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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12231 scientific papers returned from the database with the search filters currently being used below.
There are 12231 scientific papers returned from the database with the search filters currently being used below.
De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance
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Citation:
Nat Commun. 2026 Aug 27;17(1):8900. doi: 10.1038/s41467-026-76710-1. PMID: 42660948; PMCID: PMC13522565 Epub:
Not Epub Abstract:
Beyond serving as cohesive barriers, epithelia clear apoptotic cells to regulate development, homeostasis and inflammation. How... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Häkkinen HM, Batet M, Bianchi LF, Jiménez-Delgado S, Pezzano F, Wieser S, Ciampa L, Hoijman E, Vibe C, Wijma S, Ruprecht V. De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance. Nat Commun. 2026 Aug 27;17(1):8900. doi: 10.1038/s41467-026-76710-1. PMID: 42660948; PMCID: PMC13522565. |
Reduced expression of human metapneumovirus matrix protein impacts virus assembly and ribonucleoprotein localization
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Citation:
J Virol. 2026 Aug 31:e0106626. doi: 10.1128/jvi.01066-26. Epub ahead of print. PMID: 42671868 Epub:
Not Epub Abstract:
Human metapneumovirus (HMPV) causes severe respiratory tract infections in all cohorts, particularly in vulnerable groups such... Delivery Method:
(RXR)4XB peptide-linked Organism or Cell Type:
A549 cells Citation Extract: Heim CJ, Stein DA, Moulton HM, Galperin E, Dutch RE. Reduced expression of human metapneumovirus matrix protein impacts virus assembly and ribonucleoprotein localization. J Virol. 2026 Aug 31:e0106626. doi: 10.1128/jvi.01066-26. Epub ahead of print. PMID: 42671868. |
Ptprz1b phosphatase binds Prickle2 to promote its membrane localization
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Citation:
iScience. 2026 Jul 13;29(8):116707 Epub:
Not Epub Abstract:
The Wnt/planar cell polarity (PCP) pathway plays a critical role in the development and homeostasis of multicellular organisms... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Le Y, Novotna S, Maia LA, Tolwinski NS, Winkler C, Harnos J. Ptprz1b phosphatase binds Prickle2 to promote its membrane localization. iScience. 2026 Jul 13;29(8):116707. |
Four new Duchenne muscular dystrophy mouse models with clinically relevant exon deletions in the human DMD gene
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Citation:
Dis Model Mech. 2026 Aug 21:dmm.052875 Epub:
Not Epub Abstract:
Mutation specific therapeutic approaches, like exon skipping or gene-editing, hold promise for the treatment of Duchenne... Delivery Method:
Vivo-Morpholino, intramuscular (i.m.) injection Organism or Cell Type:
humanized DMD mouse models with either a deletion of exon 44, 45, 51 or 53 Citation Extract: van Putten M, Linssen M, de Winter CT, Brouwers CM, Claassens JWC, Verwey N, Walsh M, Stan TL, Aartsma-Rus A, Hohenstein P. Four new Duchenne muscular dystrophy mouse models with clinically relevant exon deletions in the human DMD gene. Dis Model Mech. 2026 Aug 21:dmm.052875. |
Protocol for manipulating mRNA splicing via vivo-morpholino in early-activating muscle stem cells
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Citation:
STAR Protoc. 2026 Aug 20;7(3):104796 Epub:
Not Epub Abstract:
Muscle stem cells (MuSCs), also called satellite cells (SCs), are essential for skeletal muscle regeneration. SCs undergo rapid... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Tg:Pax7nGFP mice; muscle stem cells (MuSCs) also called satellite cells (SCs) Citation Extract: Lin K, Yin Y, Cheung TH. Protocol for manipulating mRNA splicing via vivo-morpholino in early-activating muscle stem cells. STAR Protoc. 2026 Aug 20;7(3):104796. |
Peptide-phosphorodiamidate morpholino oligomer therapy for dysferlinopathy induces pseudoexon skipping and restoration of functional protein
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Citation:
JCI Insight. 2026 Jul 14;11(16):e204742 Epub:
Not Epub Abstract:
The dysferlinopathies are a spectrum of autosomal recessive muscle diseases caused by mutations in the dysferlin gene (DYSF).... Delivery Method:
Endo-Porter for myotubes, Pip9b2 peptide-linked for mice, DNA-RNA hybrids with cholesterol conjugated to a nucleic acid strand that is complementary to PMO for mice; intravenous (i.v.) for mice Organism or Cell Type:
patient-derived myotubes; PE44.1 mice Citation Extract: Gooding JE, Park G, Wagh A, Watts JK, Dominov JA, Brown RH Jr. Peptide-phosphorodiamidate morpholino oligomer therapy for dysferlinopathy induces pseudoexon skipping and restoration of functional protein. JCI Insight. 2026 Jul 14;11(16):e204742. |
Sunitinib induces macrophage dysfunction and impaired tissue regeneration through suppression of PPARγ
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Citation:
Front. Immunol. (2026) 17:1900449. doi: 10.3389/fimmu.2026.1900449 Epub:
Not Epub Abstract:
Background: Sunitinib is a widely used multi-target tyrosine kinase inhibitor associated with side effects that may impair... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Z, Qiao Q, Li J, Li Q, Yang Y, Zhou Y, Huang H, Chen D, Wang Y and Guo Y. Sunitinib induces macrophage dysfunction and impaired tissue regeneration through suppression of PPARγ. Front. Immunol. (2026) 17:1900449. doi: 10.3389/fimmu.2026.1900449. |
An antisense method for efficient exon skipping and its application to Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2026 Aug 18;123(33):e2606494123 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping has been used to treat Duchenne muscular dystrophy (DMD) by restoring the DMD reading frame to... Delivery Method:
intravenous (i.v.) infusion for monkeys and injection for mice, no transfection for cells Organism or Cell Type:
huΔ52 (exon 52 deleted) mice, cynomolgus monkeys; rhabdomyosarcoma (RD) cells Citation Extract: Feng P, Gao P, Meng S, Yuan Y, Krainer AR, Hua Y. An antisense method for efficient exon skipping and its application to Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2026 Aug 18;123(33):e2606494123. |
Znf131 is required for gastrulation and neurulation in early Xenopus development
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Citation:
Differentiation. 2026 Aug 17:100989 Epub:
Not Epub Abstract:
Early vertebrate development involves several highly orchestrated morphogenic movements. Two key movements are gastrulation,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Knapp J, Cowan RW, Mersereau J, Park JI, Mohammadi D, McCrea PD, Marsden M, Daniel JM. Znf131 is required for gastrulation and neurulation in early Xenopus development. Differentiation. 2026 Aug 17:100989. |
Facile Siderophore Assembly Enables Bacterial Delivery of Nucleic Acid Therapeutics
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Citation:
ACS Chem Biol. 2026 Aug 19 Epub:
Not Epub Abstract:
Antibiotic resistance is an increasing threat to modern medicine that calls for the discovery of new antibiotics. RNA targeting... Delivery Method:
PMO-siderophore conjugate Organism or Cell Type:
E. coli Citation Extract: Ramu H, Kuijken P, Poulladofonou G, Pals MJ, Summerton D, Li YF, Velema WA. Facile Siderophore Assembly Enables Bacterial Delivery of Nucleic Acid Therapeutics. ACS Chem Biol. 2026 Aug 19. |