You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12533 scientific papers returned from the database with the search filters currently being used below.
There are 12533 scientific papers returned from the database with the search filters currently being used below.
NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency on NF2-SWN iPSC-derived spheroid model
|
Citation:
bioRxiv 2025.11.14.688164; doi: https://doi.org/10.1101/2025.11.14.688164 Epub:
Not Epub Abstract:
NF2-related Schwannomatosis (NF2-SWN) is an inherited autosomal dominant disorder resulting from loss-of-function mutations in... Delivery Method:
Endo-Porter for iPSCs differentiated into neural crest (NC) spheroids, Vivo-Morpholino for Schwann cell spheroids differentiated from NC cells Organism or Cell Type:
NF2-SWN patient-derived primary fibroblasts Citation Extract: Casals-Sendra G, Jarne-Sanz I, Catasús N, Boluda-Luis I, Quer A, Amilibia E, Lázaro C, Serra E, Blanco I, Castellanos E. NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency on NF2-SWN iPSC-derived spheroid model. bioRxiv 2025.11.14.688164; doi: https://doi.org/10.1101/2025.11.14.688164. |
Zebrafish col4a1 loss-of-function models mirror key neurovascular and ocular features of COL4A1/A2 syndrome and enable human variants assessment in vivo
|
Citation:
Matrix Biol. 2025 Nov 15:S0945-053X(25)00108-8. doi: 10.1016/j.matbio.2025.11.004. Epub ahead of print. PMID: 41248836 Epub:
Not Epub Abstract:
Pathogenic variants in COL4A1 and COL4A2, encoding type IV collagen α1 and α2 chains-core components of all basement membranes-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paradisi G, Bonavolontà V, Venditti M, Fasano G, Pedalino C, Bene FD, Tartaglia M, Lauri A. Zebrafish col4a1 loss-of-function models mirror key neurovascular and ocular features of COL4A1/A2 syndrome and enable human variants assessment in vivo. Matrix Biol. 2025 Nov 15:S0945-053X(25)00108-8. doi: 10.1016/j.matbio.2025.11.004. Epub ahead of print. PMID: 41248836. |
Sox8 is essential for vertebrate gastrulation
|
Citation:
EMBO Rep. 2025 Nov 10. doi: 10.1038/s44319-025-00617-z. Epub ahead of print. PMID: 41214364 Epub:
Not Epub Abstract:
Gastrulation is a fundamental developmental process during which germ layers are formed and the body axes are defined by the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Moreira S, Korovesi AG, Barriga EH. Sox8 is essential for vertebrate gastrulation. EMBO Rep. 2025 Nov 10. doi: 10.1038/s44319-025-00617-z. Epub ahead of print. PMID: 41214364. |
CANTAC-seq analysis reveals E2f1 and Otx1 coordinate zygotic genome activation in Xenopus tropicalis
|
Citation:
Nat Commun. 2025 Nov 18;16(1):10101. doi: 10.1038/s41467-025-65146-8. PMID: 41253814 Epub:
Not Epub Abstract:
Zygotic genome activation is tightly associated with the modulation of chromatin accessibility via maternal transcription... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Cui H, Liang W, Shi Z, Zhang L, Li G, Chen R, Tian C, Gan D, Shi X, Sun Z, Zhu Q, Fang L, Huang H, Hu Y, Chen Y, Chen W. CANTAC-seq analysis reveals E2f1 and Otx1 coordinate zygotic genome activation in Xenopus tropicalis. Nat Commun. 2025 Nov 18;16(1):10101. doi: 10.1038/s41467-025-65146-8. PMID: 41253814. |
Mechanochemical mechanism underlying intercellular Ca2+ wave propagation and its crucial role in apoptotic cell extrusion
|
Citation:
Nat Commun. 2025 Nov 17;16(1):9887. doi: 10.1038/s41467-025-65474-9. PMID: 41249134; PMCID: PMC12623941 Epub:
Not Epub Abstract:
Calcium (Ca2+) wave propagation plays a crucial role in intercellular communication. Elevation of cytosolic Ca2+ (Ca2+... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yamada S, Yasukuni R, Bessho Y, Fujita Y, Hosokawa Y, Matsui T. Mechanochemical mechanism underlying intercellular Ca2+ wave propagation and its crucial role in apoptotic cell extrusion. Nat Commun. 2025 Nov 17;16(1):9887. doi: 10.1038/s41467-025-65474-9. PMID: 41249134; PMCID: PMC12623941. |
Systematic mapping of small nucleolar rna interactions in human cells
|
Citation:
RNA Biol. 2025 Nov 14. doi: 10.1080/15476286.2025.2589573. Epub ahead of print. PMID: 41236713 Epub:
Not Epub Abstract:
Altered expression of box C/D small nucleolar RNAs (snoRNAs) is implicated in human diseases, including cancer. Box C/D snoRNAs... Organism or Cell Type:
HEK cells Citation Extract: Dunn-Davies H, Dudnakova T, Langhendries JL, Watkins N, Lafontaine DLJ, Tollervey D. Systematic mapping of small nucleolar rna interactions in human cells. RNA Biol. 2025 Nov 14. doi: 10.1080/15476286.2025.2589573. Epub ahead of print. PMID: 41236713. |
Proximity-based proteomics (BioID) uncovers the Rho GTPase interactome in kidney podocytes
|
Citation:
Frontiers in Cell and Developmental Biology. Volume 13 - 2025. doi 10.3389/fcell.2025.1625950 Epub:
Not Epub Abstract:
Introduction: Podocyte injury causes proteinuria. Rho GTPases play critical roles in regulating the podocyte cytoskeleton, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ibrahim S, Matsuda J, Nurcombe ZW, Boulais J, Aoudjit L, Foxman E, Kazan C, Suzuki S, Leclerc S, Shimada N, Kitzler T, Coté JF, Takano T. Proximity-based proteomics (BioID) uncovers the Rho GTPase interactome in kidney podocytes. Frontiers in Cell and Developmental Biology. Volume 13 - 2025. doi 10.3389/fcell.2025.1625950. |
Non-visual photoreceptive brain specification in sea urchin larvae
|
Citation:
Nat Commun. 2025 Nov 19;16(1):10054. doi: 10.1038/s41467-025-65628-9. PMID: 41258319 Epub:
Not Epub Abstract:
Centralized nervous systems enable animals to detect environmental cues and coordinate behavior, but their evolutionary origins... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Yaguchi J, Tsuyuzaki K, Sawada I, Horiuchi A, Sakamoto N, Yamamoto T, Yamashita T, Yaguchi S. Non-visual photoreceptive brain specification in sea urchin larvae. Nat Commun. 2025 Nov 19;16(1):10054. doi: 10.1038/s41467-025-65628-9. PMID: 41258319. |
Phosphorylation of YWHAZ at Serine 58 by PKB/Akt is associated with resumption of meiotic arrest in mouse oocytes
|
Citation:
Mol Hum Reprod. 2025 Nov 14:gaaf056. doi: 10.1093/molehr/gaaf056. Epub ahead of print. PMID: 41237317 Epub:
Not Epub Abstract:
Mammalian oocyte maturation is a tightly regulated process essential for successful fertilisation and embryonic development.... Organism or Cell Type:
mouse oocyte Citation Extract: Huo J, Zhao Y, Ma Z, Zheng H, Peng H. Phosphorylation of YWHAZ at Serine 58 by PKB/Akt is associated with resumption of meiotic arrest in mouse oocytes. Mol Hum Reprod. 2025 Nov 14:gaaf056. doi: 10.1093/molehr/gaaf056. Epub ahead of print. PMID: 41237317. |
Axenfeld-Rieger Syndrome: From Zebrafish Models to Clinical Outcomes
|
Citation:
Am J Ophthalmol. 2025 Nov 14:S0002-9394(25)00595-1. doi: 10.1016/j.ajo.2025.11.010. Epub ahead of print. PMID: 41242594 Epub:
Not Epub Abstract:
PURPOSE: To investigate genetics and outcomes in Axenfeld-Rieger Syndrome (ARS)
METHODS: Retrospective cohort study of ARS... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bohnsack BL, Williams AL, Jacobson A, Drackley A, Bolton E, Rossen JL. Axenfeld-Rieger Syndrome: From Zebrafish Models to Clinical Outcomes. Am J Ophthalmol. 2025 Nov 14:S0002-9394(25)00595-1. doi: 10.1016/j.ajo.2025.11.010. Epub ahead of print. PMID: 41242594. |