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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

A Clearance Step will become Increasingly Crucial for Pretargeted Tumor Therapy when Tumor Accumulation is Improved

Authors:
Liu G
Citation:
J Cancer Clin Trials. 2016;1:106. doi:10.4172/jcct.1000106
Epub:
Not Epub
Abstract:
This is a commentary on a paper we published in Cancer Biother Radiopharm 2010. This commentary addresses related concerns...
Citation Extract:
Liu G. A Clearance Step will become Increasingly Crucial for Pretargeted Tumor Therapy when Tumor Accumulation is Improved. J Cancer Clin Trials. 2016;1:106. doi:10.4172/jcct.1000106.

Cadherin-11 localizes to focal adhesions and promotes cell–substrate adhesion

Authors:
Langhe RP, Gudzenko T, Bachmann M, Becker SF, Gonnermann C, Winter C, Abbruzzese G, Alfandari D, Kratzer M-C, Franz CM, Kashef J
Citation:
Nat Comm. 2016;7:10909. doi:10.1038/ncomms10909
Epub:
Not Epub
Abstract:
Cadherin receptors have a well-established role in cell–cell adhesion, cell polarization and differentiation. However, some...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Langhe RP, Gudzenko T, Bachmann M, Becker SF, Gonnermann C, Winter C, Abbruzzese G, Alfandari D, Kratzer M-C, Franz CM, Kashef J. Cadherin-11 localizes to focal adhesions and promotes cell–substrate adhesion. Nat Comm. 2016;7:10909. doi:10.1038/ncomms10909.

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

Authors:
Hirth S, Bühler A, Bührdel JB, Rudeck S, Dahme T, Rottbauer W, Just S
Citation:
PLoS ONE. 2016;11(3):e0150323. doi:10.1371/journal.pone.0150323
Epub:
Not Epub
Abstract:
An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hirth S, Bühler A, Bührdel JB, Rudeck S, Dahme T, Rottbauer W, Just S. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11(3):e0150323. doi:10.1371/journal.pone.0150323.

pdzrn3 is required for pronephros morphogenesis in Xenopus laevis

Authors:
Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L
Citation:
Int J Dev Biol. 2016 Mar 2. [Epub ahead of print]
Epub:
Yes
Abstract:
Pdzrn3, a multidomain protein with E3-ubiquitin ligase activity, has been reported to play a role in myoblast and osteoblast...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L. pdzrn3 is required for pronephros morphogenesis in Xenopus laevis. Int J Dev Biol. 2016 Mar 2. [Epub ahead of print].

Halogenated carbazoles induce cardiotoxicity in developing zebrafish embryos (Danio rerio)

Authors:
Fang M, Guo J, Chen D, Li A, Hinton DE, Dong W
Citation:
Environ Toxicol Chem. 2016 Mar 2. doi: 10.1002/etc.3416. [Epub ahead of print]
Epub:
Yes
Abstract:
Halogenated carbazoles are increasingly identified as a novel class of environmental contaminants. However, no in vivo acute...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fang M, Guo J, Chen D, Li A, Hinton DE, Dong W. Halogenated carbazoles induce cardiotoxicity in developing zebrafish embryos (Danio rerio). Environ Toxicol Chem. 2016 Mar 2. doi: 10.1002/etc.3416. [Epub ahead of print].

The Lhx9-Integrin pathway is essential for positioning of the proepicardial organ

Authors:
Tandon P, Wilczewski CM, Williams CE, Conlon FL
Citation:
Development. 2016 Jan 25. pii: dev.129551. [Epub ahead of print]
Epub:
Yes
Abstract:
The development of the vertebrate embryonic heart occurs by hyperplastic growth as well as the incorporation of cells from...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tandon P, Wilczewski CM, Williams CE, Conlon FL. The Lhx9-Integrin pathway is essential for positioning of the proepicardial organ. Development. 2016 Jan 25. pii: dev.129551. [Epub ahead of print].

Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement

Authors:
Verstraeten B, van Hengel J, Huysseune A
Citation:
PLoS ONE. 2016;11(3):e0148114. doi:10.1371/journal.pone.0148114
Epub:
Not Epub
Abstract:
We analyzed the protein distribution of two cadherin-associated molecules, plakoglobin and β-catenin, during the different...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Verstraeten B, van Hengel J, Huysseune A . Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement. PLoS ONE. 2016;11(3):e0148114. doi:10.1371/journal.pone.0148114.

Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy

Authors:
Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung MY
Citation:
Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print]
Epub:
Yes
Abstract:
Familial exudative vitreoretinopathy (FEVR) belongs to a group of genetically and clinically heterogeneous disorders in retinal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung MY. Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy. Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print].

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

Authors:
Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH
Citation:
Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666
Epub:
Not Epub
Abstract:
The Src family kinase (SFK) member SRC is a major target in drug development because it is activated in many human cancers, yet...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666.

Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy

Authors:
Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L
Citation:
Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print]
Epub:
Yes
Abstract:
Mitochondria are the site of iron utilization, wherein imported iron is incorporated into heme or iron-sulfur clusters....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L. Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print].

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