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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12092 scientific papers returned from the database with the search filters currently being used below.
There are 12092 scientific papers returned from the database with the search filters currently being used below.
CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair
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Citation:
bioRxiv [Preprint]. 2024 Mar 6:2024.03.06.583756. doi: 10.1101/2024.03.06.583756 Epub:
Not Epub Abstract:
CD47 is a ubiquitous and pleiotropic cell-surface receptor. Disrupting CD47 enhances injury repair in various tissues but the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Mouse Citation Extract: Zondervan RL, Capobianco CA, Jenkins DC, Reicha JD, Fredrick LM, Lam C, Isenberg JS, Ahn J, Marcucio RS, Hankenson KD. CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair. bioRxiv [Preprint]. 2024 Mar 6:2024.03.06.583756. doi: 10.1101/2024.03.06.583756. |
PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis
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Citation:
Autophagy. 2024 Mar 27:1-23. doi: 10.1080/15548627.2024.2333164. Online ahead of print. Epub:
Not Epub Abstract:
PLD1 has been implicated in cytoskeletal reorganization and vesicle trafficking in somatic cells; however, its function remains... Organism or Cell Type:
mouse oocyte Citation Extract: Zhang J, Tian Y, Xu X, Wang B, Huang Z, Song K, Lou S, Kang J, Zhang N, Li J, Weng J, Liang Y, Ma W. PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis. Autophagy. 2024 Mar 27:1-23. doi: 10.1080/15548627.2024.2333164. Online ahead of print.. |
Fbrsl1 is required for heart development in Xenopus laevis and de novo variants in FBRSL1 can cause human heart defects
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Citation:
Dis Model Mech. 2024 Mar 19:dmm.050507. doi: 10.1242/dmm.050507. Online ahead of print Epub:
Not Epub Abstract:
De novo truncating variants in Fibrosin-like protein 1 (FBRSL1), a member of the AUTS2 gene family, cause a disability syndrome... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Berger H, Gerstner S, Horstmann MF, Pauli S, Borchers A. Fbrsl1 is required for heart development in Xenopus laevis and de novo variants in FBRSL1 can cause human heart defects. Dis Model Mech. 2024 Mar 19:dmm.050507. doi: 10.1242/dmm.050507. Online ahead of print. |
CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair
|
Citation:
bioRxiv [Preprint]. 2024 Mar 6:2024.03.06.583756. doi: 10.1101/2024.03.06.583756 Epub:
Not Epub Abstract:
CD47 is a ubiquitous and pleiotropic cell-surface receptor. Disrupting CD47 enhances injury repair in various tissues but the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Mouse Citation Extract: Zondervan RL, Capobianco CA, Jenkins DC, Reicha JD, Fredrick LM, Lam C, Isenberg JS, Ahn J, Marcucio RS, Hankenson KD. CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair. bioRxiv [Preprint]. 2024 Mar 6:2024.03.06.583756. doi: 10.1101/2024.03.06.583756. |
An antisense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo
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Citation:
Am J Physiol Heart Circ Physiol. 2024 Mar 1;326(3):H860-H869. doi: 10.1152/ajpheart.00745.2023 Epub:
Not Epub Abstract:
Targeting alternative exons for therapeutic gain has been achieved in a few instances and potentially could be applied more... Delivery Method:
Vivo Morpholino Organism or Cell Type:
Cell Culture Citation Extract: Damacena de Angelis C, Meddeb M, Chen N, Fisher SA. An antisense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo. Am J Physiol Heart Circ Physiol. 2024 Mar 1;326(3):H860-H869. doi: 10.1152/ajpheart.00745.2023. |
Catechol-Siderophore Mimics Convey Nucleic Acid Therapeutics into Bacteria
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Citation:
Angew Chem Int Ed Engl. 2024 Feb 26:e202402405. doi: 10.1002/anie.202402405. Online ahead of print Epub:
Not Epub Abstract:
Antibacterial resistance is a major threat for human health. There is a need for new antibacterials to stay ahead of constantly... Delivery Method:
siderophore conjugate Organism or Cell Type:
Escherichia coli K12 MG1655 and Acinetobacter baumannii (ATCC19606) Citation Extract: Pals M, Wijnberg L, Yildiz C, Velema WA. Catechol-Siderophore Mimics Convey Nucleic Acid Therapeutics into Bacteria. Angew Chem Int Ed Engl. 2024 Feb 26:e202402405. doi: 10.1002/anie.202402405. Online ahead of print. |
A side-by-side comparison of peptide-delivered antisense antibiotics employing different nucleotide mimics
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Citation:
RNA. 2024 Feb 27:rna.079969.124. doi: 10.1261/rna.079969.124. Online ahead of print Epub:
Not Epub Abstract:
Antisense oligomer (ASO)-based antibiotics that target mRNAs of essential bacterial genes have great potential for... Delivery Method:
peptide-linked Organism or Cell Type:
Salmonella Citation Extract: Ghosh C, Popella L, Dhamodharan V, Jung J, Dietzsch J, Barquist L, Höbartner C, Vogel J. A side-by-side comparison of peptide-delivered antisense antibiotics employing different nucleotide mimics. RNA. 2024 Feb 27:rna.079969.124. doi: 10.1261/rna.079969.124. Online ahead of print. |
Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline
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Citation:
Nucleic Acids Res. 2024 Feb 27:gkae135. doi: 10.1093/nar/gkae135. Online ahead of print Epub:
Not Epub Abstract:
The field of synthetic nucleic acids with novel backbone structures [xenobiotic nucleic acids (XNAs)] has flourished due to the... Citation Extract: Rihon J, Mattelaer CA, Montalvão RW, Froeyen M, Pinheiro VB, Lescrinier E. Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline. Nucleic Acids Res. 2024 Feb 27:gkae135. doi: 10.1093/nar/gkae135. Online ahead of print. |
Direct Activation of Nucleobases with Small Molecules for the Conditional Control of Antisense Function
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Citation:
Angew Chem Int Ed Engl. 2024 Feb 27:e202318773. doi: 10.1002/anie.202318773. Online ahead of print Epub:
Not Epub Abstract:
Conditionally controlled antisense oligonucleotides provide precise interrogation of gene function at different developmental... Delivery Method:
Endo-Porter PEG, microinjection Organism or Cell Type:
cell culture: HEK293T zebrafish Xenopus laevis Citation Extract: Bardhan A, Brown W, Albright S, Tsang M, Davidson L, Deiters A. Direct Activation of Nucleobases with Small Molecules for the Conditional Control of Antisense Function. Angew Chem Int Ed Engl. 2024 Feb 27:e202318773. doi: 10.1002/anie.202318773. Online ahead of print. |
A vertebrate Vangl2 translational variant required for planar cell polarity
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Citation:
J Biol Chem. 2024 Feb 23:106792. doi: 10.1016/j.jbc.2024.106792. Online ahead of print Epub:
Not Epub Abstract:
First described in the milkweed bug Oncopeltus Fasciatus, planar cell polarity (PCP) is a developmental process essential for... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Walton A, Thomé V, Revinski D, Marchetto S, Puvirajesinghe TM, Audebert S, Camoin L, Bailly E, Kodjabachian L, Borg JP. A vertebrate Vangl2 translational variant required for planar cell polarity. J Biol Chem. 2024 Feb 23:106792. doi: 10.1016/j.jbc.2024.106792. Online ahead of print. |