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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation
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Citation:
Nat Commun. 2023 Apr 13;14(1):2115. doi: 10.1038/s41467-023-37745-w Epub:
Not Epub Abstract:
The metameric pattern of somites is created based on oscillatory expression of clock genes in presomitic mesoderm. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yabe T, Uriu K, Takada S. Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation. Nat Commun. 2023 Apr 13;14(1):2115. doi: 10.1038/s41467-023-37745-w. |
TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.04.12.536513 Epub:
Not Epub Abstract:
Defects in blood development frequently occur among syndromic congenital anomalies. Thrombocytopenia-Absent Radius (TAR)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kocere A, Chiavacci E, Méndez-Acevedo KM, Soneson C, Hiltabidle MS, MacGowan JS, Panáková D, Williams MLK, Robinson MD, Mosimann C, Burger A. TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling. bioRxiv. 2023;[preprint] doi:10.1101/2023.04.12.536513 . |
Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA's role in regulating miR-999
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Citation:
Nat Commun. 2023 Apr 13;14(1):2108. doi: 10.1038/s41467-023-37819-9 Epub:
Not Epub Abstract:
MicroRNAs (miRNA) load onto AGO proteins to target mRNAs for translational repression or degradation. However, miRNA... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Drosophila S2 Citation Extract: Sheng P, Li L, Li T, Wang Y, Hiers NM, Mejia JS, Sanchez JS, Zhou L, Xie M. Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA's role in regulating miR-999. Nat Commun. 2023 Apr 13;14(1):2108. doi: 10.1038/s41467-023-37819-9. |
A Realistic Mixture of Persistent Organic Pollutants Affects Zebrafish Development, Behavior, and Specifically Eye Formation by Inhibiting the Condensin I Complex
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Citation:
Toxics. 2023;11(4):357. doi:10.3390/toxics11040357 Epub:
Not Epub Abstract:
Persistent organic pollutants (POPs) are posing major environmental and health threats due to their stability, ubiquity, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guerrero-Limón G, Nivelle R, Bich-Ngoc N, Duy-Thanh D, Muller M. A Realistic Mixture of Persistent Organic Pollutants Affects Zebrafish Development, Behavior, and Specifically Eye Formation by Inhibiting the Condensin I Complex. Toxics. 2023;11(4):357. doi:10.3390/toxics11040357. |
Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue
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Citation:
J Neurosci Res. 2023 Apr 9. doi: 10.1002/jnr.25197. Online ahead of print Epub:
Yes Abstract:
Classical dynamins (DNMs) are GTPase proteins engaged in endocytosis, a fundamental process for cargo internalization from the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bragato C, Pistocchi A, Bellipanni G, Confalonieri S, Balciunie J, Monastra FM, Carra S, Vitale G, Mantecca P, Cotelli F, Gaudenzi G. Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue. J Neurosci Res. 2023 Apr 9. doi: 10.1002/jnr.25197. Online ahead of print. |
Enhancement of zebrafish sperm production via a large body-sized surrogate with germ cell transplantation
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Citation:
Commun Biol. 2023 Apr 14;6(1):412. doi: 10.1038/s42003-023-04800-7 Epub:
Not Epub Abstract:
Zebrafish (Danio rerio) is a commonly-used vertebrate model species for many research areas. However, its low milt volume... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nayak R, Franěk R, Šindelka R, Pšenička M.. Enhancement of zebrafish sperm production via a large body-sized surrogate with germ cell transplantation. Commun Biol. 2023 Apr 14;6(1):412. doi: 10.1038/s42003-023-04800-7. |
miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury
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Citation:
Hepatol Commun. 2023 Apr 4;7(4):e0089. doi: 10.1097/HC9.0000000000000089. eCollection 2023 Apr Epub:
Not Epub Abstract:
Background: Alcohol-associated liver disease (ALD) is a syndrome of progressive inflammatory liver injury and vascular... Link:
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Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Wan Y, Slevin E, Koyama S, Huang CK, Shetty AK, Li X, Harrison K, Li T, Zhou B, Lorenzo SR, Zhang Y, Salinas JM, Xu W, Klaunig JE, Wu C, Tsukamoto H, Meng F. miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury. Hepatol Commun. 2023 Apr 4;7(4):e0089. doi: 10.1097/HC9.0000000000000089. eCollection 2023 Apr. |
Correction of Clcn1 alternative splicing reverses muscle fiber type transition in mice with myotonic dystrophy
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Citation:
Nat Commun. 2023 Apr 7;14(1):1956. doi: 10.1038/s41467-023-37619-1 Epub:
Not Epub Abstract:
In myotonic dystrophy type 1 (DM1), deregulated alternative splicing of the muscle chloride channel Clcn1 causes myotonia, a... Delivery Method:
intramuscular injection (i.m.) then electroporation Organism or Cell Type:
mice Citation Extract: Hu N, Kim E, Antoury L, Wheeler TM. Correction of Clcn1 alternative splicing reverses muscle fiber type transition in mice with myotonic dystrophy. Nat Commun. 2023 Apr 7;14(1):1956. doi: 10.1038/s41467-023-37619-1. |
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease
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Citation:
Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2214997120. doi: 10.1073/pnas.2214997120. Epub 2023 Apr 12 Epub:
Not Epub Abstract:
While somatic variants of TRAF7 (Tumor necrosis factor receptor-associated factor 7) underlie anterior skull-base meningiomas,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis and zebrafish Citation Extract: Mishra-Gorur K, Barak T, Kaulen LD, Henegariu O, Jin SC, Aguilera SM, Yalbir E, Goles G, Nishimura S, Miyagishima D, Djenoune L, Altinok S, Rai DK, Viviano S, Prendergast A, Zerillo C, Ozcan K, Baran B, Sencar L, Goc N, Yarman Y, Ercan-Sencicek AG, Bilguvar K, Lifton RP, Moliterno J, Louvi A, Yuan S, Deniz E, Brueckner M, Gunel M. Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2214997120. doi: 10.1073/pnas.2214997120. Epub 2023 Apr 12. |
The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation
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Citation:
Mol Biol Cell. 2023 Apr 12:mbcE22090411. doi: 10.1091/mbc.E22-09-0411. Online ahead of print Epub:
Not Epub Abstract:
Apical constriction results in apical surface reduction in epithelial cells and is a widely used mechanism for epithelial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Baldwin A, Popov IK, Keller R, Wallingford J, Chang C. The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation. Mol Biol Cell. 2023 Apr 12:mbcE22090411. doi: 10.1091/mbc.E22-09-0411. Online ahead of print. |