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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Maternal and Zygotic Sphingosine Kinase 2 are Indispensable for Cardiac Development in Zebrafish

Authors:
Hisano Y, Inoue A, Okudaira M, Taimatsu K, Matsumoto H, Kotani H, Ohga R, Aoki J, Kawahara A
Citation:
J Biol Chem. 2015 Apr 23. pii: jbc.M114.634717. [Epub ahead of print]
Epub:
Yes
Abstract:
Sphingosine 1-phosphate (S1P) is synthesized from sphingosine by sphingosine kinases (SPHK1 and SPHK2) in invertebrates and...
Organism or Cell Type:
zebrafish
Citation Extract:
Hisano Y, Inoue A, Okudaira M, Taimatsu K, Matsumoto H, Kotani H, Ohga R, Aoki J, Kawahara A. Maternal and Zygotic Sphingosine Kinase 2 are Indispensable for Cardiac Development in Zebrafish. J Biol Chem. 2015 Apr 23. pii: jbc.M114.634717. [Epub ahead of print].

Vascular Mural Cells Promote Noradrenergic Differentiation of Embryonic Sympathetic Neurons

Authors:
Fortuna V, Pardanaud L, Brunet I, Ola R, Ristori E, Santoro MM, Nicoli S, Eichmann A
Citation:
Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.05.028
Epub:
Yes
Abstract:
The sympathetic nervous system controls smooth muscle tone and heart rate in the cardiovascular system. Postganglionic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fortuna V, Pardanaud L, Brunet I, Ola R, Ristori E, Santoro MM, Nicoli S, Eichmann A. Vascular Mural Cells Promote Noradrenergic Differentiation of Embryonic Sympathetic Neurons. Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.05.028.

Synthesis of phosphorodiamidate morpholino oligonucleotides by H-phosphonate method

Authors:
Bhadra J, Kundu J, KC Ghosh, Sinha S
Citation:
Tetrahedron Lett. 2015;[Epub ahead of print] doi:10.1016/j.tetlet.2015.05.080
Epub:
Yes
Abstract:
Synthesis of T-containing phosphorodiamidate morpholino oligomers (PMO) by H-phosphonate method on solid support has been...
Citation Extract:
Bhadra J, Kundu J, KC Ghosh, Sinha S. Synthesis of phosphorodiamidate morpholino oligonucleotides by H-phosphonate method. Tetrahedron Lett. 2015;[Epub ahead of print] doi:10.1016/j.tetlet.2015.05.080.

A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish

Authors:
Quach HN, Tao S, Vrljicak P, Joshi A, Ruan H, Sukumaran R, Varshney GK, LaFave MC, Screen Team TD, Burgess SM, Winkler C, Emelyanov A, Parinov S, Sampath K
Citation:
G3 (Bethesda). 2015 Apr 2. pii: g3.114.015842. doi: 10.1534/g3.114.015842. [Epub ahead of print]
Epub:
Yes
Abstract:
Since the sequencing of the human reference genome, many human disease-related genes have been discovered. However,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quach HN, Tao S, Vrljicak P, Joshi A, Ruan H, Sukumaran R, Varshney GK, LaFave MC, Screen Team TD, Burgess SM, Winkler C, Emelyanov A, Parinov S, Sampath K. A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish. G3 (Bethesda). 2015 Apr 2. pii: g3.114.015842. doi: 10.1534/g3.114.015842. [Epub ahead of print].

Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism

Authors:
Manchenkov T, Pasillas MP, Haddad GG, Imam FB
Citation:
G3 (Bethesda). 2015 Apr 3. pii: g3.115.018010. doi: 10.1534/g3.115.018010. [Epub ahead of print]
Epub:
Yes
Abstract:
Severe hypoxia is a common cause of major brain, heart, and kidney injury in adults, children, and newborns. However, mild...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Manchenkov T, Pasillas MP, Haddad GG, Imam FB. Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism. G3 (Bethesda). 2015 Apr 3. pii: g3.115.018010. doi: 10.1534/g3.115.018010. [Epub ahead of print].

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

Authors:
Vanhollebeke B, Stone OA, Bostaille N, Cho C, Zhou Y, Maquet E, Gauquier A, Cabochette P, Fukuhara S, Mochizuki N, Nathans J, Stainier DYR
Citation:
eLife. 2015;4:e06489. doi:10.7554/eLife.06489
Epub:
Not Epub
Abstract:
Despite the critical role of endothelial Wnt/β-catenin signaling during central nervous system (CNS) vascularization, how...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vanhollebeke B, Stone OA, Bostaille N, Cho C, Zhou Y, Maquet E, Gauquier A, Cabochette P, Fukuhara S, Mochizuki N, Nathans J, Stainier DYR. Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. eLife. 2015;4:e06489. doi:10.7554/eLife.06489.

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

Authors:
Killedar A, Stutz MD, Sobinoff AP, Tomlinson CG, Bryan TM, Beesley J, Chenevix-Trench G, Reddel RR, Pickett HA
Citation:
PLoS Genet. 2015 Jun 8;11(6):e1005286. doi: 10.1371/journal.pgen.1005286. eCollection 2015 Jun
Epub:
Not Epub
Abstract:
The TERT-CLPTM1L region of chromosome 5p15.33 is a multi-cancer susceptibility locus that encodes the reverse transcriptase...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293T
Citation Extract:
Killedar A, Stutz MD, Sobinoff AP, Tomlinson CG, Bryan TM, Beesley J, Chenevix-Trench G, Reddel RR, Pickett HA. A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase. PLoS Genet. 2015 Jun 8;11(6):e1005286. doi: 10.1371/journal.pgen.1005286. eCollection 2015 Jun.

Hepassocin is required for hepatic outgrowth during zebrafish hepatogenesis

Authors:
Gao M, Yan H, Yin RH, Wang Q, Zhan YQ, Yu M, Ge CH, Li CY, Wang XH, Ge ZQ, Yang XM
Citation:
Biochem Biophys Res Commun. 2015 Jun 3. pii: S0006-291X(15)30045-0. doi: 10.1016/j.bbrc.2015.05.121. [Epub ahead of print]
Epub:
Yes
Abstract:
Background & aims: Hepassocin (HPS) is a hepatotrophic growth factor that specifically stimulates hepatocyte proliferation...
Organism or Cell Type:
zebrafish
Citation Extract:
Gao M, Yan H, Yin RH, Wang Q, Zhan YQ, Yu M, Ge CH, Li CY, Wang XH, Ge ZQ, Yang XM. Hepassocin is required for hepatic outgrowth during zebrafish hepatogenesis. Biochem Biophys Res Commun. 2015 Jun 3. pii: S0006-291X(15)30045-0. doi: 10.1016/j.bbrc.2015.05.121. [Epub ahead of print].

Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies

Authors:
Ramspacher C, Steed E, Boselli F, Ferreira R, Faggianelli N, Roth S, Spiegelhalter C, Messaddeq N, Trinh L, Liebling M, Chacko N, Tessadori F, Bakkers J, Laporte J, Hnia K, Vermot J
Citation:
Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.05.010
Epub:
Yes
Abstract:
Desminopathies belong to a family of muscle disorders called myofibrillar myopathies that are caused by Desmin mutations and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ramspacher C, Steed E, Boselli F, Ferreira R, Faggianelli N, Roth S, Spiegelhalter C, Messaddeq N, Trinh L, Liebling M, Chacko N, Tessadori F, Bakkers J, Laporte J, Hnia K, Vermot J. Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies. Cell Rep. 2015;[Epub ahead of print] doi:10.1016/j.celrep.2015.05.010.

TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

Authors:
Schmidts M, Hou Y, Cortes CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza J-M, van Beersum SEC, Yap ZM, Letteboer SJF, Taylor SP, Herridge W, Johnson CA, Scambler PJ, Ueffing M, Kayserili H, Krakow D, King SM, Beales PL, Al-Gazali L, Wicking C, Cormier-Daire V, Roepman R, Mitchison HM, Witman GB, UK10K
Citation:
Nat Commun. 2015;[Epub ahead of print] doi:10.1038/ncomms8074
Epub:
Yes
Abstract:
The analysis of individuals with ciliary chondrodysplasias can shed light on sensitive mechanisms controlling ciliogenesis and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schmidts M, Hou Y, Cortes CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza J-M, van Beersum SEC, Yap ZM, Letteboer SJF, Taylor SP, Herridge W, Johnson CA, Scambler PJ, Ueffing M, Kayserili H, Krakow D, King SM, Beales PL, Al-Gazali L, Wicking C, Cormier-Daire V, Roepman R, Mitchison HM, Witman GB, UK10K. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport. Nat Commun. 2015;[Epub ahead of print] doi:10.1038/ncomms8074.

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