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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio)

Authors:
Lin CH, Hu HJ, Hwang PP
Citation:
Mol Cell Endocrinol. 2015 Dec 8. pii: S0303-7207(15)30156-8. doi: 10.1016/j.mce.2015.12.001. [Epub ahead of print]
Epub:
Yes
Abstract:
In mammals, sodium/hydrogen exchanger (NHE) and sodium-chloride cotransporter (NCC) are expressed in renal tubules, and exhibit...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CH, Hu HJ, Hwang PP. Cortisol regulates sodium homeostasis by stimulating the transcription of sodium-chloride transporter (NCC) in zebrafish (Danio rerio). Mol Cell Endocrinol. 2015 Dec 8. pii: S0303-7207(15)30156-8. doi: 10.1016/j.mce.2015.12.001. [Epub ahead of print].

Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development

Authors:
Metikala S, Neuhaus H, Hollemann T
Citation:
Angiogenesis. 2015 Dec 17. [Epub ahead of print] doi:10.​1007/​s10456-015-9492-3
Epub:
Yes
Abstract:
In the adult, new vessels and red blood cells form in response to hypoxia. Here, the oxygen-sensing system (PHD-HIF) has...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Metikala S, Neuhaus H, Hollemann T. Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development. Angiogenesis. 2015 Dec 17. [Epub ahead of print] doi:10.​1007/​s10456-015-9492-3.

The water channel aquaporin-1a1 facilitates movement of CO2 and ammonia in zebrafish (Danio rerio) larvae

Authors:
Talbot K, Kwong RW, Gilmour KM, Perry SF
Citation:
J Exp Biol. 2015 Dec;218(Pt 24):3931-40. doi: 10.1242/jeb.129759
Epub:
Not Epub
Abstract:
The present study tested the hypothesis that zebrafish (Danio rerio) aquaporin-1a1 (AQP1a1) serves as a multi-functional...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Talbot K, Kwong RW, Gilmour KM, Perry SF. The water channel aquaporin-1a1 facilitates movement of CO2 and ammonia in zebrafish (Danio rerio) larvae. J Exp Biol. 2015 Dec;218(Pt 24):3931-40. doi: 10.1242/jeb.129759.

Metabolic regulation of the ultradian oscillator Hes1 by reactive oxygen species

Authors:
Ventre S, Indrieri A, Fracassi C, Franco B, Conte I, Cardone L, di Bernardo D
Citation:
J Mol Biol. 2015 May 22;427(10):1887-902. doi: 10.1016/j.jmb.2015.03.007. Epub 2015 Mar 18
Epub:
Not Epub
Abstract:
Ultradian oscillators are cyclically expressed genes with a period of less than 24h, found in the major signalling pathways....
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Ventre S, Indrieri A, Fracassi C, Franco B, Conte I, Cardone L, di Bernardo D. Metabolic regulation of the ultradian oscillator Hes1 by reactive oxygen species. J Mol Biol. 2015 May 22;427(10):1887-902. doi: 10.1016/j.jmb.2015.03.007. Epub 2015 Mar 18.

A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes

Authors:
Shahidi R, Williams EA, Conzelmann M, Asadulina A, Verasztó C, Jasek S, Bezares-Calderón LA, Jékely G
Citation:
Elife. 2015 Dec 15;4. pii: e11147. doi: 10.7554/eLife.11147. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Electron microscopy-based connectomics aims to comprehensively map synaptic connections in neural tissue. However, current...
Delivery Method:
microinjection
Organism or Cell Type:
Platynereis dumerilii
Citation Extract:
Shahidi R, Williams EA, Conzelmann M, Asadulina A, Verasztó C, Jasek S, Bezares-Calderón LA, Jékely G. A serial multiplex immunogold labeling method for identifying peptidergic neurons in connectomes. Elife. 2015 Dec 15;4. pii: e11147. doi: 10.7554/eLife.11147. [Epub ahead of print].

Progesterone receptor membrane component-1 regulates hepcidin biosynthesis

Authors:
Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT
Citation:
J Clin Invest. 2015 Dec 14. pii: 83831. doi: 10.1172/JCI83831. [Epub ahead of print]
Epub:
Yes
Abstract:
Iron homeostasis is tightly regulated by the membrane iron exporter ferroportin and its regulatory peptide hormone hepcidin....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT. Progesterone receptor membrane component-1 regulates hepcidin biosynthesis. J Clin Invest. 2015 Dec 14. pii: 83831. doi: 10.1172/JCI83831. [Epub ahead of print].

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo

Authors:
de Bruin A, Cornelissen PWA, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang K-H, Végh AMD, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ
Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv1471
Epub:
Yes
Abstract:
In this study, we explored the existence of a transcriptional network co-regulated by E2F7 and HIF1α, as we show that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Bruin A, Cornelissen PWA, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang K-H, Végh AMD, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ. Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv1471.

MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome

Authors:
Chiavacci E, D'Aurizio R, Guzzolino E, Russo F, Baumgart M, Groth M, Mariani L, D'Onofrio M, Arisi I, Pellegrini M, Cellerino A, Cremisi F, Pitto L
Citation:
Sci Rep. 2015 Dec 14;5:18240. doi: 10.1038/srep18240
Epub:
Not Epub
Abstract:
Holt-Oram Syndrome (HOS) is an autosomal dominant heart-hand syndrome caused by mutations in the TBX5 gene, a transcription...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiavacci E, D'Aurizio R, Guzzolino E, Russo F, Baumgart M, Groth M, Mariani L, D'Onofrio M, Arisi I, Pellegrini M, Cellerino A, Cremisi F, Pitto L. MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome. Sci Rep. 2015 Dec 14;5:18240. doi: 10.1038/srep18240.

Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis

Authors:
Overton JD, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, Fedeles SV, Habas R, Runnels LW
Citation:
Sci Rep. 2015 Dec 16;5:18395. doi: 10.1038/srep18395
Epub:
Not Epub
Abstract:
Mutations in protein kinase C substrate 80K-H (PRKCSH), which encodes for an 80 KDa protein named hepatocystin (80K-H, PRKCSH...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Overton JD, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, Fedeles SV, Habas R, Runnels LW. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Sci Rep. 2015 Dec 16;5:18395. doi: 10.1038/srep18395.

Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos

Authors:
Li J, Yue Y, Zhao Q
Citation:
Zebrafish. 2015 Dec 15. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid (RA) plays important roles in many stages of heart morphogenesis. Zebrafish embryos treated with exogenous RA...
Organism or Cell Type:
zebrafish
Citation Extract:
Li J, Yue Y, Zhao Q. Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos. Zebrafish. 2015 Dec 15. [Epub ahead of print].

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