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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

Authors:
Liu Y, Chen X, Qin B, Zhao K, Zhao Q, Staley JP, Zhao C
Citation:
J Ophthalmol. 2015;(2015):816329 doi:10.1155/2015/816329
Epub:
Not Epub
Abstract:
Purpose. The small nuclear ribonucleoprotein 200 kDa (SNRNP200) gene is a fundamental component for precursor message RNA (pre-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Chen X, Qin B, Zhao K, Zhao Q, Staley JP, Zhao C. Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish. J Ophthalmol. 2015;(2015):816329 doi:10.1155/2015/816329.

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells

Authors:
Wu L, Wary KK, Revskoy S, Gao X, Tsang K, Komarova YA, Rehman J, Malik AB
Citation:
Stem Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.stemcr.2015.05.016
Epub:
Yes
Abstract:
Understanding epigenetic mechanisms regulating embryonic stem cell (ESC) differentiation to endothelial cells may lead to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu L, Wary KK, Revskoy S, Gao X, Tsang K, Komarova YA, Rehman J, Malik AB. Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells. Stem Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.stemcr.2015.05.016.

Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging

Authors:
Fujisawa K, Terai S, Matsumoto T, Takami T, Yamamoto N, Nishina H, Furutani-Seiki M, Sakaida I
Citation:
PLoS ONE. 2015;10(6): e0129950. doi:10.1371/journal.pone.0129950
Epub:
Not Epub
Abstract:
Maid is a helix-loop-helix protein that is involved in cell proliferation. In order to further elucidate its physiological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fujisawa K, Terai S, Matsumoto T, Takami T, Yamamoto N, Nishina H, Furutani-Seiki M, Sakaida I. Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging. PLoS ONE. 2015;10(6): e0129950. doi:10.1371/journal.pone.0129950.

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism

Authors:
Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M
Citation:
Sci Rep. 2015;5:11603. doi:10.1038/srep11603
Epub:
Not Epub
Abstract:
. . Insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) signalling is required for normal embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis and Xenopus tropicalis
Citation Extract:
Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M. Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism. Sci Rep. 2015;5:11603. doi:10.1038/srep11603.

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

Authors:
Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJA
Citation:
Sci Rep. 2015;5:11632. doi:10.1038/srep11632
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by absence of the integral structural protein, dystrophin, which renders muscle...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice, mdx
Citation Extract:
Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJA. Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy. Sci Rep. 2015;5:11632. doi:10.1038/srep11632.

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis

Authors:
Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC
Citation:
PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015
Epub:
Not Epub
Abstract:
Skin disorders are widespread, but available treatments are limited. A more comprehensive understanding of skin development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC. Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015.

Expression change in Angiopoietin-1 underlies change in relative brain size in fish

Authors:
Chen Y-C, Harrison PW, Kotrschal A, Kolm N, Mank JE, Panula P
Citation:
Proc. R. Soc. B. 2015;282 20150872; DOI: 10.1098/rspb.2015.0872
Epub:
Yes
Abstract:
Brain size varies substantially across the animal kingdom and is often associated with cognitive ability; however, the genetic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Y-C, Harrison PW, Kotrschal A, Kolm N, Mank JE, Panula P. Expression change in Angiopoietin-1 underlies change in relative brain size in fish. Proc. R. Soc. B. 2015;282 20150872; DOI: 10.1098/rspb.2015.0872.

Hsp47 mediates Cx43-dependent skeletal growth and patterning in the regenerating fin

Authors:
Bhadra J, Iovine MK
Citation:
Mech Dev. 2015 Jun 20. pii: S0925-4773(15)00048-9. doi: 10.1016/j.mod.2015.06.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal morphogenesis describes how bones achieve their correct shape and size and appropriately position joints. We use the...
Organism or Cell Type:
zebrafish
Citation Extract:
Bhadra J, Iovine MK. Hsp47 mediates Cx43-dependent skeletal growth and patterning in the regenerating fin. Mech Dev. 2015 Jun 20. pii: S0925-4773(15)00048-9. doi: 10.1016/j.mod.2015.06.004. [Epub ahead of print].

Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Authors:
Dubrulle J, Jordan BM, Akhmetova L, Farrell JA, Kim SH, Solnica-Krezel L, Schier AF
Citation:
Elife. 2015 Apr 14;4. doi: 10.7554/eLife.05042
Epub:
Not Epub
Abstract:
Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dubrulle J, Jordan BM, Akhmetova L, Farrell JA, Kim SH, Solnica-Krezel L, Schier AF. Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. Elife. 2015 Apr 14;4. doi: 10.7554/eLife.05042.

MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma

Authors:
Conte I, Hadfield KD, Barbato S, Carrella S, Pizzo M, Bhat RS, Carissimo A, Karali M, Porter LF, Urquhart J, Hateley S, O'Sullivan J, Manson FD, Neuhauss SC, Banfi S, Black GC
Citation:
Proc Natl Acad Sci U S A. 2015 Jun 8. pii: 201401464. [Epub ahead of print]
Epub:
Yes
Abstract:
Ocular developmental disorders, including the group classified as microphthalmia, anophthalmia, and coloboma (MAC) and...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Conte I, Hadfield KD, Barbato S, Carrella S, Pizzo M, Bhat RS, Carissimo A, Karali M, Porter LF, Urquhart J, Hateley S, O'Sullivan J, Manson FD, Neuhauss SC, Banfi S, Black GC. MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma. Proc Natl Acad Sci U S A. 2015 Jun 8. pii: 201401464. [Epub ahead of print].

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