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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro

Authors:
Sato Y, Sato S, Kikuchi T, Nonaka A, Kumagaia Y, Sasaki A, Kobayashi M
Citation:
Anal Biochem. 2016;209:41-5. doi:10.1016/j.ab.2016.06.032
Epub:
Yes
Abstract:
Knockdown of gene expression by antisense morpholino oligos (MOs) is a simple and effective method for analyzing the roles of...
Link:
http://www.sciencedirect.com/science/article/pii/S0003269716301671
Delivery Method:
Endo-Porter
Organism or Cell Type:
preimplantation mouse embryo
Citation Extract:
Sato Y, Sato S, Kikuchi T, Nonaka A, Kumagaia Y, Sasaki A, Kobayashi M. Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro. Anal Biochem. 2016;209:41-5. doi:10.1016/j.ab.2016.06.032.

Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis

Authors:
Liu H-H, Cline HT
Citation:
J Neurosci. 2016;36(27):7325-7339. doi:10.1523/JNEUROSCI.4282-15.2016
Epub:
Not Epub
Abstract:
Fragile X mental retardation protein (FMRP) is thought to regulate neuronal plasticity by limiting dendritic protein synthesis...
Link:
http://www.jneurosci.org/content/36/27/7325.abstract
Organism or Cell Type:
Xenopus
Citation Extract:
Liu H-H, Cline HT. Fragile X Mental Retardation Protein Is Required to Maintain Visual Conditioning-Induced Behavioral Plasticity by Limiting Local Protein Synthesis. J Neurosci. 2016;36(27):7325-7339. doi:10.1523/JNEUROSCI.4282-15.2016.

Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explants

Authors:
Wallkamm V, Rahm K, Schmoll J, Kaufmann LT, Brinkmann E, Schunk J, Kraft B, Wedlich D, Gradl D
Citation:
BMC Biology. 2016;14:55. doi:10.1186/s12915-016-0278-x
Epub:
Not Epub
Abstract:
Background: A tight regulation of the Wnt-signaling network, activated by 19 Wnt molecules and numerous receptors and co-...
Link:
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0278-x
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Wallkamm V, Rahm K, Schmoll J, Kaufmann LT, Brinkmann E, Schunk J, Kraft B, Wedlich D, Gradl D. Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explants. BMC Biology. 2016;14:55. doi:10.1186/s12915-016-0278-x.

Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent

Authors:
Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, Le Moigne V, Vilchèze C, Guérardel Y, Lutfalla G, Herrmann J-L, Jacobs WR Jr, Kremer L
Citation:
PNAS. 2016;[Epub ahead of print] doi:10.1073/pnas.1605477113
Epub:
Yes
Abstract:
Mycobacterium abscessus (Mabs) is a rapidly growing Mycobacterium and an emerging pathogen in humans. Transitioning from a...
Link:
http://www.pnas.org/content/early/2016/07/05/1605477113.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, Le Moigne V, Vilchèze C, Guérardel Y, Lutfalla G, Herrmann J-L, Jacobs WR Jr, Kremer L. Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent. PNAS. 2016;[Epub ahead of print] doi:10.1073/pnas.1605477113 .

Increasing the Detection Sensitivity for DNA-Morpholino Hybridization in Sub-Nanomolar Regime by Enhancing the Surface Ion Conductance of PEDOT:PSS Membrane in a Microchannel

Authors:
Wei X, Panindre P, Zhang Q, Song Y-A
Citation:
ACS Sens. 2016;[Epub ahead ofprint] doi:10.1021/acssensors.6b00169
Epub:
Yes
Abstract:
Electrokinetic concentration based on ion concentration polarization (ICP) offers a unique possibility to increase detection...
Link:
http://pubs.acs.org/doi/abs/10.1021/acssensors.6b00169
Citation Extract:
Wei X, Panindre P, Zhang Q, Song Y-A. Increasing the Detection Sensitivity for DNA-Morpholino Hybridization in Sub-Nanomolar Regime by Enhancing the Surface Ion Conductance of PEDOT:PSS Membrane in a Microchannel. ACS Sens. 2016;[Epub ahead ofprint] doi:10.1021/acssensors.6b00169.

Antisense pre-treatment increases gene therapy efficacy in dystrophic muscles

Authors:
Peccate C, Mollard A, Le Hir M, Julien L, McClorey G, Jarmin S, Le Heron A, Dickson G, Benkhelifa-Ziyyat S, Piétri-Rouxel F, Wood MJ, Voit T, Lorain S
Citation:
Hum Mol Genet. 2016 Jul 4. pii: ddw201. [Epub ahead of print]
Epub:
Yes
Abstract:
In preclinical models for Duchenne muscular dystrophy, dystrophin restoration during AAV-U7-mediated exon-skipping therapy was...
Link:
http://hmg.oxfordjournals.org/content/early/2016/07/03/hmg.ddw201.abstract
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Peccate C, Mollard A, Le Hir M, Julien L, McClorey G, Jarmin S, Le Heron A, Dickson G, Benkhelifa-Ziyyat S, Piétri-Rouxel F, Wood MJ, Voit T, Lorain S. Antisense pre-treatment increases gene therapy efficacy in dystrophic muscles. Hum Mol Genet. 2016 Jul 4. pii: ddw201. [Epub ahead of print].

Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis

Authors:
Fujii T, Tsunesumi SI, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, Watanabe S
Citation:
Sci Rep. 2016 Jul 5;6:29157. doi: 10.1038/srep29157
Epub:
Not Epub
Abstract:
Methylation of histone tails plays a pivotal role in the regulation of a wide range of biological processes. SET and MYND...
Link:
http://www.nature.com/articles/srep29157
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fujii T, Tsunesumi SI, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, Watanabe S. Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Sci Rep. 2016 Jul 5;6:29157. doi: 10.1038/srep29157.

Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy

Authors:
Catapano F, Zaharieva I, Scoto M, Marrosu E, Morgan J, Muntoni F, Zhou H
Citation:
Mol Ther Nucleic Acids. 2016 Jul 5;5(7):e331. doi: 10.1038/mtna.2016.47
Epub:
Not Epub
Abstract:
The identification of noninvasive biomarkers to monitor the disease progression in spinal muscular atrophy (SMA) is becoming...
Link:
http://www.nature.com/mtna/journal/v5/n7/full/mtna201647a.html
Delivery Method:
injection
Organism or Cell Type:
mice
Citation Extract:
Catapano F, Zaharieva I, Scoto M, Marrosu E, Morgan J, Muntoni F, Zhou H. Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy. Mol Ther Nucleic Acids. 2016 Jul 5;5(7):e331. doi: 10.1038/mtna.2016.47.

Tbx16 regulates hox gene activation in mesodermal progenitor cells

Authors:
Payumo AY, McQuade LE, Walker WJ, Yamazoe S, Chen JK
Citation:
Nat Chem Biol. 2016 Jul 4. doi: 10.1038/nchembio.2124. [Epub ahead of print]
Epub:
Yes
Abstract:
The transcription factor T-box 16 (Tbx16, or Spadetail) is an essential regulator of paraxial mesoderm development in zebrafish...
Link:
http://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.2124.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Payumo AY, McQuade LE, Walker WJ, Yamazoe S, Chen JK. Tbx16 regulates hox gene activation in mesodermal progenitor cells. Nat Chem Biol. 2016 Jul 4. doi: 10.1038/nchembio.2124. [Epub ahead of print].

NFAT5-mediated CACNA1C expression is critical for cardiac electrophysiological development and maturation

Authors:
Li W, Zheng NZ, Yuan Q, Xu K, Yang F, Gu L, Zheng GY, Luo GJ, Fan C, Ji GJ, Zhang B, Cao H, Tian XL
Citation:
J Mol Med (Berl). 2016 Jul 1. [Epub ahead of print]
Epub:
Yes
Abstract:
Entry of calcium into cardiomyocyte via L-type calcium channel (LTCC) is fundamental to cardiac contraction. CACNA1C, a type of...
Link:
http://link.springer.com/article/10.1007%2Fs00109-016-1444-x
Organism or Cell Type:
zebrafish
Citation Extract:
Li W, Zheng NZ, Yuan Q, Xu K, Yang F, Gu L, Zheng GY, Luo GJ, Fan C, Ji GJ, Zhang B, Cao H, Tian XL. NFAT5-mediated CACNA1C expression is critical for cardiac electrophysiological development and maturation. J Mol Med (Berl). 2016 Jul 1. [Epub ahead of print].

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