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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12515 scientific papers returned from the database with the search filters currently being used below.

Identification of novel NDUFA3 variants in a patient with mitochondrial disorders

Authors:
Sun Y, Wei X, Xiao B, Luo Y, Wang Y, Liu R, Zhan Y, Ye X, Cai X, Xu S, Lyu J, Fang H, Yu Y
Citation:
Pediatr Res. 2025 Oct 2. doi: 10.1038/s41390-025-04403-4. Epub ahead of print. PMID: 41038977
Epub:
Not Epub
Abstract:
Background: Mitochondrial respiratory chain (RC) dysfunction constitutes the biochemical defect underlining a group of...
Link:
https://www.nature.com/articles/s41390-025-04403-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Wei X, Xiao B, Luo Y, Wang Y, Liu R, Zhan Y, Ye X, Cai X, Xu S, Lyu J, Fang H, Yu Y. Identification of novel NDUFA3 variants in a patient with mitochondrial disorders. Pediatr Res. 2025 Oct 2. doi: 10.1038/s41390-025-04403-4. Epub ahead of print. PMID: 41038977.

DG9-Conjugated Morpholino-Based Exon 51-Skipping Therapy for Duchenne Muscular Dystrophy

Authors:
Shah MNA, Sutanto LE, Yokota T
Citation:
Methods Mol Biol. 2026;2963:1-14. doi: 10.1007/978-1-0716-4738-7_1. PMID: 41028673
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a severe genetic disorder caused by mutations in the DMD gene that leads to the loss of...
Link:
https://link.springer.com/protocol/10.1007/978-1-0716-4738-7_1
Delivery Method:
DG9 peptide-linked; retro-orbital
Organism or Cell Type:
mdx mice
Citation Extract:
Shah MNA, Sutanto LE, Yokota T. DG9-Conjugated Morpholino-Based Exon 51-Skipping Therapy for Duchenne Muscular Dystrophy. Methods Mol Biol. 2026;2963:1-14. doi: 10.1007/978-1-0716-4738-7_1. PMID: 41028673.

DG9-Conjugated Morpholino Rescues Phenotype in Spinal Muscular Atrophy Mice

Authors:
Haque US, Kohut M, Yokota T
Citation:
Methods Mol Biol. 2026;2963:15-40. doi: 10.1007/978-1-0716-4738-7_2. PMID: 41028674
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a progressive neurodegenerative disease characterized by decreased expression of the survival...
Link:
https://link.springer.com/protocol/10.1007/978-1-0716-4738-7_2
Delivery Method:
DG9 peptide-linked, subcutaneous (s.c.)
Organism or Cell Type:
SMA mice
Citation Extract:
Haque US, Kohut M, Yokota T. DG9-Conjugated Morpholino Rescues Phenotype in Spinal Muscular Atrophy Mice. Methods Mol Biol. 2026;2963:15-40. doi: 10.1007/978-1-0716-4738-7_2. PMID: 41028674.

A Live-Cell NanoBRET Assay to Monitor RNA–Protein Interactions and Their Inhibition by Small Molecules

Authors:
Shan J, Taghavi A, Caine EA, Sekioka R, Rajchin V, Burke JM, Watkins JM, Childs-Disney JL, Disney MD
Citation:
ACS Cent. Sci. 2025 Sep 25. doi: 10.1021/acscentsci.5c00705
Epub:
Not Epub
Abstract:
RNA–protein interactions are critical for cellular processes, including translation, pre-mRNA splicing, post-transcriptional...
Link:
https://pubs.acs.org/doi/10.1021/acscentsci.5c00705
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
HeLa480 cells
Citation Extract:
Shan J, Taghavi A, Caine EA, Sekioka R, Rajchin V, Burke JM, Watkins JM, Childs-Disney JL, Disney MD. A Live-Cell NanoBRET Assay to Monitor RNA–Protein Interactions and Their Inhibition by Small Molecules. ACS Cent. Sci. 2025 Sep 25. doi: 10.1021/acscentsci.5c00705.

Transcriptome Analysis of Zyxin Cytoskeletal Protein Levels: Influence on Metabolism and Signaling Pathways in a Model of Xenopus laevis Embryos

Authors:
Parshina EA, Zaraisky A, Martynova N
Citation:
Russ J Bioorg Chem 51, 1990–1999 (2025). https://doi.org/10.1134/S1068162025601983
Epub:
Not Epub
Abstract:
Objective: Zyxin is a cytoskeletal protein that plays a crucial role in the assembly and restoration of actin filaments....
Link:
https://link.springer.com/article/10.1134/S1068162025601983
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Parshina EA, Zaraisky A, Martynova N. Transcriptome Analysis of Zyxin Cytoskeletal Protein Levels: Influence on Metabolism and Signaling Pathways in a Model of Xenopus laevis Embryos. Russ J Bioorg Chem 51, 1990–1999 (2025). https://doi.org/10.1134/S1068162025601983.

Cytoskeletal Regulator Zyxin Stimulates Nuclear Translocation of YAP in Xenopus laevis Embryonic Cells

Authors:
Parshina EA, Orlov EE, Voronezhskaya EE, Martynova NY, Zaraisky AG
Citation:
Russ J Bioorg Chem 51, 1945–1953 (2025). https://doi.org/10.1134/S1068162025601727
Epub:
Not Epub
Abstract:
Objective: This study investigates the impact of zyxin on Yes-associated protein (YAP) signaling during embryonic development...
Link:
https://link.springer.com/article/10.1134/S1068162025601727
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Parshina EA, Orlov EE, Voronezhskaya EE, Martynova NY, Zaraisky AG. Cytoskeletal Regulator Zyxin Stimulates Nuclear Translocation of YAP in Xenopus laevis Embryonic Cells. Russ J Bioorg Chem 51, 1945–1953 (2025). https://doi.org/10.1134/S1068162025601727.

Importin α regulates ciliogenesis and cilia length with implications for Xenopus nephrogenesis

Authors:
Mosqueda N, Sutton PJ, Brownlee CW
Citation:
J Cell Sci. 2025 Sep 29:jcs.264441. doi: 10.1242/jcs.264441. Epub ahead of print. PMID: 41017282
Epub:
Not Epub
Abstract:
Cilia are microtubule-based organelles essential for a wide range of biological processes ranging from facilitating fluid flow...
Link:
https://journals.biologists.com/jcs/article-abstract/doi/10.1242/jcs.264441/369331/Importin-regulates-ciliogenesis-and-cilia-length
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mosqueda N, Sutton PJ, Brownlee CW. Importin α regulates ciliogenesis and cilia length with implications for Xenopus nephrogenesis. J Cell Sci. 2025 Sep 29:jcs.264441. doi: 10.1242/jcs.264441. Epub ahead of print. PMID: 41017282.

Integrative Multi-Omics Analysis In Vivo Identifies Influenza A Virus Host Factors

Authors:
Shriver LP, Polacco B, Eckhardt M, Chang MW, Martínez-Romero C, Adkins-Travis K, Cahalane C, Haas K, Stein DA, Fourati S, Martin-Sancho L, Metreveli G, Johnson JR, Muñoz-Moreno R, Newton BW, Kaake RM, Zhou Y, Jimenez-Morales D, VonDollen J, Verschueren E, Swaney DL, Nguyen TT, Stevenson EJ, Stancliffe E, Patti GJ, Albrecht R, Moulton HM, Pache L, Sekaly RP, Benner C, Hultquist JF, Chanda SK, Garcia Sastre A, Krogan NJ
Citation:
iScience. 22 September 2025
Epub:
Not Epub
Abstract:
Influenza A virus (IAV) infection remodels cellular processes to support viral replication. Modulation of host factors by the...
Link:
https://www.sciencedirect.com/science/article/pii/S2589004225019054
Delivery Method:
intranasal peptide-linked
Organism or Cell Type:
Balb/CJ mice; mouse embryonic fibroblasts (MEFs)
Citation Extract:
Shriver LP, Polacco B, Eckhardt M, Chang MW, Martínez-Romero C, Adkins-Travis K, Cahalane C, Haas K, Stein DA, Fourati S, Martin-Sancho L, Metreveli G, Johnson JR, Muñoz-Moreno R, Newton BW, Kaake RM, Zhou Y, Jimenez-Morales D, VonDollen J, Verschueren E, Swaney DL, Nguyen TT, Stevenson EJ, Stancliffe E, Patti GJ, Albrecht R, Moulton HM, Pache L, Sekaly RP, Benner C, Hultquist JF, Chanda SK, Garcia Sastre A, Krogan NJ. Integrative Multi-Omics Analysis In Vivo Identifies Influenza A Virus Host Factors. iScience. 22 September 2025.

Whole exome sequencing study of families with single atrium and/or single ventricle identifies de novo mutations in CORIN and TTLL10 as potential pathogenic genes

Authors:
Wu Y, Wang W, Zhou W, Ye B, Chen L, Tang P, Niu J, Han X, Sun X, Qin S, Wang Y
Citation:
Gene. 2025 Sep 22:149786. doi: 10.1016/j.gene.2025.149786. Epub ahead of print. PMID: 40992551
Epub:
Not Epub
Abstract:
Background: Single atrium and/or single ventricle (SA and/or SV) are severe congenital heart malformations linked to gene...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S037811192500575X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y, Wang W, Zhou W, Ye B, Chen L, Tang P, Niu J, Han X, Sun X, Qin S, Wang Y. Whole exome sequencing study of families with single atrium and/or single ventricle identifies de novo mutations in CORIN and TTLL10 as potential pathogenic genes. Gene. 2025 Sep 22:149786. doi: 10.1016/j.gene.2025.149786. Epub ahead of print. PMID: 40992551.

A novel phex gene variant causes non-syndromic tooth agenesis

Authors:
Pan Y, Hua B, Wang H, Tan S, Lu T, Xiong F, Ma D
Citation:
BMC Oral Health 25, 1452 (2025). https://doi.org/10.1186/s12903-025-06827-0
Epub:
Not Epub
Abstract:
Objectives For a long time, phosphate regulating endopeptidase X-linked (phex) gene variants have been considered the primary...
Link:
https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-025-06827-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pan Y, Hua B, Wang H, Tan S, Lu T, Xiong F, Ma D. A novel phex gene variant causes non-syndromic tooth agenesis. BMC Oral Health 25, 1452 (2025). https://doi.org/10.1186/s12903-025-06827-0.

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