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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
Genetic compensation induced by deleterious mutations but not gene knockdowns
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Citation:
Nature. 2015 Aug 13;524(7564):230-3. doi: 10.1038/nature14580. Epub 2015 Jul 13 Epub:
Yes Abstract:
Cells sense their environment and adapt to it by fine-tuning their transcriptome. Wired into this network of gene expression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rossi A, Kontarakis Z, Gerri C, Nolte H, Hölper S, Krüger M, Stainier DYR. Genetic compensation induced by deleterious mutations but not gene knockdowns. Nature. 2015 Aug 13;524(7564):230-3. doi: 10.1038/nature14580. Epub 2015 Jul 13. |
Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish
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Citation:
PLoS ONE. 2015;10(7):e0131908. doi:10.1371/journal.pone.0131908 Epub:
Not Epub Abstract:
Genetic screens are a powerful tool to discover genes that are important in immune cell development and function. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Seiler C, Gebhart N, Zhang Y, Shinton SA, Li Y-s, Ross NL, Liu X, Li Q, Bilbee AN, Varshney GK, LaFave MC, Burgess SM, Balciuniene J, Balciunas D, Hardy RR, Kappes DJ, Wiest DL, Rhodes J. Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. PLoS ONE. 2015;10(7):e0131908. doi:10.1371/journal.pone.0131908. |
Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio
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Citation:
Invert Neurosci. 2015;15:4 doi:10.1007/s10158-015-0180-1 Epub:
Not Epub Abstract:
Oligodendrocytes produce multi-lamellar myelin membranes that surround axons in the central nervous system (CNS). Preservation... Organism or Cell Type:
zebrafish Citation Extract: Morris JF, Chomyk A, Song P, Parker N, Deckard S, Trapp BD, Pimplikar SW, Dutta R. Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio. Invert Neurosci. 2015;15:4 doi:10.1007/s10158-015-0180-1. |
Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32
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Citation:
J Biol Chem. 2015 May 12. pii: jbc.M115.650747. [Epub ahead of print] Epub:
Not Epub Abstract:
Tryptophan was substituted for residues in all four transmembrane domains of connexin32. Function was assayed using dual cell... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM. Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32. J Biol Chem. 2015 May 12. pii: jbc.M115.650747. [Epub ahead of print]. |
Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of R-Smads to Ensure TGFβ-mediated Germ Layer Induction in Xenopus Embryos
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Citation:
J Biol Chem. 2015 May 26. pii: jbc.M115.655605. [Epub ahead of print] Epub:
Yes Abstract:
Germ layer induction is one of the earliest events shortly after fertilization that initiates body formation of vertebrate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Sun G, Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X, Chen YG, Zhang MQ, Tao Q, Wu W. Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of R-Smads to Ensure TGFβ-mediated Germ Layer Induction in Xenopus Embryos. J Biol Chem. 2015 May 26. pii: jbc.M115.655605. [Epub ahead of print]. |
Highly sensitive detection of sequence-specific DNA with morpholino-functionalized magnetic microspheres
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Citation:
Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C5AY00628G Epub:
Yes Abstract:
In this work, a highly effective biosensor supported on morpholino-functionalized magnetic microspheres was investigated for... Citation Extract: Hu W, Ning Y, Li L, Kong J, Zhang X. Highly sensitive detection of sequence-specific DNA with morpholino-functionalized magnetic microspheres. Anal Methods. 2015;[Epub ahead of print] doi:10.1039/C5AY00628G. |
Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment
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Citation:
Cell Host & Microbe. 2015;18(1):15-26. doi:10.1016/j.chom.2015.06.008 Epub:
Not Epub Abstract:
The mycobacterial ESX-1 virulence locus accelerates macrophage recruitment to the forming tuberculous granuloma. Newly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pagán AJ, Chao-Tsung YangC-T, Cameron J, Swaim LE, Ellett F, Lieschke GJ, Ramakrishnan L. Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment. Cell Host & Microbe. 2015;18(1):15-26. doi:10.1016/j.chom.2015.06.008. |
Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential
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Citation:
Sci Rep. 2015;5:11947 doi:10.1038/srep11947 Epub:
Not Epub Abstract:
Malaria parasites alter mosquito feeding behaviour in a way that enhances parasite transmission. This is widely considered a... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Anopheles stephensi (mosquito) Citation Extract: Cator LJ, Pietri JE, Murdock CC, Ohm JR, Lewis EE, Read AF, Luckhart S, Thomas MB. Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential. Sci Rep. 2015;5:11947 doi:10.1038/srep11947. |
Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome
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Citation:
Biochem Cell Biol. 2015 May 25:1-9. [Epub ahead of print] Epub:
Not Epub Abstract:
The polo-like kinases are a family of conserved serine/threonine kinases that play multiple roles in regulation of the cell... Organism or Cell Type:
Xenopus laevis Citation Extract: Rapchak CE, Patel N, Hudson J, Crawford M. Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome. Biochem Cell Biol. 2015 May 25:1-9. [Epub ahead of print]. |
A conserved role of αA-crystallin in the development of the zebrafish embryonic lens
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Citation:
Exp Eye Res. 2015 Jul 3. pii: S0014-4835(15)00220-1. doi: 10.1016/j.exer.2015.07.001. [Epub ahead of print] Epub:
Yes Abstract:
αA- and αB-crystallins are small heat shock proteins that bind thermodynamically destabilized proteins thereby inhibiting their... Organism or Cell Type:
zebrafish Citation Extract: Zou P, Wu SY, Koteiche HA, Mishra S, Levic DS, Knapik E, Chen W, Mchaourab HS. A conserved role of αA-crystallin in the development of the zebrafish embryonic lens. Exp Eye Res. 2015 Jul 3. pii: S0014-4835(15)00220-1. doi: 10.1016/j.exer.2015.07.001. [Epub ahead of print]. |