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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Deficiency of copper responsive gene stmn4 induces retinal developmental defects

Authors:
Jing Y, Luo Y, Li L, Liu M, Liu JX
Citation:
Cell Biol Toxicol. 2024 Jan 22;40(1):2. doi: 10.1007/s10565-024-09847-8
Epub:
Not Epub
Abstract:
As part of the central nervous system (CNS), the retina senses light and also conducts and processes visual impulses. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jing Y, Luo Y, Li L, Liu M, Liu JX. Deficiency of copper responsive gene stmn4 induces retinal developmental defects. Cell Biol Toxicol. 2024 Jan 22;40(1):2. doi: 10.1007/s10565-024-09847-8.

The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio

Authors:
Partevian SA, Safina DR, Rudenok MM, Rybolovlev IN, Semenova EI, Shadrina MI, Slominsky PA, Kostrov SV, Alieva AKh
Citation:
Mol Gen Microbiol Virol. 2024;38:143-9. doi:10.3103/S0891416823030059
Epub:
Not Epub
Abstract:
The Annexin 2 protein (ANXA2) encoded by the ANXA2 gene performs a number of biological functions that are primarily related to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Partevian SA, Safina DR, Rudenok MM, Rybolovlev IN, Semenova EI, Shadrina MI, Slominsky PA, Kostrov SV, Alieva AKh. The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio. Mol Gen Microbiol Virol. 2024;38:143-9. doi:10.3103/S0891416823030059.

Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling

Authors:
Dogra D, Phan VA, Gavrilovici C, DiMarzo N, Ibhazehiebo K, Kurrasch DM
Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.15.575806
Epub:
Not Epub
Abstract:
SLC13A5 encodes a citrate transporter highly expressed in the brain important for regulating intra- and extracellular citrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dogra D, Phan VA, Gavrilovici C, DiMarzo N, Ibhazehiebo K, Kurrasch DM. Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling. bioRxiv. 2024;[preprint] doi:10.1101/2024.01.15.575806.

Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production

Authors:
Li Y, Li X, Ye D, Zhang R, Liu C, He M, Wang H, Hu W, Sun Y
Citation:
Zool Res. 2024 Jan 18;45(1):176-188. doi: 10.24272/j.issn.2095-8137.2023.032
Epub:
Not Epub
Abstract:
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly docosahexaenoic acid (22:6n-3, DHA), play crucial roles in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Li X, Ye D, Zhang R, Liu C, He M, Wang H, Hu W, Sun Y. Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production. Zool Res. 2024 Jan 18;45(1):176-188. doi: 10.24272/j.issn.2095-8137.2023.032.

Ciliary length regulation by intraflagellar transport in zebrafish

Authors:
Sun Y, Chen Z, Jin M, Xie H, Zhao C
Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.16.575975
Epub:
Not Epub
Abstract:
How cells regulate the size of their organelles remains a fundamental question in cell biology. Cilia, with their simple...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Chen Z, Jin M, Xie H, Zhao C. Ciliary length regulation by intraflagellar transport in zebrafish. bioRxiv. 2024;[preprint] doi:10.1101/2024.01.16.575975.

Dyrk1a is required for craniofacial development in Xenopus laevis

Authors:
Johnson HK, Wahl SE, Sesay F, Litovchick L, Dickinson AJ
Citation:
Dev Biol. 2024 Jul;511:63-75. doi: 10.1016/j.ydbio.2024.04.004. Epub 2024 Apr 15. PMID: 38621649
Epub:
Not Epub
Abstract:
Loss of function mutations in the dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) gene are associated...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Johnson HK, Wahl SE, Sesay F, Litovchick L, Dickinson AJ. Dyrk1a is required for craniofacial development in Xenopus laevis. Dev Biol. 2024 Jul;511:63-75. doi: 10.1016/j.ydbio.2024.04.004. Epub 2024 Apr 15. PMID: 38621649.

Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS)

Authors:
Hassett K, Potu SS, Sankaramoorthy A, Kaneshamoorthy S, Leka K, Huentelman MJ, Narayanan V, Rangasamy S
Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.09.574075
Epub:
Not Epub
Abstract:
Okur-Chung Neurodevelopmental Syndrome (OCNDS) is a rare, autosomal dominant disorder caused by heterozygous pathogenic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hassett K, Potu SS, Sankaramoorthy A, Kaneshamoorthy S, Leka K, Huentelman MJ, Narayanan V, Rangasamy S. Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS). bioRxiv. 2024;[preprint] doi:10.1101/2024.01.09.574075.

Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts

Authors:
Arslan FN, Hannezo É, Merrin J, Loose M, Heisenberg CP
Citation:
Curr Biol. 2024 Jan 8;34(1):171-182.e8. doi: 10.1016/j.cub.2023.11.067. Epub 2023 Dec 21
Epub:
Not Epub
Abstract:
Metazoan development relies on the formation and remodeling of cell-cell contacts. Dynamic reorganization of adhesion receptors...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arslan FN, Hannezo É, Merrin J, Loose M, Heisenberg CP. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. Curr Biol. 2024 Jan 8;34(1):171-182.e8. doi: 10.1016/j.cub.2023.11.067. Epub 2023 Dec 21.

amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway

Authors:
Sun L, Ping L, Fan X, Fan Y, Zhang B, Chen X
Citation:
Int J Mol Sci. 2024;25(2):734. doi:10.3390/ijms25020734
Epub:
Not Epub
Abstract:
Microtia-atresia is a rare type of congenital craniofacial malformation causing severe damage to the appearance and hearing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun L, Ping L, Fan X, Fan Y, Zhang B, Chen X. amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway. Int J Mol Sci. 2024;25(2):734. doi:10.3390/ijms25020734.

Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation

Authors:
Gerard A, Potocki L, Rosenfeld JA, Lalani SR, Scott TM, Scott D, Azamian MS, Louie R, Moore HW, Champaigne NL, Hollingsworth G, Torella A, Nigro V, Ploski R, Salpietro V, Zara F, Pizzi S, Chillemi G, Ognibene M, Cooney E, Do J, Linnemann A, Larsen MJ, Specht S, Walters KJ, Choi HJ, Choi M, Tartaglia M, Youkharibache P, Chae JH, Capra V, Park SG, Westlake CJ
Citation:
Nat Commun. 2024 Jan 8;15(1):365. doi: 10.1038/s41467-023-44611-2
Epub:
Not Epub
Abstract:
Accogli A, Shakya S, Yang T, Insinna C, Kim SY, Bell D, Butov KR, Severino M, Niceta M, Scala M, Lee HS, Yoo T, Stauffer J,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gerard A, Potocki L, Rosenfeld JA, Lalani SR, Scott TM, Scott D, Azamian MS, Louie R, Moore HW, Champaigne NL, Hollingsworth G, Torella A, Nigro V, Ploski R, Salpietro V, Zara F, Pizzi S, Chillemi G, Ognibene M, Cooney E, Do J, Linnemann A, Larsen MJ, Specht S, Walters KJ, Choi HJ, Choi M, Tartaglia M, Youkharibache P, Chae JH, Capra V, Park SG, Westlake CJ. Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation. Nat Commun. 2024 Jan 8;15(1):365. doi: 10.1038/s41467-023-44611-2.

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