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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Characterization of the three zebrafish orthologs of the mitochondrial GTPase Miro/Rhot

Authors:
Hollister BM, Oonk KA, Weiser DC, Walsh S
Citation:
Comp Biochem Physiol B Biochem Mol Biol. 2015 Oct 16. pii: S1096-4959(15)00184-0. doi: 10.1016/j.cbpb.2015.10.006
Epub:
Yes
Abstract:
Mitochondria exhibit dynamic locomotion and spatial rearrangement. This movement is necessary for a cell to maintain basic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hollister BM, Oonk KA, Weiser DC, Walsh S. Characterization of the three zebrafish orthologs of the mitochondrial GTPase Miro/Rhot. Comp Biochem Physiol B Biochem Mol Biol. 2015 Oct 16. pii: S1096-4959(15)00184-0. doi: 10.1016/j.cbpb.2015.10.006.

Thyroid development in zebrafish lacking Taz

Authors:
Pappalardo A, Porreca I, Caputi L, De Felice E, Schulte-Merker S, Zannini M, Sordino P
Citation:
Mech Dev. 2015 Oct 15. pii: S0925-4773(15)30031-9. doi: 10.1016/j.mod.2015.10.002. [Epub ahead of print]
Epub:
Yes
Abstract:
Taz is a signal-responsive transcriptional coregulator implicated in several biological functions, from chondrogenesis to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pappalardo A, Porreca I, Caputi L, De Felice E, Schulte-Merker S, Zannini M, Sordino P. Thyroid development in zebrafish lacking Taz. Mech Dev. 2015 Oct 15. pii: S0925-4773(15)30031-9. doi: 10.1016/j.mod.2015.10.002. [Epub ahead of print].

Synaptic vesicles contain small ribonucleic acids (sRNAs) including transfer RNA fragments (trfRNA) and microRNAs (miRNA)

Authors:
Li H, Wu C, Aramayo R, Sachs MS, Harlow ML
Citation:
Sci Rep. 2015 Oct 8;5:14918. doi: 10.1038/srep14918
Epub:
Not Epub
Abstract:
Synaptic vesicles (SVs) are neuronal presynaptic organelles that load and release neurotransmitter at chemical synapses. In...
Citation Extract:
Li H, Wu C, Aramayo R, Sachs MS, Harlow ML. Synaptic vesicles contain small ribonucleic acids (sRNAs) including transfer RNA fragments (trfRNA) and microRNAs (miRNA). Sci Rep. 2015 Oct 8;5:14918. doi: 10.1038/srep14918.

IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3

Authors:
Mailer RK, Joly AL, Liu S, Elias S, Tegner J, Andersson J
Citation:
Sci Rep. 2015 Oct 6;5:14674. doi: 10.1038/srep14674
Epub:
Not Epub
Abstract:
CD4(+)FOXP3(+) regulatory T (Treg) cells are essential for maintaining immunological self-tolerance. Treg cell development and...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: primary T cells
Citation Extract:
Mailer RK, Joly AL, Liu S, Elias S, Tegner J, Andersson J. IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3. Sci Rep. 2015 Oct 6;5:14674. doi: 10.1038/srep14674.

A Zebrafish Drug-Repurposing Screen Reveals sGC-Dependent and sGC-Independent Pro-Inflammatory Activities of Nitric Oxide

Authors:
Wittmann C, Reischl M, Shah AH, Kronfuss E, Mikut R, Liebel U, Grabher C
Citation:
PLoS One. 2015 Oct 7;10(10):e0137286. doi: 10.1371/journal.pone.0137286. eCollection 2015
Epub:
Not Epub
Abstract:
Tissue injury and infection trigger innate immune responses. However, dysregulation may result in chronic inflammation and is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wittmann C, Reischl M, Shah AH, Kronfuss E, Mikut R, Liebel U, Grabher C. A Zebrafish Drug-Repurposing Screen Reveals sGC-Dependent and sGC-Independent Pro-Inflammatory Activities of Nitric Oxide. PLoS One. 2015 Oct 7;10(10):e0137286. doi: 10.1371/journal.pone.0137286. eCollection 2015.

The alternative splicing factor Nova2 regulates vascular development and lumen formation

Authors:
Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, Fredrickx E, Taveggia C, Wyatt CD, Irimia M, Di Fiore PP, Blencowe BJ, Dejana E, Ghigna C
Citation:
Nat Commun. 2015 Oct 8;6:8479. doi: 10.1038/ncomms9479
Epub:
Not Epub
Abstract:
Vascular lumen formation is a fundamental step during angiogenesis; yet, the molecular mechanisms underlying this process are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, Fredrickx E, Taveggia C, Wyatt CD, Irimia M, Di Fiore PP, Blencowe BJ, Dejana E, Ghigna C. The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nat Commun. 2015 Oct 8;6:8479. doi: 10.1038/ncomms9479.

Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease

Authors:
Zizioli D, Tiso N, Guglielmi A, Saraceno C, Busolin G, Giuliani R, Khatri D, Monti E, Borsani G, Argenton F, Finazzi D
Citation:
Neurobiol Dis. 2015 Oct 14. pii: S0969-9961(15)30068-1. doi: 10.1016/j.nbd.2015.10.010. [Epub ahead of print]
Epub:
Yes
Abstract:
Pantothenate Kinase Associated Neurodegeneration (PKAN) is an autosomal recessive disorder with mutations in the pantothenate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zizioli D, Tiso N, Guglielmi A, Saraceno C, Busolin G, Giuliani R, Khatri D, Monti E, Borsani G, Argenton F, Finazzi D. Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease. Neurobiol Dis. 2015 Oct 14. pii: S0969-9961(15)30068-1. doi: 10.1016/j.nbd.2015.10.010. [Epub ahead of print].

Pronephric tubule morphogenesis in zebrafish depends on mnx mediated repression of irx1b within the intermediate mesoderm

Authors:
Ott E, Wendik B, Srivastava M, Pacho F, Töchterle S, Salvenmoser W, Meyer D
Citation:
Dev Biol. 2015 Oct 12. pii: S0012-1606(15)30237-2. doi: 10.1016/j.ydbio.2015.10.014. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in the homeobox transcription factor MNX1 are the major cause of dominantly inherited sacral agenesis. Studies in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ott E, Wendik B, Srivastava M, Pacho F, Töchterle S, Salvenmoser W, Meyer D. Pronephric tubule morphogenesis in zebrafish depends on mnx mediated repression of irx1b within the intermediate mesoderm. Dev Biol. 2015 Oct 12. pii: S0012-1606(15)30237-2. doi: 10.1016/j.ydbio.2015.10.014. [Epub ahead of print].

Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish

Authors:
Zhang C, Anderson A, Cole GJ
Citation:
Birth Defects Res A Clin Mol Teratol. 2015 Oct 16. doi: 10.1002/bdra.23460. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Ethanol is a teratogen affecting numerous regions of the developing nervous system. The present study was...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang C, Anderson A, Cole GJ. Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish. Birth Defects Res A Clin Mol Teratol. 2015 Oct 16. doi: 10.1002/bdra.23460. [Epub ahead of print].

Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway

Authors:
Reinardy JL, Corey DM, Golzio C, Mueller SB, Katsanis N, Kontos CD
Citation:
PLoS One. 2015 Oct 5;10(10):e0139614. doi: 10.1371/journal.pone.0139614. eCollection 2015
Epub:
Not Epub
Abstract:
The endothelial receptor tyrosine kinase (RTK) Tie1 was discovered over 20 years ago, yet its precise function and mode of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reinardy JL, Corey DM, Golzio C, Mueller SB, Katsanis N, Kontos CD. Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway. PLoS One. 2015 Oct 5;10(10):e0139614. doi: 10.1371/journal.pone.0139614. eCollection 2015.

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