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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12165 scientific papers returned from the database with the search filters currently being used below.
There are 12165 scientific papers returned from the database with the search filters currently being used below.
Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia
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Citation:
Am J Hum Genet. 2015 Sep 9. pii: S0002-9297(15)00331-6. doi: 10.1016/j.ajhg.2015.08.009. [Epub ahead of print] Epub:
Yes Abstract:
The evolutionarily conserved transmembrane anterior posterior transformation 1 protein, encoded by TAPT1, is involved in murine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Symoens S, Barnes AM, Gistelinck C, Malfait F, Guillemyn B, Steyaert W, Syx D, D'hondt S, Biervliet M, De Backer J, Witten EP, Leikin S, Makareeva E, Gillessen-Kaesbach G, Huysseune A, Vleminckx K, Willaert A, De Paepe A, Marini JC, Coucke PJ. Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia. Am J Hum Genet. 2015 Sep 9. pii: S0002-9297(15)00331-6. doi: 10.1016/j.ajhg.2015.08.009. [Epub ahead of print]. |
Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation
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Citation:
Stem Cell Reports. 2015 Sep 9. pii: S2213-6711(15)00244-1. doi: 10.1016/j.stemcr.2015.08.010. [Epub ahead of print] Epub:
Yes Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are born from hemogenic endothelium in the dorsal aorta. Specification of this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 2015 Sep 9. pii: S2213-6711(15)00244-1. doi: 10.1016/j.stemcr.2015.08.010. [Epub ahead of print]. |
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation
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Citation:
Nat Cell Biol. 2015 Mar;17(3):228-40. doi: 10.1038/ncb3109. Epub 2015 Feb 16. Erratum in: Nat Cell Biol. 2015 Apr;17(4):531 Epub:
Not Epub Abstract:
Membrane association with mother centriole (M-centriole) distal appendages is critical for ciliogenesis initiation. How the Rab... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu Q, Insinna C, Ott C, Stauffer J, Pintado PA, Rahajeng J, Baxa U, Walia V, Cuenca A, Hwang YS, Daar IO, Lopes S, Lippincott-Schwartz J, Jackson PK, Caplan S, Westlake CJ. Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation. Nat Cell Biol. 2015 Mar;17(3):228-40. doi: 10.1038/ncb3109. Epub 2015 Feb 16. Erratum in: Nat Cell Biol. 2015 Apr;17(4):531. |
Yap and Taz regulate retinal pigment epithelial cell fate
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Citation:
Development. 2015 Sep 1;142(17):3021-32. doi: 10.1242/dev.119008. Epub 2015 Jul 24 Epub:
Not Epub Abstract:
The optic vesicle comprises a pool of bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Miesfeld JB, Gestri G, Clark BS, Flinn MA, Poole RJ, Bader JR, Besharse JC, Wilson SW, Link BA. Yap and Taz regulate retinal pigment epithelial cell fate. Development. 2015 Sep 1;142(17):3021-32. doi: 10.1242/dev.119008. Epub 2015 Jul 24. |
Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish
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Citation:
Elife. 2015 Sep 3;4. doi: 10.7554/eLife.08201. [Epub ahead of print] Epub:
Not Epub Abstract:
During development, proliferation must be tightly controlled for organs to reach their appropriate size. While the Hippo... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Agarwala S, Duquesne S, Liu K, Boehm A, Grimm L, Link S, König S, Eimer S, Ronneberger O, Lecaudey V. Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish. Elife. 2015 Sep 3;4. doi: 10.7554/eLife.08201. [Epub ahead of print]. |
The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo
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Citation:
PLoS Biol. 2015 Sep 9;13(9):e1002247. doi: 10.1371/journal.pbio.1002247. eCollection 2015 Sep Epub:
Not Epub Abstract:
Specification of the dorsal-ventral axis in the highly regulative sea urchin embryo critically relies on the zygotic expression... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Haillot E, Molina MD, Lapraz F, Lepage T. The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo. PLoS Biol. 2015 Sep 9;13(9):e1002247. doi: 10.1371/journal.pbio.1002247. eCollection 2015 Sep. |
Panorama of ancient metazoan macromolecular complexes
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Citation:
Nature. 2015 Sep 7. doi: 10.1038/nature14877. [Epub ahead of print] Epub:
Yes Abstract:
Macromolecular complexes are essential to conserved biological processes, but their prevalence across animals is unclear. By... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wan C, Borgeson B, Phanse S, Tu F, Drew K, Clark G, Xiong X, Kagan O, Kwan J, Bezginov A, Chessman K, Pal S, Cromar G, Papoulas O, Ni Z, Boutz DR, Stoilova S, Havugimana PC, Guo X, Malty RH, Sarov M, Greenblatt J, Babu M, Derry WB, R Tillier E, Wallingford JB, Parkinson J, Marcotte EM, Emili A. Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 7. doi: 10.1038/nature14877. [Epub ahead of print]. |
A cationic morpholino antisense oligomer conjugate: synthesis, cellular uptake and inhibition of Gli1 in the hedgehog signalling pathway
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Citation:
RSC Adv. 2014. 4:1951-1954. doi:10.1039/C3RA45257C Epub:
Not Epub Abstract:
A guanidinium-linked morpholino pentamer is synthesized and evaluated for cellular penetration properties. A regular morpholino... Organism or Cell Type:
cell culture Citation Extract: Pattanayak S, Khatra H, Sahab S, Sinha S. A cationic morpholino antisense oligomer conjugate: synthesis, cellular uptake and inhibition of Gli1 in the hedgehog signalling pathway. RSC Adv. 2014. 4:1951-1954. doi:10.1039/C3RA45257C . |
Synthesis of morpholino monomers, chlorophosphoramidate monomers, and solid-phase synthesis of short morpholino oligomers
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Citation:
Curr Protoc Nucleic Acid Chem. 2015;62:4.65.1-4.65.26. doi: 10.1002/0471142700.nc0465s62 Epub:
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Phosphorodiamidate morpholino oligomers (PMOs) are a highly capable class of synthetic antisense oligonucleotides that are used... Citation Extract: Bhadra J, Pattanayak S, Sinha S. Synthesis of morpholino monomers, chlorophosphoramidate monomers, and solid-phase synthesis of short morpholino oligomers. Curr Protoc Nucleic Acid Chem. 2015;62:4.65.1-4.65.26. doi: 10.1002/0471142700.nc0465s62. |
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome
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Citation:
J Clin Invest. 2015 Sep 1;125(9):3657-66. doi: 10.1172/JCI80657. Epub 2015 Aug 24 Epub:
Not Epub Abstract:
Juvenile ciliopathy syndromes that are associated with renal cysts and premature renal failure are commonly the result of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Slaats GG, Saldivar JC, Bacal J, Zeman MK, Kile AC, Hynes AM, Srivastava S, Nazmutdinova J, Ouden Kd, Zagers MS, Foletto V, Verhaar MC, Miles C, Sayer JA, Cimprich KA, Giles RH. DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome. J Clin Invest. 2015 Sep 1;125(9):3657-66. doi: 10.1172/JCI80657. Epub 2015 Aug 24. |