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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
There are 12143 scientific papers returned from the database with the search filters currently being used below.
E2F8 as a Novel Therapeutic Target for Lung Cancer
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Citation:
J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv151. doi: 10.1093/jnci/djv151. Print 2015 Sep Epub:
Not Epub Abstract:
BACKGROUND: The E2F members have been divided into transcription activators (E2F1-E2F3) and repressors (E2F4-E2F8). E2F8 with... Organism or Cell Type:
cell culture: human lung cancer (LC) cells, xenograft models Vivo-Morpholino Citation Extract: Park SA, Platt J, Lee JW, López-Giráldez F, Herbst RS, Koo JS. E2F8 as a Novel Therapeutic Target for Lung Cancer. J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv151. doi: 10.1093/jnci/djv151. Print 2015 Sep. |
The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development
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Citation:
Hum Mol Genet. 2015 Jun 18. pii: ddv213. [Epub ahead of print] Epub:
Yes Abstract:
DDX11 was recently identified as a cause of Warsaw breakage syndrome (WABS). However, the functional mechanism of DDX11 and the... Organism or Cell Type:
zebrafish Citation Extract: Sun X, Chen H, Deng Z, Hu B, Luo H, Zeng X, Han L, Cai G, Ma L. The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development. Hum Mol Genet. 2015 Jun 18. pii: ddv213. [Epub ahead of print]. |
A Phase I/IIa Clinical Trial in Duchenne Muscular Dystrophy Using Systemically Delivered Morpholino Antisense Oligomer to Skip Exon 53 (SKIP-NMD)
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Citation:
Human Gene Therapy Clinical Development. June 2015, 26(2): 92-95. doi:10.1089/humc.2015.2528 Epub:
Not Epub Organism or Cell Type:
cell culture, tox models, humans Citation Extract: No Authors Listed. A Phase I/IIa Clinical Trial in Duchenne Muscular Dystrophy Using Systemically Delivered Morpholino Antisense Oligomer to Skip Exon 53 (SKIP-NMD). Human Gene Therapy Clinical Development. June 2015, 26(2): 92-95. doi:10.1089/humc.2015.2528. |
Biological Roles of Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1), HSD11B2, and Glucocorticoid Receptor (NR3C1) in Sheep Conceptus Elongation
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Citation:
Biol Reprod. 2015 Jun 17. pii: biolreprod.115.130757. [Epub ahead of print] Epub:
Yes Abstract:
In sheep, the elongating conceptus synthesizes and secretes interferon tau (IFNT), as well as prostaglandins (PGs) and cortisol... Delivery Method:
Endo-Porter Organism or Cell Type:
Ovis aries (sheep) Citation Extract: Brooks K, Burns G, Spencer TE. Biological Roles of Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1), HSD11B2, and Glucocorticoid Receptor (NR3C1) in Sheep Conceptus Elongation. Biol Reprod. 2015 Jun 17. pii: biolreprod.115.130757. [Epub ahead of print]. |
Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line
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Citation:
PLoS ONE. 2015;10(6):e0128944. doi:10.1371/journal.pone.0128944 Epub:
Not Epub Abstract:
Dystrophin (Dmd) is a structural protein that links the extracellular matrix to actin filaments in muscle fibers and is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ruf-Zamojski F, Trivedi V, Fraser SE, Trinh LA. Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line. PLoS ONE. 2015;10(6):e0128944. doi:10.1371/journal.pone.0128944. |
RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis
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Citation:
Cell Cycle. 2015 Jun 17:0. [Epub ahead of print] Epub:
Yes Abstract:
Formin-like 1 (FMNL1) is a member of Formin family proteins which are the actin nucleators. Although FMNL1 activities have been... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Wang F, Zhang L, Duan X, Zhang GL, Wang ZB, Wang Q, Xiong B, Sun SC. RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis. Cell Cycle. 2015 Jun 17:0. [Epub ahead of print]. |
A Macrophage Subversion Factor Is Shared by Intracellular and Extracellular Pathogens
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Citation:
PLoS Pathog. 2015 Jun 16;11(6):e1004969. doi: 10.1371/journal.ppat.1004969. eCollection 2015 Jun Epub:
Not Epub Abstract:
Pathogenic bacteria have developed strategies to adapt to host environment and resist host immune response. Several... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Belon C, Soscia C, Bernut A, Laubier A, Bleves S, Blanc-Potard AB. A Macrophage Subversion Factor Is Shared by Intracellular and Extracellular Pathogens. PLoS Pathog. 2015 Jun 16;11(6):e1004969. doi: 10.1371/journal.ppat.1004969. eCollection 2015 Jun. |
Matrix metalloproteinase 9 modulates collagen matrices and wound repair
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Citation:
Development. 2015 May 26. pii: dev.121160. [Epub ahead of print] Epub:
Yes Abstract:
Acute and chronic injuries are characterized by leukocyte infiltration into tissues. Although matrix metalloproteinase 9 (Mmp9... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: LeBert DC, Squirrell JM, Rindy J, Broadbridge E, Lui Y, Zakrzewska A, Eliceiri KW, Meijer AH, Huttenlocher A. Matrix metalloproteinase 9 modulates collagen matrices and wound repair. Development. 2015 May 26. pii: dev.121160. [Epub ahead of print]. |
Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice
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Citation:
Mol Ther. 2015;[Epub ahead of print] doi:10.1038/mt.2015.88 Epub:
Yes Abstract:
The fatal X-linked Duchenne muscular dystrophy (DMD), characterized by progressive muscle wasting and muscle weakness, is... Delivery Method:
peptide-linked Organism or Cell Type:
mice, mdx Citation Extract: Lu-Nguyen NB, Jarmin SA, Saleh AF, Popplewell L, Gait MJ, Dickson G. Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice. Mol Ther. 2015;[Epub ahead of print] doi:10.1038/mt.2015.88. |
Planar polarization of Vangl2 in the vertebrate neural plate is controlled by Wnt and Myosin II signaling
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Citation:
Biol Open. 2015 Apr 24. pii: bio.011676. doi: 10.1242/bio.201511676. [Epub ahead of print] Epub:
Not Epub Abstract:
The vertebrate neural tube forms as a result of complex morphogenetic movements, which require the functions of several core... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ossipova O, Kim K, Sokol SY. Planar polarization of Vangl2 in the vertebrate neural plate is controlled by Wnt and Myosin II signaling. Biol Open. 2015 Apr 24. pii: bio.011676. doi: 10.1242/bio.201511676. [Epub ahead of print]. |