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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12237 scientific papers returned from the database with the search filters currently being used below.
There are 12237 scientific papers returned from the database with the search filters currently being used below.
Protocol for manipulating mRNA splicing via vivo-morpholino in early-activating muscle stem cells
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Citation:
STAR Protoc. 2026 Aug 20;7(3):104796 Epub:
Not Epub Abstract:
Muscle stem cells (MuSCs), also called satellite cells (SCs), are essential for skeletal muscle regeneration. SCs undergo rapid... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Tg:Pax7nGFP mice; muscle stem cells (MuSCs) also called satellite cells (SCs) Citation Extract: Lin K, Yin Y, Cheung TH. Protocol for manipulating mRNA splicing via vivo-morpholino in early-activating muscle stem cells. STAR Protoc. 2026 Aug 20;7(3):104796. |
Peptide-phosphorodiamidate morpholino oligomer therapy for dysferlinopathy induces pseudoexon skipping and restoration of functional protein
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Citation:
JCI Insight. 2026 Jul 14;11(16):e204742 Epub:
Not Epub Abstract:
The dysferlinopathies are a spectrum of autosomal recessive muscle diseases caused by mutations in the dysferlin gene (DYSF).... Delivery Method:
Endo-Porter for myotubes, Pip9b2 peptide-linked for mice, DNA-RNA hybrids with cholesterol conjugated to a nucleic acid strand that is complementary to PMO for mice; intravenous (i.v.) for mice Organism or Cell Type:
patient-derived myotubes; PE44.1 mice Citation Extract: Gooding JE, Park G, Wagh A, Watts JK, Dominov JA, Brown RH Jr. Peptide-phosphorodiamidate morpholino oligomer therapy for dysferlinopathy induces pseudoexon skipping and restoration of functional protein. JCI Insight. 2026 Jul 14;11(16):e204742. |
Sunitinib induces macrophage dysfunction and impaired tissue regeneration through suppression of PPARγ
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Citation:
Front. Immunol. (2026) 17:1900449. doi: 10.3389/fimmu.2026.1900449 Epub:
Not Epub Abstract:
Background: Sunitinib is a widely used multi-target tyrosine kinase inhibitor associated with side effects that may impair... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Z, Qiao Q, Li J, Li Q, Yang Y, Zhou Y, Huang H, Chen D, Wang Y and Guo Y. Sunitinib induces macrophage dysfunction and impaired tissue regeneration through suppression of PPARγ. Front. Immunol. (2026) 17:1900449. doi: 10.3389/fimmu.2026.1900449. |
An antisense method for efficient exon skipping and its application to Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2026 Aug 18;123(33):e2606494123 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping has been used to treat Duchenne muscular dystrophy (DMD) by restoring the DMD reading frame to... Delivery Method:
intravenous (i.v.) infusion for monkeys and injection for mice, no transfection for cells Organism or Cell Type:
huΔ52 (exon 52 deleted) mice, cynomolgus monkeys; rhabdomyosarcoma (RD) cells Citation Extract: Feng P, Gao P, Meng S, Yuan Y, Krainer AR, Hua Y. An antisense method for efficient exon skipping and its application to Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2026 Aug 18;123(33):e2606494123. |
Znf131 is required for gastrulation and neurulation in early Xenopus development
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Citation:
Differentiation. 2026 Aug 17:100989 Epub:
Not Epub Abstract:
Early vertebrate development involves several highly orchestrated morphogenic movements. Two key movements are gastrulation,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Knapp J, Cowan RW, Mersereau J, Park JI, Mohammadi D, McCrea PD, Marsden M, Daniel JM. Znf131 is required for gastrulation and neurulation in early Xenopus development. Differentiation. 2026 Aug 17:100989. |
Facile Siderophore Assembly Enables Bacterial Delivery of Nucleic Acid Therapeutics
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Citation:
ACS Chem Biol. 2026 Aug 19 Epub:
Not Epub Abstract:
Antibiotic resistance is an increasing threat to modern medicine that calls for the discovery of new antibiotics. RNA targeting... Delivery Method:
PMO-siderophore conjugate Organism or Cell Type:
E. coli Citation Extract: Ramu H, Kuijken P, Poulladofonou G, Pals MJ, Summerton D, Li YF, Velema WA. Facile Siderophore Assembly Enables Bacterial Delivery of Nucleic Acid Therapeutics. ACS Chem Biol. 2026 Aug 19. |
Spermine oxidase promotes oxidative stress during islet inflammation
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Citation:
J Biol Chem. 2026 Aug 7:113412 Epub:
Not Epub Abstract:
Diabetes is characterized by impaired glucose homeostasis resulting from dysfunction and loss of insulin-producing islet β... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Checkcinco C, Hammoud B, Saavedra XS, Puente AA, Shah H, Tersey SA, Anderson RM, Mirmira RG. Spermine oxidase promotes oxidative stress during islet inflammation. J Biol Chem. 2026 Aug 7:113412. |
Architecture of distal tips of motile cilia is shaped by the pseudoenzyme Jhc1 in non-mammalian vertebrates
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Citation:
Cell Rep. 2026 Jul 31;45(8):117727 Epub:
Not Epub Abstract:
Motile cilia are evolutionarily conserved organelles performing essential roles in development and tissue homeostasis. Unlike... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Hong J, Nair SR, Atayeter E, Jo EL, Gray RS, Young RL, Wallingford JB. Architecture of distal tips of motile cilia is shaped by the pseudoenzyme Jhc1 in non-mammalian vertebrates. Cell Rep. 2026 Jul 31;45(8):117727. |
Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody–Oligonucleotide Conjugates with High Drug-to-Antibody Ratios
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Citation:
J. Med. Chem. 2026; https://doi.org/10.1021/acs.jmedchem.6c00565 Epub:
Not Epub Abstract:
Antibody–oligonucleotide conjugates (AOCs) enable targeted delivery of small interfering RNAs (siRNAs) by coupling them to... Delivery Method:
RNA/PMO heteroduplex; Lipofectamine RNAiMAX for cells, intravenous (i.v) injection for mice Organism or Cell Type:
cell culture: SJCRH30; Hsd:ICR mice Citation Extract: Michael Cochran, Subbarao Nallagatla, Giuseppe Dello Iacono, Sami Abdulkadir, Danny Arias, Maryam Jordan, Hae Won Kwon, Arthur Levin, Michael Hood, Philip Kovach, Aidan Kim, Rob Burke, Barbora Malecova, Venkata Ramana Doppalapudi. Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody–Oligonucleotide Conjugates with High Drug-to-Antibody Ratios. J. Med. Chem. 2026; https://doi.org/10.1021/acs.jmedchem.6c00565. |
Astrocyte activation mediates UV filter PBSA-induced impairment of neurogenesis via the rxrga/tsp-1 axis during a sensitive developmental window in early life stage zebrafish
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Citation:
Chem Biol Interact. 2026 Aug 7:112290 Epub:
Not Epub Abstract:
2-phenylbenzimidazole-5-sulfonic acid (PBSA), a widely used organic UV filter, is frequently detected in aquatic environments,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Q, Tian L, Wang J, Qi C, Qian Z, Liu Y, Zhou Y, Chen X, Tao J. Astrocyte activation mediates UV filter PBSA-induced impairment of neurogenesis via the rxrga/tsp-1 axis during a sensitive developmental window in early life stage zebrafish. Chem Biol Interact. 2026 Aug 7:112290. |