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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic response
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Citation:
Hum Mol Genet. 2015 Aug 11. pii: ddv329. [Epub ahead of print] Epub:
Yes Abstract:
The human SMN2 transgenic mice are well-established models of spinal muscular atrophy (SMA). While the severe type I mouse... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Zhou H, Meng J, Marrosu E, Janghra N, Morgan J, Muntoni F. Repeated low doses of morpholino antisense oligomer: an intermediate mouse model of spinal muscular atrophy to explore the window of therapeutic response. Hum Mol Genet. 2015 Aug 11. pii: ddv329. [Epub ahead of print]. |
Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models
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Citation:
Sci Rep. 2015;5:12727 doi:10.1038/srep12727 Epub:
Not Epub Abstract:
Chikungunya virus (CHIKV) infection in human is associated with debilitating and persistent arthralgia and arthritis. Currently... Delivery Method:
Endo-Porter(cultures) and Vivo-Morpholino(mice) Organism or Cell Type:
cell culture: HeLa, BHK, C6/36(mosquito) and mice Citation Extract: Lam S, Chen H, Chen CK, Min N, Chu JJH. Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models. Sci Rep. 2015;5:12727 doi:10.1038/srep12727. |
Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart
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Citation:
Mol Cell Endocrinol. 2015 Jul 25. pii: S0303-7207(15)30032-0. doi: 10.1016/j.mce.2015.07.025. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Transient early-life perturbations in glucocorticoids (GC) are linked with cardiovascular disease risk in later... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilson KS, Baily J, Tucker CS, Matrone G, Vass S, Moran C, Chapman KE, Mullins JJ, Kenyon C, Hadoke PW, Denvir MA. Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart. Mol Cell Endocrinol. 2015 Jul 25. pii: S0303-7207(15)30032-0. doi: 10.1016/j.mce.2015.07.025. [Epub ahead of print]. |
Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish
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Citation:
PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015 Epub:
Not Epub Abstract:
Carbonic anhydrase related proteins (CARPs) X and XI are highly conserved across species and are predominantly expressed in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Aspatwar A, Tolvanen ME, Ojanen MJ, Barker HR, Saralahti AK, Bäuerlein CA, Ortutay C, Pan P, Kuuslahti M, Parikka M, Rämet M, Parkkila S. Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish. PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015. |
Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses
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Citation:
PNAS USA. 2015;112(30):E4075-E4084. doi:10.1073/pnas.1509845112 Epub:
Not Epub Abstract:
This work provides direct evidence of evolutionary rewiring of gene-regulatory circuitry accompanying divergence of two... Delivery Method:
microinjection Organism or Cell Type:
Eucidaris tribuloides (sea urchin) Citation Extract: Erkenbrack EM, Davidson EH. Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses. PNAS USA. 2015;112(30):E4075-E4084. doi:10.1073/pnas.1509845112. |
Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm
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Citation:
eLife. 2015;10.7554/eLife.07343 Epub:
Not Epub Abstract:
Evolutionary origin of muscle is a central question when discussing mesoderm evolution. Developmental mechanisms underlying... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Andrikou C, Pai C-Y, Su Y-S, Arnone MI. Logics and properties of a genetic regulatory program that drives embryonic muscle development in an echinoderm. eLife. 2015;10.7554/eLife.07343. |
Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations
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Citation:
Cardiovasc Res. 2015 Jul 1;107(1):143-52. doi: 10.1093/cvr/cvv148. Epub 2015 May 12 Epub:
Not Epub Abstract:
AIMS: Notch and activin receptor-like kinase 1 (ALK1) have been implicated in arterial specification, angiogenic tip/stalk cell... Organism or Cell Type:
zebrafish Citation Extract: Rochon ER, Wright DS, Schubert MM, Roman BL. Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations. Cardiovasc Res. 2015 Jul 1;107(1):143-52. doi: 10.1093/cvr/cvv148. Epub 2015 May 12. |
GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development
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Citation:
J Neurochem. 2015;[Epub ahead of print] doi:10.1111/jnc.13259 Epub:
Yes Abstract:
Metabotropic GABAB receptors are known to modulate the activity of voltage-dependent calcium channels. Previously, we have... Citation Extract: Karls A, Mynlieff M. GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development. J Neurochem. 2015;[Epub ahead of print] doi:10.1111/jnc.13259. |
CyclinD1 Down Regulation and Increased Apoptosis Are Common Features of Cohesinopathies.
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Citation:
J Cell Physiol. 2015 Jul 23. doi: 10.1002/jcp.25106. [Epub ahead of print] Epub:
Yes Abstract:
Genetic variants within components of the cohesin complex (NIPBL, SMC1A, SMC3, RAD21, PDS5, ESCO2, HDAC8) are believed to be... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fazio G, Gaston-Massuet C, Bettini LR, Graziola F, Scagliotti V, Cereda A, Ferrari L, Mazzola M, Cazzaniga G, Giordano A, Cotelli F, Bellipanni G, Biondi A, Selicorni A, Pistocchi A, Massa V. CyclinD1 Down Regulation and Increased Apoptosis Are Common Features of Cohesinopathies.. J Cell Physiol. 2015 Jul 23. doi: 10.1002/jcp.25106. [Epub ahead of print]. |
Amphipathic trans-acting phosphorothioate DNA elements mediate the delivery of uncharged nucleic acid sequences in mammalian cells
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Citation:
RSC Adv. 2015;[Epub ahead of print] soi:10.1039/C5RA12038A Epub:
Yes Abstract:
A convenient approach to the delivery of uncharged peptide nucleic acids (PNA) or phosphorodiamidate morpholino (PMO) oligomers... Delivery Method:
dTdaPS hybridization Organism or Cell Type:
cell culture: HeLa pLuc705 Citation Extract: Jain HV, Verthelyi D, Beaucage SL. Amphipathic trans-acting phosphorothioate DNA elements mediate the delivery of uncharged nucleic acid sequences in mammalian cells. RSC Adv. 2015;[Epub ahead of print] soi:10.1039/C5RA12038A . |