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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking

Authors:
Zheng L, Duan X, Huang W, Luo Y, Wu Y, Lin Q, Wu X, Han L, Shen W
Citation:
Commun Biol. 2026 Jan 9. doi: 10.1038/s42003-025-09507-5. Epub ahead of print. PMID: 41507541
Epub:
Not Epub
Abstract:
Environmental light significantly influences neural development, yet the specific mechanisms underlying the effects of...
Link:
https://www.nature.com/articles/s42003-025-09507-5
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zheng L, Duan X, Huang W, Luo Y, Wu Y, Lin Q, Wu X, Han L, Shen W. Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking. Commun Biol. 2026 Jan 9. doi: 10.1038/s42003-025-09507-5. Epub ahead of print. PMID: 41507541.

Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo

Authors:
Mishra N, Li YI, Hannezo E, Heisenberg CP
Citation:
Nat. Phys. (2026). https://doi.org/10.1038/s41567-025-03122-1
Epub:
Not Epub
Abstract:
Early embryo geometry is one of the most invariant species-specific traits, yet its role in ensuring developmental...
Link:
https://www.nature.com/articles/s41567-025-03122-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mishra N, Li YI, Hannezo E, Heisenberg CP. Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo. Nat. Phys. (2026). https://doi.org/10.1038/s41567-025-03122-1.

Endothelial Cell-Specific Molecule-1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Authors:
Chen C, Ge X, Fu D, Mei H, Lv F, Yang C, Lu J, Shen X, Li B, Wang X, Liu D
Citation:
Adv Sci (Weinh). 2026 Jan 9:e15994. doi: 10.1002/advs.202515994. Epub ahead of print. PMID: 41517829
Epub:
Not Epub
Abstract:
Deficiencies in endogenous anticoagulation pathways can lead to vascular occlusion and thrombosis. Endothelial cell-specific...
Link:
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515994
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen C, Ge X, Fu D, Mei H, Lv F, Yang C, Lu J, Shen X, Li B, Wang X, Liu D. Endothelial Cell-Specific Molecule-1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis. Adv Sci (Weinh). 2026 Jan 9:e15994. doi: 10.1002/advs.202515994. Epub ahead of print. PMID: 41517829.

Cardiac and skeletal muscle delivery of biotherapeutics with a blood vessel epicardial substance-targeting peptide

Authors:
Wang B, Cao J, Wu J, Zhao Y, Zhang Y, Abendroth F, Lin C, Zhong L, Yu H, Seow Y, Ou M, Vázquez O, Mei L, Yin H, Han G
Citation:
Biomaterials. 2026 Jan 4;329:123986. doi: 10.1016/j.biomaterials.2026.123986. Epub ahead of print. PMID: 41506143
Epub:
Not Epub
Abstract:
Although peptide-based delivery strategies show promise for muscle and heart diseases, delivery of biotherapeutics to both...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0142961226000104
Delivery Method:
BV2 peptide-linked, exosome; injection
Organism or Cell Type:
mdx and dystrophin/utrophin double-knockout (DKO) mice
Citation Extract:
Wang B, Cao J, Wu J, Zhao Y, Zhang Y, Abendroth F, Lin C, Zhong L, Yu H, Seow Y, Ou M, Vázquez O, Mei L, Yin H, Han G. Cardiac and skeletal muscle delivery of biotherapeutics with a blood vessel epicardial substance-targeting peptide. Biomaterials. 2026 Jan 4;329:123986. doi: 10.1016/j.biomaterials.2026.123986. Epub ahead of print. PMID: 41506143.

dock11 Knockdown in Zebrafish Disrupts Embryogenesis: Insights Into the Genetic Causes of Early Pregnancy Loss

Authors:
Liu C, Wang M, Chen F, Chen M, Yao Y, Huang W
Citation:
J Cell Mol Med. 2026 Jan;30(1):e71017. doi: 10.1111/jcmm.71017. PMID: 41503681; PMCID: PMC12780853
Epub:
Not Epub
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12780853/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu C, Wang M, Chen F, Chen M, Yao Y, Huang W. dock11 Knockdown in Zebrafish Disrupts Embryogenesis: Insights Into the Genetic Causes of Early Pregnancy Loss. J Cell Mol Med. 2026 Jan;30(1):e71017. doi: 10.1111/jcmm.71017. PMID: 41503681; PMCID: PMC12780853.

Linear ubiquitination triggers Amph-mediated T-tubule biogenesis

Authors:
Kawaguchi K, Hama Y, Yoshikawa H, Nishino K, Morimoto K, Nakamura T, Koizumi M, Sakamaki Y, Abe K, Kakuta S, Ichimura K, Ikeda F, Kosako H, Fujita N
Citation:
Sci Adv. 2026 Jan 9;12(2):eady4934. doi: 10.1126/sciadv.ady4934. Epub 2026 Jan 7. PMID: 41499502; PMCID: PMC12778051
Epub:
Not Epub
Abstract:
Transverse tubules (T-tubules) are invaginations of the muscle plasma membrane that facilitate rapid transmission of action...
Link:
https://www.science.org/doi/10.1126/sciadv.ady4934
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kawaguchi K, Hama Y, Yoshikawa H, Nishino K, Morimoto K, Nakamura T, Koizumi M, Sakamaki Y, Abe K, Kakuta S, Ichimura K, Ikeda F, Kosako H, Fujita N. Linear ubiquitination triggers Amph-mediated T-tubule biogenesis. Sci Adv. 2026 Jan 9;12(2):eady4934. doi: 10.1126/sciadv.ady4934. Epub 2026 Jan 7. PMID: 41499502; PMCID: PMC12778051.

Foxi1 regulates multipotent mucociliary progenitors and ionocyte specification through transcriptional and epigenetic mechanisms

Authors:
Bowden S, Brislinger-Engelhardt MM, Hansen M, Andricek A, Temporal-Plo A, Weber D, Hägele S, Lorenz F, Litwin T, Kreutz C, Walentek P
Citation:
PLoS Biol. 2026 Jan 5;24(1):e3003583. doi: 10.1371/journal.pbio.3003583. PMID: 41490055; PMCID: PMC12768278
Epub:
Not Epub
Abstract:
Foxi1 is a master regulator of ionocytes (ISCs/INCs) across species and organs. Two subtypes of ISCs exist, and both α- and β-...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12768278/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bowden S, Brislinger-Engelhardt MM, Hansen M, Andricek A, Temporal-Plo A, Weber D, Hägele S, Lorenz F, Litwin T, Kreutz C, Walentek P. Foxi1 regulates multipotent mucociliary progenitors and ionocyte specification through transcriptional and epigenetic mechanisms. PLoS Biol. 2026 Jan 5;24(1):e3003583. doi: 10.1371/journal.pbio.3003583. PMID: 41490055; PMCID: PMC12768278.

MMS22L is a novel key actor of normal and pathological erythropoiesis

Authors:
Colin E, Ferrer-Vicens I, Brook D, Salma M, Andrieu-Soler C, Bayard E, Fernandes A, Brouzes C, Lefèvre C, Duval R, Dussiot M, Trovati T, Courtois G, Azouzi S, Zarhrate M, Lambilliotte A, Park S, Carpentier B, Colard M, Manceau S, Moshous D, Mayeux P, Gautier EF, Miccio A, Soulier J, Vainchenker W, Shlush L, Da Costa L, Frayne J, Soler E, Hermine O, Couronné L
Citation:
Hemasphere. 2025 Dec 23;9(12):e70264. doi: 10.1002/hem3.70264. PMID: 41446536; PMCID: PMC12723439
Epub:
Not Epub
Abstract:
The emergence of next-generation sequencing techniques has led to the genetic characterization of numerous congenital erythroid...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12723439/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Colin E, Ferrer-Vicens I, Brook D, Salma M, Andrieu-Soler C, Bayard E, Fernandes A, Brouzes C, Lefèvre C, Duval R, Dussiot M, Trovati T, Courtois G, Azouzi S, Zarhrate M, Lambilliotte A, Park S, Carpentier B, Colard M, Manceau S, Moshous D, Mayeux P, Gautier EF, Miccio A, Soulier J, Vainchenker W, Shlush L, Da Costa L, Frayne J, Soler E, Hermine O, Couronné L. MMS22L is a novel key actor of normal and pathological erythropoiesis. Hemasphere. 2025 Dec 23;9(12):e70264. doi: 10.1002/hem3.70264. PMID: 41446536; PMCID: PMC12723439.

Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development

Authors:
Oak MS, Stock M, Janeva A, Mezes M, Hynes-Allen AM, Straub T, Forné I, Ettinger A, Hamperl S, Imhof A, van den Ameele J, Scialdone A, Hörmanseder E
Citation:
Nat Commun. 2025 Dec 19;16(1):11334. doi: 10.1038/s41467-025-67692-7. PMID: 41419741; PMCID: PMC12722762
Epub:
Not Epub
Abstract:
In vertebrate embryos, gene expression is first initiated at zygotic genome activation (ZGA). Maternally expressed...
Link:
https://www.nature.com/articles/s41467-025-67692-7
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Oak MS, Stock M, Janeva A, Mezes M, Hynes-Allen AM, Straub T, Forné I, Ettinger A, Hamperl S, Imhof A, van den Ameele J, Scialdone A, Hörmanseder E. Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development. Nat Commun. 2025 Dec 19;16(1):11334. doi: 10.1038/s41467-025-67692-7. PMID: 41419741; PMCID: PMC12722762.

Glis3 as a critical regulator of Pit1-lineages and renal functions

Authors:
Rurale G, Gentile I, Persani L, Marelli F
Citation:
J Mol Med (Berl). 2025 Dec 29;104(1):19. doi: 10.1007/s00109-025-02611-3. PMID: 41457180; PMCID: PMC12745328
Epub:
Not Epub
Abstract:
The Krüppel-like GLIS3 transcription factor acts as an effector on the sonic hedgehog (Shh) pathway, regulating several...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12745328/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rurale G, Gentile I, Persani L, Marelli F. Glis3 as a critical regulator of Pit1-lineages and renal functions. J Mol Med (Berl). 2025 Dec 29;104(1):19. doi: 10.1007/s00109-025-02611-3. PMID: 41457180; PMCID: PMC12745328.

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