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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12263 scientific papers returned from the database with the search filters currently being used below.

Redirecting full-length FLT1 expression towards its soluble isoform by targeting alternative polyadenylation promotes postischaemic angiogenesis

Authors:
Bundalo M, Vorlova S, Ulrich J, Rizzo G, Butt E, Bartolomaeus H, Ali H, Barbieri R, Richter L, Höna L, Egg M, Bock J, Schäfer S, Amézaga Solé N, Rosa A, Cochain C, Beilhack A, Kastenmüller W, Henke E, Skryabin BV, Rozhdestvensky TS, Wildgruber M, Alitalo K, Lorenz K, Kuhn M, Zernecke A
Citation:
Cardiovasc Res. 2026 Oct 5:cvag198. doi: 10.1093/cvr/cvag198
Epub:
Not Epub
Abstract:
Aims: Vascular endothelial growth factors (VEGFs) and their endothelial tyrosine kinase receptors are crucial mediators of...
Delivery Method:
Endo-Porter
Organism or Cell Type:
mouse lung endothelial cells
Citation Extract:
Bundalo M, Vorlova S, Ulrich J, Rizzo G, Butt E, Bartolomaeus H, Ali H, Barbieri R, Richter L, Höna L, Egg M, Bock J, Schäfer S, Amézaga Solé N, Rosa A, Cochain C, Beilhack A, Kastenmüller W, Henke E, Skryabin BV, Rozhdestvensky TS, Wildgruber M, Alitalo K, Lorenz K, Kuhn M, Zernecke A. Redirecting full-length FLT1 expression towards its soluble isoform by targeting alternative polyadenylation promotes postischaemic angiogenesis. Cardiovasc Res. 2026 Oct 5:cvag198. doi: 10.1093/cvr/cvag198.

SMCHD1 is a target for gene activation therapy to treat Prader-Willi syndrome

Authors:
Iminitoff M, Le Fevre A, Cameron T, Vanyai HK, Chew C, Kinkel SA, Breslin K, Theiß S, Gouil Q, Thomas M, Murphy JM, Schaaf CP, Keniry A, Blewitt ME
Citation:
Sci Adv. 2026 Oct 9;12(41):eaej5702
Epub:
Not Epub
Abstract:
Prader-Willi syndrome (PWS) is a neurodevelopmental disorder caused by loss of expression from the active paternal allele at an...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
patient-derived iPSCs differentiated into neural progenitor cells
Citation Extract:
Iminitoff M, Le Fevre A, Cameron T, Vanyai HK, Chew C, Kinkel SA, Breslin K, Theiß S, Gouil Q, Thomas M, Murphy JM, Schaaf CP, Keniry A, Blewitt ME. SMCHD1 is a target for gene activation therapy to treat Prader-Willi syndrome. Sci Adv. 2026 Oct 9;12(41):eaej5702.

TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasis

Authors:
Sharma N, Tanwar A, Zheng C, Ambudkar I, Motiani RK
Citation:
J Biol Chem. 2026 Oct 8:113624
Epub:
Not Epub
Abstract:
Transient Receptor Potential Melastatin 2 (TRPM2), a Ca2+-permeable cation channel, regulates innate and adaptive immunity and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma N, Tanwar A, Zheng C, Ambudkar I, Motiani RK. TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasis. J Biol Chem. 2026 Oct 8:113624.

Loss of nono impairs cardiac morphogenesis and excitation–contraction coupling via the PI3K/Akt pathway in zebrafish

Authors:
Zhang Q, Yan C, Liu H, Zhao H, Sun K, Peng X, Lin Y, Wang X, Lei Y, Cao H
Citation:
Sci Rep (2026)
Epub:
Not Epub
Abstract:
Pathogenic variants in NONO are clinically linked to congenital heart disease (CHD), but in vivo mechanisms and gene-targeted...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Q, Yan C, Liu H, Zhao H, Sun K, Peng X, Lin Y, Wang X, Lei Y, Cao H. Loss of nono impairs cardiac morphogenesis and excitation–contraction coupling via the PI3K/Akt pathway in zebrafish. Sci Rep (2026).

MicroRNA miR-219 is required for neural border and neural crest development in Xenopus neurulas

Authors:
Godden AM, Ward N, Sittewelle M, Mir R, Kotov A, Antonaci M, Monsoro-Burq AH, Wheeler GN
Citation:
Dev Biol. 2026 Oct 9:S0012-1606(26)00208-3
Epub:
Not Epub
Abstract:
At head levels, neural crest (NC) multipotent stem cells are specified in the ectoderm territory located between the anterior...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Godden AM, Ward N, Sittewelle M, Mir R, Kotov A, Antonaci M, Monsoro-Burq AH, Wheeler GN. MicroRNA miR-219 is required for neural border and neural crest development in Xenopus neurulas. Dev Biol. 2026 Oct 9:S0012-1606(26)00208-3.

LncRNA TAAL Regulates TIE1-Mediated Vascular Remodeling and Is Associated With Diabetic Retinopathy

Authors:
Ranjan G, Arora S, Sharma S, Bhoyar RC, Senthivel V, Narula R, Scaria V, Chakrabarti S, Kaur I, Sivasubbu S, Motiani RK
Citation:
Arterioscler Thromb Vasc Biol. 2026 Oct 8
Epub:
Not Epub
Abstract:
Background: TIE1 is an endothelial receptor tyrosine kinase, which plays a crucial role in vascular development and remodeling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ranjan G, Arora S, Sharma S, Bhoyar RC, Senthivel V, Narula R, Scaria V, Chakrabarti S, Kaur I, Sivasubbu S, Motiani RK. LncRNA TAAL Regulates TIE1-Mediated Vascular Remodeling and Is Associated With Diabetic Retinopathy. Arterioscler Thromb Vasc Biol. 2026 Oct 8.

Identification of Sodium/Myo-Inositol Transporter 1 as a Major Determinant of Arterial Contractility

Authors:
Forrester EA, Lau S, Benitez-Angeles M, Garland CJ, Barrese V, Albert AP, Greenwood IA
Citation:
FASEB J. 2026 Sep 30;40(18):e72268
Epub:
Not Epub
Abstract:
As the sodium/myo-inositol transporter (SMIT1) is a positive regulator of Kv7.4/7.5 channels in arterial smooth muscle, we...
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
WistarHan rat mesenteric arteries
Citation Extract:
Forrester EA, Lau S, Benitez-Angeles M, Garland CJ, Barrese V, Albert AP, Greenwood IA. Identification of Sodium/Myo-Inositol Transporter 1 as a Major Determinant of Arterial Contractility. FASEB J. 2026 Sep 30;40(18):e72268.

Plag1 Regulates Sensorimotor Modulation in Zebrafish

Authors:
Gasperoni JG, Fuller JN, Lewis AL, Johnson TK, De Groef B, Dworkin S
Citation:
Int J Dev Neurosci. 2026 Oct;86(6):e70185. doi: 10.1002/jdn.70185
Epub:
Not Epub
Abstract:
The zinc finger transcription factor PLAG1 has been implicated in multiple diverse cellular processes, yet its role in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gasperoni JG, Fuller JN, Lewis AL, Johnson TK, De Groef B, Dworkin S . Plag1 Regulates Sensorimotor Modulation in Zebrafish. Int J Dev Neurosci. 2026 Oct;86(6):e70185. doi: 10.1002/jdn.70185.

Downstream of β-catenin: A positive feedback loop between Goosecoid and Nodals in Spemann's organizer

Authors:
Azbazdar Y, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2026 Sep 29;123(39):e2610127123
Epub:
Not Epub
Abstract:
We report on the role of the homeobox gene goosecoid (gsc) within an epistatic pathway that mediates body axis formation in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Azbazdar Y, De Robertis EM. Downstream of β-catenin: A positive feedback loop between Goosecoid and Nodals in Spemann's organizer. Proc Natl Acad Sci U S A. 2026 Sep 29;123(39):e2610127123.

Improving the beneficial effects of HDAC8 inhibition by simultaneously activation of SIRT1 in a zebrafish model of Duchenne muscular dystrophy

Authors:
Carbone S, Brix A, Lociuro L, Belleri L, Gjana O, Cannone E, Bonusi S, Schiavone M, Marozzi A, Del Bene F, Braccia C, Andolfo A, De Palma C, Pezzotta A, Pistocchi A
Citation:
Pharmacol Res. 2026 Sep 20:108477
Epub:
Not Epub
Abstract:
Duchenne Muscular Dystrophy (DMD) is a severe genetic disorder characterized by progressive skeletal muscle degeneration,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carbone S, Brix A, Lociuro L, Belleri L, Gjana O, Cannone E, Bonusi S, Schiavone M, Marozzi A, Del Bene F, Braccia C, Andolfo A, De Palma C, Pezzotta A, Pistocchi A. Improving the beneficial effects of HDAC8 inhibition by simultaneously activation of SIRT1 in a zebrafish model of Duchenne muscular dystrophy. Pharmacol Res. 2026 Sep 20:108477.

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