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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation

Authors:
Zheng W, Shen F, Hu R, Roy B, Yang J, Wang Q, Zhang F, King JC, Sergi C, Liu SM, Cordat E, Tang J, Cao Y, Ali D, Chen XZ
Citation:
J Am Soc Nephrol. 2016 Feb 2. pii: ASN.2015070836. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Autosomal dominant polycystic kidney disease pathogenesis can be recapitulated in animal models by gene mutations in or dosage...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng W, Shen F, Hu R, Roy B, Yang J, Wang Q, Zhang F, King JC, Sergi C, Liu SM, Cordat E, Tang J, Cao Y, Ali D, Chen XZ. Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation. J Am Soc Nephrol. 2016 Feb 2. pii: ASN.2015070836. [Epub ahead of print].

Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin

Authors:
Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C
Citation:
Nat Comm. 2016;7:10354. doi:10.1038/ncomms10354
Epub:
Not Epub
Abstract:
Development of the cerebral cortex requires regulation of proliferation and differentiation of neural stem cells and a diverse...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C. Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin. Nat Comm. 2016;7:10354. doi:10.1038/ncomms10354.

Detection of Klebsiella pneumoniae Infection with an Antisense Oligomer Against its Ribosomal RNA

Authors:
Chen L, Cheng D, Liu G, Dou S, Wang Y, Liu X, Liu Y, Rusckowski M
Citation:
Mol Imaging Biol. 2016 Feb 1. [Epub ahead of print]
Epub:
Yes
Abstract:
PURPOSE: Previously, we demonstrated specific accumulation into bacteria of a 12-mer phosphorodiamidate morpholino (MORF)...
Organism or Cell Type:
mice
Citation Extract:
Chen L, Cheng D, Liu G, Dou S, Wang Y, Liu X, Liu Y, Rusckowski M. Detection of Klebsiella pneumoniae Infection with an Antisense Oligomer Against its Ribosomal RNA. Mol Imaging Biol. 2016 Feb 1. [Epub ahead of print].

Two macrophage migration inhibitory factors regulate starfish larval immune cell chemotaxis

Authors:
Furukawa R, Tamaki K, Kaneko H
Citation:
Immunol Cell Biol. 2016 Apr;94(4):315-21. doi: 10.1038/icb.2016.6. Epub 2016 Feb 2.
Epub:
Yes
Abstract:
Immune cell recruitment is critical step in the inflammatory response and associated diseases. However, the underlying...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria pectinifera (sea star)
Citation Extract:
Furukawa R, Tamaki K, Kaneko H. Two macrophage migration inhibitory factors regulate starfish larval immune cell chemotaxis. Immunol Cell Biol. 2016 Apr;94(4):315-21. doi: 10.1038/icb.2016.6. Epub 2016 Feb 2..

Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration

Authors:
Govindan J, Tun KM, Iovine MK
Citation:
PLoS One. 2016 Feb 1;11(2):e0148202. doi: 10.1371/journal.pone.0148202. eCollection 2016
Epub:
Not Epub
Abstract:
Skeletal development is a tightly regulated process and requires proper communication between the cells for efficient exchange...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Govindan J, Tun KM, Iovine MK. Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration. PLoS One. 2016 Feb 1;11(2):e0148202. doi: 10.1371/journal.pone.0148202. eCollection 2016.

Formin-2 regulates stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo

Authors:
Sahasrabudhe A, Ghate K, Mutalik S, Jacob A, Ghose A
Citation:
Development. 2016. 143:449-60. doi:10.1242/dev.130104
Epub:
Not Epub
Abstract:
Growth cone filopodia are actin-based mechanosensory structures that are essential for chemoreception and the generation of...
Delivery Method:
electroporation
Citation Extract:
Sahasrabudhe A, Ghate K, Mutalik S, Jacob A, Ghose A. Formin-2 regulates stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo. Development. 2016. 143:449-60. doi:10.1242/dev.130104.

The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling

Authors:
Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW
Citation:
Genes Dev. 2002 Apr 1;16(7):820-35
Epub:
Not Epub
Abstract:
We investigated the regulation of the activin/nodal-inducible distal element (DE) of the Xenopus goosecoid (gsc) promoter. On...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW. The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling. Genes Dev. 2002 Apr 1;16(7):820-35.

Histone deacetylase 1 is required for the development of the zebrafish inner ear

Authors:
He Y, Tang D, Li W, Chai R, Li H
Citation:
Sci Rep. 2016;6:16535. doi:10.1038/srep16535
Epub:
Not Epub
Abstract:
Histone deacetylase 1 (HDAC1) has been reported to be important for multiple aspects of normal embryonic development, but...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He Y, Tang D, Li W, Chai R, Li H. Histone deacetylase 1 is required for the development of the zebrafish inner ear. Sci Rep. 2016;6:16535. doi:10.1038/srep16535.

MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis

Authors:
Wang X, Ling CC, Li L, Qin Y, Qi J, Liu X, You B, Shi Y, Zhang J, Jiang Q, Xu H, Sun C, You Y, Chai R, Liu D
Citation:
Cardiovasc Res. 2016 Jan 29. pii: cvw023. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNA-10 (miR-10) was originally shown to regulate angiogenesis by directly modulating the levels of membrane-bound fms-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Ling CC, Li L, Qin Y, Qi J, Liu X, You B, Shi Y, Zhang J, Jiang Q, Xu H, Sun C, You Y, Chai R, Liu D. MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovasc Res. 2016 Jan 29. pii: cvw023. [Epub ahead of print].

The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells

Authors:
Rodrigues-Diez RR, Garcia-Redondo AB, Orejudo M, Rodrigues-Diez R, Briones AM, Bosch-Panadero E, Kery G, Pato J, Ortiz A, Salaices M, Egido J, Ruiz-Ortega M
Citation:
Antioxid Redox Signal. 2015 Jan 1;22(1):29-47. doi: 10.1089/ars.2013.5500
Epub:
Not Epub
Abstract:
AIMS: Connective tissue growth factor (CTGF/CCN2) is a developmental gene upregulated in pathological conditions, including...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Rodrigues-Diez RR, Garcia-Redondo AB, Orejudo M, Rodrigues-Diez R, Briones AM, Bosch-Panadero E, Kery G, Pato J, Ortiz A, Salaices M, Egido J, Ruiz-Ortega M. The C-terminal module IV of connective tissue growth factor, through EGFR/Nox1 signaling, activates the NF-κB pathway and proinflammatory factors in vascular smooth muscle cells. Antioxid Redox Signal. 2015 Jan 1;22(1):29-47. doi: 10.1089/ars.2013.5500.

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