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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Enhancement of Blood-Brain Barrier Permeability and Delivery of Antisense Oligonucleotides or Plasmid DNA to the Brain by the Combination of Bubble Liposomes and High-Intensity Focused Ultrasound
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Citation:
Pharmaceutics. 2015 Sep 21;7(3):344-62. doi: 10.3390/pharmaceutics7030344 Epub:
Not Epub Abstract:
The blood-brain barrier (BBB) is a major obstacle that prevents therapeutic drugs or genes from being delivered to the central... Delivery Method:
bubble liposomes and ultrasound Organism or Cell Type:
mice Citation Extract: Negishi Y, Yamane M, Kurihara N, Endo-Takahashi Y, Sashida S, Takagi N, Suzuki R, Maruyama K. Enhancement of Blood-Brain Barrier Permeability and Delivery of Antisense Oligonucleotides or Plasmid DNA to the Brain by the Combination of Bubble Liposomes and High-Intensity Focused Ultrasound. Pharmaceutics. 2015 Sep 21;7(3):344-62. doi: 10.3390/pharmaceutics7030344. |
Müller glia provide essential tensile strength to the developing retina
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Citation:
J Cell Biol. 2015 Sep 28;210(7):1075-83. doi: 10.1083/jcb.201503115 Epub:
Not Epub Abstract:
To investigate the cellular basis of tissue integrity in a vertebrate central nervous system (CNS) tissue, we eliminated Müller... Organism or Cell Type:
zebrafish Citation Extract: MacDonald RB, Randlett O, Oswald J, Yoshimatsu T, Franze K, Harris WA. Müller glia provide essential tensile strength to the developing retina. J Cell Biol. 2015 Sep 28;210(7):1075-83. doi: 10.1083/jcb.201503115. |
PTEN regulates cilia through Dishevelled
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Citation:
Nat Commun. 2015 Sep 24;6:8388. doi: 10.1038/ncomms9388 Epub:
Not Epub Abstract:
Cilia are hair-like cellular protrusions important in many aspects of eukaryotic biology. For instance, motile cilia enable... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Shnitsar I, Bashkurov M, Masson GR, Ogunjimi AA, Mosessian S, Cabeza EA, Hirsch CL, Trcka D, Gish G, Jiao J, Wu H, Winklbauer R, Williams RL, Pelletier L, Wrana JL, Barrios-Rodiles M. PTEN regulates cilia through Dishevelled. Nat Commun. 2015 Sep 24;6:8388. doi: 10.1038/ncomms9388. |
The aPKC/Par3/Par6 polarity complex and membrane order are functionally inter-dependent in epithelia during vertebrate organogenesis
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Citation:
Traffic. 2015 Oct 12. doi: 10.1111/tra.12339. [Epub ahead of print] Epub:
Yes Abstract:
The differential distribution of lipids between apical and basolateral membranes is necessary for many epithelial cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Abu-Siniyeh A, Owen DM, Benzing C, Rinkwitz S, Becker TS, Majumdar A, Gaus K. The aPKC/Par3/Par6 polarity complex and membrane order are functionally inter-dependent in epithelia during vertebrate organogenesis. Traffic. 2015 Oct 12. doi: 10.1111/tra.12339. [Epub ahead of print]. |
Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism
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Citation:
Mol Psychiatry. 2015 Sep 15. doi: 10.1038/mp.2015.139. [Epub ahead of print] Epub:
Yes Abstract:
Autism spectrum disorder (ASD) is a common neurodevelopmental condition characterized by marked genetic heterogeneity. Recent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pilorge M, Fassier C, Le Corronc H, Potey A, Bai J, De Gois S, Delaby E, Assouline B, Guinchat V, Devillard F, Delorme R, Nygren G, Råstam M, Meier JC, Otani S, Cheval H, James VM, Topf M, Dear TN, Gillberg C, Leboyer M, Giros B, Gautron S, Hazan J, Harvey RJ, Legendre P, Betancur C. Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Mol Psychiatry. 2015 Sep 15. doi: 10.1038/mp.2015.139. [Epub ahead of print]. |
The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product
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Citation:
Eur J Hum Genet. 2015 Sep 16. doi: 10.1038/ejhg.2015.199. [Epub ahead of print] Epub:
Yes Abstract:
Nephronophthisis (NPH) is a rare autosomal ciliopathy, but the leading cause for hereditary end-stage renal disease in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramachandran H, Yakulov TA, Engel C, Müller B, Walz G. The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product. Eur J Hum Genet. 2015 Sep 16. doi: 10.1038/ejhg.2015.199. [Epub ahead of print]. |
The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product
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Citation:
Eur J Hum Genet. 2015 Sep 16. doi: 10.1038/ejhg.2015.199. [Epub ahead of print] Epub:
Yes Abstract:
Nephronophthisis (NPH) is a rare autosomal ciliopathy, but the leading cause for hereditary end-stage renal disease in children... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramachandran H, Yakulov TA, Engel C, Müller B, Walz G. The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product. Eur J Hum Genet. 2015 Sep 16. doi: 10.1038/ejhg.2015.199. [Epub ahead of print]. |
Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish
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Citation:
Cell Discov. 2015;1:15027. doi:10.1038/celldisc.2015.27 Epub:
Not Epub Abstract:
Hematopoietic stem and progenitor cells have the capacity to self-renew and differentiate into all blood cell lineages, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu X, Wei Y, Liu F. Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish. Cell Discov. 2015;1:15027. doi:10.1038/celldisc.2015.27. |
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability
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Citation:
Sci Rep. 2015 Sep 14;5:13989. doi: 10.1038/srep13989 Epub:
Not Epub Abstract:
Mitochondria are involved in key cellular functions including energy production, metabolic homeostasis, and apoptosis. Normal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bohovych I, Fernandez MR, Rahn JJ, Stackley KD, Bestman JE, Anandhan A, Franco R, Claypool SM, Lewis RE, Chan SS, Khalimonchuk O . Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability. Sci Rep. 2015 Sep 14;5:13989. doi: 10.1038/srep13989. |
Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators
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Citation:
Genomics Data. 2015;6:199-201. doi:j.gdata.2015.09.015 Epub:
Not Epub Abstract:
The vertebrate heart develops from two distinct lineages of cardiomyocytes that arise from the first and second heart fields (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Musso G, Mosimann C, Panáková D, Burger A, Zhou Y, Zon LI, MacRae CA. Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators. Genomics Data. 2015;6:199-201. doi:j.gdata.2015.09.015. |