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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Agents Which Inhibit NF-κB Signaling Block Spontaneous Contractile Activity and Negatively Influence Survival of Developing Myotubes

Authors:
Carlson CG, Stein L, Dole E, Potter RM, Bayless D
Citation:
J Cell Physiol. 2015 Jun 30. doi: 10.1002/jcp.25085. [Epub ahead of print]
Epub:
Yes
Abstract:
Inhibiting the NF-κB signaling pathway provides morphological and functional benefits for the mdx mouse, a model for Duchenne...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: murine primary myotubes
Citation Extract:
Carlson CG, Stein L, Dole E, Potter RM, Bayless D. Agents Which Inhibit NF-κB Signaling Block Spontaneous Contractile Activity and Negatively Influence Survival of Developing Myotubes. J Cell Physiol. 2015 Jun 30. doi: 10.1002/jcp.25085. [Epub ahead of print].

The wound inflammatory response exacerbates growth of pre‐neoplastic cells and progression to cancer

Authors:
Antonio N, Bønnelykke‐Behrndtz ML, Ward LC, Collin J, Christensen IJ, Steiniche T, Schmidt H, Feng Y, Martin P
Citation:
EMBO J. 2015;[Epub ahead of print] doi:10.15252/embj.201490147
Epub:
Yes
Abstract:
There is a long‐standing association between wound healing and cancer, with cancer often described as a “wound that does not...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Antonio N, Bønnelykke‐Behrndtz ML, Ward LC, Collin J, Christensen IJ, Steiniche T, Schmidt H, Feng Y, Martin P. The wound inflammatory response exacerbates growth of pre‐neoplastic cells and progression to cancer. EMBO J. 2015;[Epub ahead of print] doi:10.15252/embj.201490147.

Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches

Authors:
Nizzardo M, Simone C, Dametti S, Salani S, Ulzi G, Pagliarani S, Rizzo F, Frattini E, Pagani F, Bresolin N, Comi G, Corti S
Citation:
Sci Rep. 2015 Jun 30;5:11746. doi: 10.1038/srep11746
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is a primary genetic cause of infant mortality due to mutations in the Survival Motor Neuron (SMN...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: motor neurons and induced pluripotent stam cells (iPSC)
Citation Extract:
Nizzardo M, Simone C, Dametti S, Salani S, Ulzi G, Pagliarani S, Rizzo F, Frattini E, Pagani F, Bresolin N, Comi G, Corti S. Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches. Sci Rep. 2015 Jun 30;5:11746. doi: 10.1038/srep11746.

Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front

Authors:
McLennan R, Schumacher LJ, Morrison JA, Teddy JM, Ridenour DA, Box AC, Semerad CL, Li H, McDowell W, Kay D, Maini PK, Baker RE, Kulesa PM
Citation:
Development. 2015 Jun 1;142(11):2014-25. doi: 10.1242/dev.117507. Epub 2015 May 14
Epub:
Not Epub
Abstract:
Neural crest (NC) cell migration is crucial to the formation of peripheral tissues during vertebrate development. However, how...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, Schumacher LJ, Morrison JA, Teddy JM, Ridenour DA, Box AC, Semerad CL, Li H, McDowell W, Kay D, Maini PK, Baker RE, Kulesa PM. Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front. Development. 2015 Jun 1;142(11):2014-25. doi: 10.1242/dev.117507. Epub 2015 May 14.

BMP signalling controls the construction of vertebrate mucociliary epithelia

Authors:
Cibois M, Luxardi G, Chevalier B, Thomé V, Mercey O, Zaragosi LE, Barbry P, Pasini A, Marcet B, Kodjabachian L
Citation:
Development. 2015 Jun 19. pii: dev.118679. [Epub ahead of print]
Epub:
Yes
Abstract:
Despite the importance of mucociliary epithelia in animal physiology, the mechanisms controlling their establishment are poorly...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cibois M, Luxardi G, Chevalier B, Thomé V, Mercey O, Zaragosi LE, Barbry P, Pasini A, Marcet B, Kodjabachian L. BMP signalling controls the construction of vertebrate mucociliary epithelia. Development. 2015 Jun 19. pii: dev.118679. [Epub ahead of print].

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells

Authors:
Breznau EB, Semack AC, Higashi T, Miller AL
Citation:
Mol Biol Cell. 2015;26:13 2439-2455. doi:10.1091/mbc.E14-11-1553
Epub:
Not Epub
Abstract:
Localized activation of Rho GTPases is essential for multiple cellular functions, including cytokinesis and formation and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Breznau EB, Semack AC, Higashi T, Miller AL. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells. Mol Biol Cell. 2015;26:13 2439-2455. doi:10.1091/mbc.E14-11-1553.

The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish

Authors:
Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C
Citation:
PLoS ONE. 2015;10(6):e0131768. doi:10.1371/journal.pone.0131768
Epub:
Not Epub
Abstract:
During vertebrate neurulation, cranial neural crest cells (CNCCs) undergo epithelial to mesenchymal transition (EMT),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willems B, Tao S, Yu T, Huysseune A, Witten PE, Winkler C. The Wnt Co-Receptor Lrp5 Is Required for Cranial Neural Crest Cell Migration in Zebrafish. PLoS ONE. 2015;10(6):e0131768. doi:10.1371/journal.pone.0131768.

A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation

Authors:
Gil Jang D, Jung Sim H, Kyung Song E, Medina-Ruiz S, Kon Seo J, Joo Park T
Citation:
Dev Biol. 2015 Jun 24. pii: S0012-1606(15)30012-9. doi: 10.1016/j.ydbio.2015.06.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The sh3bgr (SH3 domain binding glutamate-rich) gene encodes a small protein containing a thioredoxin-like fold, SH3 binding...
Organism or Cell Type:
Xenopus
Citation Extract:
Gil Jang D, Jung Sim H, Kyung Song E, Medina-Ruiz S, Kon Seo J, Joo Park T. A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation. Dev Biol. 2015 Jun 24. pii: S0012-1606(15)30012-9. doi: 10.1016/j.ydbio.2015.06.005. [Epub ahead of print].

FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP

Authors:
Yu Y, Reed R
Citation:
PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1506282112
Epub:
Not Epub
Abstract:
The protein fused-in-sarcoma (FUS) is mutated to cause the neurodegenerative disease amyotrophic lateral sclerosis, but its...
Organism or Cell Type:
in vitro transcription-splicing system
Citation Extract:
Yu Y, Reed R. FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP. PNAS. 2015;[Epub ahead of print] doi:10.1073/pnas.1506282112.

Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling

Authors:
Toruń A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M
Citation:
PLoS One. 2015 Jun 25;10(6):e0130818. doi: 10.1371/journal.pone.0130818. eCollection 2015
Epub:
Not Epub
Abstract:
Many adaptor proteins involved in endocytic cargo transport exhibit additional functions in other cellular processes which may...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toruń A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M. Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling. PLoS One. 2015 Jun 25;10(6):e0130818. doi: 10.1371/journal.pone.0130818. eCollection 2015.

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