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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish

Authors:
Hung FC, Shih HY, Cheng YC, Chao C
Citation:
Stem Cells Dev. 2015 Sep 28. [Epub ahead of print]
Epub:
Yes
Abstract:
Growth-arrest-specific 7 (Gas7) is preferentially expressed in the nervous system and plays an important role during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung FC, Shih HY, Cheng YC, Chao C. Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish. Stem Cells Dev. 2015 Sep 28. [Epub ahead of print].

Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome

Authors:
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N
Citation:
Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print]
Epub:
Yes
Abstract:
The nuclear pore complex (NPC) is a huge protein complex embedded in the nuclear envelope. It has central functions in...
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N. Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome. Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print].

Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II

Authors:
Matos L, Gonçalves V, Pinto E, Laranjeira F, Prata MJ, Jordan P, Desviat LR, Pérez B, Alves S
Citation:
Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print]
Epub:
Yes
Abstract:
Mucopolysaccharidosis II is a lysosomal storage disorder caused by mutations in the IDS gene, including exonic alterations...
Organism or Cell Type:
cell culture: human primary cells
Citation Extract:
Matos L, Gonçalves V, Pinto E, Laranjeira F, Prata MJ, Jordan P, Desviat LR, Pérez B, Alves S. Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II. Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print].

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function

Authors:
Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO
Citation:
Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391
Epub:
Not Epub
Abstract:
Membrane proteins are crucial to heart function and development. Here we combine cationic silica-bead coating with shotgun...
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391.

HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish

Authors:
He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H
Citation:
Mol Neurobiol. 2015 Sep 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Histone deacetylases (HDACs) are involved in multiple developmental processes, but their functions in the development of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H. HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish. Mol Neurobiol. 2015 Sep 22. [Epub ahead of print].

Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas

Authors:
Won M, Ro H, Dawid IB
Citation:
Proc Natl Acad Sci U S A. 2015 Sep 21. pii: 201517033. [Epub ahead of print]
Epub:
Yes
Abstract:
The gene encoding the E3 ubiquitin ligase Ligand of Numb protein-X (Lnx)2a is expressed in the ventral-anterior pancreatic bud...
Organism or Cell Type:
zebrafish
Citation Extract:
Won M, Ro H, Dawid IB. Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas. Proc Natl Acad Sci U S A. 2015 Sep 21. pii: 201517033. [Epub ahead of print].

The Role of ARF6 in Biliary Atresia

Authors:
Ningappa M, So J, Glessner J, Ashokkumar C, Ranganathan S, Min J, Higgs BW, Sun Q, Haberman K, Schmitt L, Vilarinho S, Mistry PK, Vockley G, Dhawan A, Gittes GK, Hakonarson H, Jaffe R, Subramaniam S, Shin D, Sindhi R
Citation:
PLoS One. 2015 Sep 17;10(9):e0138381. doi: 10.1371/journal.pone.0138381. eCollection 2015
Epub:
Not Epub
Abstract:
BACKGROUND & AIMS: Altered extrahepatic bile ducts, gut, and cardiovascular anomalies constitute the variable phenotype of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ningappa M, So J, Glessner J, Ashokkumar C, Ranganathan S, Min J, Higgs BW, Sun Q, Haberman K, Schmitt L, Vilarinho S, Mistry PK, Vockley G, Dhawan A, Gittes GK, Hakonarson H, Jaffe R, Subramaniam S, Shin D, Sindhi R. The Role of ARF6 in Biliary Atresia. PLoS One. 2015 Sep 17;10(9):e0138381. doi: 10.1371/journal.pone.0138381. eCollection 2015.

Knockdown of Tmem234 in zebrafish results in proteinuria

Authors:
Rodriguez PQ, Oddsson A, Ebarasi L, He B, Hultenby K, Wernerson A, Betsholtz C, Tryggvason K, Patrakka J
Citation:
Am J Physiol Renal Physiol. 2015 Sep 16:ajprenal.00525.2014. doi: 10.1152/ajprenal.00525.2014. [Epub ahead of print]
Epub:
Yes
Abstract:
Podocytes are highly specialized epithelial cells located at the outer aspects of the glomerular capillary tuft and critical...
Organism or Cell Type:
zebrafish
Citation Extract:
Rodriguez PQ, Oddsson A, Ebarasi L, He B, Hultenby K, Wernerson A, Betsholtz C, Tryggvason K, Patrakka J. Knockdown of Tmem234 in zebrafish results in proteinuria. Am J Physiol Renal Physiol. 2015 Sep 16:ajprenal.00525.2014. doi: 10.1152/ajprenal.00525.2014. [Epub ahead of print].

Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish

Authors:
Liu F, Xia W, Hu J, Wang Y, Yang F, Sun S, Zhang J, Jiang N, Wang H, Tian W, Wang X, Ma D
Citation:
PLoS One. 2015 Sep 16;10(9):e0136832. doi: 10.1371/journal.pone.0136832. eCollection 2015
Epub:
Not Epub
Abstract:
Hearing loss is one of the most prevalent human birth defects. Genetic factors contribute to the pathogenesis of deafness. It...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu F, Xia W, Hu J, Wang Y, Yang F, Sun S, Zhang J, Jiang N, Wang H, Tian W, Wang X, Ma D. Solute Carrier Family 26 Member a2 (slc26a2) Regulates Otic Development and Hair Cell Survival in Zebrafish. PLoS One. 2015 Sep 16;10(9):e0136832. doi: 10.1371/journal.pone.0136832. eCollection 2015.

Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo

Authors:
Zhou Y, Fomovska A, Muench S, Lai BS, Mui E, McLeod R
Citation:
Antimicrob Agents Chemother. 2014;58(3):1789-92. doi: 10.1128/AAC.02225-13. Epub 2013 Dec 23. PMID: 24366743
Epub:
Not Epub
Abstract:
Here, we show that spiroindolone, an effective treatment for plasmodia, is also active against Toxoplasma gondii tachyzoites....
Delivery Method:
peptide-linked
Organism or Cell Type:
Toxoplasma gondii
Citation Extract:
Zhou Y, Fomovska A, Muench S, Lai BS, Mui E, McLeod R. Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo. Antimicrob Agents Chemother. 2014;58(3):1789-92. doi: 10.1128/AAC.02225-13. Epub 2013 Dec 23. PMID: 24366743 .

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