You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm
|
Citation:
Sci Rep. 2016;6:21538 doi:10.1038/srep21538 Epub:
Not Epub Abstract:
MOG1 was initially identified as a protein that interacts with the small GTPase Ran involved in transport of macromolecules... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhou J, Wang L, Zuo M, Wang X, Ahmed ASI, Chen Q, Wang QK. Cardiac sodium channel regulator MOG1 regulates cardiac morphogenesis and rhythm. Sci Rep. 2016;6:21538 doi:10.1038/srep21538. |
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
|
Citation:
Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw112 Epub:
Yes Abstract:
Phosphorothioate (PS)-modified antisense oligonucleotides (ASOs) have been extensively investigated over the past three decades... Delivery Method:
cell bathing Organism or Cell Type:
cell culture: Stabilin cell lines Citation Extract: Miller CM, Donner AJ, Blank EE, Egger AW, Kellar BM, Østergaard ME, Seth PP, Harris EN. Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver. Nucl Acids Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw112. |
Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish
|
Citation:
PLoS Genet. 2016;12(2):e1005881. doi:10.1371/journal.pgen.1005881 Epub:
Not Epub Abstract:
Unlike mammals and birds, teleost fish undergo external embryogenesis, and therefore their embryos are constantly challenged by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu M, Bai Y, Zhang C, Liu F, Cui Z, Chen J, Peng J. Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish. PLoS Genet. 2016;12(2):e1005881. doi:10.1371/journal.pgen.1005881. |
Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques
|
Citation:
PLoS Negl Trop Dis. 2016;10(2):e0004456. doi:10.1371/journal.pntd.0004456 Epub:
Not Epub Abstract:
Marburg virus (MARV) is an Ebola-like virus in the family Filovirdae that causes sporadic outbreaks of severe hemorrhagic fever... Delivery Method:
bolus iv injection Organism or Cell Type:
Macaca fascicularis (cynomolgus macaques) Citation Extract: Warren TK, Whitehouse CA, Wells J, Welch L, Charleston JS, Heald A, Nichols DK, Mattix ME, Palacios G, Kugleman JR, Iversen PI, Bavari S. Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques. PLoS Negl Trop Dis. 2016;10(2):e0004456. doi:10.1371/journal.pntd.0004456. |
Dynamin Binding Protein (Tuba) deficiency inhibits ciliogenesis and nephrogenesis in vitro and in vivo
|
Citation:
J Biol Chem. 2016 Feb 19. pii: jbc.M115.688663. [Epub ahead of print] Epub:
Not Epub Abstract:
Dysfunction of renal primary cilia leads to polycystic kidney disease (PKD). We previously showed that the exocyst, a protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Baek JI, Kwon SH, Zuo X, Kwon SY, Kim SH, Lipschutz JH. Dynamin Binding Protein (Tuba) deficiency inhibits ciliogenesis and nephrogenesis in vitro and in vivo. J Biol Chem. 2016 Feb 19. pii: jbc.M115.688663. [Epub ahead of print]. |
E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation
|
Citation:
Dev Cell. 2015 Feb 9;32(3):345-57. doi: 10.1016/j.devcel.2014.11.034 Epub:
Not Epub Abstract:
Transcription factor complexes have varied effects on cell fate and behavior, but how this diversification of function occurs... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Wills AE, Baker JC. E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation. Dev Cell. 2015 Feb 9;32(3):345-57. doi: 10.1016/j.devcel.2014.11.034. |
The Etv2-miR-130a Network Regulates Mesodermal Specification
|
Citation:
Cell Rep. 2015 Nov 3;13(5):915-23. doi: 10.1016/j.celrep.2015.09.060. Epub 2015 Oct 22 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) are known to regulate critical developmental stages during embryogenesis. Here, we defined an Etv2-miR-130a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Singh BN, Kawakami Y, Akiyama R, Rasmussen TL, Garry MG, Gong W, Das S, Shi X, Koyano-Nakagawa N, Garry DJ. The Etv2-miR-130a Network Regulates Mesodermal Specification. Cell Rep. 2015 Nov 3;13(5):915-23. doi: 10.1016/j.celrep.2015.09.060. Epub 2015 Oct 22. |
Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration
|
Citation:
PLoS Genet. 2016 Feb 4;12(2):e1005831. doi: 10.1371/journal.pgen.1005831. eCollection 2016 Feb Epub:
Not Epub Abstract:
The liver and pancreas originate from overlapping embryonic regions, and single-cell lineage tracing in zebrafish has shown... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu J, Cui J, Del Campo A, Shin CH. Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration. PLoS Genet. 2016 Feb 4;12(2):e1005831. doi: 10.1371/journal.pgen.1005831. eCollection 2016 Feb. |
Identification of cis-suppression of human disease mutations by comparative genomics
|
Citation:
Nature. 2015 Aug 13;524(7564):225-9. doi: 10.1038/nature14497. Epub 2015 Jun 29 Epub:
Not Epub Abstract:
Patterns of amino acid conservation have served as a tool for understanding protein evolution. The same principles have also... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jordan DM, Frangakis SG, Golzio C, Cassa CA, Kurtzberg J; Task Force for Neonatal Genomics, Davis EE, Sunyaev SR, Katsanis N. Identification of cis-suppression of human disease mutations by comparative genomics. Nature. 2015 Aug 13;524(7564):225-9. doi: 10.1038/nature14497. Epub 2015 Jun 29. |
Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism
|
Citation:
Neural Dev. 2016;11:5. doi:10.1186/s13064-016-0059-9 Epub:
Not Epub Abstract:
For neurons to function correctly in neuronal circuitry they must utilize appropriate neurotransmitters. However, even though... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Juárez-Morales JL, Schulte CJ, Pezoa SA, Vallejo GK, Hilinski WC, England SJ, de Jager S, Lewis KE. Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Dev. 2016;11:5. doi:10.1186/s13064-016-0059-9. |