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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12165 scientific papers returned from the database with the search filters currently being used below.
There are 12165 scientific papers returned from the database with the search filters currently being used below.
The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR
Citation:
Biol Open. 2015 Oct 2. pii: bio.014076. doi: 10.1242/bio.014076. [Epub ahead of print] Epub:
Not Epub Abstract:
In autosomal dominant polycystic kidney disease (ADPKD), cyst inflation and continuous enlargement are associated with marked... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roxo-Rosa M, Jacinto R, Sampaio P, Lopes SS. The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR. Biol Open. 2015 Oct 2. pii: bio.014076. doi: 10.1242/bio.014076. [Epub ahead of print]. |
Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion
Citation:
MBio. 2015 Sep 29;6(5). pii: e01425-15. doi: 10.1128/mBio.01425-15 Epub:
Not Epub Abstract:
The human fungal pathogen Cryptococcus neoformans is capable of infecting a broad range of hosts, from invertebrates like... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tenor JL, Oehlers SH, Yang JL, Tobin DM, Perfect JR. Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion. MBio. 2015 Sep 29;6(5). pii: e01425-15. doi: 10.1128/mBio.01425-15. |
Phosphorylation of heterogeneous nuclear ribonucleoprotein K at an extracellular signal-regulated kinase phosphorylation site promotes neurofilament-medium protein expression and axon outgrowth in Xenopus
Citation:
Neurosci Lett. 2015 Sep 26;607:59-65. doi: 10.1016/j.neulet.2015.09.027. [Epub ahead of print] Epub:
Not Epub Abstract:
Post-transcriptional control of cytoskeletal genes fine-tunes the supply of structural materials to growing axons in response... Organism or Cell Type:
Xenopus laevis Citation Extract: Hutchins EJ, Belrose JL, Szaro BG. Phosphorylation of heterogeneous nuclear ribonucleoprotein K at an extracellular signal-regulated kinase phosphorylation site promotes neurofilament-medium protein expression and axon outgrowth in Xenopus. Neurosci Lett. 2015 Sep 26;607:59-65. doi: 10.1016/j.neulet.2015.09.027. [Epub ahead of print]. |
Gene Editing Versus Morphants
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Zebrafish. 2015 Oct;12(5):319. doi: 10.1089/zeb.2015.1114 Epub:
Not Epub Abstract:
No abstract available.
Organism or Cell Type:
zebrafish Citation Extract: Morcos PA, Vincent AC, Moulton JD. Gene Editing Versus Morphants. Zebrafish. 2015 Oct;12(5):319. doi: 10.1089/zeb.2015.1114. |
MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates
Citation:
Nat Genet. 2015 Oct 5. doi: 10.1038/ng.3376. [Epub ahead of print] Epub:
Yes Abstract:
Heterotaxy results from a failure to establish normal left-right asymmetry early in embryonic development. By whole-exome... Organism or Cell Type:
zebrafish Citation Extract: Guimier A, Gabriel GC, Bajolle F, Tsang M, Liu H, Noll A, Schwartz M, El Malti R, Smith LD, Klena NT, Jimenez G, Miller NA, Oufadem M, Moreau de Bellaing A, Yagi H, Saunders CJ, Baker CN, Di Filippo S, Peterson KA, Thiffault I, Bole-Feysot C, Cooley LD, Farrow EG, Masson C, Schoen P, Deleuze JF, Nitschké P, Lyonnet S, de Pontual L, Murray SA, Bonnet D, Kingsmore SF, Amiel J, Bouvagnet P, Lo CW, Gordon CT. MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates. Nat Genet. 2015 Oct 5. doi: 10.1038/ng.3376. [Epub ahead of print]. |
The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway
Citation:
Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438 Epub:
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Small leucine-rich repeat proteoglycan (SLRP) family proteins play important roles in a number of biological events. Here, we... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway. Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438. |
Peptide Nucleic Acid Promotes Systemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice
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Mol Ther Nucleic Acids. 2015 Oct 6;4:e255. doi: 10.1038/mtna.2015.27 Epub:
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Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise for Duchenne muscular dystrophy (DMD)... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Gao X, Shen X, Dong X, Ran N, Han G, Cao L, Gu B, Yin H. Peptide Nucleic Acid Promotes Systemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice. Mol Ther Nucleic Acids. 2015 Oct 6;4:e255. doi: 10.1038/mtna.2015.27. |
Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish
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PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015. |
Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?
Citation:
Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6 Epub:
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Limb body wall complex (LBWC) and amniotic band sequence (ABS) are multiple congenital anomaly conditions with craniofacial,... Organism or Cell Type:
zebrafish Citation Extract: Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M. Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?. Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6. |
Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β
Citation:
Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print] Epub:
Not Epub Abstract:
6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) is both a polybrominated diphenyl ether (PBDE) flame... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, Stapleton HM. Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β. Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print]. |