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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
In vivo knockdown of basal forebrain p75 neurotrophin receptor stimulates choline acetyltransferase activity in the mature hippocampus
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Citation:
J Neurosci Res. 2016 Feb 11. doi: 10.1002/jnr.23717. [Epub ahead of print] Epub:
Yes Abstract:
This study seeks to determine whether knockdown of basal forebrain p75 neurotrophin receptor (p75NTR ) expression elicits... Delivery Method:
medial septa infusion Organism or Cell Type:
Rat Citation Extract: Barrett GL, Naim T, Trieu J, Huang M. In vivo knockdown of basal forebrain p75 neurotrophin receptor stimulates choline acetyltransferase activity in the mature hippocampus. J Neurosci Res. 2016 Feb 11. doi: 10.1002/jnr.23717. [Epub ahead of print]. |
Production of germ cell-deficient salmonids by dead end gene knockdown, and their use as recipients for germ cell transplantation
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Citation:
Mol Reprod Dev. 2016 Feb 9. doi: 10.1002/mrd.22625. [Epub ahead of print] Epub:
Yes Abstract:
We previously established a spermatogonial transplantation model in fish using triploid recipients. Although triploid salmonids... Delivery Method:
microinjection Organism or Cell Type:
Oncorhynchus mykiss (rainbow trout) Citation Extract: Yoshizaki G, Takashiba K, Shimamori S, Fujinuma K, Shikina S, Okutsu T, Kume S, Hayashi M. Production of germ cell-deficient salmonids by dead end gene knockdown, and their use as recipients for germ cell transplantation. Mol Reprod Dev. 2016 Feb 9. doi: 10.1002/mrd.22625. [Epub ahead of print]. |
DNA duplex-quadruplex exchange as the basis for a nanomolecular machine
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Citation:
Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1569-73. Epub 2003 Feb 6 Epub:
Not Epub Abstract:
There is currently great interest in the design of nanodevices that are capable of performing linear or rotary movements.... Citation Extract: Alberti P, Mergny JL. DNA duplex-quadruplex exchange as the basis for a nanomolecular machine. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1569-73. Epub 2003 Feb 6. |
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo
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Citation:
Mol Neurodegener. 2016;11:18. doi:10.1186/s13024-016-0076-5 Epub:
Not Epub Abstract:
Background: Prions and amyloid-β (Aβ) oligomers trigger neurodegeneration by hijacking a poorly understood cellular signal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sempou E, Biasini E, Pinzón-Olejua A, Harris DA, Málaga-Trillo E. Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo. Mol Neurodegener. 2016;11:18. doi:10.1186/s13024-016-0076-5. |
FOXE3 mutations predispose to thoracic aortic aneurysms and dissections
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Citation:
J Clin Invest. 2016 Feb 8. pii: 83778. doi: 10.1172/JCI83778. [Epub ahead of print] Epub:
Yes Abstract:
The ascending thoracic aorta is designed to withstand biomechanical forces from pulsatile blood. Thoracic aortic aneurysms and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuang SQ, Medina-Martinez O, Guo DC, Gong L, Regalado ES, Reynolds CL, Boileau C, Jondeau G, Prakash SK, Kwartler CS, Zhu LY, Peters AM, Duan XY, Bamshad MJ, Shendure J, Nickerson DA, Santos-Cortez RL, Dong X, Leal SM, Majesky MW, Swindell EC, Jamrich M, Milewicz DM. FOXE3 mutations predispose to thoracic aortic aneurysms and dissections. J Clin Invest. 2016 Feb 8. pii: 83778. doi: 10.1172/JCI83778. [Epub ahead of print]. |
Reducing synuclein accumulation improves neuronal survival after spinal cord injury
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Citation:
Exp Neurol. 2016 Feb 5. pii: S0014-4886(16)30026-7. doi: 10.1016/j.expneurol.2016.02.004. [Epub ahead of print] Epub:
Yes Abstract:
Spinal cord injury causes neuronal death, limiting subsequent regeneration and recovery. Thus, there is a need to develop... Organism or Cell Type:
lamprey Citation Extract: Fogerson SM, van Brummen AJ, Busch DJ, Allen SR, Roychaudhuri R, Banks SM, Klärner FG, Schrader T, Bitan G, Morgan JR. Reducing synuclein accumulation improves neuronal survival after spinal cord injury. Exp Neurol. 2016 Feb 5. pii: S0014-4886(16)30026-7. doi: 10.1016/j.expneurol.2016.02.004. [Epub ahead of print]. |
Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders
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Citation:
Toxicol Appl Pharmacol. 2016 Feb 4. pii: S0041-008X(16)30024-2. doi: 10.1016/j.taap.2016.02.001. [Epub ahead of print] Epub:
Yes Abstract:
Cytochrome P450 (CYP) enzymes for which there is no functional information are considered "orphan" CYPs. Previous... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lemaire B, Kubota A, O'Meara CM, Lamb DC, Tanguay RL, Goldstone JV, Stegeman JJ. Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders. Toxicol Appl Pharmacol. 2016 Feb 4. pii: S0041-008X(16)30024-2. doi: 10.1016/j.taap.2016.02.001. [Epub ahead of print]. |
L1.2, the zebrafish paralog of L1.1 and ortholog of the mammalian cell adhesion molecule L1 contributes to spinal cord regeneration in adult zebrafish
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Citation:
Restor Neurol Neurosci. 2016;[Epub ahead pf print] doi:10.3233/RNN-150602 Epub:
Yes Abstract:
Purpose:The aim of the study was to investigate the functional role of L1.2, the zebrafish paralog of L1.1 and ortholog of... Organism or Cell Type:
zebrafish Citation Extract: Chen T, Yu Y, Hu C, Schachner M. L1.2, the zebrafish paralog of L1.1 and ortholog of the mammalian cell adhesion molecule L1 contributes to spinal cord regeneration in adult zebrafish. Restor Neurol Neurosci. 2016;[Epub ahead pf print] doi:10.3233/RNN-150602. |
Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes
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Citation:
Sci Rep. 2016;6:20408. doi:10.1038/srep20408 Epub:
Not Epub Abstract:
The SUN (Sad-1/UNC-84) and KASH (Klarsicht/ANC-1/Syne/homology) proteins constitute the linker of nucleoskeleton and... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Luo Y, Lee I-W, Jo Y-J, Namgoong S, Kim N-H. Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes. Sci Rep. 2016;6:20408. doi:10.1038/srep20408. |
Zebrafish as a Model to Investigate Dynamin 2-Related Diseases
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Citation:
Sci Rep. 2016;6:20466. doi:10.1038/srep20466 Epub:
Not Epub Abstract:
Mutations in the dynamin-2 gene (DNM2) cause autosomal dominant centronuclear myopathy (CNM) and dominant intermediate Charcot-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bragato B, Gaudenzi G, Blasevich F, Pavesi G, Maggi L, Giunta M, Cotelli F, Mora M. Zebrafish as a Model to Investigate Dynamin 2-Related Diseases. Sci Rep. 2016;6:20466. doi:10.1038/srep20466. |