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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is mis-spliced in striated muscle diseases
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Citation:
RNA Biol. 2025 Apr 10. doi: 10.1080/15476286.2025.2491160. Epub ahead of print. PMID: 40207498 Epub:
Not Epub Abstract:
The reprogramming of alternative splicing networks during development is a hallmark of tissue maturation and identity.... Delivery Method:
electroporation Organism or Cell Type:
C2C12 myoblast cells Citation Extract: Gentile GM, Blue RE, Goda GA, Guzman BB, Szymanski RA, Lee EY, Engels NM, Hinkle ER, Wiedner HJ, Bishop AN, Harrison JT, Zhang H, Wehrens XHT, Dominguez D, Giudice J. Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is mis-spliced in striated muscle diseases. RNA Biol. 2025 Apr 10. doi: 10.1080/15476286.2025.2491160. Epub ahead of print. PMID: 40207498. |
Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy
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Citation:
PLoS Biol. 2025 Apr 10;23(4):e3002499. doi: 10.1371/journal.pbio.3002499. Epub ahead of print. PMID: 40208862 Epub:
Not Epub Abstract:
SLC13A5 encodes a citrate transporter highly expressed in the brain and is important for regulating intra- and extracellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dogra D, Phan VA, Zhang S, Gavrilovici C, DiMarzo N, Narang A, Ibhazehiebo K, Kurrasch DM. Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy. PLoS Biol. 2025 Apr 10;23(4):e3002499. doi: 10.1371/journal.pbio.3002499. Epub ahead of print. PMID: 40208862. |
Pulmonary mitochondrial DNA release and activation of the cGAS-STING pathway in Lethal Stx12 knockout mice
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Citation:
Cell Commun Signal. 2025 Apr 8;23(1):174. doi: 10.1186/s12964-025-02141-y. PMID: 40200300; PMCID: PMC11980072 Epub:
Not Epub Abstract:
STX12 (syntaxin12 or syntaxin13), a member of the SNARE protein family, plays a crucial role in intracellular vesicle transport... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu DH, Li F, Yang RZ, Wu Z, Meng XY, Li SM, Li WX, Li JK, Wang DD, Wang RY, Li SA, Liu PP, Kang JS. Pulmonary mitochondrial DNA release and activation of the cGAS-STING pathway in Lethal Stx12 knockout mice. Cell Commun Signal. 2025 Apr 8;23(1):174. doi: 10.1186/s12964-025-02141-y. PMID: 40200300; PMCID: PMC11980072. |
Conception and synthesis of sequence-coded morpholinos
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Citation:
Chemistry. 2025 Apr 14:e202501161. doi: 10.1002/chem.202501161. Epub ahead of print. PMID: 40227092 Epub:
Not Epub Abstract:
Solid-phase morpholino chemistry was explored as a new route to synthesize abiological sequence-defined oligomers. Two... Delivery Method:
None Organism or Cell Type:
None Citation Extract: Pousse B, Al Ouahabi A, Baxter PNW, Charles L, Lutz JF. Conception and synthesis of sequence-coded morpholinos. Chemistry. 2025 Apr 14:e202501161. doi: 10.1002/chem.202501161. Epub ahead of print. PMID: 40227092. |
The cohesin-associated protein Pds5A governs the meiotic spindle assembly via deubiquitination of Kif5B in oocytes
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Citation:
Sci Adv. 2025 Apr 11;11(15):eadt6159. doi: 10.1126/sciadv.adt6159. Epub 2025 Apr 11. PMID: 40215310; PMCID: PMC11988415 Epub:
Not Epub Abstract:
Chromosome cohesion mediated by cohesin complex and its associated proteins is required for accurate chromosome segregation and... Delivery Method:
microinjection Organism or Cell Type:
ICR mouse oocyst Citation Extract: Zhang Y, Bai J, Xiong B. The cohesin-associated protein Pds5A governs the meiotic spindle assembly via deubiquitination of Kif5B in oocytes. Sci Adv. 2025 Apr 11;11(15):eadt6159. doi: 10.1126/sciadv.adt6159. Epub 2025 Apr 11. PMID: 40215310; PMCID: PMC11988415. |
Far-red fluorescent genetically encoded calcium ion indicators
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Citation:
Nat Commun. 2025 Apr 7;16(1):3318. doi: 10.1038/s41467-025-58485-z. PMID: 40195305 Epub:
Not Epub Abstract:
Genetically encoded calcium ion (Ca2+) indicators (GECIs) are widely-used molecular tools for functional imaging of Ca2+... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dalangin R, Jia BZ, Qi Y, Aggarwal A, Sakoi K, Drobizhev M, Molina RS, Patel R, Abdelfattah AS, Zheng J, Reep D, Hasseman JP; GENIE Project Team; Zhao Y, Wu J, Podgorski K, Tebo AG, Schreiter ER, Hughes TE, Terai T, Paquet ME, Megason SG, Cohen AE, Shen Y, Campbell RE. Far-red fluorescent genetically encoded calcium ion indicators. Nat Commun. 2025 Apr 7;16(1):3318. doi: 10.1038/s41467-025-58485-z. PMID: 40195305. |
Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis
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Citation:
Biomed Pharmacother. 2025 Mar 31;186:117957. doi: 10.1016/j.biopha.2025.117957. Epub ahead of print. PMID: 40168724 Epub:
Not Epub Abstract:
Background: Overactive neutrophilic inflammation causes damage to the airways and death in people with cystic fibrosis (CF), a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Leon-Icaza SA, Frétaud M, Cornélie S, Bureau C, Yatime L, Floto RA, Renshaw SA, Herrmann JL, Langevin C, Cougoule C, Bernut A. Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis. Biomed Pharmacother. 2025 Mar 31;186:117957. doi: 10.1016/j.biopha.2025.117957. Epub ahead of print. PMID: 40168724. |
Probe-Screened Carbon Nanotube Field-Effect Transistor Biosensor to Enhance Breast Cancer-Related Gene Assay
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Citation:
Green Analytical Chemistry (2025) 100267, ISSN 2772-5774, doi.org/10.1016/j.greeac.2025.100267 Epub:
Not Epub Abstract:
BRCA1 gene testing is a trump card for liquid biopsy and early diagnosis in breast cancer, which has been limited, however, by... Delivery Method:
None Organism or Cell Type:
DNA samples extracted from BRCA1-mutated breast cancer patients and healthy controls Citation Extract: Liu P, Liu Y, Cai B, Li J, Zhang G-J. Probe-Screened Carbon Nanotube Field-Effect Transistor Biosensor to Enhance Breast Cancer-Related Gene Assay. Green Analytical Chemistry (2025) 100267, ISSN 2772-5774, doi.org/10.1016/j.greeac.2025.100267. |
Evi1 is necessary for late activation of delta-notch signaling in sea urchin embryos
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Citation:
bioRxiv [preprint] 2025.04.01.646662; doi: https://doi.org/10.1101/2025.04.01.646662 Epub:
Not Epub Abstract:
Embryonic mesoderm specification and differentiation rely on intricate gene regulatory networks. In sea urchin embryos,... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Anand S & McClay D. Evi1 is necessary for late activation of delta-notch signaling in sea urchin embryos. bioRxiv [preprint] 2025.04.01.646662; doi: https://doi.org/10.1101/2025.04.01.646662. |
SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish
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Citation:
J Cell Physiol. 2025 Mar;240(3):e70023. doi: 10.1002/jcp.70023. PMID: 40134128; PMCID: PMC11937623 Epub:
Not Epub Abstract:
Hematopoietic stem and progenitor cells (HSPCs) play a pivotal role in blood cell production, maintaining the health and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oh CK, Kim MS, Shin U, Kang JW, Kim YH, Ko HS, Ra JS, Ahn S, Choi EY, Yu S, Nam U, Choi T, Myung K, Lee Y. SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish. J Cell Physiol. 2025 Mar;240(3):e70023. doi: 10.1002/jcp.70023. PMID: 40134128; PMCID: PMC11937623. |