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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11971 scientific papers returned from the database with the search filters currently being used below.

Characterization of Na+ currents regulating intrinsic excitability of optic tectal neurons

Authors:
Thompson AC, Aizenman CD
Citation:
Life Sci Alliance. 2023 Nov 2;7(1):e202302232. doi: 10.26508/lsa.202302232. Print 2024 Jan
Epub:
Not Epub
Abstract:
Developing neurons adapt their intrinsic excitability to maintain stable output despite changing synaptic input. The mechanisms...
Link:
https://www.life-science-alliance.org/content/7/1/e202302232
Delivery Method:
injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Thompson AC, Aizenman CD. Characterization of Na+ currents regulating intrinsic excitability of optic tectal neurons. Life Sci Alliance. 2023 Nov 2;7(1):e202302232. doi: 10.26508/lsa.202302232. Print 2024 Jan.

Interaction of Integrin αvβ8 With Type I Collagen Promotes Squamous Cell Carcinoma Cell Motility via RAC1 Activation

Authors:
Ishida Y, Shintani T, Nobumoto T, Sakurai S, Hamana T, Yanamoto S, Hayashido Y
Citation:
Anticancer Res. 2023 Nov;43(11):4833-4841. doi: 10.21873/anticanres.16680
Epub:
Not Epub
Abstract:
Background/aim: The interaction of integrin αvβ8 with type I collagen was shown to promote oral squamous cell carcinoma (SCC)...
Link:
https://ar.iiarjournals.org/content/43/11/4833.long
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Ca9-22
Citation Extract:
Ishida Y, Shintani T, Nobumoto T, Sakurai S, Hamana T, Yanamoto S, Hayashido Y. Interaction of Integrin αvβ8 With Type I Collagen Promotes Squamous Cell Carcinoma Cell Motility via RAC1 Activation. Anticancer Res. 2023 Nov;43(11):4833-4841. doi: 10.21873/anticanres.16680.

SorCS2 binds progranulin to regulate motor neuron development

Authors:
Thomasen PB, Salasova A, Kjaer-Sorensen K, Woloszczuková L, Lavický J, Login H, Tranberg-Jensen J, Almeida S, Beel S, Kavková M, Qvist P, Kjolby M, Ovesen PL, Nolte S, Vestergaard B, Udrea AC, Nejsum LN, Chao MV, Van Damme P, Krivanek J, Dasen J, Oxvig C, Nykjaer A
Citation:
Cell Rep. 2023 Oct 26;42(11):113333. doi: 10.1016/j.celrep.2023.113333. Online ahead of print
Epub:
Not Epub
Abstract:
Motor neuron (MN) development and nerve regeneration requires orchestrated action of a vast number of molecules. Here, we...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01345-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thomasen PB, Salasova A, Kjaer-Sorensen K, Woloszczuková L, Lavický J, Login H, Tranberg-Jensen J, Almeida S, Beel S, Kavková M, Qvist P, Kjolby M, Ovesen PL, Nolte S, Vestergaard B, Udrea AC, Nejsum LN, Chao MV, Van Damme P, Krivanek J, Dasen J, Oxvig C, Nykjaer A. SorCS2 binds progranulin to regulate motor neuron development. Cell Rep. 2023 Oct 26;42(11):113333. doi: 10.1016/j.celrep.2023.113333. Online ahead of print.

Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration

Authors:
Qin MC, Li JJ, Zheng YT, Li YJ, Zhang YX, Ou RX, He WY, Zhao JM, Liu ST, Liu MH, Lin HY, Gao L
Citation:
Food Funct. 2023 Nov 6. doi: 10.1039/d3fo03858k. Online ahead of print
Epub:
Not Epub
Abstract:
Liver fibrosis (LF) is an important reparative process in response to acute or chronic hepatic injury, which has the potential...
Link:
https://pubs.rsc.org/en/content/articlelanding/2023/FO/D3FO03858K
Organism or Cell Type:
zebrafish
Citation Extract:
Qin MC, Li JJ, Zheng YT, Li YJ, Zhang YX, Ou RX, He WY, Zhao JM, Liu ST, Liu MH, Lin HY, Gao L. Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration. Food Funct. 2023 Nov 6. doi: 10.1039/d3fo03858k. Online ahead of print.

Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis

Authors:
Chen XK, Yi ZN, Lau JJ, Ma AC
Citation:
Autophagy. 2023 Nov 3:1-17. doi: 10.1080/15548627.2023.2274251. Online ahead of print
Epub:
Not Epub
Abstract:
Despite the well-described discrepancy between ATG (macroautophagy/autophagy-related) genes in the regulation of hematopoiesis...
Link:
https://www.tandfonline.com/doi/abs/10.1080/15548627.2023.2274251
Organism or Cell Type:
zebrafish
Citation Extract:
Chen XK, Yi ZN, Lau JJ, Ma AC. Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis. Autophagy. 2023 Nov 3:1-17. doi: 10.1080/15548627.2023.2274251. Online ahead of print.

An Induced Pluripotent Stem Cell-Derived Human Blood-Brain Barrier (BBB) Model to Test the Crossing by Adeno-Associated Virus (AAV) Vectors and Antisense Oligonucleotides

Authors:
Selvakumaran J, Ursu S, Bowerman M, Lu-Nguyen N, Wood MJ, Malerba A, Yáñez-Muñoz RJ
Citation:
Biomedicines. 2023 Oct 4;11(10):2700. doi: 10.3390/biomedicines11102700
Epub:
Not Epub
Abstract:
The blood-brain barrier (BBB) is the specialised microvasculature system that shields the central nervous system (CNS) from...
Link:
https://www.mdpi.com/2227-9059/11/10/2700
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: induced brain microvascular endothelial cells (BMECs)
Citation Extract:
Selvakumaran J, Ursu S, Bowerman M, Lu-Nguyen N, Wood MJ, Malerba A, Yáñez-Muñoz RJ. An Induced Pluripotent Stem Cell-Derived Human Blood-Brain Barrier (BBB) Model to Test the Crossing by Adeno-Associated Virus (AAV) Vectors and Antisense Oligonucleotides. Biomedicines. 2023 Oct 4;11(10):2700. doi: 10.3390/biomedicines11102700.

MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.

Authors:
Serres MP, Shaughnessy R, Escot S, Hammich H, Cuvelier F, Salles A, Rocancourt M, Verdon Q, Gaffuri A-L, Sourigues Y, Malherbe G, Velikovsky L, Chardon F, Sassoon N, Tinevez J-Y, Callebaut I, Formstecher E, Houdusse A, David NB, Pylypenko O, Echard A
Citation:
Dev Cell. 2023;[Epub ahead of print] doi:10.1016/j.devcel.2023.09.010
Epub:
Not Epub
Abstract:
Cilia protrude from the cell surface and play critical roles in intracellular signaling, environmental sensing, and development...
Link:
https://www.cell.com/developmental-cell/pdf/S1534-5807(23)00512-9.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serres MP, Shaughnessy R, Escot S, Hammich H, Cuvelier F, Salles A, Rocancourt M, Verdon Q, Gaffuri A-L, Sourigues Y, Malherbe G, Velikovsky L, Chardon F, Sassoon N, Tinevez J-Y, Callebaut I, Formstecher E, Houdusse A, David NB, Pylypenko O, Echard A. MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.. Dev Cell. 2023;[Epub ahead of print] doi:10.1016/j.devcel.2023.09.010.

Direct TGF-ß signaling via alk4/5/7 pathway is involved in gut bending in sea urchin embryos

Authors:
Suzuki H, Yaguchi S
Citation:
Dev Dyn. 2022 Jan;251(1):226-234. doi: 10.1002/dvdy.442. Epub 2021 Nov 27
Epub:
Not Epub
Abstract:
Background: Precise gastrulation is essential for formation of functional bodies in cnidarians and bilaterians. Previously, by...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.442
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Suzuki H, Yaguchi S. Direct TGF-ß signaling via alk4/5/7 pathway is involved in gut bending in sea urchin embryos. Dev Dyn. 2022 Jan;251(1):226-234. doi: 10.1002/dvdy.442. Epub 2021 Nov 27.

The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling

Authors:
Li Y, Li C, Liu M, Liu S, Liu F, Wang L
Citation:
Development. 2023 Nov 1;150(21):dev201890. doi: 10.1242/dev.201890. Epub 2023 Oct 24
Epub:
Not Epub
Abstract:
In vertebrates, the earliest hematopoietic stem and progenitor cells (HSPCs) are derived from a subset of specialized...
Link:
https://journals.biologists.com/dev/article/150/21/dev201890/334149/The-RNA-binding-protein-CSDE1-promotes
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Li C, Liu M, Liu S, Liu F, Wang L. The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling. Development. 2023 Nov 1;150(21):dev201890. doi: 10.1242/dev.201890. Epub 2023 Oct 24.

Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry

Authors:
Karasawa K, Duchoslav E, Burton L, Kawakami J, Baba T
Citation:
Anal Chem. 2023 Oct 23. doi: 10.1021/acs.analchem.3c03621. Online ahead of print
Epub:
Yes
Abstract:
We report the first sequencing of morpholino antisense oligonucleotides (phosphorodiamidate morpholino oligomers, PMOs) using...
Link:
https://pubs.acs.org/doi/10.1021/acs.analchem.3c03621
Citation Extract:
Karasawa K, Duchoslav E, Burton L, Kawakami J, Baba T. Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry. Anal Chem. 2023 Oct 23. doi: 10.1021/acs.analchem.3c03621. Online ahead of print.

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