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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11661 scientific papers returned from the database with the search filters currently being used below.

Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells

Authors:
Leung AO, Yiu TC, Liu L, Tam HY, Gu S, Tu J, Pei D, Cheung HH
Citation:
Cell Biosci. 2022 Dec 31;12(1):212. doi: 10.1186/s13578-022-00939-8
Epub:
Not Epub
Abstract:
Background: Pathogenic mutations in WRN are a cause of premature aging disease Werner syndrome (WS). Besides accelerated aging...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leung AO, Yiu TC, Liu L, Tam HY, Gu S, Tu J, Pei D, Cheung HH. Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells. Cell Biosci. 2022 Dec 31;12(1):212. doi: 10.1186/s13578-022-00939-8.

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish

Authors:
Saralahti AK, Harjula S-KE, Rantapero T, Uusi-Mäkelä MIE, Kaasinen M, Junno M, Piippo H, Nykter M, Lohi O, Rounioja S, Parikka M, Rämet M
Citation:
PLoS Genet. 2023;19(1):e1010586. doi:10.1371/journal.pgen.1010586
Epub:
Not Epub
Abstract:
Streptococcus pneumoniae (pneumococcus) is one of the most frequent causes of pneumonia, sepsis and meningitis in humans, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saralahti AK, Harjula S-KE, Rantapero T, Uusi-Mäkelä MIE, Kaasinen M, Junno M, Piippo H, Nykter M, Lohi O, Rounioja S, Parikka M, Rämet M. Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. PLoS Genet. 2023;19(1):e1010586. doi:10.1371/journal.pgen.1010586.

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish

Authors:
Hayashiji N, Kawahara G, Xu X, Fukuda T, Kerever A, Gu J, Hayashi YK, Arikawa-Hirasawa E
Citation:
Cells. 2022 Dec 29;12(1):144. doi: 10.3390/cells12010144
Epub:
Not Epub
Abstract:
Glycosylation is an important mechanism regulating various biological processes, including intercellular signaling and adhesion...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hayashiji N, Kawahara G, Xu X, Fukuda T, Kerever A, Gu J, Hayashi YK, Arikawa-Hirasawa E. α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish. Cells. 2022 Dec 29;12(1):144. doi: 10.3390/cells12010144.

The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation

Authors:
Cheng Y, Zhang Z, Zhang G, Chen L, Zeng C, Liu X, Feng Y
Citation:
Cells. 2022 Dec 20;12(1):4. doi: 10.3390/cells12010004
Epub:
Not Epub
Abstract:
Many expression data showed miRNAs have a potential function on regulating gonadal differentiation in animals, but their...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Cheng Y, Zhang Z, Zhang G, Chen L, Zeng C, Liu X, Feng Y. The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation. Cells. 2022 Dec 20;12(1):4. doi: 10.3390/cells12010004.

Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier

Authors:
Jonusaite S, Oulhen N, Izumi Y, Furuse M, Yamamoto T, Sakamoto N, Wessel G, Heyland A
Citation:
Dev Biol. 2022 Dec 29;495:21-34. doi: 10.1016/j.ydbio.2022.12.007. Online ahead of print
Epub:
Not Epub
Abstract:
Septate junctions (SJs) evolved as cell-cell junctions that regulate the paracellular barrier and integrity of epithelia in...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Jonusaite S, Oulhen N, Izumi Y, Furuse M, Yamamoto T, Sakamoto N, Wessel G, Heyland A. Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier. Dev Biol. 2022 Dec 29;495:21-34. doi: 10.1016/j.ydbio.2022.12.007. Online ahead of print.

Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes

Authors:
Song K, Jiang X, Xu X, Chen Y, Zhang J, Tian Y, Wang Q, Weng J, Liang Y, Ma W
Citation:
Cell Prolif. 2022 Dec 29:e13391. doi: 10.1111/cpr.13391. Online ahead of print
Epub:
Not Epub
Abstract:
Ste20-like kinase (SLK) is involved in cell proliferation and migration in somatic cells. This study aims to explore SLK...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Song K, Jiang X, Xu X, Chen Y, Zhang J, Tian Y, Wang Q, Weng J, Liang Y, Ma W. Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes. Cell Prolif. 2022 Dec 29:e13391. doi: 10.1111/cpr.13391. Online ahead of print.

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development

Authors:
Li W, Wen L, Rathod B, Gingras AC, Ley K, Lee HS
Citation:
Life Sci Alliance. 2022 Dec 27;6(3):e202201800. doi: 10.26508/lsa.202201800. Print 2023 Mar
Epub:
Not Epub
Abstract:
Direct contact between cells expressing either ephrin ligands or Eph receptor tyrosine kinase produces diverse developmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li W, Wen L, Rathod B, Gingras AC, Ley K, Lee HS. Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development. Life Sci Alliance. 2022 Dec 27;6(3):e202201800. doi: 10.26508/lsa.202201800. Print 2023 Mar.

Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events

Authors:
Maryu G, Yang Q
Citation:
Cell Rep. 2022 Dec 27;41(13):111870. doi: 10.1016/j.celrep.2022.111870
Epub:
Not Epub
Abstract:
The cyclin-dependent kinase (Cdk1) oscillator is widely characterized in homogenized cytosolic extracts, leaving unclear the...
Delivery Method:
mixing into cycling egg extracts in microemulsion droplets
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Maryu G, Yang Q. Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events. Cell Rep. 2022 Dec 27;41(13):111870. doi: 10.1016/j.celrep.2022.111870.

Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish

Authors:
Grossi I, Schiavone M, Cannone E, Grejdan OA, Tobia C, Bonomini F, Rezzani R, Salvi A, De Petro G
Citation:
Genes. 2023;14(1):35. doi:10.3390/genes14010035
Epub:
Not Epub
Abstract:
The LIM and SH3 domain protein 1 (LASP1) was originally identified in metastatic breast cancer and mainly characterized as a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grossi I, Schiavone M, Cannone E, Grejdan OA, Tobia C, Bonomini F, Rezzani R, Salvi A, De Petro G. Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish. Genes. 2023;14(1):35. doi:10.3390/genes14010035.

Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish

Authors:
Ma J, Gu Y, Liu J, Song J, Zhou T, Jiang M, Wen Y, Guo X, Zhou Z, Sha J, He J, Hu Z, Luo L, Liu M
Citation:
Cell Mol Life Sci. 2022 Dec 27;80(1):19. doi: 10.1007/s00018-022-04669-5
Epub:
Not Epub
Abstract:
Congenital heart disease (CHD) is the most common birth defect worldwide and a main cause of perinatal and infant mortality....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma J, Gu Y, Liu J, Song J, Zhou T, Jiang M, Wen Y, Guo X, Zhou Z, Sha J, He J, Hu Z, Luo L, Liu M. Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish. Cell Mol Life Sci. 2022 Dec 27;80(1):19. doi: 10.1007/s00018-022-04669-5.

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