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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Mature mRNA processing that deletes 3' end sequences directs translational activation and embryonic development
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Citation:
Sci Adv. 2023 Nov 24;9(47):eadg6532. doi: 10.1126/sciadv.adg6532. Epub 2023 Nov 24 Epub:
Not Epub Abstract:
Eggs accumulate thousands of translationally repressed mRNAs that are translated into proteins after fertilization to direct... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Takada Y, Fierro L, Sato K, Sanada T, Ishii A, Yamamoto T, Kotani T. Mature mRNA processing that deletes 3' end sequences directs translational activation and embryonic development. Sci Adv. 2023 Nov 24;9(47):eadg6532. doi: 10.1126/sciadv.adg6532. Epub 2023 Nov 24. |
Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.11.23.568438 Epub:
Not Epub Abstract:
The body plan of vertebrates appears externally bilaterally symmetric. Nonetheless the positioning and morphology of internal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eggeler F, Boulanger-Weill J, De Santis F, Belleri L, Duroure K, Auer TO, Albadri S, Del Bene F. Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry. bioRxiv. 2023;[preprint] doi:10.1101/2023.11.23.568438. |
Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases
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Citation:
Nat Commun. 2023 Nov 23;14(1):7668. doi: 10.1038/s41467-023-43349-1 Epub:
Not Epub Abstract:
Uncovering the mechanisms regulating hematopoietic specification not only would overcome current limitations related to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng X, Barakat R, Pavani G, Usha MK, Calderon R, Snella E, Gorden A, Zhang Y, Gadue P, French DL, Dorman KS, Fidanza A, Campbell CA, Espin-Palazon R. Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases. Nat Commun. 2023 Nov 23;14(1):7668. doi: 10.1038/s41467-023-43349-1. |
ERBB3 deficiency causes a multisystemic syndrome in human patient and zebrafish
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Citation:
Clin Genet. 2023 Nov 27. doi: 10.1111/cge.14462. Online ahead of print Epub:
Yes Abstract:
The Erb-B2 receptor tyrosine kinase 3 (ERBB3) gene was first identified as a cause of lethal congenital contracture syndrome (... Organism or Cell Type:
zebrafish Citation Extract: Liu K, Chen R, Zhang M, Gong Y, Wang Y, Cai W. ERBB3 deficiency causes a multisystemic syndrome in human patient and zebrafish. Clin Genet. 2023 Nov 27. doi: 10.1111/cge.14462. Online ahead of print. |
A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation
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Citation:
Curr Biol. 2023 Nov 14:S0960-9822(23)01515-4. doi: 10.1016/j.cub.2023.11.001. Online ahead of print Epub:
Not Epub Abstract:
Cell and tissue reshaping is crucial for coordinating three-dimensional pattern formation, in which the size and shape of the... Delivery Method:
microinjection Organism or Cell Type:
Ciona savignyi (ascidian) Citation Extract: Peng H, Qiao J, Wang G, Shi W, Xia F, Qiao R, Dong B. A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation. Curr Biol. 2023 Nov 14:S0960-9822(23)01515-4. doi: 10.1016/j.cub.2023.11.001. Online ahead of print. |
mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates
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Citation:
Bioconjug Chem. 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408. Online ahead of print Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are a special type of antisense oligonucleotides (ASOs) that can be used as... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa; mice Citation Extract: Lessl AL, Pöhmerer J, Lin Y, Wilk U, Höhn M, Hörterer E, Wagner E, Lächelt U. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates. Bioconjug Chem. 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408. Online ahead of print. |
Induction of Reproductive Sterility in Coho Salmon (Oncorhynchus kisutch) by an Immersion-Based Gene Silencing Technology
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Citation:
J Mar Sci Eng. 2023;11:2208. doi:10.3390/jmse11122208 Epub:
Not Epub Abstract:
Undesired maturation and reproduction are major challenges in fish aquaculture regarding genetic introgression, precocious... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Oncorhynchus kisutch (coho salmon) Citation Extract: Xu L, Zhao M, Zohar Y, Wong T-T. Induction of Reproductive Sterility in Coho Salmon (Oncorhynchus kisutch) by an Immersion-Based Gene Silencing Technology. J Mar Sci Eng. 2023;11:2208. doi:10.3390/jmse11122208. |
Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer
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Citation:
Aquaculture. 2020;526:735385. doi:10.1016/j.aquaculture.2020.735385 Epub:
Not Epub Abstract:
The surrogate broodstock technique produces donor-derived gametes via transplantation of germ cells into surrogate fish. The... Delivery Method:
microinjection Organism or Cell Type:
Takifugu alboplumbeus (grass puffer) Citation Extract: Yoshikawa H, Ino Y, Kishimoto K, Koyakumaru H, Saito T, Kinoshita M, Yoshiura Y. Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer. Aquaculture. 2020;526:735385. doi:10.1016/j.aquaculture.2020.735385. |
UGT1A1 morpholino antisense oligonucleotides produce mild unconjugated hyperbilirubinemia in cyclosprin A-induced cardiovascular disorders in BLC57 mice
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Citation:
Environ Toxicol Pharmacol 2023 Nov 18:104321. doi: 10.1016/j.etap.2023.104321. Online ahead of print Epub:
Yes Abstract:
This study aimed to investigate the induction of mild unconjugated hyperbilirubinemia in hepatic UGT1A1 inhibition by... Delivery Method:
intravenous (i.v.) Organism or Cell Type:
mice Citation Extract: Marghani BH, Ateya AI, Othman BH, Rizk MA, El-Adl M. UGT1A1 morpholino antisense oligonucleotides produce mild unconjugated hyperbilirubinemia in cyclosprin A-induced cardiovascular disorders in BLC57 mice. Environ Toxicol Pharmacol 2023 Nov 18:104321. doi: 10.1016/j.etap.2023.104321. Online ahead of print. |
Embryo-scale reverse genetics at single-cell resolution
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Citation:
Nature. 2023 Nov 15. doi: 10.1038/s41586-023-06720-2. Online ahead of print Epub:
Yes Abstract:
The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saunders LM, Srivatsan SR, Duran M, Dorrity MW, Ewing B, Linbo TH, Shendure J, Raible DW, Moens CB, Kimelman D, Trapnell C. Embryo-scale reverse genetics at single-cell resolution. Nature. 2023 Nov 15. doi: 10.1038/s41586-023-06720-2. Online ahead of print. |