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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Expression and Misexpression of the miR-183 Family in the Developing Hearing Organ of the Chicken

Authors:
Zhang KD, Stoller ML, Fekete DM
Citation:
PLoS ONE. 2015;10(7):e0132796. doi:10.1371/journal.pone.0132796
Epub:
Not Epub
Abstract:
The miR-183 family consists of 3 related microRNAs (miR-183, miR-96, miR-182) that are required to complete maturation of...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Zhang KD, Stoller ML, Fekete DM. Expression and Misexpression of the miR-183 Family in the Developing Hearing Organ of the Chicken. PLoS ONE. 2015;10(7):e0132796. doi:10.1371/journal.pone.0132796.

Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides

Authors:
Burki U, Keane J, Blain A, O'Donovan L, Gait MJ, Laval SH, Straub V
Citation:
Nucleic Acid Ther. 2015 Jul 15. [Epub ahead of print]
Epub:
Yes
Abstract:
Antisense oligonucleotide (AON)-induced exon skipping is one of the most promising strategies for treating Duchenne muscular...
Delivery Method:
peptide-linked
Citation Extract:
Burki U, Keane J, Blain A, O'Donovan L, Gait MJ, Laval SH, Straub V. Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides. Nucleic Acid Ther. 2015 Jul 15. [Epub ahead of print].

Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish

Authors:
Kamaid A, Molina-Villa T, Mendoza V, Pujades C, Maldonado E, Ispizua Belmonte JC, López-Casillas F
Citation:
Genesis. 2015 Jul 15. doi: 10.1002/dvg.22876. [Epub ahead of print]
Epub:
Yes
Abstract:
Angiogenesis is an essential requirement for embryonic development and adult homeostasis. Its deregulation is a key feature of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kamaid A, Molina-Villa T, Mendoza V, Pujades C, Maldonado E, Ispizua Belmonte JC, López-Casillas F. Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish. Genesis. 2015 Jul 15. doi: 10.1002/dvg.22876. [Epub ahead of print].

Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae

Authors:
Wang H, Semenova S, Kuusela S, Panula P, Lehtonen S
Citation:
FASEB J. 2015 Jul 13. pii: fj.15-271817. [Epub ahead of print]
Epub:
Yes
Abstract:
The central melanocortin system is a key regulator of energy homeostasis. Recent studies indicate that tankyrases (TNKSs),...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang H, Semenova S, Kuusela S, Panula P, Lehtonen S. Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae. FASEB J. 2015 Jul 13. pii: fj.15-271817. [Epub ahead of print].

Mutations within the LINC-HELLP noncoding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation

Authors:
van Dijk M, Visser A, Buabeng KML, Poutsma A, van der Schors RC, Oudejans CBM
Citation:
Hum Mol Genet. 2015;[Epub ahead of print] doi:10.1093/hmg/ddv274
Epub:
Yes
Abstract:
LINC-HELLP, showing chromosomal linkage with the pregnancy-specific HELLP-syndrome in Dutch families, reduces differentiation...
Citation Extract:
van Dijk M, Visser A, Buabeng KML, Poutsma A, van der Schors RC, Oudejans CBM. Mutations within the LINC-HELLP noncoding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation. Hum Mol Genet. 2015;[Epub ahead of print] doi:10.1093/hmg/ddv274.

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

Authors:
Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SA, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, UK10K Consortium, University of Washington Center for Mendelian Genomics, <database limit - authors omitted> Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA
Citation:
Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201
Epub:
Yes
Abstract:
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SA, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, UK10K Consortium, University of Washington Center for Mendelian Genomics, <database limit - authors omitted> Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201.

Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model

Authors:
Chen X, Wang J, Cao Z, Hosaka K, Jensen L, Yang H, Sun Y, Zhuang R, Liu Y, Cao Y
Citation:
Sci Rep. 2015;5:10351. doi:10.1038/srep10351
Epub:
Not Epub
Abstract:
Retinoblastoma is a highly invasive malignant tumor that often invades the brain and metastasizes to distal organs through the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Wang J, Cao Z, Hosaka K, Jensen L, Yang H, Sun Y, Zhuang R, Liu Y, Cao Y. Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model. Sci Rep. 2015;5:10351. doi:10.1038/srep10351.

Identification of Polycystin-2 and CFTR common targets

Authors:
Roxo-Rosa M, Lopes SS
Citation:
Cilia. 2015;4(Suppl 1):P4 doi:10.1186/2046-2530-4-S1-P4
Epub:
Not Epub
Abstract:
Poster From Cilia 2014
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roxo-Rosa M, Lopes SS. Identification of Polycystin-2 and CFTR common targets. Cilia. 2015;4(Suppl 1):P4 doi:10.1186/2046-2530-4-S1-P4.

Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder

Authors:
Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV, Tao F, Speziani F, Abreu L, Schüle R, Caporali L, La Morgia C, Maresca A, Liguori R, Lodi R, Ahmed ZM, Sund KL, Wang X, Krueger LA, Peng Y, Prada CE, Prows CA, Schorry EK, Antonellis A, Zimmerman HH, Abdul-Rahman OA, Yang Y, Downes SM, Prince J, Fontanesi F, Barrientos A, Németh AH, Carelli V, Huang T, Zuchner S, Dallman JE
Citation:
Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3354
Epub:
Yes
Abstract:
Dominant optic atrophy (DOA) and axonal peripheral neuropathy (Charcot-Marie-Tooth type 2, or CMT2) are hereditary...
Organism or Cell Type:
zebrafish
Citation Extract:
Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV, Tao F, Speziani F, Abreu L, Schüle R, Caporali L, La Morgia C, Maresca A, Liguori R, Lodi R, Ahmed ZM, Sund KL, Wang X, Krueger LA, Peng Y, Prada CE, Prows CA, Schorry EK, Antonellis A, Zimmerman HH, Abdul-Rahman OA, Yang Y, Downes SM, Prince J, Fontanesi F, Barrientos A, Németh AH, Carelli V, Huang T, Zuchner S, Dallman JE. Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nat Genet. 2015;[Epub ahead of print] doi:10.1038/ng.3354.

The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier

Authors:
Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J
Citation:
Kidney Int. 2015 Jul 8. doi: 10.1038/ki.2015.197. [Epub ahead of print]
Epub:
Yes
Abstract:
Podocyte dysfunction impairs the size selectivity of the glomerular filter, leading to proteinuria, hypoalbuminuria, and edema...
Organism or Cell Type:
zebrafish
Citation Extract:
Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J. The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney Int. 2015 Jul 8. doi: 10.1038/ki.2015.197. [Epub ahead of print].

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