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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12146 scientific papers returned from the database with the search filters currently being used below.

Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models

Authors:
Zhang H, Shen S, Qian Y, Zhang L, Pu J, Zhou X, Yang N, Wang W
Citation:
Int Dent J. 2025 Aug 27;75(6):103874. doi: 10.1016/j.identj.2025.103874. Epub ahead of print. PMID: 40876387
Epub:
Not Epub
Abstract:
Background: Craniofacial malformations, caused by dysregulated neural crest cell (NCC) differentiation, affect approximately...
Link:
https://www.sciencedirect.com/science/article/pii/S0020653925031600
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang H, Shen S, Qian Y, Zhang L, Pu J, Zhou X, Yang N, Wang W. Role of TGF-β3 in Regulating Neural Crest Cell Fate and Craniofacial Development: Insights From Zebrafish Models. Int Dent J. 2025 Aug 27;75(6):103874. doi: 10.1016/j.identj.2025.103874. Epub ahead of print. PMID: 40876387.

Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential

Authors:
Morizet D, Foucher I, Mignerey I, Alunni A, Bally-Cuif L
Citation:
Sci Adv. 2025 Aug 29;11(35):eadu3189. doi: 10.1126/sciadv.adu3189. Epub 2025 Aug 27. PMID: 40864701; PMCID: PMC12383255
Epub:
Not Epub
Abstract:
In the vertebrate brain, neural stem cell (NSC) quiescence is necessary for stemness maintenance. Using single-cell RNA...
Link:
https://www.science.org/doi/10.1126/sciadv.adu3189
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Morizet D, Foucher I, Mignerey I, Alunni A, Bally-Cuif L. Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential. Sci Adv. 2025 Aug 29;11(35):eadu3189. doi: 10.1126/sciadv.adu3189. Epub 2025 Aug 27. PMID: 40864701; PMCID: PMC12383255.

Determining the importance of the stringent response for methicillin-resistant Staphylococcus aureus virulence in vivo

Authors:
Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA, Corrigan RM
Citation:
J Infect Dis. 2025 Aug 8:jiaf421. doi: 10.1093/infdis/jiaf421. Epub ahead of print. PMID: 40795378
Epub:
Not Epub
Abstract:
The stringent response is a stress signalling pathway with links to bacterial virulence. This pathway is controlled by the...
Link:
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiaf421/8228549
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choudhury NR, Urwin L, Salamaga B, Prince LR, Renshaw SA, Corrigan RM. Determining the importance of the stringent response for methicillin-resistant Staphylococcus aureus virulence in vivo. J Infect Dis. 2025 Aug 8:jiaf421. doi: 10.1093/infdis/jiaf421. Epub ahead of print. PMID: 40795378.

Perfluorodecanoic Acid (PFDA) Disrupts Immune Regulation via the Toll-like Receptor Signaling Pathway in Zebrafish

Authors:
Wang J, Fang D, Magnuson JT, Xu B, Zheng C, Schlenk D, Tang L, Qiu W
Citation:
Environ Sci Technol. 2025 Sep 1. doi: 10.1021/acs.est.5c04320. Epub ahead of print. PMID: 40891081
Epub:
Not Epub
Abstract:
As there are a growing number of per- and polyfluoroalkyl substances (PFAS) alternative substitutes applied globally, it...
Link:
https://pubs.acs.org/doi/10.1021/acs.est.5c04320
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Fang D, Magnuson JT, Xu B, Zheng C, Schlenk D, Tang L, Qiu W. Perfluorodecanoic Acid (PFDA) Disrupts Immune Regulation via the Toll-like Receptor Signaling Pathway in Zebrafish. Environ Sci Technol. 2025 Sep 1. doi: 10.1021/acs.est.5c04320. Epub ahead of print. PMID: 40891081.

In Vivo Phage Display for the Identification of Muscle Homing Peptides to Improve the Delivery of Phosphorodiamidate Morpholino Oligomers for Duchenne Muscular Dystrophy Therapy

Authors:
Schneider AE, Winter CLT, Mei H, Jirka SMG, Tan X, Thompson EG, Ha K, Mitra A, Garcia S, Luimes M, Oliver R, Morgan KY, Guerlavais V, Aartsma-Rus A
Citation:
Nucleic Acid Ther. 2025 Aug 29. doi: 10.1177/21593337251371708. Epub ahead of print. PMID: 40879532
Epub:
Not Epub
Abstract:
The severe X-linked degenerative neuromuscular disease Duchenne muscular dystrophy (DMD) is caused by the loss of dystrophin...
Link:
https://www.liebertpub.com/doi/10.1177/21593337251371708
Delivery Method:
peptide-linked
Organism or Cell Type:
mdx mice
Citation Extract:
Schneider AE, Winter CLT, Mei H, Jirka SMG, Tan X, Thompson EG, Ha K, Mitra A, Garcia S, Luimes M, Oliver R, Morgan KY, Guerlavais V, Aartsma-Rus A. In Vivo Phage Display for the Identification of Muscle Homing Peptides to Improve the Delivery of Phosphorodiamidate Morpholino Oligomers for Duchenne Muscular Dystrophy Therapy. Nucleic Acid Ther. 2025 Aug 29. doi: 10.1177/21593337251371708. Epub ahead of print. PMID: 40879532.

An endogenous cluster of target-directed microRNA degradation sites induces decay of distinct microRNA families

Authors:
Hiers NM, Li L, Li T, Sheng P, Wang Y, Traugot CM, Yao M, Xie M
Citation:
Cell Rep. 2025 Sep 23;44(9):116162. doi: 10.1016/j.celrep.2025.116162. Epub 2025 Aug 19. PMID: 40833851; PMCID: PMC12573233
Epub:
Not Epub
Abstract:
While much is known about microRNA (miRNA) biogenesis and targeting, relatively less is understood about miRNA decay. Target-...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12573233/
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: Drosophila S2
Citation Extract:
Hiers NM, Li L, Li T, Sheng P, Wang Y, Traugot CM, Yao M, Xie M. An endogenous cluster of target-directed microRNA degradation sites induces decay of distinct microRNA families. Cell Rep. 2025 Sep 23;44(9):116162. doi: 10.1016/j.celrep.2025.116162. Epub 2025 Aug 19. PMID: 40833851; PMCID: PMC12573233.

RAB23 loss-of-function mutation causes context-dependent ciliopathy in Carpenter syndrome

Authors:
Leong WY, Tung WL, Wilkie AOM, Hor CHH
Citation:
PLoS Genet. 2025 Aug 18;21(8):e1011611. doi: 10.1371/journal.pgen.1011611. Epub ahead of print. PMID: 40825043
Epub:
Not Epub
Abstract:
The primary cilium is a signal transduction organelle whose dysfunction clinically causes ciliopathies in humans. RAB23 is a...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011611
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leong WY, Tung WL, Wilkie AOM, Hor CHH. RAB23 loss-of-function mutation causes context-dependent ciliopathy in Carpenter syndrome. PLoS Genet. 2025 Aug 18;21(8):e1011611. doi: 10.1371/journal.pgen.1011611. Epub ahead of print. PMID: 40825043.

Segregation of endoderm and mesoderm germ layer identities in the diploblast Nematostella vectensis

Authors:
Haillot E, Lebedeva T, Steger J, Genikhovich G, Montenegro JD, Cole AG, Technau U
Citation:
Nat Commun. 2025 Aug 27;16(1):7979. doi: 10.1038/s41467-025-63287-4. PMID: 40858588; PMCID: PMC12381260
Epub:
Not Epub
Abstract:
A recent study suggested that morphologically diploblastic sea anemones (Cnidaria) have three segregated germ layer identities...
Link:
https://www.nature.com/articles/s41467-025-63287-4
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anenome)
Citation Extract:
Haillot E, Lebedeva T, Steger J, Genikhovich G, Montenegro JD, Cole AG, Technau U. Segregation of endoderm and mesoderm germ layer identities in the diploblast Nematostella vectensis. Nat Commun. 2025 Aug 27;16(1):7979. doi: 10.1038/s41467-025-63287-4. PMID: 40858588; PMCID: PMC12381260.

Supracellular contractility in Xenopus embryo epithelia regulated by extracellular ATP and the purinergic receptor P2Y2

Authors:
Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA
Citation:
J Cell Sci. 2025 Aug 26:jcs.263877. doi: 10.1242/jcs.263877. Epub ahead of print. PMID: 40856002
Epub:
Not Epub
Abstract:
Extracellular signals regulate epithelial homeostasis, cell fate and pattern cell behaviors during embryogenesis, wound healing...
Link:
https://journals.biologists.com/jcs/article/doi/10.1242/jcs.263877/368966/Supracellular-contractility-in-Xenopus-embryo
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA. Supracellular contractility in Xenopus embryo epithelia regulated by extracellular ATP and the purinergic receptor P2Y2. J Cell Sci. 2025 Aug 26:jcs.263877. doi: 10.1242/jcs.263877. Epub ahead of print. PMID: 40856002.

Phospholipase D2 Regulates Microtubule Acetylation by Modulating Gsk3β-Tau Signaling in Mouse Oocytes During Meiotic Maturation

Authors:
Zhang N, Tian Y, Xu X, Wang B, Lou S, Kang J, Li J, Liang Y, Weng J, Ma W
Citation:
Mol Reprod Dev. 2025 Aug;92(8):e70051. doi: 10.1002/mrd.70051. PMID: 40838360
Epub:
Not Epub
Abstract:
Phospholipase D2 (PLD2) modulates cytoskeletal dynamics and membrane trafficking processes by converting phosphatidylcholine (...
Link:
https://onlinelibrary.wiley.com/doi/10.1002/mrd.70051
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Zhang N, Tian Y, Xu X, Wang B, Lou S, Kang J, Li J, Liang Y, Weng J, Ma W. Phospholipase D2 Regulates Microtubule Acetylation by Modulating Gsk3β-Tau Signaling in Mouse Oocytes During Meiotic Maturation. Mol Reprod Dev. 2025 Aug;92(8):e70051. doi: 10.1002/mrd.70051. PMID: 40838360.

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