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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11497 scientific papers returned from the database with the search filters currently being used below.

Antisense Morpholino-Based In Vitro Correction of a Pseudoexon-Generating Variant in the SGCB Gene

Authors:
Magri F, Zanotti S, Salani S, Fortunato F, Ciscato P, Gerevini S, Maggi L, Sciacco M, Moggio M, Corti S, Bresolin N, Comi GP, Ronchi D
Citation:
Int J Mol Sci. 2022;23(17):9817. doi:10.3390/ijms23179817
Epub:
Not Epub
Abstract:
Limb-girdle muscular dystrophies (LGMD) are clinically and genetically heterogenous presentations displaying predominantly...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
human induced pluripotent stem cells (iPSC)
Citation Extract:
Magri F, Zanotti S, Salani S, Fortunato F, Ciscato P, Gerevini S, Maggi L, Sciacco M, Moggio M, Corti S, Bresolin N, Comi GP, Ronchi D. Antisense Morpholino-Based In Vitro Correction of a Pseudoexon-Generating Variant in the SGCB Gene. Int J Mol Sci. 2022;23(17):9817. doi:10.3390/ijms23179817.

Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2

Authors:
Zhang JL, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda HM, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M
Citation:
Matrix Biol. 2022 Aug 22:S0945-053X(22)00103-2. doi: 10.1016/j.matbio.2022.08.009. Online ahead of print
Epub:
Yes
Abstract:
Hemicentins are large proteins of the extracellular matrix that belong to the fibulin family and play pivotal roles during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang JL, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda HM, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M. Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2. Matrix Biol. 2022 Aug 22:S0945-053X(22)00103-2. doi: 10.1016/j.matbio.2022.08.009. Online ahead of print.

Sema4C Is Required for Vascular and Primary Motor Neuronal Patterning in Zebrafish

Authors:
Sheng J, Jiang B, Shi R, Shi L, Liu D
Citation:
Cells. 2022 Aug 15;11(16):2527. doi: 10.3390/cells11162527
Epub:
Not Epub
Abstract:
Endothelial cells (ECs) and neurons share a number of common signaling pathways and molecular mediators to orchestrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sheng J, Jiang B, Shi R, Shi L, Liu D. Sema4C Is Required for Vascular and Primary Motor Neuronal Patterning in Zebrafish. Cells. 2022 Aug 15;11(16):2527. doi: 10.3390/cells11162527.

Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury

Authors:
Pan HC, Chen YH, Fang WC, Wu VC, Sun CY
Citation:
Int J Mol Sci. 2022 Aug 18;23(16):9318. doi: 10.3390/ijms23169318
Epub:
Not Epub
Abstract:
Background: Lysine demethylase 4C (KDM4C) is a nuclear protein that is essential for histone modification and acts as an...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pan HC, Chen YH, Fang WC, Wu VC, Sun CY. Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury. Int J Mol Sci. 2022 Aug 18;23(16):9318. doi: 10.3390/ijms23169318.

Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis

Authors:
Korotkova DD, Gantsova EA, Goryashchenko AS, Eroshkin FM, Serova OV, Sokolov AS, Sharko F, Zhenilo SV, Martynova NY, Petrenko AG, Zaraisky AG, Deyev IE
Citation:
Int J Mol Sci. 2022 Aug 17;23(16):9250. doi: 10.3390/ijms23169250
Epub:
Not Epub
Abstract:
The orphan insulin receptor-related receptor (IRR) encoded by insrr gene is the third member of the insulin receptor family,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Korotkova DD, Gantsova EA, Goryashchenko AS, Eroshkin FM, Serova OV, Sokolov AS, Sharko F, Zhenilo SV, Martynova NY, Petrenko AG, Zaraisky AG, Deyev IE. Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis. Int J Mol Sci. 2022 Aug 17;23(16):9250. doi: 10.3390/ijms23169250.

Functions of block of proliferation 1 during anterior development in Xenopus laevis

Authors:
Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ
Citation:
PLoS One. 2022 Aug 25;17(8):e0273507. doi: 10.1371/journal.pone.0273507. eCollection 2022
Epub:
Not Epub
Abstract:
Block of proliferation 1 (Bop1) is a nucleolar protein known to be necessary for the assembly of the 60S subunit of ribosomes....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ. Functions of block of proliferation 1 during anterior development in Xenopus laevis. PLoS One. 2022 Aug 25;17(8):e0273507. doi: 10.1371/journal.pone.0273507. eCollection 2022.

PTEN inhibits AMPK to control collective migration

Authors:
Peglion F, Capuana L, Perfettini I, Boucontet L, Braithwaite B, Colucci-Guyon E, Quissac E, Forsberg-Nilsson K, Llense F, Etienne-Manneville S
Citation:
Nat Commun. 2022 Aug 11;13(1):4528. doi: 10.1038/s41467-022-31842-y
Epub:
Not Epub
Abstract:
Pten is one of the most frequently mutated tumour suppressor gene in cancer. PTEN is generally altered in invasive cancers such...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peglion F, Capuana L, Perfettini I, Boucontet L, Braithwaite B, Colucci-Guyon E, Quissac E, Forsberg-Nilsson K, Llense F, Etienne-Manneville S. PTEN inhibits AMPK to control collective migration. Nat Commun. 2022 Aug 11;13(1):4528. doi: 10.1038/s41467-022-31842-y.

GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base

Authors:
Jang DG, Kwon KY, Kweon YC, Kim BG, Myung K, Lee HS, Young Park C, Kwon T, Park TJ
Citation:
Elife. 2022 Aug 25;11:e81016. doi: 10.7554/eLife.81016. Online ahead of print
Epub:
Not Epub
Abstract:
The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jang DG, Kwon KY, Kweon YC, Kim BG, Myung K, Lee HS, Young Park C, Kwon T, Park TJ. GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base. Elife. 2022 Aug 25;11:e81016. doi: 10.7554/eLife.81016. Online ahead of print.

TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration

Authors:
Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, Kobin MA, Tartaglia GG, Colantoni A, Proietti G, Wu Y, Hammerschmidt M, De Pittà C, Sales G, Salzman J, Pellizzoni L, Wirth B, Schiavi ED, Gatti M, Artandi SE, Raffa GD
Citation:
Nucleic Acids Res. 2022 Aug 10:gkac659. doi: 10.1093/nar/gkac659. Online ahead of print
Epub:
Not Epub
Abstract:
Trimethylguanosine synthase 1 (TGS1) is a highly conserved enzyme that converts the 5′-monomethylguanosine cap of small nuclear...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, Kobin MA, Tartaglia GG, Colantoni A, Proietti G, Wu Y, Hammerschmidt M, De Pittà C, Sales G, Salzman J, Pellizzoni L, Wirth B, Schiavi ED, Gatti M, Artandi SE, Raffa GD. TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration. Nucleic Acids Res. 2022 Aug 10:gkac659. doi: 10.1093/nar/gkac659. Online ahead of print.

Co-option of the piRNA pathway to regulate neural crest specification

Authors:
Galton R, Fejes-Toth K, Bronner ME
Citation:
Sci Adv. 2022 Aug 12;8(32):eabn1441. doi: 10.1126/sciadv.abn1441. Epub 2022 Aug 10
Epub:
Not Epub
Abstract:
Across Metazoa, Piwi proteins play a critical role in protecting the germline genome through piRNA-mediated repression of...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Galton R, Fejes-Toth K, Bronner ME. Co-option of the piRNA pathway to regulate neural crest specification. Sci Adv. 2022 Aug 12;8(32):eabn1441. doi: 10.1126/sciadv.abn1441. Epub 2022 Aug 10.

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