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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11661 scientific papers returned from the database with the search filters currently being used below.

Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition

Authors:
Piacentino ML, Hutchins EJ, Andrews CJ, Bronner ME
Citation:
Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2212879119. doi: 10.1073/pnas.2212879119. Epub 2022 Dec 12
Epub:
Not Epub
Abstract:
Epithelial-to-mesenchymal transition (EMT) is a dramatic change in cellular physiology during development and metastasis, which...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Piacentino ML, Hutchins EJ, Andrews CJ, Bronner ME. Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2212879119. doi: 10.1073/pnas.2212879119. Epub 2022 Dec 12.

Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia

Authors:
Kwon KY, Jeong H, Jang DG, Kwon T, Park TJ
Citation:
Genes Genomics. 2022 Dec 12. doi: 10.1007/s13258-022-01350-w. Online ahead of print
Epub:
Not Epub
Abstract:
Background: Motile cilia in a vertebrate are important to sustaining activities of life. Fluid flow on the apical surface of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kwon KY, Jeong H, Jang DG, Kwon T, Park TJ. Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia. Genes Genomics. 2022 Dec 12. doi: 10.1007/s13258-022-01350-w. Online ahead of print.

Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway

Authors:
Liu J, Zhang X, Zhang Q, Wang R, Ma J, Bai X, Wang D
Citation:
Front Cell Neurosci. 2022 Nov 24;16:1065309. doi: 10.3389/fncel.2022.1065309. eCollection 2022
Epub:
Not Epub
Abstract:
Background: Mutations in lipoxygenase homology domain 1 (LOXHD1) cause autosomal recessive inheritance, leading to high-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu J, Zhang X, Zhang Q, Wang R, Ma J, Bai X, Wang D. Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway. Front Cell Neurosci. 2022 Nov 24;16:1065309. doi: 10.3389/fncel.2022.1065309. eCollection 2022.

ftr82 is necessary for hair cell morphogenesis and auditory function during zebrafish development

Authors:
Yin G, Qian F, Yao J, Wang Z, Wang X, Liu D, Wang C
Citation:
J Genet Genomics. 2022 Dec 1:S1673-8527(22)00252-1. doi: 10.1016/j.jgg.2022.11.008. Online ahead of print
Epub:
Yes
Abstract:
Damages of sensory hair cells (HCs) are mainly responsible for sensorineural hearing loss, while the pathological mechanism...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin G, Qian F, Yao J, Wang Z, Wang X, Liu D, Wang C. ftr82 is necessary for hair cell morphogenesis and auditory function during zebrafish development. J Genet Genomics. 2022 Dec 1:S1673-8527(22)00252-1. doi: 10.1016/j.jgg.2022.11.008. Online ahead of print.

PPMOs: A Case Study for Cell-Penetrating Peptide Application

Authors:
Bittner S, Moulton ZX, Moulton HM
Citation:
In Cell-Penetrating Peptides (eds M. Oba and Y. Demizu). 2023:ch 15. doi:10.1002/9783527835997.ch15
Epub:
Not Epub
Abstract:
The current state of the art for in vivo antisense morpholino technology is peptide-conjugated phosphorodiamidate morpholino...
Delivery Method:
peptide-linked
Citation Extract:
Bittner S, Moulton ZX, Moulton HM. PPMOs: A Case Study for Cell-Penetrating Peptide Application. In Cell-Penetrating Peptides (eds M. Oba and Y. Demizu). 2023:ch 15. doi:10.1002/9783527835997.ch15.

LOF variants identifying candidate genes of laterality defects patients with congenital heart disease

Authors:
Liu S, Wei W, Wang P, Liu C, Jiang X, Li T, Li F, Wu Y, Chen S, Sun K, Xu R
Citation:
PLoS Genet. 2022;18(12):e1010530. doi:10.1371/journal.pgen.1010530
Epub:
Not Epub
Abstract:
Defects in laterality pattern can result in abnormal positioning of the internal organs during the early stages of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu S, Wei W, Wang P, Liu C, Jiang X, Li T, Li F, Wu Y, Chen S, Sun K, Xu R. LOF variants identifying candidate genes of laterality defects patients with congenital heart disease. PLoS Genet. 2022;18(12):e1010530. doi:10.1371/journal.pgen.1010530.

Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates

Authors:
Faustini G, Longhena F, Muscò A, Bono F, Parrella E, La Via L, Barbon A, Pizzi M, Onofri F, Benfenati F, Missale C, Memo M, Zizioli D, Bellucci A
Citation:
Cells. 2022; 11(23):3902. doi:10.3390/cells11233902
Epub:
Not Epub
Abstract:
.Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by alterations in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Faustini G, Longhena F, Muscò A, Bono F, Parrella E, La Via L, Barbon A, Pizzi M, Onofri F, Benfenati F, Missale C, Memo M, Zizioli D, Bellucci A. Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates. Cells. 2022; 11(23):3902. doi:10.3390/cells11233902.

Viral-induced alternative splicing of host genes promotes influenza replication

Authors:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW
Citation:
Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500
Epub:
Not Epub
Abstract:
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: A549
Citation Extract:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW. Viral-induced alternative splicing of host genes promotes influenza replication. Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500.

Transposable elements drive the evolution of metazoan zinc finger genes

Authors:
Wells JN, Chang N-C, McCormick J, Coleman C, Ramos N, Jin B, Feschotte C
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.29.518450
Epub:
Not Epub
Abstract:
Cys2-His2 Zinc finger genes (ZNFs) form the largest family of transcription factors in metazoans. ZNF evolution is highly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wells JN, Chang N-C, McCormick J, Coleman C, Ramos N, Jin B, Feschotte C. Transposable elements drive the evolution of metazoan zinc finger genes. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.29.518450.

Parental mutations influence wild-type offspring via transcriptional adaptation

Authors:
Jiang Z, El-Brolosy MA, Serobyan V, Welker JM, Retzer N, Dooley CM, Jakutis G, Juan T, Fukuda N, Maischein HM, Balciunas D, Stainier DYR
Citation:
Sci Adv. 2022 Nov 25;8(47):eabj2029. doi: 10.1126/sciadv.abj2029. Epub 2022 Nov 25
Epub:
Not Epub
Abstract:
Transgenerational epigenetic inheritance (TEI) is mostly discussed in the context of physiological or environmental factors....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang Z, El-Brolosy MA, Serobyan V, Welker JM, Retzer N, Dooley CM, Jakutis G, Juan T, Fukuda N, Maischein HM, Balciunas D, Stainier DYR. Parental mutations influence wild-type offspring via transcriptional adaptation. Sci Adv. 2022 Nov 25;8(47):eabj2029. doi: 10.1126/sciadv.abj2029. Epub 2022 Nov 25.

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