You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
In a zebrafish biomedical model of human Allan-Herndon-Dudley syndrome impaired MTH signaling leads to decreased neural cell diversity
|
Citation:
Front Endocrinol. 2023;14:1157685. doi:10.3389/fendo.2023.1157685 Epub:
Not Epub Abstract:
Background: Maternally derived thyroid hormone (T3) is a fundamental factor for vertebrate neurodevelopment. In humans,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Silva N, Campinho MA. In a zebrafish biomedical model of human Allan-Herndon-Dudley syndrome impaired MTH signaling leads to decreased neural cell diversity. Front Endocrinol. 2023;14:1157685. doi:10.3389/fendo.2023.1157685. |
Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
|
Citation:
Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2220911120. doi: 10.1073/pnas.2220911120. Epub 2023 May 1 Epub:
Not Epub Abstract:
Narcolepsy with cataplexy is a sleep disorder caused by deficiency in the hypothalamic neuropeptide hypocretin/orexin (HCRT),... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Seifinejad A, Ramosaj M, Shan L, Li S, Possovre ML, Pfister C, Fronczek R, Garrett-Sinha LA, Frieser D, Honda M, Arribat Y, Grepper D, Amati F, Picot M, Agnoletto A, Iseli C, Chartrel N, Liblau R, Lammers GJ, Vassalli A, Tafti M. Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2220911120. doi: 10.1073/pnas.2220911120. Epub 2023 May 1. |
Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells
|
Citation:
Stem Cell Res Ther. 2023 Apr 30;14(1):117. doi: 10.1186/s13287-023-03328-1 Epub:
Not Epub Abstract:
Background: In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li H, Luo Q, Cai S, Tie R, Meng Y, Shan W, Xu Y, Zeng X, Qian P, Huang H. Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells. Stem Cell Res Ther. 2023 Apr 30;14(1):117. doi: 10.1186/s13287-023-03328-1. |
mRNA Location and Translation Rate Determine Protein Targeting to Dual Destinations
|
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.04.24.538105 Epub:
Not Epub Abstract:
Numerous proteins are targeted to two or multiple subcellular destinations where they exert distinct functional consequences.... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: MDA-MB-231 Citation Extract: Gasparski AN, Moissoglu K, Pallikkuth S, Meydan S, Guydosh NR, Mili S. mRNA Location and Translation Rate Determine Protein Targeting to Dual Destinations. bioRxiv. 2023;[preprint] doi:10.1101/2023.04.24.538105. |
Epigenetic landscape reveals MECOM as an endothelial lineage regulator
|
Citation:
Nat Commun. 2023;14:2390. doi:/10.1038/s41467-023-38002-w Epub:
Not Epub Abstract:
A comprehensive understanding of endothelial cell lineage specification will advance cardiovascular regenerative medicine.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lv J, Meng S, Gu Q, Zheng R, Gao X, Kim J-d, Chen M, Xia B, Zuo Y, Zhu S, Zhao D, Li Y, Wang G, Wang X, Meng Q, Cao Q, Cooke JP, Fang L, Chen K, Zhang L. Epigenetic landscape reveals MECOM as an endothelial lineage regulator. Nat Commun. 2023;14:2390. doi:/10.1038/s41467-023-38002-w. |
PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma
|
Citation:
Blood. 2022;139(15):2316-37. doi:10.1182/blood.2021014011 Epub:
Not Epub Abstract:
The differentiation of B cells into plasmablasts (PBs) and then plasma cells (PCs) is associated with extensive cell... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Plasmoblasts (PBs) and CD23+ post-activated B cells Citation Extract: Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas-Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T. PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma. Blood. 2022;139(15):2316-37. doi:10.1182/blood.2021014011. |
Deciphering the pathogenesis of retinopathy associated with carnitine palmitoyltransferase I deficiency in zebrafish model
|
Citation:
Biochem Biophys Res Commun. 2023;664:100-7. doi:10.1016/j.bbrc.2023.04.096 Epub:
Not Epub Abstract:
Abstract: Fatty acid oxidation disorders (FAODs) are a group of rare genetic metabolic disorders caused by mutations in genes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ulhaq ZS, Ogino Y, Tse WKF. Deciphering the pathogenesis of retinopathy associated with carnitine palmitoyltransferase I deficiency in zebrafish model. Biochem Biophys Res Commun. 2023;664:100-7. doi:10.1016/j.bbrc.2023.04.096. |
Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish
|
Citation:
Sci Adv. 2023 Apr 28;9(17):eade0631. doi: 10.1126/sciadv.ade0631. Epub 2023 Apr 26 Epub:
Not Epub Abstract:
We report 21 families displaying neurodevelopmental differences and multiple congenital anomalies while bearing a series of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Patterson V, Ullah F, Bryant L, Griffin JN, Sidhu A, Saliganan S, Blaile M, Saenz MS, Smith R, Ellingwood S, Grange DK, Hu X, Mireguli M, Luo Y, Shen Y, Mulhern M, Zackai E, Ritter A, Izumi K, Hoefele J, Wagner M, Riedhammer KM, Seitz B, Robin NH, Goodloe D, Mignot C, Keren B, Cox H, Jarvis J, Hempel M, Gibson CF, Tran Mau-Them F, Vitobello A, Bruel AL, Sorlin A, Mehta S, Raymond FL, Gilmore K, Powell BC, Weck K, Li C, Vulto-van Silfhout AT, Giacomini T, Mancardi MM, Accogli A, Salpietro V, Zara F, Vora NL, Davis EE, Burdine R, Bhoj E. Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish. Sci Adv. 2023 Apr 28;9(17):eade0631. doi: 10.1126/sciadv.ade0631. Epub 2023 Apr 26. |
Voltage-gated sodium channel activity mediates sea urchin larval skeletal patterning through spatial regulation of Wnt5 expression
|
Citation:
Development. 2023 May 4:dev.201460. doi: 10.1242/dev.201460. Online ahead of print Epub:
Not Epub Abstract:
Defining pattern formation mechanisms during embryonic development is important for understanding the etiology of birth defects... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Thomas CF, Hawkins DY, Skidanova V, Marrujo SR, Gibson J, Ye Z, Bradham CA. Voltage-gated sodium channel activity mediates sea urchin larval skeletal patterning through spatial regulation of Wnt5 expression. Development. 2023 May 4:dev.201460. doi: 10.1242/dev.201460. Online ahead of print. |
BMP signaling is required to form the anterior neural plate border in ascidian embryos
|
Citation:
Dev Genes Evol. 2023;[Epub] doi:10.1007/s00427-023-00702-0 Epub:
Not Epub Abstract:
Cranial neurogenic placodes have been considered vertebrate innovations. However, anterior neural plate border (ANB) cells of... Organism or Cell Type:
ascidian Citation Extract: Liu B, Ren X, Satou Y. BMP signaling is required to form the anterior neural plate border in ascidian embryos. Dev Genes Evol. 2023;[Epub] doi:10.1007/s00427-023-00702-0. |