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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis

Authors:
Li S, Li H, Bennewitz K, Poschet G, Buettner M, Hausser I, Szendroedi J, Nawroth PP, Kroll J
Citation:
Metabolism. 2025 Jan 30:156149. doi: 10.1016/j.metabol.2025.156149. Epub ahead of print. PMID: 39892865
Epub:
Not Epub
Abstract:
Background & aims: Any energy consumption results in the generation of highly reactive dicarbonyls and the need to prevent...
Link:
https://www.metabolismjournal.com/article/S0026-0495(25)00018-6/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li S, Li H, Bennewitz K, Poschet G, Buettner M, Hausser I, Szendroedi J, Nawroth PP, Kroll J. Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis. Metabolism. 2025 Jan 30:156149. doi: 10.1016/j.metabol.2025.156149. Epub ahead of print. PMID: 39892865.

Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos

Authors:
Li X, Xiong G, Luo M, Mao S, Zhang R, Meng Z, Li J, Liao X
Citation:
PLoS One. 2025 Jan 31;20(1):e0315714. doi: 10.1371/journal.pone.0315714. PMID: 39888929; PMCID: PMC11785313
Epub:
Not Epub
Abstract:
Peptidoglycan recognition proteins (PGRPs) are the evolutionarily highly conserved class of pattern recognition receptors,...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11785313/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Xiong G, Luo M, Mao S, Zhang R, Meng Z, Li J, Liao X. Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. PLoS One. 2025 Jan 31;20(1):e0315714. doi: 10.1371/journal.pone.0315714. PMID: 39888929; PMCID: PMC11785313.

Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebra Fish

Authors:
Lu X, Wang X, Li B, Wang X, Duan X, Liu D
Citation:
Arterioscler Thromb Vasc Biol. 2025 Jan 23. doi: 10.1161/ATVBAHA.124.321588. Epub ahead of print. PMID: 39846165
Epub:
Not Epub
Abstract:
Background: Sprouting blood vessels, reaching the aimed location, and establishing the proper connections are vital for...
Link:
https://www.ahajournals.org/doi/10.1161/ATVBAHA.124.321588
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu X, Wang X, Li B, Wang X, Duan X, Liu D. Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebra Fish. Arterioscler Thromb Vasc Biol. 2025 Jan 23. doi: 10.1161/ATVBAHA.124.321588. Epub ahead of print. PMID: 39846165.

Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition

Authors:
Deebani A, Mary J, Dhinoja S, Al Qaryoute A, Fallatah W, Jagadeeswaran P
Citation:
Sci Rep. 2025 Jan 24;15(1):3058. doi: 10.1038/s41598-025-87117-1. PMID: 39856164; PMCID: PMC11761473
Epub:
Not Epub
Abstract:
Transmembrane proteins (TMEMs) are embedded in cell membranes and often have poorly understood functions. Our RNAseq analysis...
Link:
https://www.nature.com/articles/s41598-025-87117-1
Delivery Method:
Vivo-Morpholino piggyback hybrid; intravenous (i.v.)
Organism or Cell Type:
zebrafish
Citation Extract:
Deebani A, Mary J, Dhinoja S, Al Qaryoute A, Fallatah W, Jagadeeswaran P. Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition. Sci Rep. 2025 Jan 24;15(1):3058. doi: 10.1038/s41598-025-87117-1. PMID: 39856164; PMCID: PMC11761473.

Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2

Authors:
Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA
Citation:
bioRxiv [preprint] 2025.01.21.634176; doi: https://doi.org/10.1101/2025.01.21.634176
Epub:
Not Epub
Abstract:
Extracellular signals regulate epithelial homeostasis, cell fate and pattern cell behaviors during embryogenesis, wound healing...
Link:
https://www.biorxiv.org/content/10.1101/2025.01.21.634176v2.full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA. Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2. bioRxiv [preprint] 2025.01.21.634176; doi: https://doi.org/10.1101/2025.01.21.634176.

PRMT1-methylated MSX1 phase separates to control palate development

Authors:
Meng L, Jiang Y, You J, Chen Y, Guo S, Chen L, Ma J
Citation:
Nat Commun. 2025 Jan 22;16(1):949. doi: 10.1038/s41467-025-56327-6. PMID: 39843447; PMCID: PMC11754605
Epub:
Not Epub
Abstract:
Little is known about the regulation and function of phase separation in craniofacial developmental disorders. MSX1 mutations...
Link:
https://www.nature.com/articles/s41467-025-56327-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meng L, Jiang Y, You J, Chen Y, Guo S, Chen L, Ma J. PRMT1-methylated MSX1 phase separates to control palate development. Nat Commun. 2025 Jan 22;16(1):949. doi: 10.1038/s41467-025-56327-6. PMID: 39843447; PMCID: PMC11754605.

Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel-Like Structures in Hydrogels for Tissue Engineering

Authors:
Patra C, Rayrikar A, Wagh G, Kleefeldt F, Roshanbinfar K, Cop F, Nikolic I, Schmidt MHH, Acker-Palmer A, Ergün S, Engel FB
Citation:
J Am Heart Assoc. 2025 Jan 23:e037943. doi: 10.1161/JAHA.123.037943. Epub ahead of print. PMID: 39846290
Epub:
Not Epub
Abstract:
Background: Organs and tissues need to be vascularized during development. Similarly, vascularization is required to engineer...
Link:
https://www.ahajournals.org/doi/10.1161/JAHA.123.037943
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patra C, Rayrikar A, Wagh G, Kleefeldt F, Roshanbinfar K, Cop F, Nikolic I, Schmidt MHH, Acker-Palmer A, Ergün S, Engel FB. Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel-Like Structures in Hydrogels for Tissue Engineering. J Am Heart Assoc. 2025 Jan 23:e037943. doi: 10.1161/JAHA.123.037943. Epub ahead of print. PMID: 39846290.

Dual role of Xenopus Odf2 in multiciliated cell patterning and differentiation

Authors:
Nommick A, Chuyen A, Clément R, Thomé V, Daian F, Rosnet O, Richard F, Brouilly N, Loiseau E, Boutin C, Kodjabachian L
Citation:
Dev Biol. 2025 Apr;520:224-238. doi: 10.1016/j.ydbio.2025.01.014. Epub 2025 Jan 24. PMID: 39864486
Epub:
Not Epub
Abstract:
In developing tissues, the number, position, and differentiation of cells must be coordinately controlled to ensure the...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160625000260
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nommick A, Chuyen A, Clément R, Thomé V, Daian F, Rosnet O, Richard F, Brouilly N, Loiseau E, Boutin C, Kodjabachian L. Dual role of Xenopus Odf2 in multiciliated cell patterning and differentiation. Dev Biol. 2025 Apr;520:224-238. doi: 10.1016/j.ydbio.2025.01.014. Epub 2025 Jan 24. PMID: 39864486.

Zebrafish PEX1 Is Required for the Generation of GABAergic Neuron in p3 Domain

Authors:
Ryu JH, Kim M, Kim A, Ro H, Kim SH, Yeo SY
Citation:
Dev Reprod. 2024 Dec;28(4):129-139. doi: 10.12717/DR.2024.28.4.129. Epub 2024 Dec 31. PMID: 39845513; PMCID: PMC11750165
Epub:
Not Epub
Abstract:
Maintenance of neural progenitors requires Notch signaling in vertebrate development. Previous study has shown that Jagged2-...
Link:
https://www.ksdb.org/archive/view_article?pid=dr-28-4-129
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ryu JH, Kim M, Kim A, Ro H, Kim SH, Yeo SY. Zebrafish PEX1 Is Required for the Generation of GABAergic Neuron in p3 Domain. Dev Reprod. 2024 Dec;28(4):129-139. doi: 10.12717/DR.2024.28.4.129. Epub 2024 Dec 31. PMID: 39845513; PMCID: PMC11750165.

Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function

Authors:
Anderson CM, Kulkarni A, Maier B, Huang F, Figatner K, Chakraborty A, Pratuangtham S, May SC, Tersey SA, Anderson RM, Mirmira RG
Citation:
J Biol Chem. 2025 Jan 18:108209. doi: 10.1016/j.jbc.2025.108209. Epub ahead of print. PMID: 39832654
Epub:
Not Epub
Abstract:
Hypusination of eukaryotic translation initiation factor 5A (eIF5A) is essential for its role in translation elongation and...
Link:
https://linkinghub.elsevier.com/retrieve/pii/S0021925825000560
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson CM, Kulkarni A, Maier B, Huang F, Figatner K, Chakraborty A, Pratuangtham S, May SC, Tersey SA, Anderson RM, Mirmira RG. Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function. J Biol Chem. 2025 Jan 18:108209. doi: 10.1016/j.jbc.2025.108209. Epub ahead of print. PMID: 39832654.

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