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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12236 scientific papers returned from the database with the search filters currently being used below.

The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy

Authors:
Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Marchant J, Romero MR, Diop S, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K
Citation:
Cell Rep. 2024 Aug 27;43(8):114549. doi: 10.1016/j.celrep.2024.114549. Epub 2024 Aug 1. PMID: 39093699; PMCID: PMC11402474
Epub:
Not Epub
Abstract:
CREB-regulated transcription co-activator (CRTC) is activated by Calcineurin (CaN) to regulate gluconeogenic genes. CaN also...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11402474/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Marchant J, Romero MR, Diop S, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K. The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy. Cell Rep. 2024 Aug 27;43(8):114549. doi: 10.1016/j.celrep.2024.114549. Epub 2024 Aug 1. PMID: 39093699; PMCID: PMC11402474.

The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish

Authors:
Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F
Citation:
Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. PMID: 39217144; PMCID: PMC11366026
Epub:
Not Epub
Abstract:
The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been strongly debated. Here, we provide evidence...
Link:
https://www.nature.com/articles/s41467-024-51920-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F. The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish. Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. PMID: 39217144; PMCID: PMC11366026.

Sodium thiosulfate treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating nitric oxide signalling

Authors:
Ott H, Bennewitz K, Zhang X, Prianichnikova M, Sticht C, Poschet G, Kroll J
Citation:
J Physiol. 2024 Sep 12. doi: 10.1113/JP286398. Epub ahead of print. PMID: 39264236
Epub:
Not Epub
Abstract:
Sodium thiosulfate (STS) is gaining increasing attention in research for its potential therapeutic applications across a...
Link:
https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP286398
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ott H, Bennewitz K, Zhang X, Prianichnikova M, Sticht C, Poschet G, Kroll J. Sodium thiosulfate treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating nitric oxide signalling. J Physiol. 2024 Sep 12. doi: 10.1113/JP286398. Epub ahead of print. PMID: 39264236.

Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells

Authors:
Pessoa Rodrigues C, Collins JM, Yang S, Martinez C, Kim JW, Lama C, Nam AS, Alt C, Lin C, Zon LI
Citation:
Science. 2024 Sep 13;385(6714):eadn1629. doi: 10.1126/science.adn1629. Epub 2024 Sep 13. PMID: 39264994
Epub:
Not Epub
Abstract:
Macrophages maintain hematopoietic stem cell (HSC) quality by assessing cell surface Calreticulin (Calr), an "eat-me...
Link:
https://www.science.org/doi/10.1126/science.adn1629
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pessoa Rodrigues C, Collins JM, Yang S, Martinez C, Kim JW, Lama C, Nam AS, Alt C, Lin C, Zon LI. Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells. Science. 2024 Sep 13;385(6714):eadn1629. doi: 10.1126/science.adn1629. Epub 2024 Sep 13. PMID: 39264994.

Apoptotic extracellular vesicles carrying Mif regulate macrophage recruitment and compensatory proliferation in neighboring epithelial stem cells during tissue maintenance

Authors:
Essien SA, Ahuja I, Eisenhoffer GT
Citation:
PLoS Biol. 2024 Nov 4;22(11):e3002194. doi: 10.1371/journal.pbio.3002194. Epub ahead of print. PMID: 39495793
Epub:
Not Epub
Abstract:
Apoptotic cells can signal to neighboring cells to stimulate proliferation and compensate for cell loss to maintain tissue...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002194
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Essien SA, Ahuja I, Eisenhoffer GT. Apoptotic extracellular vesicles carrying Mif regulate macrophage recruitment and compensatory proliferation in neighboring epithelial stem cells during tissue maintenance. PLoS Biol. 2024 Nov 4;22(11):e3002194. doi: 10.1371/journal.pbio.3002194. Epub ahead of print. PMID: 39495793.

Tetracycline and Oxacillin Act Synergistically on Biofilms and Display Increased Efficacy In Vivo Against Staphylococcus aureus

Authors:
Tooke AK, Hodges RE, Pyrah JF, Bayles KW, Renshaw SA, Foster SJ
Citation:
Curr Microbiol. 2024 Nov 6;81(12):447. doi: 10.1007/s00284-024-03959-4. PMID: 39505760; PMCID: PMC11541413
Epub:
Not Epub
Abstract:
Oxacillin (bactericidal) and tetracycline (bacteriostatic) are clinically relevant antibiotics that are routinely prescribed to...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11541413/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tooke AK, Hodges RE, Pyrah JF, Bayles KW, Renshaw SA, Foster SJ. Tetracycline and Oxacillin Act Synergistically on Biofilms and Display Increased Efficacy In Vivo Against Staphylococcus aureus. Curr Microbiol. 2024 Nov 6;81(12):447. doi: 10.1007/s00284-024-03959-4. PMID: 39505760; PMCID: PMC11541413.

Evaluating the involvement and mutual interaction of wbp2 and yap in embryogenesis with an emphasis on liver function in zebrafish embryos

Authors:
Lykov N, Wang H, Panga MJ, Du Z, Chen Z, Chen S, Zhu L, Zhao Y
Citation:
Tissue Cell. 2024 Oct 29;91:102600. doi: 10.1016/j.tice.2024.102600. Epub ahead of print. PMID: 39486132
Epub:
Not Epub
Abstract:
The Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) play complex roles in liver...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S004081662400301X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lykov N, Wang H, Panga MJ, Du Z, Chen Z, Chen S, Zhu L, Zhao Y. Evaluating the involvement and mutual interaction of wbp2 and yap in embryogenesis with an emphasis on liver function in zebrafish embryos. Tissue Cell. 2024 Oct 29;91:102600. doi: 10.1016/j.tice.2024.102600. Epub ahead of print. PMID: 39486132.

Planar cell polarity zebrafish models of congenital scoliosis reveal underlying defects in notochord morphogenesis

Authors:
Wang M, Zhao S, Shi C, Guyot MC, Liao M, Tauer JT, Willie BM, Cobetto N, Aubin CÉ, Küster-Schöck E, Drapeau P, Zhang J, Wu N, Kibar Z
Citation:
Development. 2024 Nov 1;151(21):dev202829. doi: 10.1242/dev.202829. Epub 2024 Nov 12. PMID: 39417583
Epub:
Not Epub
Abstract:
Congenital scoliosis (CS) is a type of vertebral malformation whose etiology remains elusive. The notochord is pivotal for...
Link:
https://journals.biologists.com/dev/article-abstract/151/21/dev202829/362927/Planar-cell-polarity-zebrafish-models-of
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang M, Zhao S, Shi C, Guyot MC, Liao M, Tauer JT, Willie BM, Cobetto N, Aubin CÉ, Küster-Schöck E, Drapeau P, Zhang J, Wu N, Kibar Z. Planar cell polarity zebrafish models of congenital scoliosis reveal underlying defects in notochord morphogenesis. Development. 2024 Nov 1;151(21):dev202829. doi: 10.1242/dev.202829. Epub 2024 Nov 12. PMID: 39417583.

Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations

Authors:
Pham VC, Rödel CJ, Valentino M, Malinverno M, Paolini A, Münch J, Pasquier C, Onyeogaziri FC, Lazovic B, Girard R, Koskimäki J, Hußmann M, Keith B, Jachimowicz D, Kohl F, Hagelkruys A, Penninger JM, Schulte-Merker S, Awad IA, Hicks R, Magnusson PU, Faurobert E, Pagani M, Abdelilah-Seyfried S
Citation:
EMBO Mol Med. 2024 Nov;16(11):2827-2855. doi: 10.1038/s44321-024-00152-9. Epub 2024 Oct 14. PMID: 39402138; PMCID: PMC11555420
Epub:
Not Epub
Abstract:
Cerebral cavernous malformations (CCMs) are anomalies of the cerebral vasculature. Loss of the CCM proteins CCM1/KRIT1, CCM2,...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11555420/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pham VC, Rödel CJ, Valentino M, Malinverno M, Paolini A, Münch J, Pasquier C, Onyeogaziri FC, Lazovic B, Girard R, Koskimäki J, Hußmann M, Keith B, Jachimowicz D, Kohl F, Hagelkruys A, Penninger JM, Schulte-Merker S, Awad IA, Hicks R, Magnusson PU, Faurobert E, Pagani M, Abdelilah-Seyfried S. Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations. EMBO Mol Med. 2024 Nov;16(11):2827-2855. doi: 10.1038/s44321-024-00152-9. Epub 2024 Oct 14. PMID: 39402138; PMCID: PMC11555420.

Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms

Authors:
Bowden S, Brislinger-Engelhardt MM, Hansen M, Temporal-Plo A, Weber D, Hägele S, Lorenz F, Litwin T, Kreutz C, Walentek P
Citation:
bioRxiv [Preprint]. 2024 Nov 4:2024.10.27.620464. doi: 10.1101/2024.10.27.620464. PMID: 39484493; PMCID: PMC11527170
Epub:
Not Epub
Abstract:
Foxi1 is a master regulator of ionocytes (ISCs / INCs) across species and organs. Two subtypes of ISCs exist, and both α- and...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11527170/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bowden S, Brislinger-Engelhardt MM, Hansen M, Temporal-Plo A, Weber D, Hägele S, Lorenz F, Litwin T, Kreutz C, Walentek P. Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms. bioRxiv [Preprint]. 2024 Nov 4:2024.10.27.620464. doi: 10.1101/2024.10.27.620464. PMID: 39484493; PMCID: PMC11527170.

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