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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy

Authors:
Nicastro M, Vermeer Alexa MC, Postema PG,Tadros R, Bowling FZ, Aegisdottir, HM, et al.
Citation:
medRxiv [preprint] 2024.07.04.24309755
Epub:
Not Epub
Abstract:
POPDC2 encodes for the Popeye domain-containing protein 2 which has an important role in cardiac pacemaking and conduction, due...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nicastro M, Vermeer Alexa MC, Postema PG,Tadros R, Bowling FZ, Aegisdottir, HM, et al.. Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy. medRxiv [preprint] 2024.07.04.24309755.

Molecular analysis of a self-organizing signaling pathway for Xenopus axial patterning from egg to tailbud

Authors:
Azbazdar Y, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2408346121. doi: 10.1073/pnas.2408346121. Epub 2024 Jul 5. PMID: 38968117.
Epub:
Not Epub
Abstract:
Xenopus embryos provide a favorable material to dissect the sequential steps that lead to dorsal-ventral (D-V) and anterior-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Azbazdar Y, De Robertis EM. Molecular analysis of a self-organizing signaling pathway for Xenopus axial patterning from egg to tailbud. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2408346121. doi: 10.1073/pnas.2408346121. Epub 2024 Jul 5. PMID: 38968117..

Evolution and host-specific adaptation of Pseudomonas aeruginosa

Authors:
Weimann A, Dinan AM, Ruis C, Bernut A, Pont S, Brown K, Ryan J, Santos L, Ellison L, Ukor E, Pandurangan AP, Krokowski S, Blundell TL, Welch M, Blane B, Judge K, Bousfield R, Brown N, Bryant JM, Kukavica-Ibrulj I, Rampioni G, Leoni L, Harrison PT, Peacock SJ, Thomson NR, Gauthier J, Fothergill JL, Levesque RC, Parkhill J, Floto RA
Citation:
Science. 2024 Jul 5;385(6704):eadi0908. doi: 10.1126/science.adi0908. Epub 2024 Jul 5. PMID: 38963857
Epub:
Not Epub
Abstract:
The major human bacterial pathogen Pseudomonas aeruginosa causes multidrug-resistant infections in people with underlying...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weimann A, Dinan AM, Ruis C, Bernut A, Pont S, Brown K, Ryan J, Santos L, Ellison L, Ukor E, Pandurangan AP, Krokowski S, Blundell TL, Welch M, Blane B, Judge K, Bousfield R, Brown N, Bryant JM, Kukavica-Ibrulj I, Rampioni G, Leoni L, Harrison PT, Peacock SJ, Thomson NR, Gauthier J, Fothergill JL, Levesque RC, Parkhill J, Floto RA. Evolution and host-specific adaptation of Pseudomonas aeruginosa. Science. 2024 Jul 5;385(6704):eadi0908. doi: 10.1126/science.adi0908. Epub 2024 Jul 5. PMID: 38963857.

Perfluorooctane Sulfonamide Induced Autotoxic Effects on the Zebrafish Immune System

Authors:
Chen H, Zou Y, Kang X, Yang G, Yang X, Yao Y, Magnuson JT, Cao X, Qiu W, Xu EG, Zheng C
Citation:
Environ Sci Technol. 2024 Jul 8
Epub:
Not Epub
Abstract:
Perfluorooctane sulfonamide (PFOSA) is an immediate perfluorooctanesulfonate (PFOS) precursor (PreFOS). Previous studies have...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen H, Zou Y, Kang X, Yang G, Yang X, Yao Y, Magnuson JT, Cao X, Qiu W, Xu EG, Zheng C. Perfluorooctane Sulfonamide Induced Autotoxic Effects on the Zebrafish Immune System. Environ Sci Technol. 2024 Jul 8.

Variants of NAV3, a neuronal morphogenesis protein, cause intellectual disability, developmental delay, and microcephaly

Authors:
Ghaffar A, Akhter T, Strømme P, Misceo D, Khan A, Frengen E, Umair M, Isidor B, Cogné B, Khan AA, Bruel AL, Sorlin A, Kuentz P, Chiaverini C, Innes AM, Zech M, Baláž M, Havrankova P, Jech R, Ahmed ZM, Riazuddin S, Riazuddin S
Citation:
Commun Biol. 2024 Jul 8;7(1):831
Epub:
Not Epub
Abstract:
Microtubule associated proteins (MAPs) are widely expressed in the central nervous system, and have established roles in cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghaffar A, Akhter T, Strømme P, Misceo D, Khan A, Frengen E, Umair M, Isidor B, Cogné B, Khan AA, Bruel AL, Sorlin A, Kuentz P, Chiaverini C, Innes AM, Zech M, Baláž M, Havrankova P, Jech R, Ahmed ZM, Riazuddin S, Riazuddin S. Variants of NAV3, a neuronal morphogenesis protein, cause intellectual disability, developmental delay, and microcephaly. Commun Biol. 2024 Jul 8;7(1):831.

The intracellular domain of Sema6A is essential for development of the zebrafish retina

Authors:
Dumas CM, St. Clair RM, Lasseigne AM, Ballif BA, Ebert AM
Citation:
J Cell Sci jcs.261469
Epub:
Not Epub
Abstract:
Semaphorin6A (Sema6A) is a repulsive guidance molecule that plays many roles in central nervous system, heart, and bone...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dumas CM, St. Clair RM, Lasseigne AM, Ballif BA, Ebert AM. The intracellular domain of Sema6A is essential for development of the zebrafish retina. J Cell Sci jcs.261469.

Oxysterol-binding protein like 7 deficiency leads to ER stress mediated apoptosis in podocytes and proteinuria

Authors:
Duara J, Torres MF, Gurumani M, Molina David J, Njeim R, Kim JJ, Mitrofanova A, Ge M, Sloan AJ, Müller-Deile J, Schiffer M, Merscher S, Fornoni A
Citation:
Am J Physiol Renal Physiol. 2024 Jul 4
Epub:
Not Epub
Abstract:
Chronic kidney disease (CKD) is associated with renal lipid dysmetabolism among a variety of other pathways. We recently...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Duara J, Torres MF, Gurumani M, Molina David J, Njeim R, Kim JJ, Mitrofanova A, Ge M, Sloan AJ, Müller-Deile J, Schiffer M, Merscher S, Fornoni A. Oxysterol-binding protein like 7 deficiency leads to ER stress mediated apoptosis in podocytes and proteinuria. Am J Physiol Renal Physiol. 2024 Jul 4.

Reversion induced LIM domain protein (RIL) is a Daam1-interacting protein and regulator of the actin cytoskeleton during non-canonical Wnt signaling

Authors:
Mezzacappa C, Komiya Y, Habas R
Citation:
Developmental Biology. 2024 July 03
Epub:
Not Epub
Abstract:
The Daam1 protein regulates Wnt-induced cytoskeletal changes during vertebrate gastrulation though its full mode of action and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mezzacappa C, Komiya Y, Habas R. Reversion induced LIM domain protein (RIL) is a Daam1-interacting protein and regulator of the actin cytoskeleton during non-canonical Wnt signaling. Developmental Biology. 2024 July 03.

Fbxo28 is essential for spindle migration and morphology during mouse oocyte meiosis I

Authors:
Chang H, Huang C, Cheng S, Li J, Wang X
Citation:
International Journal of Biological Macromolecules. 2024 July 01
Epub:
Not Epub
Abstract:
Spindle migration and assembly regulates asymmetric oocyte division, which is essential for fertility. Fbxo28, as a member of...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Chang H, Huang C, Cheng S, Li J, Wang X. Fbxo28 is essential for spindle migration and morphology during mouse oocyte meiosis I. International Journal of Biological Macromolecules. 2024 July 01.

Primary cilia formation requires the Leigh syndrome–associated mitochondrial protein NDUFAF2

Authors:
Lo CH, Liu Z, Chen S, Lin F, Berneshawi AR, Yu CQ, Koo EB, Kowal TJ, Ning K, Hu Y, Wang WJ, Liao YJ, Sun Y
Citation:
J Clin Invest. 2024;134(13):e175560
Epub:
Not Epub
Abstract:
Mitochondria-related neurodegenerative diseases have been implicated in the disruption of primary cilia function. Mutation in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lo CH, Liu Z, Chen S, Lin F, Berneshawi AR, Yu CQ, Koo EB, Kowal TJ, Ning K, Hu Y, Wang WJ, Liao YJ, Sun Y. Primary cilia formation requires the Leigh syndrome–associated mitochondrial protein NDUFAF2. J Clin Invest. 2024;134(13):e175560.

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