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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Cdon is required for organ Left-Right patterning via regulating DFCs migration and the sequential ciliogenesis

Authors:
Deng Z, Chang W, Li C, Li B, Huang S, Huang J, Zhang K, Li Y, Liu X, Ran Q, Guo Z, Huang S
Citation:
bioRxiv [preprint] 2024.03.12.584572; doi: https://doi.org/10.1101/2024.03.12.584572
Epub:
Not Epub
Abstract:
Cdon and boc are members of the cell adhesion molecule subfamily III Ig/fibronectin. Although they were reported to be involved...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Deng Z, Chang W, Li C, Li B, Huang S, Huang J, Zhang K, Li Y, Liu X, Ran Q, Guo Z, Huang S. Cdon is required for organ Left-Right patterning via regulating DFCs migration and the sequential ciliogenesis. bioRxiv [preprint] 2024.03.12.584572; doi: https://doi.org/10.1101/2024.03.12.584572.

Somatostatin signalling coordinates energy metabolism allocation to reproduction in zebrafish

Authors:
Chen J, Zhao W, Cao L, Martins RST, Canário AVM
Citation:
BMC Biol. 2024 Jul 29;22(1):163. doi: 10.1186/s12915-024-01961-7. PMID: 39075492; PMCID: PMC11288053
Epub:
Not Epub
Abstract:
BACKGROUND: Energy allocation between growth and reproduction determines puberty onset and fertility. In mammals, peripheral...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Zhao W, Cao L, Martins RST, Canário AVM. Somatostatin signalling coordinates energy metabolism allocation to reproduction in zebrafish. BMC Biol. 2024 Jul 29;22(1):163. doi: 10.1186/s12915-024-01961-7. PMID: 39075492; PMCID: PMC11288053.

Leucine-Rich Repeat Kinase-2 Controls the Differentiation and Maturation of Oligodendrocytes in Mice and Zebrafish

Authors:
Filippini A, Cannone E, Mazziotti V, Carini G, Mutti V, Ravelli C, Gennarelli M, Schiavone M, Russo I
Citation:
Biomolecules. 2024; 14(7):870. https://doi.org/10.3390/biom14070870
Epub:
Not Epub
Abstract:
Leucine-rich repeat kinase-2 (LRRK2), a gene mutated in familial and sporadic Parkinson’s disease (PD), controls multiple...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Filippini A, Cannone E, Mazziotti V, Carini G, Mutti V, Ravelli C, Gennarelli M, Schiavone M, Russo I. Leucine-Rich Repeat Kinase-2 Controls the Differentiation and Maturation of Oligodendrocytes in Mice and Zebrafish. Biomolecules. 2024; 14(7):870. https://doi.org/10.3390/biom14070870.

SCAR-6 elncRNA locus epigenetically regulates PROZ and modulates coagulation and vascular function

Authors:
Ranjan G, Sehgal P, Scaria V, Sivasubbu S
Citation:
bioRxiv [preprint] 2024.07.21.604148; doi: https://doi.org/10.1101/2024.07.21.604148
Epub:
Not Epub
Abstract:
Syntenic conservation is an effective strategy to identify evolutionarily conserved lncRNA orthologs. In this study, we...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ranjan G, Sehgal P, Scaria V, Sivasubbu S. SCAR-6 elncRNA locus epigenetically regulates PROZ and modulates coagulation and vascular function. bioRxiv [preprint] 2024.07.21.604148; doi: https://doi.org/10.1101/2024.07.21.604148.

Sall4 regulates downstream patterning genes during limb regeneration

Authors:
Erickson JR, Walker SE, Arenas Gomez C, Echeverri K
Citation:
Dev Biol. 2024 Jul 25:S0012-1606(24)00195-7. doi: 10.1016/j.ydbio.2024.07.015. Epub ahead of print. PMID: 39067503.
Epub:
Not Epub
Abstract:
Many salamanders can completely regenerate a fully functional limb. Limb regeneration is a carefully coordinated process...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Erickson JR, Walker SE, Arenas Gomez C, Echeverri K. Sall4 regulates downstream patterning genes during limb regeneration. Dev Biol. 2024 Jul 25:S0012-1606(24)00195-7. doi: 10.1016/j.ydbio.2024.07.015. Epub ahead of print. PMID: 39067503..

Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin and empagliflozin induced arterial relaxation

Authors:
Forrester EA, Benítez-Angeles M, Redford KE, Rosenbaum T, Abbott GW, Barrese V, Dora K, Albert AP, Dannesboe J, Salles-Crawley I, Jepps TA, Greenwood IA
Citation:
Cardiovasc Res. 2024 Jul 26:cvae156. doi: 10.1093/cvr/cvae156. Epub ahead of print. PMID: 39056245.
Epub:
Not Epub
Abstract:
Aims: Sodium/glucose transporter 2 (SGLT2 or SLC5A2) inhibitors lower blood glucose and are also approved treatments for heart...
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
NHE1 knockout mouse explant: mesenteric arteries
Citation Extract:
Forrester EA, Benítez-Angeles M, Redford KE, Rosenbaum T, Abbott GW, Barrese V, Dora K, Albert AP, Dannesboe J, Salles-Crawley I, Jepps TA, Greenwood IA. Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin and empagliflozin induced arterial relaxation. Cardiovasc Res. 2024 Jul 26:cvae156. doi: 10.1093/cvr/cvae156. Epub ahead of print. PMID: 39056245..

CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression

Authors:
Baker CE, Marta AG, Zimmerman ND, Korade Z, Mathy NW, Wilton D, Simeone T, Kochvar A, Kramer KL, Stessman HAF, Shibata A
Citation:
Biomolecules. 2024; 14(8):914
Epub:
Not Epub
Abstract:
Carnitine palmitoyltransferase 2 (CPT2) is an inner mitochondrial membrane protein of the carnitine shuttle and is involved in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baker CE, Marta AG, Zimmerman ND, Korade Z, Mathy NW, Wilton D, Simeone T, Kochvar A, Kramer KL, Stessman HAF, Shibata A. CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression. Biomolecules. 2024; 14(8):914.

Mycb and Mych stimulate Müller glial cell reprogramming and proliferation in the uninjured and injured zebrafish retina

Authors:
Lee MS, Jui J, Sahu A, Goldman D
Citation:
Development. 2024 Jul 10:dev.203062. doi: 10.1242/dev.203062. Epub ahead of print. PMID: 38984586
Epub:
Not Epub
Abstract:
In the injured zebrafish retina, Müller glial cells (MG) reprogram to adopt retinal stem cell properties and regenerate damaged...
Delivery Method:
intravitreal injection and electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Lee MS, Jui J, Sahu A, Goldman D. Mycb and Mych stimulate Müller glial cell reprogramming and proliferation in the uninjured and injured zebrafish retina. Development. 2024 Jul 10:dev.203062. doi: 10.1242/dev.203062. Epub ahead of print. PMID: 38984586.

Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation

Authors:
Chen S, Yin J, Liang J, Zhang W, Jiang P, Wang W, Chen X, Zhou Y, Xia P, Yang F, Gu Y, Zhang R, Han P
Citation:
bioRxiv 2024.05.09.593293; doi: https://doi.org/10.1101/2024.05.09.593293
Epub:
Not Epub
Abstract:
Biomechanical cues play an essential role in sculpting organ formation. Comprehending how cardiac cells perceive and respond to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen S, Yin J, Liang J, Zhang W, Jiang P, Wang W, Chen X, Zhou Y, Xia P, Yang F, Gu Y, Zhang R, Han P. Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation. bioRxiv 2024.05.09.593293; doi: https://doi.org/10.1101/2024.05.09.593293.

Mechanical forces remodel the cardiac extracellular matrix during zebrafish development

Authors:
Gentile A, Albu M, Xu Y, Mortazavi N, Ribeiro da Silva A, Stainier DYR, Gunawan F
Citation:
Development. 2024 Jul 1;151(13):dev202310. doi: 10.1242/dev.202310. Epub 2024 Jul 10. PMID: 38984541
Epub:
Not Epub
Abstract:
The cardiac extracellular matrix (cECM) is fundamental for organ morphogenesis and maturation, during which time it undergoes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gentile A, Albu M, Xu Y, Mortazavi N, Ribeiro da Silva A, Stainier DYR, Gunawan F. Mechanical forces remodel the cardiac extracellular matrix during zebrafish development. Development. 2024 Jul 1;151(13):dev202310. doi: 10.1242/dev.202310. Epub 2024 Jul 10. PMID: 38984541.

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