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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus
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Citation:
Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179 Epub:
Not Epub Abstract:
The basal chordate amphioxus resembles vertebrates in having a dorsal, hollow nerve cord, a notochord and somites. However, it... Delivery Method:
microinjection Organism or Cell Type:
Branchiostoma floridae (amphioxis) Citation Extract: Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ. Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179. |
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling
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Citation:
Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230 Epub:
Not Epub Abstract:
Wnts are secreted ligands that activate several receptor-mediated signal transduction cascades. Homeostatic Wnt signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT
. Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. |
Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish
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Citation:
Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187 Epub:
Not Epub Abstract:
Orchestrated protein synthesis and degradation is fundamental for proper cell function. In muscle, impairment of proteostasis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187. |
mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration
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Citation:
Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar Epub:
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Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function... Delivery Method:
peptide-linked Organism or Cell Type:
mice, mdx Citation Extract: Roberts TC, Blomberg KE, Smith CI, El Andaloussi S, Wood MJ. mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration. Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar. |
A ligand-independent integrin β1 mechanosensory complex guides spindle orientation
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Citation:
Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899 Epub:
Not Epub Abstract:
Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Petridou NI, Skourides PA. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899. |
The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity
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Citation:
J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22 Epub:
Not Epub Abstract:
Cranial neural crest (CNC) cells are a transient population of stem cells that originate at the border of the neural plate and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Abbruzzese G, Gorny AK, Kaufmann LT, Cousin H, Kleino I, Steinbeisser H, Alfandari D. The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity. J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22. |
Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology
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Citation:
J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502 Epub:
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Cilia-driven fluid flow is a critical yet poorly understood aspect of pulmonary physiology. Here, we demonstrate that optical... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, zebrafish Citation Extract: Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA. Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology. J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502. |
β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner
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Citation:
Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2016.03.012 Epub:
Yes Abstract:
Amyloid precursor protein (APP) is a transmembrane glycoprotein that has been the subject of intense research because of its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Banote RK, Edling M, Eliassen F, Kettunen P, Zetterberg H, Abramsson A. β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner. Dev Biol. 2016;[Epub ahead of print] doi:10.1016/j.ydbio.2016.03.012. |
Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis
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Citation:
JCI Insight. 2016;1(3):e85461. doi:10.1172/jci.insight.85461 Epub:
Not Epub Abstract:
The 2p15p16.1 microdeletion syndrome has a core phenotype consisting of intellectual disability, microcephaly, hypotonia,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bagheri H, Badduke C, Qiao Y, Colnaghi R, Abramowicz I, Alcantara D, Dunham C, Wen J, Wildin RS, Nowaczyk MJM, Eichmeyer J, Lehman A, Maranda B, Martell S, Shan X, Lewis SME, O’Driscoll M, Gregory-Evans CY, Rajcan-Separovic E. Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis. JCI Insight. 2016;1(3):e85461. doi:10.1172/jci.insight.85461. |
Evolution of gene regulatory network topology and dorsal-1 ventral axis specification in early development of sea urchins (Echinoidea)
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Citation:
bioRxiv. 2016. doi:10.1101/044149 Epub:
Yes Abstract:
Developmental gene regulatory networks (dGRNs) are assemblages of interacting regulatory factors that direct ontogeny of animal... Delivery Method:
microinjection Organism or Cell Type:
Eucidaris tribuloides (sea urchin) Citation Extract: Erkenbrack EM. Evolution of gene regulatory network topology and dorsal-1 ventral axis specification in early development of sea urchins (Echinoidea). bioRxiv. 2016. doi:10.1101/044149. |