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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function
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Citation:
Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):2942-54. doi: 10.1167/iovs.15-18996 Epub:
Not Epub Abstract:
PURPOSE: Tail-anchored (TA) proteins contain a single hydrophobic domain at the C-terminus and are posttranslationally inserted... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Daniele LL, Emran F, Lobo GP, Gaivin RJ, Perkins BD. Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function. Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):2942-54. doi: 10.1167/iovs.15-18996. |
Leptospiral outer membrane protein LipL32 induces inflammation and kidney injury in zebrafish larvae
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Citation:
Sci Rep. 2016;6:27838. doi:10.1038/srep27838 Epub:
Not Epub Abstract:
Leptospirosis is an often overlooked cause of acute kidney injury that can lead to multiple organ failure and even death. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chang M-Y, Cheng Y-C, Hsu S-H, Ma T-L, Chou L-F, Hsu H-H, Tian Y-C, Chen Y-C, Sun Y-J, Hung C-C, Pan R-L, Yang C-W. Leptospiral outer membrane protein LipL32 induces inflammation and kidney injury in zebrafish larvae. Sci Rep. 2016;6:27838. doi:10.1038/srep27838. |
An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN
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Citation:
npj Genomic Med. 2016;1:16016. doi:10.1038/npjgenmed.2016.16 Epub:
Not Epub Abstract:
Targeted next-generation sequencing (NGS) identified a novel loss of function mutation in GARS, a gene linked to Charcot–Marie–... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holloway MP, DeNardo BD, Phornphutkul C, Nguyen K, Davis C, Jackson C, Richendrfer H, Creton R, Altura RA. An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN. npj Genomic Med. 2016;1:16016. doi:10.1038/npjgenmed.2016.16. |
LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation
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Citation:
J Neurosci Res. 2016 Jun 5. doi: 10.1002/jnr.23754. [Epub ahead of print] Epub:
Yes Abstract:
Although mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common cause of genetic Parkinson's... Organism or Cell Type:
zebrafish Citation Extract: Prabhudesai S, Bensabeur FZ, Abdullah R, Basak I, Baez S, Alves G, Holtzman NG, Larsen JP, Møller SG. LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation. J Neurosci Res. 2016 Jun 5. doi: 10.1002/jnr.23754. [Epub ahead of print]. |
Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins
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Citation:
Genetics. 2016 Apr 2. pii: genetics.115.180943. [Epub ahead of print] Epub:
Not Epub Abstract:
Transport of proteins in the ciliary shaft is driven by microtubule-dependent motors, kinesins. Prior studies suggested that... Organism or Cell Type:
zebrafish Citation Extract: Pooranachandran N, Malicki JJ. Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins. Genetics. 2016 Apr 2. pii: genetics.115.180943. [Epub ahead of print]. |
Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish
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Citation:
Sci Rep. 2016;6:27470. doi:10.1038/srep27470 Epub:
Not Epub Abstract:
An unresolved mystery in the field of spinal muscular atrophy (SMA) is why a reduction of the ubiquitously expressed Smn... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Spiró Z, Koh A, Tay S, See K, Winkler C. Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish. Sci Rep. 2016;6:27470. doi:10.1038/srep27470. |
Identification of mutations in the MYO9A gene in patients with congenital myasthenic syndrome
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Citation:
Brain. 2016 Jun 3. pii: aww130. [Epub ahead of print] doi:10.1093/brain/aww130 Epub:
Not Epub Abstract:
Congenital myasthenic syndromes are a group of rare and genetically heterogenous disorders resulting from defects in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: O'Connor E, Töpf A, Müller JS, Cox D, Evangelista T, Colomer J, Abicht A, Senderek J, Hasselmann O, Yaramis A, Laval SH, Lochmüller H. Identification of mutations in the MYO9A gene in patients with congenital myasthenic syndrome. Brain. 2016 Jun 3. pii: aww130. [Epub ahead of print] doi:10.1093/brain/aww130. |
Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts
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Citation:
Nature. 2012 Nov 22;491(7425):608-12. doi: 10.1038/nature11536. Epub 2012 Nov 7. Erratum in: Nature. 2013 Apr 18;496(7445):386 Epub:
Not Epub Abstract:
Defects in the availability of heme substrates or the catalytic activity of the terminal enzyme in heme biosynthesis,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 2012 Nov 22;491(7425):608-12. doi: 10.1038/nature11536. Epub 2012 Nov 7. Erratum in: Nature. 2013 Apr 18;496(7445):386. |
Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness
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Citation:
Am J Hum Genet. 2016;98(6):1266-70. doi:10.1016/j.ajhg.2016.04.015 Epub:
Not Epub Abstract:
By genetic linkage analysis in a large consanguineous Iranian family with eleven individuals affected by severe to profound... Organism or Cell Type:
zebrafish Citation Extract: Delmaghani S, Aghaie A, Bouyacoub Y, El Hachmi H, Bonnet C, Riahi Z, Chardenoux S, Perfettini I, Hardelin J-P, Houmeida A, Herbomel P, Petit C. Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. Am J Hum Genet. 2016;98(6):1266-70. doi:10.1016/j.ajhg.2016.04.015. |
Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis
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Citation:
Sci Rep. 2016 May 31;6:27050. doi: 10.1038/srep27050 Epub:
Not Epub Abstract:
Lysophosphatidic acid (LPA), a growth factor-like phospholipid, regulates numerous physiological functions, including cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin KH, Ho YH, Chiang JC, Li MW, Lin SH, Chen WM, Chiang CL, Lin YN, Yang YJ, Chen CN, Lu J, Huang CJ, Tigyi G, Yao CL, Lee H. Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis. Sci Rep. 2016 May 31;6:27050. doi: 10.1038/srep27050. |