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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12299 scientific papers returned from the database with the search filters currently being used below.

Identification of Eukaryotic Translation Initiation Factor 4B as a Novel Candidate Gene for Congenital Hypothyroidism

Authors:
Sun F, Zhang RJ, Fang Y, Yan CY, Zhang CR, Wu FY, Yang RM, Han B, Song HD, Zhao SX
Citation:
J Clin Endocrinol Metab. 2024 Nov 18;109(12):3282-3292. doi: 10.1210/clinem/dgae270. PMID: 38654471
Epub:
Not Epub
Abstract:
Context Congenital hypothyroidism (CH) is the most common endocrine disorder in neonates, but its etiology is still poorly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun F, Zhang RJ, Fang Y, Yan CY, Zhang CR, Wu FY, Yang RM, Han B, Song HD, Zhao SX. Identification of Eukaryotic Translation Initiation Factor 4B as a Novel Candidate Gene for Congenital Hypothyroidism. J Clin Endocrinol Metab. 2024 Nov 18;109(12):3282-3292. doi: 10.1210/clinem/dgae270. PMID: 38654471.

The role of ATP-binding Cassette subfamily B member 6 in the inner ear

Authors:
Baril SA, Wilson KA, Shaik MM, Fukuda Y, Umans RA, Barbieri A, Lynch J, Gose T, Myasnikov A, Oldham ML, Wang Y, Zhu J, Fang J, Zuo J, Kalathur RC, Ford RC, Coffin A, Taylor MR, O'Mara ML, Schuetz JD
Citation:
Nat Commun. 2024 Nov 18;15(1):9885. doi: 10.1038/s41467-024-53663-x. PMID: 39557842; PMCID: PMC11574312
Epub:
Not Epub
Abstract:
ABCB6 has been implicated in dyschromatosis universalis hereditaria, a condition characterized by hyperpigmented and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baril SA, Wilson KA, Shaik MM, Fukuda Y, Umans RA, Barbieri A, Lynch J, Gose T, Myasnikov A, Oldham ML, Wang Y, Zhu J, Fang J, Zuo J, Kalathur RC, Ford RC, Coffin A, Taylor MR, O'Mara ML, Schuetz JD. The role of ATP-binding Cassette subfamily B member 6 in the inner ear. Nat Commun. 2024 Nov 18;15(1):9885. doi: 10.1038/s41467-024-53663-x. PMID: 39557842; PMCID: PMC11574312.

Identification and functional characterization of CD209 homologous genes in zebrafish

Authors:
Yang XJ, Huang ZH, Liu W, Zhang WQ, Huang ZB
Citation:
Yi Chuan. 2024 Nov;46(11):947-957. doi: 10.16288/j.yczz.24-181. PMID: 39557479
Epub:
Not Epub
Abstract:
Innate immune responses play a crucial role in maintaining homeostasis, their initiation closely related to pattern recognition...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang XJ, Huang ZH, Liu W, Zhang WQ, Huang ZB. Identification and functional characterization of CD209 homologous genes in zebrafish. Yi Chuan. 2024 Nov;46(11):947-957. doi: 10.16288/j.yczz.24-181. PMID: 39557479.

Spatiotemporal requirements of nuclear β-catenin define early sea urchin embryogenesis

Authors:
Lhomond G, Schubert M, Croce J
Citation:
PLoS Biol. 2024 Nov 12;22(11):e3002880. doi: 10.1371/journal.pbio.3002880. Epub ahead of print. PMID: 39531468
Epub:
Not Epub
Abstract:
Establishment of the 3 primordial germ layers (ectoderm, endoderm, and mesoderm) during early animal development represents an...
Delivery Method:
microinjection; UV-photocleavable Morpholino
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Lhomond G, Schubert M, Croce J. Spatiotemporal requirements of nuclear β-catenin define early sea urchin embryogenesis. PLoS Biol. 2024 Nov 12;22(11):e3002880. doi: 10.1371/journal.pbio.3002880. Epub ahead of print. PMID: 39531468.

The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy

Authors:
Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Marchant J, Romero MR, Diop S, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K
Citation:
Cell Rep. 2024 Aug 27;43(8):114549. doi: 10.1016/j.celrep.2024.114549. Epub 2024 Aug 1. PMID: 39093699; PMCID: PMC11402474
Epub:
Not Epub
Abstract:
CREB-regulated transcription co-activator (CRTC) is activated by Calcineurin (CaN) to regulate gluconeogenic genes. CaN also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Marchant J, Romero MR, Diop S, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K. The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy. Cell Rep. 2024 Aug 27;43(8):114549. doi: 10.1016/j.celrep.2024.114549. Epub 2024 Aug 1. PMID: 39093699; PMCID: PMC11402474.

The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish

Authors:
Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F
Citation:
Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. PMID: 39217144; PMCID: PMC11366026
Epub:
Not Epub
Abstract:
The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been strongly debated. Here, we provide evidence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F. The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish. Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. PMID: 39217144; PMCID: PMC11366026.

Sodium thiosulfate treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating nitric oxide signalling

Authors:
Ott H, Bennewitz K, Zhang X, Prianichnikova M, Sticht C, Poschet G, Kroll J
Citation:
J Physiol. 2024 Sep 12. doi: 10.1113/JP286398. Epub ahead of print. PMID: 39264236
Epub:
Not Epub
Abstract:
Sodium thiosulfate (STS) is gaining increasing attention in research for its potential therapeutic applications across a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ott H, Bennewitz K, Zhang X, Prianichnikova M, Sticht C, Poschet G, Kroll J. Sodium thiosulfate treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating nitric oxide signalling. J Physiol. 2024 Sep 12. doi: 10.1113/JP286398. Epub ahead of print. PMID: 39264236.

Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells

Authors:
Pessoa Rodrigues C, Collins JM, Yang S, Martinez C, Kim JW, Lama C, Nam AS, Alt C, Lin C, Zon LI
Citation:
Science. 2024 Sep 13;385(6714):eadn1629. doi: 10.1126/science.adn1629. Epub 2024 Sep 13. PMID: 39264994
Epub:
Not Epub
Abstract:
Macrophages maintain hematopoietic stem cell (HSC) quality by assessing cell surface Calreticulin (Calr), an "eat-me...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pessoa Rodrigues C, Collins JM, Yang S, Martinez C, Kim JW, Lama C, Nam AS, Alt C, Lin C, Zon LI. Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells. Science. 2024 Sep 13;385(6714):eadn1629. doi: 10.1126/science.adn1629. Epub 2024 Sep 13. PMID: 39264994.

Apoptotic extracellular vesicles carrying Mif regulate macrophage recruitment and compensatory proliferation in neighboring epithelial stem cells during tissue maintenance

Authors:
Essien SA, Ahuja I, Eisenhoffer GT
Citation:
PLoS Biol. 2024 Nov 4;22(11):e3002194. doi: 10.1371/journal.pbio.3002194. Epub ahead of print. PMID: 39495793
Epub:
Not Epub
Abstract:
Apoptotic cells can signal to neighboring cells to stimulate proliferation and compensate for cell loss to maintain tissue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Essien SA, Ahuja I, Eisenhoffer GT. Apoptotic extracellular vesicles carrying Mif regulate macrophage recruitment and compensatory proliferation in neighboring epithelial stem cells during tissue maintenance. PLoS Biol. 2024 Nov 4;22(11):e3002194. doi: 10.1371/journal.pbio.3002194. Epub ahead of print. PMID: 39495793.

Tetracycline and Oxacillin Act Synergistically on Biofilms and Display Increased Efficacy In Vivo Against Staphylococcus aureus

Authors:
Tooke AK, Hodges RE, Pyrah JF, Bayles KW, Renshaw SA, Foster SJ
Citation:
Curr Microbiol. 2024 Nov 6;81(12):447. doi: 10.1007/s00284-024-03959-4. PMID: 39505760; PMCID: PMC11541413
Epub:
Not Epub
Abstract:
Oxacillin (bactericidal) and tetracycline (bacteriostatic) are clinically relevant antibiotics that are routinely prescribed to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tooke AK, Hodges RE, Pyrah JF, Bayles KW, Renshaw SA, Foster SJ. Tetracycline and Oxacillin Act Synergistically on Biofilms and Display Increased Efficacy In Vivo Against Staphylococcus aureus. Curr Microbiol. 2024 Nov 6;81(12):447. doi: 10.1007/s00284-024-03959-4. PMID: 39505760; PMCID: PMC11541413.

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