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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Identification of microRNAs and microRNA Targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1

Authors:
Liu C, Lou CH, Shah V, Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK
Citation:
Dev Biol. 2015 Nov 5. pii: S0012-1606(15)30277-3. doi: 10.1016/j.ydbio.2015.11.005. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are known to play diverse roles in the regulation of vertebrate development. To investigate miRNA-target...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu C, Lou CH, Shah V, Ritter R, Talley J, Soibam B, Benham A, Zhu H, Perez E, Shieh YE, Gunaratne PH, Sater AK. Identification of microRNAs and microRNA Targets in Xenopus gastrulae: The role of miR-26 in the regulation of Smad1. Dev Biol. 2015 Nov 5. pii: S0012-1606(15)30277-3. doi: 10.1016/j.ydbio.2015.11.005. [Epub ahead of print].

Ancestral mesodermal reorganization and evolution of the vertebrate head

Authors:
Onai T, Aramaki T, Inomata H, Hirai T, Kuratani S
Citation:
Zoo Lett. 2015;1:29 doi:10.1186/s40851-015-0030-3
Epub:
Not Epub
Abstract:
Introduction: The vertebrate head is characterized by unsegmented head mesoderm the evolutionary origin of which remains...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Onai T, Aramaki T, Inomata H, Hirai T, Kuratani S. Ancestral mesodermal reorganization and evolution of the vertebrate head. Zoo Lett. 2015;1:29 doi:10.1186/s40851-015-0030-3.

Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways

Authors:
Noiret M, Mottier S, Angrand G, Gautier-Courteille C, Lerivray H, Viet J, Paillard L, Mereau A, Hardy S, Audic Y
Citation:
Dev Biol. 2015 Nov 3. pii: S0012-1606(15)30271-2. doi: 10.1016/j.ydbio.2015.11.002. [Epub ahead of print]
Epub:
Yes
Abstract:
In humans, genetic diseases affecting skin integrity (genodermatoses) are generally caused by mutations in a small number of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Noiret M, Mottier S, Angrand G, Gautier-Courteille C, Lerivray H, Viet J, Paillard L, Mereau A, Hardy S, Audic Y. Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways. Dev Biol. 2015 Nov 3. pii: S0012-1606(15)30271-2. doi: 10.1016/j.ydbio.2015.11.002. [Epub ahead of print].

Mutation of the mitochondrial carrier SLC25A42 causes a novel form of mitochondrial myopathy in humans

Authors:
Shamseldin HE, Smith LL, Kentab A, Alkhalidi H, Summers B, Alsedairy H, Xiong Y, Gupta VA, Alkuraya FS
Citation:
Hum Genet. 2015 Nov 5. [Epub ahead of print]
Epub:
Yes
Abstract:
Myopathies are heterogeneous disorders characterized clinically by weakness and hypotonia, usually in the absence of gross...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shamseldin HE, Smith LL, Kentab A, Alkhalidi H, Summers B, Alsedairy H, Xiong Y, Gupta VA, Alkuraya FS. Mutation of the mitochondrial carrier SLC25A42 causes a novel form of mitochondrial myopathy in humans. Hum Genet. 2015 Nov 5. [Epub ahead of print].

ACAM, a novel member of the neural IgCAM family, mediates anterior neural tube closure in a primitive chordate

Authors:
Morales Diaz H, Mejares E, Newman-Smith E, Smith WC
Citation:
Dev Biol. 2015 Nov 2. pii: S0012-1606(15)30191-3. doi: 10.1016/j.ydbio.2015.10.032. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The neural IgCAM family of cell adhesion molecules, which includes NCAM and related molecules, has evolved via gene duplication...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Morales Diaz H, Mejares E, Newman-Smith E, Smith WC. ACAM, a novel member of the neural IgCAM family, mediates anterior neural tube closure in a primitive chordate. Dev Biol. 2015 Nov 2. pii: S0012-1606(15)30191-3. doi: 10.1016/j.ydbio.2015.10.032. [Epub ahead of print].

microRNA-31 modulates skeletal patterning in the sea urchin embryo

Authors:
Stepicheva NA, Song JL
Citation:
Development. 2015 Nov 1;142(21):3769-80. doi: 10.1242/dev.127969. Epub 2015 Sep 23
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that repress the translation and reduce the stability of target mRNAs in animal...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Stepicheva NA, Song JL. microRNA-31 modulates skeletal patterning in the sea urchin embryo. Development. 2015 Nov 1;142(21):3769-80. doi: 10.1242/dev.127969. Epub 2015 Sep 23.

CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus

Authors:
Bhattacharya D, Marfo CA, Li D, Lane M, Khokha MK
Citation:
Dev Biol. 2015 Nov 4. pii: S0012-1606(15)30269-4. doi: 10.1016/j.ydbio.2015.11.003. [Epub ahead of print]
Epub:
Yes
Abstract:
Congenital malformations are the major cause of infant mortality in the US and Europe. Due to rapid advances in human genomics...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Bhattacharya D, Marfo CA, Li D, Lane M, Khokha MK. CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus. Dev Biol. 2015 Nov 4. pii: S0012-1606(15)30269-4. doi: 10.1016/j.ydbio.2015.11.003. [Epub ahead of print].

Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin–Siris syndrome

Authors:
Hempel A, Pagnamenta AT, Blyth M, Mansour S, McConnell V, Kou I, Shiro I, Tsurusaki Y, Matsumoto N, Lo-Castro A, Plessis G, Albrecht B, Battaglia A, Taylor JC, Howard MF, Keays D, Sohal AS, DDD collaboration, Kühl SJ, Kini U, McNeill A
Citation:
J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2015-103393
Epub:
Yes
Abstract:
Background: SOX11 is a transcription factor proposed to play a role in brain development. The relevance of SOX11 to human...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hempel A, Pagnamenta AT, Blyth M, Mansour S, McConnell V, Kou I, Shiro I, Tsurusaki Y, Matsumoto N, Lo-Castro A, Plessis G, Albrecht B, Battaglia A, Taylor JC, Howard MF, Keays D, Sohal AS, DDD collaboration, Kühl SJ, Kini U, McNeill A. Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin–Siris syndrome. J Med Genet. 2015;[Epub ahead of print] doi:10.1136/jmedgenet-2015-103393 .

Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived Conditions

Authors:
Pirson M, Debrulle S, Clippe A, Clotman F, Knoops B
Citation:
PLoS One. 2015 Nov 5;10(11):e0142280. doi: 10.1371/journal.pone.0142280. eCollection 2015
Epub:
Not Epub
Abstract:
Thioredoxin-2 (Trx2) is a mitochondrial protein using a dithiol active site to reduce protein disulfides. In addition to the...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Pirson M, Debrulle S, Clippe A, Clotman F, Knoops B. Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived Conditions. PLoS One. 2015 Nov 5;10(11):e0142280. doi: 10.1371/journal.pone.0142280. eCollection 2015.

CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart

Authors:
Matrone G, Wilson KS, Maqsood S, Mullins JJ, Tucker CS, Denvir MA
Citation:
J Cell Sci. 2015:[Epub aheaed of print] doi:10.1242/jcs.175018
Epub:
Yes
Abstract:
Cyclin Dependent Kinase (CDK)9 acts via the Positive Transcription Elongation Factor-b (P-TEFb) complex to activate and expand...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matrone G, Wilson KS, Maqsood S, Mullins JJ, Tucker CS, Denvir MA. CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart. J Cell Sci. 2015:[Epub aheaed of print] doi:10.1242/jcs.175018.

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