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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3
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Citation:
Proc Natl Acad Sci U S A. 2015 Nov 4. pii: 201510495. [Epub ahead of print] Epub:
Yes Abstract:
Three genes, CCM1, CCM2, and CCM3, interact genetically and biochemically and are mutated in cerebral cavernous malformations (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cullere X, Plovie E, Bennett PM, MacRae CA, Mayadas TN. The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3. Proc Natl Acad Sci U S A. 2015 Nov 4. pii: 201510495. [Epub ahead of print]. |
Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of Left-Right asymmetry
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Citation:
Mol Biol Cell. 2015;[epub ahead of print] doi:10.1091/mbc.E15-07-0474 Epub:
Yes Abstract:
The establishment of Left-Right asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Silva E, Betleja E, John E, Spear P, Moresco JJ, Zhang S, Yates JR III, Mitchell BJ, Mahjoub MR. Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of Left-Right asymmetry. Mol Biol Cell. 2015;[epub ahead of print] doi:10.1091/mbc.E15-07-0474. |
Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213
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Citation:
Sci Rep. 2015;5:16161. doi:10.1038/srep16161 Epub:
Not Epub Abstract:
Mysterin (also known as RNF213) is a huge intracellular protein with two AAA+ ATPase modules and a RING finger ubiquitin ligase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kotani Y, Morito D, Yamazaki S, Ogino K, Kawakami K, Takashima S, Hirata H, Nagata K. Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213. Sci Rep. 2015;5:16161. doi:10.1038/srep16161. |
A human laterality disorder caused by a homozygous deleterious mutation in MMP21
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Citation:
J Med Genet. 2015 Oct 1. pii: jmedgenet-2015-103336. doi: 10.1136/jmedgenet-2015-103336. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Laterality in the vertebrate embryo is determined by left-right asymmetric gene expression driven by the flow of... Organism or Cell Type:
zebrafish Citation Extract: Perles Z, Moon S, Ta-Shma A, Yaacov B, Francescatto L, Edvardson S, Rein AJ, Elpeleg O, Katsanis N. A human laterality disorder caused by a homozygous deleterious mutation in MMP21. J Med Genet. 2015 Oct 1. pii: jmedgenet-2015-103336. doi: 10.1136/jmedgenet-2015-103336. [Epub ahead of print]. |
Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome
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Citation:
Hum Mol Genet. 2015 Sep 18. pii: ddv388. [Epub ahead of print] Epub:
Yes Abstract:
SPOAN syndrome is a neurodegenerative disorder mainly characterized by spastic paraplegia, optic atrophy and neuropathy (SPOAN... Organism or Cell Type:
zebrafish Citation Extract: Melo US, Macedo-Souza LI, Figueiredo T, Muotri AR, Gleeson JG, Coux G, Armas P, Calcaterra NB, Kitajima JP, Amorim S, Olávio TR, Griesi-Oliveira K, Coatti GC, Rocha CR, Martins-Pinheiro M, Menck CF, Zaki MS, Kok F, Zatz M, Santos S. Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome. Hum Mol Genet. 2015 Sep 18. pii: ddv388. [Epub ahead of print]. |
Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN)
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Citation:
J Med Genet. 2015 Nov;52(11):738-48. doi: 10.1136/jmedgenet-2015-103292. Epub 2015 Sep 4 Epub:
Not Epub Abstract:
BACKGROUND: Deadenylation regulates RNA function and fate. Poly(A)-specific ribonuclease (PARN) is a deadenylase that processes... Organism or Cell Type:
zebrafish Citation Extract: Dhanraj S, Gunja SM, Deveau AP, Nissbeck M, Boonyawat B, Coombs AJ, Renieri A, Mucciolo M, Marozza A, Buoni S, Turner L, Li H, Jarrar A, Sabanayagam M, Kirby M, Shago M, Pinto D, Berman JN, Scherer SW, Virtanen A, Dror Y. Bone marrow failure and developmental delay caused by mutations in poly(A)-specific ribonuclease (PARN). J Med Genet. 2015 Nov;52(11):738-48. doi: 10.1136/jmedgenet-2015-103292. Epub 2015 Sep 4. |
Modulating expression level of secreted Wnt3 influences cerebellum development in zebrafish transgenics
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Citation:
Development. 2015 Sep 22. pii: dev.127589. [Epub ahead of print] Epub:
Not Epub Abstract:
The boundaries of brain regions are associated with the tissue-specific secretion of ligands from different signalling pathways... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Teh C, Sun G, Shen H, Korzh V, Wohland T. Modulating expression level of secreted Wnt3 influences cerebellum development in zebrafish transgenics. Development. 2015 Sep 22. pii: dev.127589. [Epub ahead of print]. |
DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint
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Citation:
Nat Comm. 2015;6:8553. doi:10.1038/ncomms9553 Epub:
Not Epub Abstract:
Extensive damage to maternal DNA during meiosis causes infertility, birth defects and abortions. However, it is unknown if... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Collins JK,. Lane SIR, Merriman JA, Jones KT. DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint. Nat Comm. 2015;6:8553. doi:10.1038/ncomms9553. |
DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age
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Citation:
Nat Comm. 2015;6:8706. doi:10.1038/ncomms9706 Epub:
Not Epub Abstract:
In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to infertility and developmental... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Marangos P, Stevense M, Niaka K, Lagoudaki M, Nabti I, Jessberger R, John Carroll J. DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age. Nat Comm. 2015;6:8706. doi:10.1038/ncomms9706. |
Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development
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Citation:
Mol Biol Cell. 2015 Nov 1;26(21):3728-40. doi: 10.1091/mbc.E15-02-0112. Epub 2015 Sep 9 Epub:
Not Epub Abstract:
During development, vagal neural crest cells fated to contribute to the enteric nervous system migrate ventrally away from the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Uribe RA, Bronner ME. Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development. Mol Biol Cell. 2015 Nov 1;26(21):3728-40. doi: 10.1091/mbc.E15-02-0112. Epub 2015 Sep 9. |