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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12112 scientific papers returned from the database with the search filters currently being used below.

Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina

Authors:
Lyu P, Iribarne M, Serjanov D, Zhai Y, Hoang T, Campbell LJ, Boyd P, Palazzo I, Nagashima M, Silva NJ, Hitchcock PF, Qian J, Hyde DR, Blackshaw S
Citation:
Nat Commun. 2023 Dec 20;14(1):8477. doi: 10.1038/s41467-023-44142-w
Epub:
Not Epub
Abstract:
Following acute retinal damage, zebrafish possess the ability to regenerate all neuronal subtypes through Müller glia (MG)...
Delivery Method:
intravitreal injection & electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Lyu P, Iribarne M, Serjanov D, Zhai Y, Hoang T, Campbell LJ, Boyd P, Palazzo I, Nagashima M, Silva NJ, Hitchcock PF, Qian J, Hyde DR, Blackshaw S. Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina. Nat Commun. 2023 Dec 20;14(1):8477. doi: 10.1038/s41467-023-44142-w.

β-adrenergic receptor regulates embryonic epithelial extensibility through actomyosin inhibition

Authors:
Mizoguchi Y, Nakashima K, Sato A, Shindo A
Citation:
iScience. 2023 Nov 15;26(12):108469. doi: 10.1016/j.isci.2023.108469. eCollection 2023 Dec 15
Epub:
Not Epub
Abstract:
During morphogenesis, epithelial tissues reshape and expand to cover the body and organs. The molecular mechanisms of this...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mizoguchi Y, Nakashima K, Sato A, Shindo A. β-adrenergic receptor regulates embryonic epithelial extensibility through actomyosin inhibition. iScience. 2023 Nov 15;26(12):108469. doi: 10.1016/j.isci.2023.108469. eCollection 2023 Dec 15.

BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience in Xenopus laevis tadpoles

Authors:
Huang LC, McKeown CR, He HY, Ta AC, Cline HT
Citation:
Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2316542121. doi: 10.1073/pnas.2316542121. Epub 2024 Jan 10
Epub:
Not Epub
Abstract:
In developing Xenopus tadpoles, the optic tectum begins to receive patterned visual input while visuomotor circuits are still...
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Huang LC, McKeown CR, He HY, Ta AC, Cline HT. BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience in Xenopus laevis tadpoles. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2316542121. doi: 10.1073/pnas.2316542121. Epub 2024 Jan 10.

SH2 domain protein E and ABL signaling regulate blood vessel size

Authors:
Schumacher JA, Wright ZA, Rufin Florat D, Anand SK, Dasyani M, Batta SPR, Laverde V, Ferrari K, Klimkaite L, Bredemeier NO, Gurung S, Koller GM, Aguera KN, Chadwick GP, Johnson RD, Davis GE, Sumanas S
Citation:
PLoS Genet. 2024 Jan 8;20(1):e1010851. doi: 10.1371/journal.pgen.1010851. Online ahead of print
Epub:
Not Epub
Abstract:
Blood vessels in different vascular beds vary in size, which is essential for their function and fluid flow along the vascular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schumacher JA, Wright ZA, Rufin Florat D, Anand SK, Dasyani M, Batta SPR, Laverde V, Ferrari K, Klimkaite L, Bredemeier NO, Gurung S, Koller GM, Aguera KN, Chadwick GP, Johnson RD, Davis GE, Sumanas S. SH2 domain protein E and ABL signaling regulate blood vessel size. PLoS Genet. 2024 Jan 8;20(1):e1010851. doi: 10.1371/journal.pgen.1010851. Online ahead of print.

The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development

Authors:
Song X, Hu R, Chen Y, Xiao M, Zhang H, Wu S, Lu Q
Citation:
J Mol Cell Biol. 2024 Jan 4:mjad083. doi: 10.1093/jmcb/mjad083. Online ahead of print
Epub:
Yes
Abstract:
TRAF7 serves as a crucial intracellular adaptor and E3 ubiquitin ligase involved in signal transduction pathways, contributing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Song X, Hu R, Chen Y, Xiao M, Zhang H, Wu S, Lu Q. The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development. J Mol Cell Biol. 2024 Jan 4:mjad083. doi: 10.1093/jmcb/mjad083. Online ahead of print.

ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation

Authors:
Wang C, Liu Z, Zeng Y, Zhou L, Long Q, Hassan IU, Zhang Y, Qi X, Cai D, Mao B, Lu G, Sun J, Yao Y, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H
Citation:
EMBO Rep. 2024 Jan 2. doi: 10.1038/s44319-023-00046-w. Online ahead of print
Epub:
Yes
Abstract:
The dorsoventral gradient of BMP signaling plays an essential role in embryonic patterning. Zinc Finger SWIM-Type Containing 4...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Wang C, Liu Z, Zeng Y, Zhou L, Long Q, Hassan IU, Zhang Y, Qi X, Cai D, Mao B, Lu G, Sun J, Yao Y, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H. ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation. EMBO Rep. 2024 Jan 2. doi: 10.1038/s44319-023-00046-w. Online ahead of print.

CLN3 deficiency leads to neurological and metabolic perturbations during early development

Authors:
Heins-Marroquin U, Singh RR, Perathoner S, Gavotto F, Merino Ruiz C, Patraskaki M, Gomez-Giro G, Kleine Borgmann F, Meyer M, Carpentier A, Warmoes MO, Jäger C, Mittelbronn M, Schwamborn JC, Cordero-Maldonado ML, Crawford AD, Schymanski EL, Linster CL
Citation:
Life Sci Alliance. 2024 Jan 9;7(3):e202302057 doi: 10.26508/lsa.202302057. Print 2024 Mar
Epub:
Not Epub
Abstract:
Juvenile neuronal ceroid lipofuscinosis (or Batten disease) is an autosomal recessive, rare neurodegenerative disorder that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heins-Marroquin U, Singh RR, Perathoner S, Gavotto F, Merino Ruiz C, Patraskaki M, Gomez-Giro G, Kleine Borgmann F, Meyer M, Carpentier A, Warmoes MO, Jäger C, Mittelbronn M, Schwamborn JC, Cordero-Maldonado ML, Crawford AD, Schymanski EL, Linster CL. CLN3 deficiency leads to neurological and metabolic perturbations during early development . Life Sci Alliance. 2024 Jan 9;7(3):e202302057 doi: 10.26508/lsa.202302057. Print 2024 Mar.

Identification of End-Binding 1 Protein as Novel α-4 Giardin-Binding Partners in Giardia lamblia Trophozoites

Authors:
Zhang K, Shen H, Wang Y, Shen H, Zhang C, Zou X, Yu Y, Tian X, Wang Y
Citation:
Acta Parasitol. 2024 Jan 11. doi: 10.1007/s11686-023-00774-y. Online ahead of print
Epub:
Yes
Abstract:
Background: Giardia lamblia (syn. G. intestinalis, G. duodenalis) is a primitive opportunistic protozoon, and one of the...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Zhang K, Shen H, Wang Y, Shen H, Zhang C, Zou X, Yu Y, Tian X, Wang Y. Identification of End-Binding 1 Protein as Novel α-4 Giardin-Binding Partners in Giardia lamblia Trophozoites. Acta Parasitol. 2024 Jan 11. doi: 10.1007/s11686-023-00774-y. Online ahead of print.

Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway

Authors:
Hu W, Chen G, Yuan W, Guo C, Liu F, Zhang S, Cao Z
Citation:
Ecotoxicol Environ Saf. 2024 Jan 4;270:115911. doi: 10.1016/j.ecoenv.2023.115911. Online ahead of print
Epub:
Not Epub
Abstract:
Iprodione is an effective and broad-spectrum fungicide commonly used for early disease control in fruit trees and vegetables....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu W, Chen G, Yuan W, Guo C, Liu F, Zhang S, Cao Z. Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway. Ecotoxicol Environ Saf. 2024 Jan 4;270:115911. doi: 10.1016/j.ecoenv.2023.115911. Online ahead of print.

Damage-induced basal epithelial cell migration modulates the spatial organization of redox signaling and sensory neuron regeneration

Authors:
Fister AM, Horn A, Lasarev M, Huttenlocher A
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.14.532628
Epub:
Not Epub
Abstract:
Epithelial damage leads to early reactive oxygen species (ROS) signaling, which regulates sensory neuron regeneration and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fister AM, Horn A, Lasarev M, Huttenlocher A. Damage-induced basal epithelial cell migration modulates the spatial organization of redox signaling and sensory neuron regeneration. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.14.532628 .

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