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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123 Epub:
Not Epub Abstract:
CD20-directed immunotherapies, such as rituximab, are mainstays of clinical management of mature B-cell neoplasms, previously... Delivery Method:
electroporation of standard Morpholino; Vivo-Morpholino Organism or Cell Type:
cell culture: OCI-Ly8, Raji and MEC-1 Citation Extract: Ang Z, Hayer KE, Diz MT, Schmidt C, Zheng S, Xu F, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Schuster SJ, Thomas-Tikhonenko A. Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123. |
Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney
Citation:
Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666 Epub:
Not Epub Abstract:
Despite significant advances in understanding nephron segment patterning, many questions remain about the underlying genes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wesselman HM, Gatz AE, Pfaff MR, Arceri L, Wingert RA. Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666. |
USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling
Citation:
Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7 Epub:
Not Epub Abstract:
The Wnt-β-catenin signal transduction pathway is essential for embryonic development and adult tissue homeostasis. Wnt... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. |
FGF8 rescues motor deficits in zebrafish model of limb-girdle muscular dystrophy R18
Citation:
Biochem Biophys Res Commun. 2023 Feb 19;652:76-83. doi: 10.1016/j.bbrc.2023.02.046. Online ahead of print Epub:
Not Epub Abstract:
Variants in the gene encoding trafficking protein particle complex 11 (TRAPPC11) cause limb-girdle muscular dystrophy R18 (LGMD... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ulhaq ZS, Ogino Y, Tse WKF. FGF8 rescues motor deficits in zebrafish model of limb-girdle muscular dystrophy R18. Biochem Biophys Res Commun. 2023 Feb 19;652:76-83. doi: 10.1016/j.bbrc.2023.02.046. Online ahead of print. |
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease
Citation:
Nat Commun. 2023 Feb 23;14(1):1009. doi: 10.1038/s41467-023-36277-7 Epub:
Not Epub Abstract:
Mutations in the mitochondrial or nuclear genomes are associated with a diverse group of human disorders characterized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Van Haute L, O'Connor E, Díaz-Maldonado H, Munro B, Polavarapu K, Hock DH, Arunachal G, Athanasiou-Fragkouli A, Bardhan M, Barth M, Bonneau D, Brunetti-Pierri N, Cappuccio G, Caruana NJ, Dominik N, Goel H, Helman G, Houlden H, Lenaers G, Mention K, Murphy D, Nandeesh B, Olimpio C, Powell CA, Preethish-Kumar V, Procaccio V, Rius R, Rebelo-Guiomar P, Simons C, Vengalil S, Zaki MS, Ziegler A, Thorburn DR, Stroud DA, Maroofian R, Christodoulou J, Gustafsson C, Nalini A, Lochmüller H, Minczuk M, Horvath R. TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nat Commun. 2023 Feb 23;14(1):1009. doi: 10.1038/s41467-023-36277-7. |
Neurogenin 2 and Neuronal Differentiation 1 Control Proper Development of the Chick Trigeminal Ganglion and Its Nerve Branches
Citation:
J Dev Biol. 2023 Feb 19;11(1):8. doi: 10.3390/jdb11010008 Epub:
Not Epub Abstract:
The trigeminal ganglion contains the cell bodies of sensory neurons comprising cranial nerve V, which relays information... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Bina P, Hines MA, Sanyal J, Taneyhill LA. Neurogenin 2 and Neuronal Differentiation 1 Control Proper Development of the Chick Trigeminal Ganglion and Its Nerve Branches. J Dev Biol. 2023 Feb 19;11(1):8. doi: 10.3390/jdb11010008. |
Synthesis of Chlorophosphoramidate Monomer Morpholinos and PMOs
Citation:
Curr Protoc. 2023 Feb;3(2):e686. doi: 10.1002/cpz1.686 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMOs) are a successful class of antisense reagents that efficiently modulate... Citation Extract: Kundu J, Ghosh U, Ghosh A, Pattanayak S, Das A, Sinha S. Synthesis of Chlorophosphoramidate Monomer Morpholinos and PMOs. Curr Protoc. 2023 Feb;3(2):e686. doi: 10.1002/cpz1.686. |
p16 INK4A drives non-alcoholic fatty liver disease phenotypes in high fat diet fed mice via biliary e2f1/foxo1/igf-1 signaling
Citation:
Hepatology. 2023 Feb 20. doi: 10.1097/HEP.0000000000000307. Online ahead of print Epub:
Yes Abstract:
Backgroundand aim: Non-alcoholic fatty liver disease (NAFLD) is characterized by steatosis, hepatic inflammation, and fibrosis... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Kundu D, Kennedy L, Zhou T, Ekser B, Meadows V, Sybenga A, Kyritsi K, Chen L, Ceci L, Wu N, Wu C, Glaser S, Carpino G, Onori P, Gaudio E, Alpini G, Francis H. p16 INK4A drives non-alcoholic fatty liver disease phenotypes in high fat diet fed mice via biliary e2f1/foxo1/igf-1 signaling. Hepatology. 2023 Feb 20. doi: 10.1097/HEP.0000000000000307. Online ahead of print. |
Genetic analysis identifies the SLC4A3 anion exchanger as a major gene for short QT syndrome
Citation:
Heart Rhythm. 2023;[Epub] doi:10.1016/j.hrthm.2023.02.010 Epub:
Yes Abstract:
Background: A variant in the SLC4A3 anion exchanger has been identified as a novel cause of short QT syndrome (SQTS), but the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Christiansen MK, Kjær-Sørensen K, Clavsen NC, Dittmann S, Jensen MF, Guldbrandsen HØ, Pedersen LN, Sørensen RH, Lildballe DL, Müller K, Müller P, Vogel K, Rudic B, Borggrefe M, Oxvig C, Aalkjær C, Schulze-Bahr E, Matchkov V, Bundgaard H, Jensen Henrik K. Genetic analysis identifies the SLC4A3 anion exchanger as a major gene for short QT syndrome. Heart Rhythm. 2023;[Epub] doi:10.1016/j.hrthm.2023.02.010. |
Single-cell atavism reveals an ancient mechanism of cell type diversification in a sea anemone
Citation:
Nat Commun. 2023;14:885. doi:10.1038/s41467-023-36615-9 Epub:
Not Epub Abstract:
Cnidocytes are the explosive stinging cells unique to cnidarians (corals, jellyfish, etc). Specialized for prey capture and... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Babonis LS, Enjolras C, Reft AJ, Foster BM, Hugosson F, Ryan JF, Daly M, Martindale MQ. Single-cell atavism reveals an ancient mechanism of cell type diversification in a sea anemone. Nat Commun. 2023;14:885. doi:10.1038/s41467-023-36615-9. |