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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection

Authors:
Ningappa M, Ashokkumar C, Higgs BW, Sun Q, Jaffe R, Mazariegos G, Li D, Weeks DE, Subramaniam S, Ferrell R, Hakonarson H, Sindhi R
Citation:
Am J Transplant. 2015 Dec 11. doi: 10.1111/ajt.13509. [Epub ahead of print]
Epub:
Yes
Abstract:
T cell suppression prevents acute cellular rejection but causes life-threatening infections and malignancies. Previously, liver...
Organism or Cell Type:
cell culture: lymphoblastoid B cells (Raji cells)
Citation Extract:
Ningappa M, Ashokkumar C, Higgs BW, Sun Q, Jaffe R, Mazariegos G, Li D, Weeks DE, Subramaniam S, Ferrell R, Hakonarson H, Sindhi R. Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection. Am J Transplant. 2015 Dec 11. doi: 10.1111/ajt.13509. [Epub ahead of print].

Pou5f3.2-induced proliferative state of embryonic cells during gastrulation of Xenopus laevis embryo

Authors:
Nishitani E, Li C, Lee J, Hotta H, Katayama Y, Yamaguchi M, Kinoshita T
Citation:
Dev Growth Differ. 2015 Dec 14. doi: 10.1111/dgd.12246. [Epub ahead of print]
Epub:
Yes
Abstract:
POU class V (POU-V) transcription factors play the important role in maintenance of pluripotency and cell differentiation....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nishitani E, Li C, Lee J, Hotta H, Katayama Y, Yamaguchi M, Kinoshita T. Pou5f3.2-induced proliferative state of embryonic cells during gastrulation of Xenopus laevis embryo. Dev Growth Differ. 2015 Dec 14. doi: 10.1111/dgd.12246. [Epub ahead of print].

Neurogenic gene regulatory pathways in the sea urchin embryo

Authors:
Wei Z, Angerer LM, Angerer RC
Citation:
Development. 2015 Dec 10. pii: dev.125989. [Epub ahead of print]
Epub:
Yes
Abstract:
During embryogenesis the sea urchin early pluteus larva differentiates 40-50 neurons marked by expression of the pan-neural...
Organism or Cell Type:
sea urchin
Citation Extract:
Wei Z, Angerer LM, Angerer RC. Neurogenic gene regulatory pathways in the sea urchin embryo. Development. 2015 Dec 10. pii: dev.125989. [Epub ahead of print].

Tumor Suppressor Lzap Suppresses Wnt/β-catenin signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of GSK3

Authors:
Lin KY, Kao SH, Lai CM, Chen CT, Wu CY, Hsu HJ, Wang WD
Citation:
J Biol Chem. 2015 Oct 16. pii: jbc.M115.669309. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling controls various cell fates in metazoan development, and its dysregulation is often associated with...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin KY, Kao SH, Lai CM, Chen CT, Wu CY, Hsu HJ, Wang WD. Tumor Suppressor Lzap Suppresses Wnt/β-catenin signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of GSK3. J Biol Chem. 2015 Oct 16. pii: jbc.M115.669309. [Epub ahead of print].

Morpholino antisense oligo inhibits trans-splicing of pre-inositol 1,4,5-trisphosphate receptor mRNA of Trypanosoma cruzi and suppresses parasite growth and infectivity

Authors:
Hashimoto M, Nara T, Mita T, Mikoshiba K
Citation:
Parasit Internat. 2015;[Epub ahead of print] doi:10.1016/j.parint.2015.12.001
Epub:
Yes
Abstract:
Morpholino antisense oligos (MAOs) are used to investigate physiological gene function by inhibiting gene translation or...
Organism or Cell Type:
Trypanosoma cruzi
Citation Extract:
Hashimoto M, Nara T, Mita T, Mikoshiba K. Morpholino antisense oligo inhibits trans-splicing of pre-inositol 1,4,5-trisphosphate receptor mRNA of Trypanosoma cruzi and suppresses parasite growth and infectivity. Parasit Internat. 2015;[Epub ahead of print] doi:10.1016/j.parint.2015.12.001.

Cartilage development requires the function of Estrogen-related receptor alpha that directly regulates sox9 expression in zebrafish

Authors:
Kim Y-I, Lee JN, Bhandari S, Nam I-K, Yoo K-W, Kim S-J, Oh G-S, Kim H-J, So H-S, Choe S-K,Park R
Citation:
Sci Reb. 2015;5:18011. doi:10.1038/srep18011
Epub:
Not Epub
Abstract:
Estrogen-related receptor alpha (ESRRa) regulates a number of cellular processes including development of bone and muscles....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim Y-I, Lee JN, Bhandari S, Nam I-K, Yoo K-W, Kim S-J, Oh G-S, Kim H-J, So H-S, Choe S-K,Park R. Cartilage development requires the function of Estrogen-related receptor alpha that directly regulates sox9 expression in zebrafish. Sci Reb. 2015;5:18011. doi:10.1038/srep18011.

Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure

Authors:
McMillin M, Frampton G, Quinn M, Ashfaq S, de los Santos III M, Grant S, DeMorrow S
Citation:
Am J Pathol. 2015;186(2):312–23. doi:10.1016/j.ajpath.2015.10.005
Epub:
Yes
Abstract:
Hepatic encephalopathy is a serious neurological complication of liver failure. Serum bile acids are elevated after liver...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
McMillin M, Frampton G, Quinn M, Ashfaq S, de los Santos III M, Grant S, DeMorrow S. Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure. Am J Pathol. 2015;186(2):312–23. doi:10.1016/j.ajpath.2015.10.005.

Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish

Authors:
Griffin A, Parajes S, Weger M, Zaucker A, Taylor AE, O'Neil DM, Müller F, Krone N
Citation:
Endocrinology. 2015 Dec 9:en20151480. [Epub ahead of print]
Epub:
Yes
Abstract:
Mitochondrial cytochrome P450 (CYP) enzymes rely on electron transfer from the redox partner ferredoxin (FDX1) for catalytic...
Organism or Cell Type:
zebrafish
Citation Extract:
Griffin A, Parajes S, Weger M, Zaucker A, Taylor AE, O'Neil DM, Müller F, Krone N. Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish. Endocrinology. 2015 Dec 9:en20151480. [Epub ahead of print].

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

Authors:
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LCF, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK
Citation:
Cell Host & Microbe. 2015;18(6):723-35. doi:10.1016/j.chom.2015.11.002
Epub:
Not Epub
Abstract:
Several systems-level datasets designed to dissect host-pathogen interactions during influenza A infection have been reported....
Delivery Method:
peptide-linked
Organism or Cell Type:
BALB/c mice
Citation Extract:
Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LCF, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK. Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding. Cell Host & Microbe. 2015;18(6):723-35. doi:10.1016/j.chom.2015.11.002.

Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos

Authors:
Lee H-C, Lo H-C, Lo D-M, Su M-Y, Hu J-R, Wu C-C, Chang S-N, Dai M-S, Tsai C-T, Tsai H-J
Citation:
PLoS ONE. 2015;10(12):e0144751. doi:10.1371/journal.pone.0144751
Epub:
Not Epub
Abstract:
Although Amiodarone, a class III antiarrhythmic drug, inhibits zebrafish cardiac valve formation, the detailed molecular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee H-C, Lo H-C, Lo D-M, Su M-Y, Hu J-R, Wu C-C, Chang S-N, Dai M-S, Tsai C-T, Tsai H-J. Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos. PLoS ONE. 2015;10(12):e0144751. doi:10.1371/journal.pone.0144751.

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