You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
A novel developmental role for dopaminergic signaling to specify hypothalamic neurotransmitter identity
|
Citation:
J Biol Chem. 2016 Aug 18. pii: jbc.M115.697466. [Epub ahead of print] Epub:
Yes Abstract:
Hypothalamic neurons expressing histamine and orexin/ hypocretin (hcrt) are necessary for normal regulation of wakefulness. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen YC, Semenova S, Rozov S, Sundvik M, Bonkowsky JL, Panula P. A novel developmental role for dopaminergic signaling to specify hypothalamic neurotransmitter identity. J Biol Chem. 2016 Aug 18. pii: jbc.M115.697466. [Epub ahead of print]. |
Quantitative Microinjection of Morpholino Antisense Oligonucleotides into Mouse Oocytes to Examine Gene Function in Meiosis-I
|
Citation:
Methods Mol Biol. 2016;1457:217-30. doi: 10.1007/978-1-4939-3795-0_16 Epub:
Not Epub Abstract:
Specific protein depletion is a powerful approach for assessing individual gene function in cellular processes, and has been... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Nakagawa S, FitzHarris G. Quantitative Microinjection of Morpholino Antisense Oligonucleotides into Mouse Oocytes to Examine Gene Function in Meiosis-I. Methods Mol Biol. 2016;1457:217-30. doi: 10.1007/978-1-4939-3795-0_16. |
Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates
|
Citation:
J Neuromuscul Dis. 2016 Aug 30;3(3):381-393. Epub:
Not Epub Abstract:
Background: Phosphorodiamidate morpholino oligomers (PMOs) are a class of exon skipping drugs including eteplirsen, which has... Delivery Method:
i.v. injection Organism or Cell Type:
nonhuman primates Citation Extract: Carver MP, Charleston JS, Shanks C, Zhang JB, Mense M, Sharma A, Kaur H, Sazani P. Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates. J Neuromuscul Dis. 2016 Aug 30;3(3):381-393.. |
Physical association between a novel plasma-membrane structure and centrosome orients cell division
|
Citation:
Elife. 2016 Aug 9;5. pii: e16550. doi: 10.7554/eLife.16550 Epub:
Not Epub Abstract:
In the last mitotic division of the epidermal lineage in the ascidian embryo, the cells divide stereotypically along the... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Negishi T, Miyazaki N, Murata K, Yasuo H, Ueno N. Physical association between a novel plasma-membrane structure and centrosome orients cell division. Elife. 2016 Aug 9;5. pii: e16550. doi: 10.7554/eLife.16550. |
HDAC1 negatively regulates Bdnf and Pvalb required for parvalbumin interneuron maturation in an experience-dependent manner
|
Citation:
J Neurochem. 2016 Aug 17. doi: 10.1111/jnc.13773. [Epub ahead of print] Epub:
Yes Abstract:
During early postnatal development, neuronal circuits are sculpted by sensory experience provided by the external environment.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Koh DX, Sng JC. HDAC1 negatively regulates Bdnf and Pvalb required for parvalbumin interneuron maturation in an experience-dependent manner. J Neurochem. 2016 Aug 17. doi: 10.1111/jnc.13773. [Epub ahead of print]. |
Singapore grouper iridovirus protein VP088 is essential for viral infectivity
|
Citation:
Sci Rep. 2016 Aug 8;6:31170. doi: 10.1038/srep31170 Epub:
Not Epub Abstract:
Viral infection is a great challenge in healthcare and agriculture. The Singapore grouper iridovirus (SGIV) is highly... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: Oryzias latipes (Medaka) haploid ES cell line HX1 Citation Extract: Yuan Y, Wang Y, Liu Q, Zhu F, Hong Y. Singapore grouper iridovirus protein VP088 is essential for viral infectivity. Sci Rep. 2016 Aug 8;6:31170. doi: 10.1038/srep31170. |
Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo
|
Citation:
Cell Host Microbe. 2016 Aug 10;20(2):250-8. doi: 10.1016/j.chom.2016.07.007 Epub:
Not Epub Abstract:
The blockade of phagolysosomal fusion is considered a critical mycobacterial strategy to survive in macrophages. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Levitte S, Adams KN, Berg RD, Cosma CL, Urdahl KB, Ramakrishnan L. Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo. Cell Host Microbe. 2016 Aug 10;20(2):250-8. doi: 10.1016/j.chom.2016.07.007. |
Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis
|
Citation:
Proc Natl Acad Sci U S A. 2016 Aug 9. pii: 201523116. [Epub ahead of print] Epub:
Yes Abstract:
Innate cellular immune responses are a critical first-line defense against invading bacterial pathogens. Leukocyte migration... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bhuiyan MS, Ellett F, Murray GL, Kostoulias X, Cerqueira GM, Schulze KE, Mahamad Maifiah MH, Li J, Creek DJ, Lieschke GJ, Peleg AY. Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis. Proc Natl Acad Sci U S A. 2016 Aug 9. pii: 201523116. [Epub ahead of print]. |
Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome
|
Citation:
Am J Hum Genet. 2016 Aug 4;99(2):318-36. doi: 10.1016/j.ajhg.2015.04.023 Epub:
Not Epub Abstract:
Bardet-Biedl syndrome (BBS) is a defining ciliopathy, notable for extensive allelic and genetic heterogeneity, almost all of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lindstrand A, Frangakis S, Carvalho CM, Richardson EB, McFadden KA, Willer JR, Pehlivan D, Liu P, Pediaditakis IL, Sabo A, Lewis RA, Banin E, Lupski JR, Davis EE, Katsanis N. Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome. Am J Hum Genet. 2016 Aug 4;99(2):318-36. doi: 10.1016/j.ajhg.2015.04.023. |
The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype
|
Citation:
Am J Hum Genet. 2016 Aug 3. pii: S0002-9297(16)30288-9. doi: 10.1016/j.ajhg.2016.07.014. [Epub ahead of print] Epub:
Yes Abstract:
Homozygous loss of SMN1 causes spinal muscular atrophy (SMA), the most common and devastating childhood genetic motor-neuron... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hosseinibarkooie S, Peters M, Torres-Benito L, Rastetter RH, Hupperich K, Hoffmann A, Mendoza-Ferreira N, Kaczmarek A, Janzen E, Milbradt J, Lamkemeyer T, Rigo F, Bennett CF, Guschlbauer C, Büschges A, Hammerschmidt M, Riessland M, Kye MJ, Clemen CS, Wirth B. The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype. Am J Hum Genet. 2016 Aug 3. pii: S0002-9297(16)30288-9. doi: 10.1016/j.ajhg.2016.07.014. [Epub ahead of print]. |