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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12160 scientific papers returned from the database with the search filters currently being used below.

A simple and highly sensitive LC-MS/MS bioanalytical method for phosphorodiamidate morpholino oligonucleotides in plasma

Authors:
Kameyama T, Imai S, Mitamura R, Niwa M, Yamada T, Kusano K
Citation:
Bioanalysis. 2026 Feb 19:1-13. doi: 10.1080/17576180.2026.2632688. Epub ahead of print. PMID: 41711019
Epub:
Not Epub
Abstract:
Background: LC-MS/MS is widely used for the quantification of phosphorodiamidate morpholino oligomers, but its low sensitivity...
Link:
https://www.tandfonline.com/doi/full/10.1080/17576180.2026.2632688
Organism or Cell Type:
PMO-spiked rat and human plasma
Citation Extract:
Kameyama T, Imai S, Mitamura R, Niwa M, Yamada T, Kusano K. A simple and highly sensitive LC-MS/MS bioanalytical method for phosphorodiamidate morpholino oligonucleotides in plasma. Bioanalysis. 2026 Feb 19:1-13. doi: 10.1080/17576180.2026.2632688. Epub ahead of print. PMID: 41711019.

A Suspended Graphene Field-Effect Transistor for Ultra-Sensitive and Label-Free Detection of Cancer Biomarker miR-21

Authors:
Deng Z, Zeng C, Wu Q, Zhang F, Zhuang P
Citation:
Biosensors. 2026; 16(2):125. https://doi.org/10.3390/bios16020125
Epub:
Not Epub
Abstract:
The sensitive detection of microRNA-21 (miR-21), a key biomarker for various cancers, is crucial for early diagnosis, yet...
Link:
https://www.mdpi.com/2079-6374/16/2/125
Delivery Method:
PMO probe to capture synthetic miR-21
Citation Extract:
Deng Z, Zeng C, Wu Q, Zhang F, Zhuang P. A Suspended Graphene Field-Effect Transistor for Ultra-Sensitive and Label-Free Detection of Cancer Biomarker miR-21. Biosensors. 2026; 16(2):125. https://doi.org/10.3390/bios16020125.

Insulin-like growth factor signaling regulates zebrafish lymphatic-vessel development

Authors:
Chen W, Misa JP, Herbert CD, Watkin B, Stevenson TJ, McCullough SJC, Lee KL, Bohlander SK, Hoyle DJ, Crosier PS, Schilling TF, Rustenhoven J, Hall CJ, Astin JW
Citation:
Cell Rep. 2026 Feb 13;45(2):116971. doi: 10.1016/j.celrep.2026.116971. Epub ahead of print. PMID: 41691624
Epub:
Not Epub
Abstract:
The coordinated migration of lymphatic endothelial cells (LECs) is essential for the development of the lymphatic network. Here...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00049-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen W, Misa JP, Herbert CD, Watkin B, Stevenson TJ, McCullough SJC, Lee KL, Bohlander SK, Hoyle DJ, Crosier PS, Schilling TF, Rustenhoven J, Hall CJ, Astin JW. Insulin-like growth factor signaling regulates zebrafish lymphatic-vessel development. Cell Rep. 2026 Feb 13;45(2):116971. doi: 10.1016/j.celrep.2026.116971. Epub ahead of print. PMID: 41691624.

Targeted blocking of gene splicing can dysregulate intron-embedded primary microRNAs

Authors:
Ali MH, Ramesh AR, Nedunchezhian N, Kwiatkowski W, Kopeć P, Kowalewska N, Pęcherz S, Gnutti B, Finazzi D, Anbalagan S
Citation:
Commun Biol. 2026 Feb 16;9(1):252. doi: 10.1038/s42003-026-09529-7. PMID: 41699380; PMCID: PMC12910030
Epub:
Not Epub
Abstract:
Addressing whether antisense oligonucleotides (ASOs)-based targeting of genes embedded with intronic noncoding RNAs (ncRNAs)...
Link:
https://www.nature.com/articles/s42003-026-09529-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ali MH, Ramesh AR, Nedunchezhian N, Kwiatkowski W, Kopeć P, Kowalewska N, Pęcherz S, Gnutti B, Finazzi D, Anbalagan S. Targeted blocking of gene splicing can dysregulate intron-embedded primary microRNAs. Commun Biol. 2026 Feb 16;9(1):252. doi: 10.1038/s42003-026-09529-7. PMID: 41699380; PMCID: PMC12910030.

Spatiotemporal coordination of Slit-Robo repulsion and neurturin-Gfrα attraction guides multipolar migration during retinal lamination

Authors:
Lehtimäki JI, Lilue J, Cruz MR, Del Rosario M, Nerli E, Henriques R, Norden C
Citation:
Cell Rep. 2026 Feb 3;45(2):116948. doi: 10.1016/j.celrep.2026.116948. Epub ahead of print. PMID: 41642709
Epub:
Not Epub
Abstract:
Multipolar migration is a conserved neuronal migration mode in the developing brain, enabling emerging neurons to navigate in...
Link:
https://www.sciencedirect.com/science/article/pii/S2211124726000264
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lehtimäki JI, Lilue J, Cruz MR, Del Rosario M, Nerli E, Henriques R, Norden C. Spatiotemporal coordination of Slit-Robo repulsion and neurturin-Gfrα attraction guides multipolar migration during retinal lamination. Cell Rep. 2026 Feb 3;45(2):116948. doi: 10.1016/j.celrep.2026.116948. Epub ahead of print. PMID: 41642709.

Planar polarization of endogenous ADIP during Xenopus neurulation

Authors:
Santhi Velayudhan S, Itoh K, Chu CW, Alfandari D, Sokol SY
Citation:
Biol Open. 2026 Feb 15;15(2):bio062452. doi: 10.1242/bio.062452. Epub 2026 Feb 6. PMID: 41601266
Epub:
Not Epub
Abstract:
Coordinated cell polarity and force-responsive protein localization are essential for tissue morphogenesis, yet how embryonic...
Link:
https://journals.biologists.com/bio/article/15/2/bio062452/370608/Planar-polarization-of-endogenous-ADIP-during
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Santhi Velayudhan S, Itoh K, Chu CW, Alfandari D, Sokol SY. Planar polarization of endogenous ADIP during Xenopus neurulation. Biol Open. 2026 Feb 15;15(2):bio062452. doi: 10.1242/bio.062452. Epub 2026 Feb 6. PMID: 41601266.

Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe

Authors:
Ristori T, Thuret R, Hooker E, Quicke P, Sanlidag S, Lanthier K, Ntumba K, Aspalter IM, Uroz M, Sahlgren CM, Herbert SP, Chen CS, Larrivée B, Bentley K
Citation:
Dev Cell. 2026 Feb 5:S1534-5807(26)00029-8. doi: 10.1016/j.devcel.2026.01.006. Epub ahead of print. PMID: 41650956
Epub:
Not Epub
Abstract:
Sprouting angiogenesis and blood vessel stabilization require precise coordination between endothelial cells (ECs) and...
Link:
https://www.cell.com/developmental-cell/fulltext/S1534-5807(26)00029-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ristori T, Thuret R, Hooker E, Quicke P, Sanlidag S, Lanthier K, Ntumba K, Aspalter IM, Uroz M, Sahlgren CM, Herbert SP, Chen CS, Larrivée B, Bentley K. Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe. Dev Cell. 2026 Feb 5:S1534-5807(26)00029-8. doi: 10.1016/j.devcel.2026.01.006. Epub ahead of print. PMID: 41650956.

Development of a zebrafish model of Loeys-Dietz syndrome through tgfbr2b knockdown

Authors:
Chida R, Kawahara G, Nakayashiki M, Kawashima H, Yamanaka G, Hayashi YK
Citation:
J Hum Genet. 2026 Feb 3. doi: 10.1038/s10038-026-01457-y. Epub ahead of print. PMID: 41629640
Epub:
Not Epub
Abstract:
Loeys-Dietz syndrome (LDS), an autosomal dominant connective tissue disorder, was initially considered "atypical"...
Link:
https://www.nature.com/articles/s10038-026-01457-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chida R, Kawahara G, Nakayashiki M, Kawashima H, Yamanaka G, Hayashi YK. Development of a zebrafish model of Loeys-Dietz syndrome through tgfbr2b knockdown. J Hum Genet. 2026 Feb 3. doi: 10.1038/s10038-026-01457-y. Epub ahead of print. PMID: 41629640.

Robust cytoplasmic partitioning by solving a cytoskeletal instability

Authors:
Rinaldin M, Kickuth A, Lamson A, Dalton B, Xu Y, Mejstřík P, Di Talia S, Brugués J
Citation:
Nature. 2026 Jan 28. doi: 10.1038/s41586-025-10023-z. Epub ahead of print. PMID: 41606324
Epub:
Not Epub
Abstract:
Early development across vertebrates and insects critically relies on robustly reorganizing the cytoplasm of fertilized eggs...
Link:
https://www.nature.com/articles/s41586-025-10023-z
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rinaldin M, Kickuth A, Lamson A, Dalton B, Xu Y, Mejstřík P, Di Talia S, Brugués J. Robust cytoplasmic partitioning by solving a cytoskeletal instability. Nature. 2026 Jan 28. doi: 10.1038/s41586-025-10023-z. Epub ahead of print. PMID: 41606324.

Estrogen produced in the retina by brain aromatase plays a significant role in zebrafish eye development

Authors:
Ulhaq ZS, Kishida M
Citation:
Biochim Biophys Acta Gene Regul Mech. 2025 Dec 15;1869(1):195133. doi: 10.1016/j.bbagrm.2025.195133. Epub ahead of print. PMID: 41407153
Epub:
Not Epub
Abstract:
Aromatase is a key enzyme in estrogen biosynthesis, expressed in multiple tissues including the brain and retina. In teleost...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1874939925000586
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ulhaq ZS, Kishida M. Estrogen produced in the retina by brain aromatase plays a significant role in zebrafish eye development. Biochim Biophys Acta Gene Regul Mech. 2025 Dec 15;1869(1):195133. doi: 10.1016/j.bbagrm.2025.195133. Epub ahead of print. PMID: 41407153.

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