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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Variants of NAV3, a neuronal morphogenesis protein, cause intellectual disability, developmental delay, and microcephaly
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Citation:
Commun Biol. 2024 Jul 8;7(1):831 Epub:
Not Epub Abstract:
Microtubule associated proteins (MAPs) are widely expressed in the central nervous system, and have established roles in cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ghaffar A, Akhter T, Strømme P, Misceo D, Khan A, Frengen E, Umair M, Isidor B, Cogné B, Khan AA, Bruel AL, Sorlin A, Kuentz P, Chiaverini C, Innes AM, Zech M, Baláž M, Havrankova P, Jech R, Ahmed ZM, Riazuddin S, Riazuddin S. Variants of NAV3, a neuronal morphogenesis protein, cause intellectual disability, developmental delay, and microcephaly. Commun Biol. 2024 Jul 8;7(1):831. |
The intracellular domain of Sema6A is essential for development of the zebrafish retina
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Citation:
J Cell Sci jcs.261469 Epub:
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Semaphorin6A (Sema6A) is a repulsive guidance molecule that plays many roles in central nervous system, heart, and bone... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dumas CM, St. Clair RM, Lasseigne AM, Ballif BA, Ebert AM. The intracellular domain of Sema6A is essential for development of the zebrafish retina. J Cell Sci jcs.261469. |
Oxysterol-binding protein like 7 deficiency leads to ER stress mediated apoptosis in podocytes and proteinuria
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Citation:
Am J Physiol Renal Physiol. 2024 Jul 4 Epub:
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Chronic kidney disease (CKD) is associated with renal lipid dysmetabolism among a variety of other pathways. We recently... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Duara J, Torres MF, Gurumani M, Molina David J, Njeim R, Kim JJ, Mitrofanova A, Ge M, Sloan AJ, Müller-Deile J, Schiffer M, Merscher S, Fornoni A. Oxysterol-binding protein like 7 deficiency leads to ER stress mediated apoptosis in podocytes and proteinuria. Am J Physiol Renal Physiol. 2024 Jul 4. |
Reversion induced LIM domain protein (RIL) is a Daam1-interacting protein and regulator of the actin cytoskeleton during non-canonical Wnt signaling
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Citation:
Developmental Biology. 2024 July 03 Epub:
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The Daam1 protein regulates Wnt-induced cytoskeletal changes during vertebrate gastrulation though its full mode of action and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mezzacappa C, Komiya Y, Habas R. Reversion induced LIM domain protein (RIL) is a Daam1-interacting protein and regulator of the actin cytoskeleton during non-canonical Wnt signaling. Developmental Biology. 2024 July 03. |
Fbxo28 is essential for spindle migration and morphology during mouse oocyte meiosis I
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Citation:
International Journal of Biological Macromolecules. 2024 July 01 Epub:
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Spindle migration and assembly regulates asymmetric oocyte division, which is essential for fertility. Fbxo28, as a member of... Delivery Method:
microinjection Organism or Cell Type:
mouse oocytes Citation Extract: Chang H, Huang C, Cheng S, Li J, Wang X. Fbxo28 is essential for spindle migration and morphology during mouse oocyte meiosis I. International Journal of Biological Macromolecules. 2024 July 01. |
Primary cilia formation requires the Leigh syndrome–associated mitochondrial protein NDUFAF2
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Citation:
J Clin Invest. 2024;134(13):e175560 Epub:
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Mitochondria-related neurodegenerative diseases have been implicated in the disruption of primary cilia function. Mutation in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lo CH, Liu Z, Chen S, Lin F, Berneshawi AR, Yu CQ, Koo EB, Kowal TJ, Ning K, Hu Y, Wang WJ, Liao YJ, Sun Y. Primary cilia formation requires the Leigh syndrome–associated mitochondrial protein NDUFAF2. J Clin Invest. 2024;134(13):e175560. |
MDB-06. Alternative Splicing Mediated By Otx2 Drives The Development Of Group 3 Medulloblastoma
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Citation:
Neuro Oncol. 2024 Jun 18;26(Suppl 4):0 Epub:
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OTX2 is a transcription factor and known molecular hallmark of Group 3 medulloblastoma (MB). While previous studies have... Organism or Cell Type:
cell culture; in vivo Citation Extract: Saulnier, O, Zagozewski, J, Liang L, Hendrikse LD, Layug P, Gordon V., Aldinger KA, Haldipur P, Borlase S, Coudière-Morrison L, Cai T, Martell E, Palidwor G, Porter CJ, Richard S, Sharif T, Doble BW, Millen KJ, Taylor MD, Werbowetski-Ogilvie TE. MDB-06. Alternative Splicing Mediated By Otx2 Drives The Development Of Group 3 Medulloblastoma. Neuro Oncol. 2024 Jun 18;26(Suppl 4):0. |
Electroacupuncture facilitates vascular normalization by inhibiting Glyoxalase1 in endothelial cells to attenuate glycolysis and angiogenesis in triple-negative breast cancer
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Citation:
Cancer Lett. 2024 Jun 29;598:217094. doi: 10.1016/j.canlet.2024.217094. Epub ahead of print. PMID: 38945204 Epub:
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Recent therapeutic strategies for the treatment of triple-negative breast cancer (TNBC) have shifted the focus from vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wan YX, Qi XW, Lian YY, Liu ZY, Wang H, Qiu YQ, Zhang CG, Li WN, Jiang HL, Yang DH, Zhao W, Chen ZS, Huang JC. Electroacupuncture facilitates vascular normalization by inhibiting Glyoxalase1 in endothelial cells to attenuate glycolysis and angiogenesis in triple-negative breast cancer. Cancer Lett. 2024 Jun 29;598:217094. doi: 10.1016/j.canlet.2024.217094. Epub ahead of print. PMID: 38945204. |
Beyond ribosomal function: RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing
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Citation:
Acta Pharmaceutica Sinica B. Available online 29 June 2024 Epub:
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Cholangiocarcinoma (CCA) is a bile duct malignancy with a dismal prognosis. This study systematically investigated the role of... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cholangiocarcinoma (CCA) cells; patient-derived organoids Citation Extract: Fu W, Lin Y, Bai M, Yao J, Huang C, Gao L, Mi N, Ma H, Tian L, Yue P, Zhang Y, Zhang J, Ren Y, Ding L, Dai L, Leung JW, Yuan J, Zhang W, Meng W. Beyond ribosomal function: RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing. Acta Pharmaceutica Sinica B. Available online 29 June 2024. |
Differential cellular stiffness across tissues that contribute to Xenopus neural tube closure
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Citation:
Dev Growth Differ. 2024 Jun 26. doi: 10.1111/dgd.12936. Epub ahead of print. PMID: 38925637 Epub:
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During the formation of the neural tube, the primordium of the vertebrate central nervous system, the actomyosin activity of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Suzuki M, Yasue N, Ueno N. Differential cellular stiffness across tissues that contribute to Xenopus neural tube closure. Dev Growth Differ. 2024 Jun 26. doi: 10.1111/dgd.12936. Epub ahead of print. PMID: 38925637. |