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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly

Authors:
Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ
Citation:
Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print]
Epub:
Yes
Abstract:
Adprhl1, a member of the ADP-ribosylhydrolase protein family, is expressed exclusively in the developing heart of all...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ. The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly. Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print].

Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)

Authors:
Brown DR, Clark BW, Garner LV, Di Giulio RT
Citation:
Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
High affinity aryl hydrocarbon receptor (AHR) ligands, such as certain polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo...
Delivery Method:
microinjection
Organism or Cell Type:
Fundulus heteroclitus (killifish)
Citation Extract:
Brown DR, Clark BW, Garner LV, Di Giulio RT. Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus). Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print].

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Authors:
Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F
Citation:
Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5
Epub:
Not Epub
Abstract:
The differentiation of HSCs into myeloid lineages requires the transcription factor PU.1. Whereas PU.1-dependent induction of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F. Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5.

Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing

Authors:
Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C
Citation:
Dev Biol. 2016 May 18. pii: S0012-1606(16)30125-7. doi: 10.1016/j.ydbio.2016.05.014. [Epub ahead of print]
Epub:
Yes
Abstract:
During early vertebrate embryogenesis, cell fate specification is often coupled with cell acquisition of specific adhesive,...
Organism or Cell Type:
Xenopus
Citation Extract:
Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C. Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing. Dev Biol. 2016 May 18. pii: S0012-1606(16)30125-7. doi: 10.1016/j.ydbio.2016.05.014. [Epub ahead of print].

Calmodulin Mediates Ca2+-Dependent Inhibition of Tie2 Signaling and Acts as a Developmental Brake During Embryonic Angiogenesis

Authors:
Yang C, Ohk J, Lee JY, Kim EJ, Kim J, Han S, Park D, Jung H, Kim C
Citation:
Arterioscler Thromb Vasc Biol. 2016 May 19. pii: ATVBAHA.116.307619. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Angiogenesis, the process of building complex vascular structures, begins with sprout formation on preexisting blood...
Organism or Cell Type:
Xenopus
Citation Extract:
Yang C, Ohk J, Lee JY, Kim EJ, Kim J, Han S, Park D, Jung H, Kim C. Calmodulin Mediates Ca2+-Dependent Inhibition of Tie2 Signaling and Acts as a Developmental Brake During Embryonic Angiogenesis. Arterioscler Thromb Vasc Biol. 2016 May 19. pii: ATVBAHA.116.307619. [Epub ahead of print].

Cyp2aa9 regulates haematopoietic stem cell development in zebrafish

Authors:
Chen J, He J, Li L, Yang D, Luo L
Citation:
Sci Rep. 2016;6:26608. doi:10.1038/srep26608
Epub:
Not Epub
Abstract:
Definitive haematopoiesis occurs during the lifetime of an individual, which continuously replenishes all blood and immune...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, He J, Li L, Yang D, Luo L. Cyp2aa9 regulates haematopoietic stem cell development in zebrafish. Sci Rep. 2016;6:26608. doi:10.1038/srep26608.

Cardiac troponin T is necessary for normal development in the embryonic chick heart

Authors:
England J, Pang KL, Parnall M, Haig MI, Loughna S
Citation:
J Anat. 2016 May 19. doi: 10.1111/joa.12486. [Epub ahead of print]
Epub:
Yes
Abstract:
The heart is the first functioning organ to develop during embryogenesis. The formation of the heart is a tightly regulated and...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
England J, Pang KL, Parnall M, Haig MI, Loughna S. Cardiac troponin T is necessary for normal development in the embryonic chick heart. J Anat. 2016 May 19. doi: 10.1111/joa.12486. [Epub ahead of print].

Elongator Protein 3 (Elp3) stabilizes Snail1 and regulates neural crest migration in Xenopus

Authors:
Yang X, Li J, Zeng W, Li C, Mao B
Citation:
Sci Rep. 2016 May 18;6:26238. doi: 10.1038/srep26238
Epub:
Not Epub
Abstract:
Elongator protein 3 (Elp3) is the enzymatic unit of the elongator protein complex, a histone acetyltransferase complex involved...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yang X, Li J, Zeng W, Li C, Mao B. Elongator Protein 3 (Elp3) stabilizes Snail1 and regulates neural crest migration in Xenopus. Sci Rep. 2016 May 18;6:26238. doi: 10.1038/srep26238.

The defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish

Authors:
Chen D, Li F, Yang Q, Tian M, Zhang Z, Zhang Q, Chen Y, Guan MX
Citation:
Int J Biochem Cell Biol. 2016 May 13. pii: S1357-2725(16)30118-2. doi: 10.1016/j.biocel.2016.05.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Human mitochondrial DNA (mtDNA) mutations have been associated with a wide spectrum of clinical abnormalities. However, nuclear...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen D, Li F, Yang Q, Tian M, Zhang Z, Zhang Q, Chen Y, Guan MX. The defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish. Int J Biochem Cell Biol. 2016 May 13. pii: S1357-2725(16)30118-2. doi: 10.1016/j.biocel.2016.05.012. [Epub ahead of print].

Reiterative expression of pax1 directs pharyngeal pouch segmentation in medaka

Authors:
Okada K, Inohaya K, Mise T, Kudo A, Takada S, Wada H
Citation:
Development. 2016 May 15;143(10):1800-1810. Epub 2016 Mar 31
Epub:
Not Epub
Abstract:
A striking characteristic of vertebrate development is the pharyngeal arches, which are a series of bulges on the lateral...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Okada K, Inohaya K, Mise T, Kudo A, Takada S, Wada H. Reiterative expression of pax1 directs pharyngeal pouch segmentation in medaka. Development. 2016 May 15;143(10):1800-1810. Epub 2016 Mar 31.

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