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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12263 scientific papers returned from the database with the search filters currently being used below.
There are 12263 scientific papers returned from the database with the search filters currently being used below.
VARS2 deficiency drives seronegative myasthenia gravis pathology via mitochondrial, immune, and neuromuscular dysregulation
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Citation:
Front. Immunol. (2026) 17:1861435 Epub:
Not Epub Abstract:
Seronegative myasthenia gravis (SNMG) is a clinically heterogeneous subtype of myasthenia gravis (MG) that lacks the classical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lyu Z, Yang B, Zhou Y, Shi M, Wang Z, Song S, Zhang X and Tian J. VARS2 deficiency drives seronegative myasthenia gravis pathology via mitochondrial, immune, and neuromuscular dysregulation. Front. Immunol. (2026) 17:1861435. |
Improved nucleic acid sensing, exemplified using pure target DNA sequences, by MO capture probes compared to DNA capture probes, as revealed from PO2-, PO3- and nucleobase mass peaks
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Citation:
RSC Adv. 2026 Sep 17. doi: 10.1039/d6ra03286a. Epub ahead of print Epub:
Not Epub Abstract:
Detection of gene mutations is central to molecular diagnostics. The conventional detection methods that employ DNA capture... Delivery Method:
none Organism or Cell Type:
non-small cell lung cancer patient tumour DNA Citation Extract: Bhattacharya B, Kundu J, Ghosal A, Paul A, Qasim M, Dattasarma S, Mana T, Dutta SS, Sinha S, Dey S, Dasgupta S, Mukhopadhyay R. Improved nucleic acid sensing, exemplified using pure target DNA sequences, by MO capture probes compared to DNA capture probes, as revealed from PO2-, PO3- and nucleobase mass peaks. RSC Adv. 2026 Sep 17. doi: 10.1039/d6ra03286a. Epub ahead of print. |
Mechanical interactions dynamically influence rosette morphogenesis in the migrating zebrafish posterior lateral line primordium
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Citation:
Development. 2026 Jul 1;153(13):dev204973. doi: 10.1242/dev.204973. Epub 2026 Jul 14 Epub:
Not Epub Abstract:
A pre-pattern of Fibroblast growth factor signaling triggers formation of epithelial rosettes as protoneuromasts form... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mukherjee A, Hilzendeger M, Rinvelt A, Fatma S, Schupp M, Dalle Nogare D, Chitnis AB. Mechanical interactions dynamically influence rosette morphogenesis in the migrating zebrafish posterior lateral line primordium. Development. 2026 Jul 1;153(13):dev204973. doi: 10.1242/dev.204973. Epub 2026 Jul 14. |
SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena
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Citation:
J Cell Sci. 2026 Sep 14:jcs.264648 Epub:
Not Epub Abstract:
SPEF1 is a conserved calponin-homology domain protein that decorates the seam of central pair microtubules in the distal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guha M, Vasudevan KK, Jiang YY, Louka P, Sharma N, Parra M, Lechtreck KF, Tomasi RF, Baroud CN, Dupuis-Williams P, Dougherty GW, Omran H, Ozzello C, Pearson CG, Joachimiak E, Wloga D, Nurcombe ZW, Black C, Ghanaeian A, Mougharbel L, Kitzler TM, Bui KH, Gaertig J. SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena. J Cell Sci. 2026 Sep 14:jcs.264648. |
Placode-derived orphan chemokine CXCL14 is critical for proper chick trigeminal ganglion formation
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Citation:
Dev Biol. 2026 Sep;537:62-70. doi: 10.1016/j.ydbio.2026.06.001. Epub 2026 Jun 8 Epub:
Not Epub Abstract:
The trigeminal ganglion, the largest of cranial sensory ganglia, has a dual origin from neural crest and ectodermal placode... Delivery Method:
injection Organism or Cell Type:
Gallus gallus (chick) embryo Citation Extract: Urrutia HA, Gao J, Bronner ME. Placode-derived orphan chemokine CXCL14 is critical for proper chick trigeminal ganglion formation. Dev Biol. 2026 Sep;537:62-70. doi: 10.1016/j.ydbio.2026.06.001. Epub 2026 Jun 8. |
Tmlhe deficiency induces neurodevelopmental dysfunction and synaptic excitatory/inhibitory imbalance linked to autism-like phenotypes in zebrafish
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Citation:
Prog Neuropsychopharmacol Biol Psychiatry. 2026 Sep 10;150:111927 Epub:
Not Epub Abstract:
Mutations in TMLHE, the initial enzyme for carnitine biosynthesis, are linked to autism spectrum disorder (ASD). However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li J, Zhao X, Wei J, Yang W, Li R, Zhou X, Tian M, Li D, Yan X, Liu C, Zhang Y. Tmlhe deficiency induces neurodevelopmental dysfunction and synaptic excitatory/inhibitory imbalance linked to autism-like phenotypes in zebrafish. Prog Neuropsychopharmacol Biol Psychiatry. 2026 Sep 10;150:111927. |
SafeSense: An open-access safety atlas for antisense oligonucleotides adverse events in human
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Citation:
Mol Ther Nucleic Acids. 2026 Jul 23;37(3):103035 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) therapeutics are a powerful class of RNA-targeted therapy, with applications ranging from... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Vaknin N, Ziv A, Chernobylsky T, Avkin-Nachum S, Rechavi G, Dominissini D, Mor N, N=1 Collaborative. SafeSense: An open-access safety atlas for antisense oligonucleotides adverse events in human. Mol Ther Nucleic Acids. 2026 Jul 23;37(3):103035. |
Genetic evidence and cross-species functional characterization implicate CNN2 in age-related macular degeneration susceptibility
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Citation:
Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2533682123. doi: 10.1073/pnas.2533682123. Epub 2026 Sep 2. PMID: 42685076 Epub:
Not Epub Abstract:
Age-related macular degeneration (AMD) is a leading cause of irreversible visual impairment in the aging population globally.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng FF, Mou H, Liu Z, Zhang CJ, Zhuang YY, Wu Z, Wen XR, Xue A, Zhang X, Yang J, Jin ZB. Genetic evidence and cross-species functional characterization implicate CNN2 in age-related macular degeneration susceptibility. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2533682123. doi: 10.1073/pnas.2533682123. Epub 2026 Sep 2. PMID: 42685076. |
Tissue flow acts as a guidance cue for immune cell polarization and directional migration
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Citation:
Nat Cell Biol. 2026 Sep 7. doi: 10.1038/s41556-026-02058-9. Epub ahead of print. PMID: 42706384 Epub:
Not Epub Abstract:
Embryonic myeloid (EM) cells are the first immune-cell population to emerge during development and must disperse throughout the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Le HA, Hartmann J, Alert R, Mayor R. Tissue flow acts as a guidance cue for immune cell polarization and directional migration. Nat Cell Biol. 2026 Sep 7. doi: 10.1038/s41556-026-02058-9. Epub ahead of print. PMID: 42706384. |
NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency in NF2-SWN iPSC-derived spheroid model
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Citation:
Mol Ther Nucleic Acids. 2026 Aug 3;37(3):103046. doi: 10.1016/j.omtn.2026.103046. PMID: 42662719; PMCID: PMC13520096 Epub:
Not Epub Abstract:
NF2-related schwannomatosis (NF2-SWN) is an inherited autosomal dominant disorder resulting from loss-of-function mutations in... Delivery Method:
Endo-Porter, Vivo-Morpholino Organism or Cell Type:
NF2-SWN iPSC-derived spheroids Citation Extract: Casals-Sendra G, Jarne-Sanz I, Catasús N, Boluda-Luis I, Quer A, Amilibia E, Plotkin SR, Lázaro C, Serra E, Blanco I, Castellanos E. NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency in NF2-SWN iPSC-derived spheroid model. Mol Ther Nucleic Acids. 2026 Aug 3;37(3):103046. doi: 10.1016/j.omtn.2026.103046. PMID: 42662719; PMCID: PMC13520096. |