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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

CCSer2 gates dynein activity at the cell periphery

Authors:
Zang JL, Gibson D, Zheng AM, Shi W, Gillies JP, Stein C, Drerup CM, DeSantis ME
Citation:
bioRxiv [preprint] 2024.06.13.598865; doi: https://doi.org/10.1101/2024.06.13.598865
Epub:
Not Epub
Abstract:
Cytoplasmic dynein-1 (dynein) is a microtubule-associated, minus end-directed motor that traffics hundreds of different cargos...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zang JL, Gibson D, Zheng AM, Shi W, Gillies JP, Stein C, Drerup CM, DeSantis ME. CCSer2 gates dynein activity at the cell periphery. bioRxiv [preprint] 2024.06.13.598865; doi: https://doi.org/10.1101/2024.06.13.598865.

Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retina

Authors:
Lu C & Hyde DR
Citation:
Front. Cell Dev. Biol., 13 June 2024. Sec. Molecular and Cellular Pathology. Volume 12 - 2024
Epub:
Not Epub
Abstract:
Zebrafish possess the ability to regenerate dying neurons in response to retinal injury, with both Müller glia and microglia...
Delivery Method:
intravitreal injection and electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Lu C & Hyde DR. Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retina. Front. Cell Dev. Biol., 13 June 2024. Sec. Molecular and Cellular Pathology. Volume 12 - 2024.

Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions

Authors:
Tanaka K, Chen M, Prendergast A, Zhuang Z, Nasiri A, Joshi D, Hintzen J, Chung M, Kumar A, Mani A, Koleske A, Crawford J, Nicoli S, Schwartz MA
Citation:
EMBO J. 2024 Jun 17. doi: 10.1038/s44318-024-00142-0. Epub ahead of print. PMID: 38886581
Epub:
Not Epub
Abstract:
Endothelial cell responses to fluid shear stress from blood flow are crucial for vascular development, function, and disease. A...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka K, Chen M, Prendergast A, Zhuang Z, Nasiri A, Joshi D, Hintzen J, Chung M, Kumar A, Mani A, Koleske A, Crawford J, Nicoli S, Schwartz MA. Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions. EMBO J. 2024 Jun 17. doi: 10.1038/s44318-024-00142-0. Epub ahead of print. PMID: 38886581.

A β-catenin chromobody-based probe highlights endothelial maturation during vascular morphogenesis in vivo

Authors:
Gauvrit S, Zhao S, Rothbauer U, Stainier DYR
Citation:
Development. 2024 Jun 1;151(11):dev202122. doi: 10.1242/dev.202122. Epub 2024 Jun 7. PMID: 38847494.
Epub:
Not Epub
Abstract:
Visualization of protein dynamics is a crucial step in understanding cellular processes. Chromobodies, fluorescently labelled...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gauvrit S, Zhao S, Rothbauer U, Stainier DYR. A β-catenin chromobody-based probe highlights endothelial maturation during vascular morphogenesis in vivo. Development. 2024 Jun 1;151(11):dev202122. doi: 10.1242/dev.202122. Epub 2024 Jun 7. PMID: 38847494..

Hematopoietic stem cell division is governed by distinct RUNX1 binding partners

Authors:
Robertson AL, Yue L, Choudhuri A, Kubaczka C, Wattrus SJ, Mandelbaum J, Avagyan S, Yang S, Freeman RJ, Chan V, Blair MC, Daley GQ, Zon LI
Citation:
bioRxiv [Preprint]. 2024 Jun 8:2024.06.07.596542. doi: 10.1101/2024.06.07.596542. PMID: 38895208; PMCID: PMC11185638
Epub:
Not Epub
Abstract:
A defined number of hematopoietic stem cell (HSC) clones are born during development and expand to form the pool of adult stem...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Robertson AL, Yue L, Choudhuri A, Kubaczka C, Wattrus SJ, Mandelbaum J, Avagyan S, Yang S, Freeman RJ, Chan V, Blair MC, Daley GQ, Zon LI. Hematopoietic stem cell division is governed by distinct RUNX1 binding partners. bioRxiv [Preprint]. 2024 Jun 8:2024.06.07.596542. doi: 10.1101/2024.06.07.596542. PMID: 38895208; PMCID: PMC11185638.

Fine-Tuning Amyloid Precursor Protein Expression through Nonsense-Mediated mRNA Decay

Authors:
Rahmati M, Chebli J, Kumar Banote R, Roselli S, Agholme L, Zetterberg H, Abramsson A
Citation:
eNeuro. 2024 Jun 10;11(6):ENEURO.0034-24.2024. doi: 10.1523/ENEURO.0034-24.2024. PMID: 38789273; PMCID: PMC11164851
Epub:
Not Epub
Abstract:
Studies on genetic robustness recently revealed transcriptional adaptation (TA) as a mechanism by which an organism can...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rahmati M, Chebli J, Kumar Banote R, Roselli S, Agholme L, Zetterberg H, Abramsson A. Fine-Tuning Amyloid Precursor Protein Expression through Nonsense-Mediated mRNA Decay. eNeuro. 2024 Jun 10;11(6):ENEURO.0034-24.2024. doi: 10.1523/ENEURO.0034-24.2024. PMID: 38789273; PMCID: PMC11164851.

Sex-dependent regulation of vertebrate somatic growth and aging by germ cells

Authors:
Abe K, Ino H, Niwa T, Semmy D, Takaochi A, Nishimura T, Mogi C, Uenaka M, Ishii M, Tanaka K, Ohkawa Y, Ishitani T
Citation:
Sci Adv. 2024 Jun 14;10(24):eadi1621. doi: 10.1126/sciadv.adi1621. Epub 2024 Jun 12. PMID: 38865462; PMCID: PMC11168456.
Epub:
Not Epub
Abstract:
The function of germ cells in somatic growth and aging has been demonstrated in invertebrate models but remains unclear in...
Delivery Method:
microinjection
Organism or Cell Type:
Nothobranchius furzeri
Citation Extract:
Abe K, Ino H, Niwa T, Semmy D, Takaochi A, Nishimura T, Mogi C, Uenaka M, Ishii M, Tanaka K, Ohkawa Y, Ishitani T. Sex-dependent regulation of vertebrate somatic growth and aging by germ cells. Sci Adv. 2024 Jun 14;10(24):eadi1621. doi: 10.1126/sciadv.adi1621. Epub 2024 Jun 12. PMID: 38865462; PMCID: PMC11168456..

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility

Authors:
McCluskey KE, Stovell KM, Law K, Kostyanovskaya E, Schmidt J, Exner CRT, Dea J, Brimble E, State MW, Willsey J, Willsey HR
Citation:
bioRxiv [preprint] 2024.05.28.593642; doi: https://doi.org/10.1101/2024.05.28.593642
Epub:
Not Epub
Abstract:
The comorbidity of autism spectrum disorders and severe gastrointestinal symptoms is well-established, yet the molecular...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
McCluskey KE, Stovell KM, Law K, Kostyanovskaya E, Schmidt J, Exner CRT, Dea J, Brimble E, State MW, Willsey J, Willsey HR. Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility. bioRxiv [preprint] 2024.05.28.593642; doi: https://doi.org/10.1101/2024.05.28.593642.

Tumor pretargeting in mice using MORF conjugated CC49 antibody and radiolabeled complimentary cMORF effector

Authors:
Liu G, Dou S, Pretorius PH, Liu X, Chen L, Rusckowski M, Hnatowich DJ
Citation:
Q J Nucl Med Mol Imaging. 2010 Jun;54(3):333-40. Epub 2009 Dec 15. PMID: 20639818; PMCID: PMC2939249
Epub:
Not Epub
Abstract:
We previously reported high CD46 expression in prostate cancer and developed an antibody-drug conjugate and immunoPET agent...
Delivery Method:
antibody-conjugate; in vivo: intravenous
Organism or Cell Type:
LS174T cells; Swiss NIH nude mice explant
Citation Extract:
Liu G, Dou S, Pretorius PH, Liu X, Chen L, Rusckowski M, Hnatowich DJ. Tumor pretargeting in mice using MORF conjugated CC49 antibody and radiolabeled complimentary cMORF effector. Q J Nucl Med Mol Imaging. 2010 Jun;54(3):333-40. Epub 2009 Dec 15. PMID: 20639818; PMCID: PMC2939249.

Nkd1 functions downstream of Axin2 to attenuate Wnt signaling

Authors:
Bell I, Khan H, Stutt N, Horn M, Hydzik T, Lum W, Rea V, Clapham E, Hoeg L, Van Raay TJ
Citation:
Mol Biol Cell. 2024 Jul 1;35(7):ar93. doi: 10.1091/mbc.E24-02-0059-T. Epub 2024 Apr 24. PMID: 38656801
Epub:
Not Epub
Abstract:
Wnt signaling is a crucial developmental pathway involved in early development as well as stem-cell maintenance in adults and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bell I, Khan H, Stutt N, Horn M, Hydzik T, Lum W, Rea V, Clapham E, Hoeg L, Van Raay TJ. Nkd1 functions downstream of Axin2 to attenuate Wnt signaling. Mol Biol Cell. 2024 Jul 1;35(7):ar93. doi: 10.1091/mbc.E24-02-0059-T. Epub 2024 Apr 24. PMID: 38656801.

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