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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Antisense targeting of 3'end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for Facioscapulohumeral Dystrophy: a new gene silencing approach
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Citation:
Hum Mol Genet. 2016 Jan 19. pii: ddw015. [Epub ahead of print] Epub:
Yes Abstract:
Defects in mRNA 3' end formation have been described to alter transcription termination, transport of the mRNA from the... Delivery Method:
DNA leash and lipofectamine Organism or Cell Type:
cell culture: differentiated immortalized FSHD myotubes Citation Extract: Marsollier AC, Ciszewski L, Mariot V, Popplewell L, Voit T, Dickson G, Dumonceaux J. Antisense targeting of 3'end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for Facioscapulohumeral Dystrophy: a new gene silencing approach. Hum Mol Genet. 2016 Jan 19. pii: ddw015. [Epub ahead of print]. |
Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action
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Citation:
Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30020-X. doi: 10.1016/j.mce.2016.01.020. [Epub ahead of print] Epub:
Yes Abstract:
Resistance to thyroid hormone can be due to heterozygous, dominant negative (DN) THRA (RTHα) or THRB (RTHβ) mutations, but the... Organism or Cell Type:
zebrafish Citation Extract: Marelli F, Carra S, Agostini M, Cotelli F, Peeters R, Chatterjee K, Persani L. Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action. Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30020-X. doi: 10.1016/j.mce.2016.01.020. [Epub ahead of print]. |
Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function
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Citation:
Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30018-1. doi: 10.1016/j.mce.2016.01.018. [Epub ahead of print] Epub:
Yes Abstract:
Retinal development in vertebrates relies extensively on thyroid hormones. Their local availability is tightly controlled by... Organism or Cell Type:
zebrafish Citation Extract: Houbrechts AM, Vergauwen L, Bagci E, Van Houcke J, Heijlen M, Kulemeka B, Hyde DR, Knapen D, Darras VM. Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function. Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30018-1. doi: 10.1016/j.mce.2016.01.018. [Epub ahead of print]. |
GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway
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Citation:
Cell Death Dis. 2016 Jan 21;7:e2068. doi: 10.1038/cddis.2015.300 Epub:
Not Epub Abstract:
GADD45 gene has been implicated in cell cycle arrest, cell survival or apoptosis in a cell type specific and context-dependent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen Z, Wan X, Hou Q, Shi S, Wang L, Chen P, Zhu X, Zeng C, Qin W, Zhou W, Liu Z. GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway. Cell Death Dis. 2016 Jan 21;7:e2068. doi: 10.1038/cddis.2015.300. |
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
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Citation:
Sci Signal. 2016;9(411):ra8. doi:10.1126/scisignal.aad0848 Epub:
Not Epub Abstract:
Because signaling mediated by the transcription factor nuclear factor κB (NF-κB) is initiated by ligands and receptors that can... Organism or Cell Type:
zebrafish Citation Extract: Mamińska A, Anna Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon T, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M. ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors. Sci Signal. 2016;9(411):ra8. doi:10.1126/scisignal.aad0848. |
Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells
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Citation:
BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x Epub:
Not Epub Abstract:
Background: The three members of the human heterochromatin protein 1 (HP1) family of proteins, HP1α, HP1β, and HPγ, are... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: MDA-MB-231 Citation Extract: Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL. Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells. BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x. |
Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling
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Citation:
Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print] Epub:
Not Epub Abstract:
EFHC1 encodes a ciliary protein that has been linked to Juvenile Myoclonic Epilepsy. In ectodermal explants, derived from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Zhao Y, Shi J, Winey M, Klymkowsky MW. Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling. Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print]. |
Microtubule-associated protein 1b is required for shaping the neural tube
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Citation:
Neural Dev. 2016 Jan 18;11(1):1. doi: 10.1186/s13064-015-0056-4 Epub:
Not Epub Abstract:
BACKGROUND: Shaping of the neural tube, the precursor of the brain and spinal cord, involves narrowing and elongation of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jayachandran P, Olmo VN, Sanchez SP, McFarland RJ, Vital E, Werner JM, Hong E, Sanchez-Alberola N, Molodstov A, Brewster RM. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016 Jan 18;11(1):1. doi: 10.1186/s13064-015-0056-4. |
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development
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Citation:
BMC Dev Biol. 2016;[Epub ahead of print] doi:10.1186/s12861-016-0101-5 Epub:
Not Epub Abstract:
Background: Bone morphogenetic proteins regulate multiple processes in embryonic development, including early dorso-ventral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schille C, Heller J, Schambony A. Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development. BMC Dev Biol. 2016;[Epub ahead of print] doi:10.1186/s12861-016-0101-5. |
Evolution of the fish heart by sub/neofunctionalization of an elastin gene
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Citation:
Nat Comm. 2016;7:10397. doi:10.1038/ncomms10397 Epub:
Not Epub Abstract:
The evolution of phenotypic traits is a key process in diversification of life. However, the mechanisms underlying the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moriyama Y, Ito F, Takeda H, Yano T, Okabe M, Kuraku S, Keeley FW, Koshiba-Takeuchi K. Evolution of the fish heart by sub/neofunctionalization of an elastin gene. Nat Comm. 2016;7:10397. doi:10.1038/ncomms10397. |