Generation and characterization of zebrafish f9l mutant confirmed that f9l is f10 like gene. Blood Coagul Fibrinolysis. 2024 Dec 2. doi: 10.1097/MBC.0000000000001337. Epub ahead of print. PMID: 39661534.

Perfluorohexanesulfonic Acid (PFHxS) Induces Hepatotoxicity through the PPAR Signaling Pathway in Larval Zebrafish (Danio rerio)

Authors:
Liao H, He YJ, Zhang S, Kang X, Yang X, Xu B, Magnuson JT, Wang S, Zheng C, Qiu W
Citation:
Environ Sci Technol. 2024 Dec 16. doi: 10.1021/acs.est.4c07056. Epub ahead of print. PMID: 39680074
Epub:
Not Epub
Abstract:
In recent years, the industrial substitution of long-chain per- and polyfluoroalkyl substances (PFAS) with short-chain...
Link:
https://pubs.acs.org/doi/10.1021/acs.est.4c07056
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liao H, He YJ, Zhang S, Kang X, Yang X, Xu B, Magnuson JT, Wang S, Zheng C, Qiu W. Perfluorohexanesulfonic Acid (PFHxS) Induces Hepatotoxicity through the PPAR Signaling Pathway in Larval Zebrafish (Danio rerio). Environ Sci Technol. 2024 Dec 16. doi: 10.1021/acs.est.4c07056. Epub ahead of print. PMID: 39680074.

A Novel De Novo Missense Variant in Netrin-1 (NTN1) Associated With Chorioretinal Coloboma, Sensorineural Hearing Loss and Polydactyly

Authors:
Toms M, Heppell C, Owen N, Malka S, Moosajee M; Genomics England Research Consortium
Citation:
Clin Genet. 2024 Dec 8. doi: 10.1111/cge.14651. Epub ahead of print. PMID: 39648562
Epub:
Not Epub
Abstract:
Microphthalmia, anophthalmia and coloboma (MAC) comprise a highly heterogeneous spectrum of congenital ocular malformations...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/cge.14651
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toms M, Heppell C, Owen N, Malka S, Moosajee M; Genomics England Research Consortium. A Novel De Novo Missense Variant in Netrin-1 (NTN1) Associated With Chorioretinal Coloboma, Sensorineural Hearing Loss and Polydactyly. Clin Genet. 2024 Dec 8. doi: 10.1111/cge.14651. Epub ahead of print. PMID: 39648562.

Follistatin like-1 (Fstl1) regulates adipose tissue development in zebrafish

Authors:
Guggeri L, Sosa-Redaelli I, Cárdenas-Rodríguez M, Alonso M, González G, Naya H, Prieto-Echagüe V, Lepanto P, Badano JL
Citation:
Adipocyte. 2024 Dec;13(1):2435862. doi: 10.1080/21623945.2024.2435862. Epub 2024 Dec 7. PMID: 39644214; PMCID: PMC11633180
Epub:
Not Epub
Abstract:
Obesity is a highly prevalent disorder with complex aetiology. Therefore, studying its associated cellular and molecular...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11633180/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guggeri L, Sosa-Redaelli I, Cárdenas-Rodríguez M, Alonso M, González G, Naya H, Prieto-Echagüe V, Lepanto P, Badano JL. Follistatin like-1 (Fstl1) regulates adipose tissue development in zebrafish. Adipocyte. 2024 Dec;13(1):2435862. doi: 10.1080/21623945.2024.2435862. Epub 2024 Dec 7. PMID: 39644214; PMCID: PMC11633180.

Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma

Authors:
Chakraborty S, Sarma J, Roy SS, Mitra S, Bagchi S, Das S, Saha S, Mahapatra S, Bhattacharjee S, Maulik M, Acharya M
Citation:
PLoS Genet. 2024 Dec 5;20(12):e1011502. doi: 10.1371/journal.pgen.1011502. PMID: 39637236; PMCID: PMC11651621
Epub:
Not Epub
Abstract:
Primary angle closure glaucoma (PACG) affects more than 20 million people worldwide, with an increased prevalence in south-east...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11651621/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chakraborty S, Sarma J, Roy SS, Mitra S, Bagchi S, Das S, Saha S, Mahapatra S, Bhattacharjee S, Maulik M, Acharya M. Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma. PLoS Genet. 2024 Dec 5;20(12):e1011502. doi: 10.1371/journal.pgen.1011502. PMID: 39637236; PMCID: PMC11651621.

Development of a riboflavin-responsive model of riboflavin transporter deficiency in zebrafish

Authors:
Choueiri CM, Lau J, O'Connor E, DiBattista A, Wong BY, Spendiff S, Horvath R, Pena I, MacKenzie A, Lochmüller H
Citation:
Hum Mol Genet. 2024 Dec 4:ddae171. doi: 10.1093/hmg/ddae171. Epub ahead of print. PMID: 39656631
Epub:
Not Epub
Abstract:
Riboflavin transporter deficiency (RTD) is a rare and progressive neurodegenerative disease resulting from the disruption of...
Link:
https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddae171/7914590
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choueiri CM, Lau J, O'Connor E, DiBattista A, Wong BY, Spendiff S, Horvath R, Pena I, MacKenzie A, Lochmüller H. Development of a riboflavin-responsive model of riboflavin transporter deficiency in zebrafish. Hum Mol Genet. 2024 Dec 4:ddae171. doi: 10.1093/hmg/ddae171. Epub ahead of print. PMID: 39656631.

Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation

Authors:
Bowley G, Irving S, Hoefer I, Wilkinson R, Pasterkamp G, Darwish HMS, White S, Francis SE, Chico T, Noel E, Serbanovic-Canic J, Evans PC
Citation:
Sci Rep. 2024 Dec 3;14(1):30130. doi: 10.1038/s41598-024-77370-1. PMID: 39627337
Epub:
Not Epub
Abstract:
Local haemodynamics control arterial homeostasis and dysfunction by generating wall shear stress (WSS) which regulates...
Link:
https://www.nature.com/articles/s41598-024-77370-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bowley G, Irving S, Hoefer I, Wilkinson R, Pasterkamp G, Darwish HMS, White S, Francis SE, Chico T, Noel E, Serbanovic-Canic J, Evans PC. Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation. Sci Rep. 2024 Dec 3;14(1):30130. doi: 10.1038/s41598-024-77370-1. PMID: 39627337.

Tubulin glutamylation regulates axon guidance via the selective tuning of microtubule-severing enzymes

Authors:
Ten Martin D, Jardin N, Vougny J, Giudicelli F, Gasmi L, Berbée N, Henriot V, Lebrun L, Haumaître C, Kneussel M, Nicol X, Janke C, Magiera MM, Hazan J, Fassier C
Citation:
EMBO J. 2024 Nov 29. doi: 10.1038/s44318-024-00307-x. Epub ahead of print. PMID: 39613968
Epub:
Not Epub
Abstract:
The microtubule cytoskeleton is a major driving force of neuronal circuit development. Fine-tuned remodelling of this network...
Link:
https://www.embopress.org/doi/full/10.1038/s44318-024-00307-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ten Martin D, Jardin N, Vougny J, Giudicelli F, Gasmi L, Berbée N, Henriot V, Lebrun L, Haumaître C, Kneussel M, Nicol X, Janke C, Magiera MM, Hazan J, Fassier C. Tubulin glutamylation regulates axon guidance via the selective tuning of microtubule-severing enzymes. EMBO J. 2024 Nov 29. doi: 10.1038/s44318-024-00307-x. Epub ahead of print. PMID: 39613968.

Comparative molecular dynamics calculations of duplexation of chemically modified analogs of DNA used for antisense applications

Authors:
Galindo-Murillo R, Cohen JS, Akabayov B
Citation:
NAR Genomics and Bioinformatics. Volume 6, Issue 4. December 2024. lqae155. https://doi.org/10.1093/nargab/lqae155
Epub:
Not Epub
Abstract:
We have subjected several analogs of DNA that have been widely used as antisense oligonucleotide (ASO) inhibitors of gene...
Link:
https://academic.oup.com/nargab/article/6/4/lqae155/7912069
Delivery Method:
None
Organism or Cell Type:
None
Citation Extract:
Galindo-Murillo R, Cohen JS, Akabayov B. Comparative molecular dynamics calculations of duplexation of chemically modified analogs of DNA used for antisense applications. NAR Genomics and Bioinformatics. Volume 6, Issue 4. December 2024. lqae155. https://doi.org/10.1093/nargab/lqae155.

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