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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

Authors:
Grande MT, Sánchez-Laorden B, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM, Nieto MA
Citation:
Nat Med. 2015 Sep;21(9):989-97. doi: 10.1038/nm.3901. Epub 2015 Aug 3
Epub:
Not Epub
Abstract:
Progressive kidney fibrosis contributes greatly to end-stage renal failure, and no specific treatment is available to preserve...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Grande MT, Sánchez-Laorden B, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM, Nieto MA. Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. Nat Med. 2015 Sep;21(9):989-97. doi: 10.1038/nm.3901. Epub 2015 Aug 3.

Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation

Authors:
Simões-Costa M, Stone M, Bronner ME
Citation:
Dev Cell. 2015 Aug 5. pii: S1534-5807(15)00451-7. doi: 10.1016/j.devcel.2015.06.024. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells are induced at the neural plate border by the combined action of transcription factors and signaling...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Simões-Costa M, Stone M, Bronner ME. Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation. Dev Cell. 2015 Aug 5. pii: S1534-5807(15)00451-7. doi: 10.1016/j.devcel.2015.06.024. [Epub ahead of print].

Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development

Authors:
Swindell EC, Yuan Q, Maili LE, Tandon B, Wagner DS, Hecht JT
Citation:
Genesis. 2015 Aug 22. doi: 10.1002/dvg.22897. [Epub ahead of print]
Epub:
Yes
Abstract:
The CAP superfamily member, CRISPLD2, has previously been shown to be associated with nonsyndromic cleft lip and palate (NSCLP...
Organism or Cell Type:
zebrafish
Citation Extract:
Swindell EC, Yuan Q, Maili LE, Tandon B, Wagner DS, Hecht JT. Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development. Genesis. 2015 Aug 22. doi: 10.1002/dvg.22897. [Epub ahead of print].

Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway

Authors:
Vitorino M, Silva AC, Inácio JM, Ramalho JS, Gur M, Fainsod A, Steinbeisser H, Belo JA
Citation:
PLoS One. 2015 Aug 13;10(8):e0135504. doi: 10.1371/journal.pone.0135504. eCollection 2015
Epub:
Not Epub
Abstract:
Protein Kinase Domain Containing, Cytoplasmic (PKDCC) is a protein kinase which has been implicated in longitudinal bone growth...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vitorino M, Silva AC, Inácio JM, Ramalho JS, Gur M, Fainsod A, Steinbeisser H, Belo JA. Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway. PLoS One. 2015 Aug 13;10(8):e0135504. doi: 10.1371/journal.pone.0135504. eCollection 2015.

The transcriptional coactivator Taz regulates proximodistal patterning of the pronephric tubule in zebrafish

Authors:
Zhang J, Yuan S, Vasilyev A, Amin Arnaout M
Citation:
Mech Dev. 2015 Aug 4. pii: S0925-4773(15)30019-8. doi: 10.1016/j.mod.2015.08.001. [Epub ahead of print]
Epub:
Yes
Abstract:
The zebrafish pronephric tubule consists of proximal and distal segments and a collecting duct. The proximal segment is...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Yuan S, Vasilyev A, Amin Arnaout M. The transcriptional coactivator Taz regulates proximodistal patterning of the pronephric tubule in zebrafish. Mech Dev. 2015 Aug 4. pii: S0925-4773(15)30019-8. doi: 10.1016/j.mod.2015.08.001. [Epub ahead of print].

The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left-right asymmetry in zebrafish

Authors:
Gokey JJ, Dasgupta A, Amack JD
Citation:
Dev Biol. 2015 Aug 5:DBIO1531. doi: 10.1016/j.ydbio.2015.08.002. [Epub ahead of print]
Epub:
Yes
Abstract:
Asymmetric fluid flows generated by motile cilia in a transient 'organ of asymmetry' are involved in establishing the...
Organism or Cell Type:
zebrafish
Citation Extract:
Gokey JJ, Dasgupta A, Amack JD. The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left-right asymmetry in zebrafish. Dev Biol. 2015 Aug 5:DBIO1531. doi: 10.1016/j.ydbio.2015.08.002. [Epub ahead of print].

Sebox regulates mesoderm formation in early amphibian embryos

Authors:
Chen G, Tan RB, Tao QH
Citation:
Dev Dyn. 2015 Aug 18. doi: 10.1002/dvdy.24323. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Mix/Bix genes are important regulators of mesendoderm formation during vertebrate embryogenesis. Sebox, an...
Organism or Cell Type:
Xenopus
Citation Extract:
Chen G, Tan RB, Tao QH. Sebox regulates mesoderm formation in early amphibian embryos. Dev Dyn. 2015 Aug 18. doi: 10.1002/dvdy.24323. [Epub ahead of print].

Neural crest specification by Prohibitin1 depends on transcriptional regulation of prl3 and vangl1

Authors:
Deichmann C, Link M, Seyfang M, Knotz V, Gradl D, Wedlich D
Citation:
Genesis. 2015 Aug 11. doi: 10.1002/dvg.22883. [Epub ahead of print]
Epub:
Yes
Abstract:
A complex network of transcription factors regulates specification of neural crest cells at early neurula stage by stabilizing...
Organism or Cell Type:
Xenopus
Citation Extract:
Deichmann C, Link M, Seyfang M, Knotz V, Gradl D, Wedlich D. Neural crest specification by Prohibitin1 depends on transcriptional regulation of prl3 and vangl1. Genesis. 2015 Aug 11. doi: 10.1002/dvg.22883. [Epub ahead of print].

In vivo assessment of contractile strength distinguishes differential gene function in skeletal muscle of zebrafish larvae

Authors:
Martin BL, Gallagher TL, Rastogi N, Davis JP, Beattie CE, Amacher SL, Janssen PM
Citation:
J Appl Physiol (1985). 2015 Aug 6:jap.00447.2015. doi: 10.1152/japplphysiol.00447.2015. [Epub ahead of print]
Epub:
Yes
Abstract:
The accessible genetics and extensive skeletal musculature of the zebrafish make it a versatile and increasingly used model for...
Organism or Cell Type:
zebrafish
Citation Extract:
Martin BL, Gallagher TL, Rastogi N, Davis JP, Beattie CE, Amacher SL, Janssen PM. In vivo assessment of contractile strength distinguishes differential gene function in skeletal muscle of zebrafish larvae. J Appl Physiol (1985). 2015 Aug 6:jap.00447.2015. doi: 10.1152/japplphysiol.00447.2015. [Epub ahead of print].

NF2/Merlin is required for the axial pattern formation in the Xenopus laevis embryo

Authors:
Zhu X, Min Z, Tan R, Tao Q
Citation:
Mech Dev. 2015 Sep 3. pii: S0925-4773(15)30025-3. doi: 10.1016/j.mod.2015.08.008. [Epub ahead of print]
Epub:
Yes
Abstract:
The NF2 gene product Merlin is a FERM-domain protein possessing a broad tumor-suppressing function. NF2/Merlin has been...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhu X, Min Z, Tan R, Tao Q. NF2/Merlin is required for the axial pattern formation in the Xenopus laevis embryo. Mech Dev. 2015 Sep 3. pii: S0925-4773(15)30025-3. doi: 10.1016/j.mod.2015.08.008. [Epub ahead of print].

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