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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν; (POLN)

Authors:
Takata KI, Tomida J, Reh S, Swanhart LM, Takata M, Hukriede NA, Wood RD
Citation:
J Biol Chem. 2015 Aug 12. pii: jbc.M115.677419. [Epub ahead of print]
Epub:
Yes
Abstract:
DNA polymerase ν (POLN) is one of 16 DNA polymerases encoded in vertebrate genomes. It is important to determine its gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takata KI, Tomida J, Reh S, Swanhart LM, Takata M, Hukriede NA, Wood RD. Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν; (POLN). J Biol Chem. 2015 Aug 12. pii: jbc.M115.677419. [Epub ahead of print].

Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application

Authors:
Salewsky B, Hildebrand G, Rothe S, Parplys AC, Radszewski J, Kieslich M, Wessendorf P, Krenzlin H, Borgmann K, Nussenzweig A, Sperling K, Digweed M
Citation:
Mol Ther. 2016 Feb;24(1):117-24. doi: 10.1038/mt.2015.144. Epub 2015 Aug 12.
Epub:
Yes
Abstract:
Over 90% of patients with Nijmegen breakage syndrome (NBS), a hereditary cancer disorder, are homoallelic for a 5bp deletion in...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Salewsky B, Hildebrand G, Rothe S, Parplys AC, Radszewski J, Kieslich M, Wessendorf P, Krenzlin H, Borgmann K, Nussenzweig A, Sperling K, Digweed M. Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application. Mol Ther. 2016 Feb;24(1):117-24. doi: 10.1038/mt.2015.144. Epub 2015 Aug 12..

Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis

Authors:
Agricola ZN, Jagpal AK, Allbee AW, Prewitt AR, Shifley ET, Rankin SA, Zorn AM, Kenny AP
Citation:
Dev Dyn. 2015 Aug 12. doi: 10.1002/dvdy.24314. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: During primitive hematopoiesis in Xenopus, cebpa and spib expressing myeloid cells emerge from the anterior ventral...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Agricola ZN, Jagpal AK, Allbee AW, Prewitt AR, Shifley ET, Rankin SA, Zorn AM, Kenny AP. Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis. Dev Dyn. 2015 Aug 12. doi: 10.1002/dvdy.24314. [Epub ahead of print].

Mutations in DCHS1 cause mitral valve prolapse

Authors:
Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA
Citation:
Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10
Epub:
Not Epub
Abstract:
Mitral valve prolapse (MVP) is a common cardiac valve disease that affects nearly 1 in 40 individuals. It can manifest as...
Organism or Cell Type:
zebrafish
Citation Extract:
Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA. Mutations in DCHS1 cause mitral valve prolapse. Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10.

The N-terminal acetyltransferase Naa10 is essential for zebrafish development

Authors:
Ree RM, Myklebust LM, Thiel P, Foyn H, Fladmark KE, Arnesen T
Citation:
Biosci Rep. 2015 Aug 6. pii: BSR20150168. [Epub ahead of print]
Epub:
Yes
Abstract:
N-terminal acetylation, catalyzed by N-terminal acetyltransferases (NATs), is among the most common protein modifications in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ree RM, Myklebust LM, Thiel P, Foyn H, Fladmark KE, Arnesen T. The N-terminal acetyltransferase Naa10 is essential for zebrafish development. Biosci Rep. 2015 Aug 6. pii: BSR20150168. [Epub ahead of print].

Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

Authors:
Chew TS, O'Shea NR, Sewell GW, Oehlers SH, Mulvey CM, Crosier PS, Godovac-Zimmermann J, Bloom SL, Smith AM, Segal AW
Citation:
Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4
Epub:
Not Epub
Abstract:
Crohn's disease (CD) is associated with delayed neutrophil recruitment and bacterial clearance at sites of acute...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chew TS, O'Shea NR, Sewell GW, Oehlers SH, Mulvey CM, Crosier PS, Godovac-Zimmermann J, Bloom SL, Smith AM, Segal AW. Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis. Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4.

Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces

Authors:
Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R
Citation:
Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30
Epub:
Not Epub
Abstract:
Contact inhibition of locomotion (CIL) is the process through which cells move away from each other after cell-cell contact,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R. Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces. Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30.

Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution

Authors:
Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW
Citation:
BMC Biol. 2015 Aug 1;13:56. doi: 10.1186/s12915-015-0165-x
Epub:
Not Epub
Abstract:
BACKGROUND: The functional consequences of whole genome duplications in vertebrate evolution are not fully understood. It...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Marlétaz F, Maeso I, Faas L, Isaacs HV, Holland PW. Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution. BMC Biol. 2015 Aug 1;13:56. doi: 10.1186/s12915-015-0165-x.

Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

Authors:
Percival SM, Thomas HR, Amsterdam A, Carroll AJ, Lees JA, Yost HJ, Parant JM
Citation:
Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4
Epub:
Not Epub
Abstract:
Mutations in ESCO2, one of two establishment of cohesion factors necessary for proper sister chromatid cohesion (SCC), cause a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Percival SM, Thomas HR, Amsterdam A, Carroll AJ, Lees JA, Yost HJ, Parant JM. Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome. Dis Model Mech. 2015 Aug 1;8(8):941-55. doi: 10.1242/dmm.019059. Epub 2015 Jun 4.

Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos

Authors:
Hu Z, Holzschuh J, Driever W
Citation:
PLoS One. 2015 Jul 30;10(7):e0134299. doi: 10.1371/journal.pone.0134299. eCollection 2015
Epub:
Not Epub
Abstract:
DNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu Z, Holzschuh J, Driever W. Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos. PLoS One. 2015 Jul 30;10(7):e0134299. doi: 10.1371/journal.pone.0134299. eCollection 2015.

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