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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy

Authors:
Li M, Andersson-Lendahl M, Sejersen T, Arner A
Citation:
J Gen Physiol. 2016;147:309-322. doi:10.1085/jgp.201511452
Epub:
Not Epub
Abstract:
Myosin-binding protein C (MyBPC) in the muscle sarcomere interacts with several contractile and structural proteins. Mutations...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li M, Andersson-Lendahl M, Sejersen T, Arner A. Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy. J Gen Physiol. 2016;147:309-322. doi:10.1085/jgp.201511452.

Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration

Authors:
Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L
Citation:
Cell. 2016 Mar 24;165(1):139-52. doi: 10.1016/j.cell.2016.02.034
Epub:
Not Epub
Abstract:
A zebrafish genetic screen for determinants of susceptibility to Mycobacterium marinum identified a hypersusceptible mutant...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L. Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. Cell. 2016 Mar 24;165(1):139-52. doi: 10.1016/j.cell.2016.02.034.

Cell-fate determination by ubiquitin-dependent regulation of translation

Authors:
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M
Citation:
Nature. 2015 Sep 24;525(7570):523-7. doi: 10.1038/nature14978
Epub:
Not Epub
Abstract:
Metazoan development depends on the accurate execution of differentiation programs that allow pluripotent stem cells to adopt...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015 Sep 24;525(7570):523-7. doi: 10.1038/nature14978.

Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition

Authors:
Zhang M, Kothari P, Mullins M, Lampson MA
Citation:
Cell Cycle. 2014;13(24):3828-38. doi: 10.4161/15384101.2014.967066
Epub:
Not Epub
Abstract:
Following fertilization, oviparous embryos undergo rapid, mostly transcriptionally silent cleavage divisions until the mid-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang M, Kothari P, Mullins M, Lampson MA. Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition. Cell Cycle. 2014;13(24):3828-38. doi: 10.4161/15384101.2014.967066.

Conditions that influence the response to Fgf during otic placode induction

Authors:
Padanad MS, Bhat N, Guo B, Riley BB
Citation:
Dev Biol. 2012 Apr 1;364(1):1-10. doi: 10.1016/j.ydbio.2012.01.022. Epub 2012 Feb 1
Epub:
Not Epub
Abstract:
Despite the vital importance of Fgf for otic induction, previous attempts to study otic induction through Fgf misexpression...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Padanad MS, Bhat N, Guo B, Riley BB. Conditions that influence the response to Fgf during otic placode induction. Dev Biol. 2012 Apr 1;364(1):1-10. doi: 10.1016/j.ydbio.2012.01.022. Epub 2012 Feb 1.

Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Authors:
Hong N, Li M, Yuan Y, Wang T, Yi M, Xu H, Zeng H, Song J, Hong Y
Citation:
Stem Cell Reports. 2016 Mar 8;6(3):411-21. doi: 10.1016/j.stemcr.2016.01.002. Epub 2016 Feb 4
Epub:
Not Epub
Abstract:
Primordial germ cell (PGC) specification occurs early in development. PGC specifiers have been identified in Drosophila, mouse...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Hong N, Li M, Yuan Y, Wang T, Yi M, Xu H, Zeng H, Song J, Hong Y. Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish. Stem Cell Reports. 2016 Mar 8;6(3):411-21. doi: 10.1016/j.stemcr.2016.01.002. Epub 2016 Feb 4.

GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis

Authors:
Gao X, Wu T, Johnson KD, Lahvic JL, Ranheim EA, Zon LI, Bresnick EH
Citation:
Stem Cell Reports. 2016 Mar 8;6(3):368-82. doi: 10.1016/j.stemcr.2016.01.008. Epub 2016 Feb 18
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) originate from hemogenic endothelium within the aorta-gonad-mesonephros (AGM) region of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao X, Wu T, Johnson KD, Lahvic JL, Ranheim EA, Zon LI, Bresnick EH. GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis. Stem Cell Reports. 2016 Mar 8;6(3):368-82. doi: 10.1016/j.stemcr.2016.01.008. Epub 2016 Feb 18.

Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation

Authors:
Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, Filhol E, Niel O, Silbermann F, Lebreton C, Collardeau-Frachon S, Rouvet I, Alessandri JL, Devisme L, Dieux-Coeslier A, Cordier MP, Capri Y, Khung-Savatovsky S, Sigaudy S, Salomon R, Antignac C, Gubler MC, Benmerah A, Terzi F, Attié-Bitach T, Jeanpierre C, Saunier S
Citation:
PLoS Genet. 2016 Mar 11;12(3):e1005894. doi: 10.1371/journal.pgen.1005894. eCollection 2016 Mar
Epub:
Not Epub
Abstract:
Ciliopathies are a group of genetic multi-systemic disorders related to dysfunction of the primary cilium, a sensory organelle...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, Filhol E, Niel O, Silbermann F, Lebreton C, Collardeau-Frachon S, Rouvet I, Alessandri JL, Devisme L, Dieux-Coeslier A, Cordier MP, Capri Y, Khung-Savatovsky S, Sigaudy S, Salomon R, Antignac C, Gubler MC, Benmerah A, Terzi F, Attié-Bitach T, Jeanpierre C, Saunier S. Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS Genet. 2016 Mar 11;12(3):e1005894. doi: 10.1371/journal.pgen.1005894. eCollection 2016 Mar.

PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration

Authors:
Davey CF, Mathewson AW, Moens CB
Citation:
PLoS Genet. 2016 Mar 18;12(3):e1005934. doi: 10.1371/journal.pgen.1005934. eCollection 2016 Mar
Epub:
Not Epub
Abstract:
The planar cell polarity (PCP) pathway is a cell-contact mediated mechanism for transmitting polarity information between...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davey CF, Mathewson AW, Moens CB. PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genet. 2016 Mar 18;12(3):e1005934. doi: 10.1371/journal.pgen.1005934. eCollection 2016 Mar.

ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation

Authors:
Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J
Citation:
Sci Rep. 2016 Mar 23;6:23433. doi: 10.1038/srep23433
Epub:
Not Epub
Abstract:
The lipid mediator lysophosphatidic acid (LPA) signals via six distinct G protein-coupled receptors to mediate both unique and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J. ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Sci Rep. 2016 Mar 23;6:23433. doi: 10.1038/srep23433.

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