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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Xenopus Claudin-6 is required for embryonic pronephros morphogenesis and terminal differentiation

Authors:
Sun J, Wang X, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2015 May 13. pii: S0006-291X(15)00755-X. doi: 10.1016/j.bbrc.2015.04.065. [Epub ahead of print]
Epub:
Yes
Abstract:
Claudins are tetratransmembrane tight junction proteins and play important roles in regulating paracellular permeability of...
Organism or Cell Type:
Xenopus
Citation Extract:
Sun J, Wang X, Li C, Mao B. Xenopus Claudin-6 is required for embryonic pronephros morphogenesis and terminal differentiation. Biochem Biophys Res Commun. 2015 May 13. pii: S0006-291X(15)00755-X. doi: 10.1016/j.bbrc.2015.04.065. [Epub ahead of print].

The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway

Authors:
Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC
Citation:
J Biol Chem. 2015;290:12537-46. doi:10.1074/jbc.M114.616623
Epub:
Not Epub
Abstract:
Wnt signaling plays important roles in both the tumor-induced angiogenesis and tumorigenesis through the transcriptionally...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC. The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway. J Biol Chem. 2015;290:12537-46. doi:10.1074/jbc.M114.616623.

Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart, and brain development

Authors:
Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH
Citation:
Hum Mol Genet. 2015 May 13. pii: ddv180. [Epub ahead of print]
Epub:
Yes
Abstract:
Kabuki syndrome (KS) is a rare multiple congenital anomaly syndrome characterized by distinctive facial features, global...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH. Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart, and brain development. Hum Mol Genet. 2015 May 13. pii: ddv180. [Epub ahead of print].

Two zebrafish hsd3b genes are distinct in function, expression and evolution

Authors:
Lin JC, Hu S, Ho PH, Hsu HJ, Postlethwait J, Chung BC
Citation:
Endocrinology. 2015 May 14:en20141584. [Epub ahead of print]
Epub:
Not Epub
Abstract:
HSD3B catalyzes the synthesis of delta 4 steroids such as progesterone in the adrenals and gonads. Individuals lacking HSD3B2...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin JC, Hu S, Ho PH, Hsu HJ, Postlethwait J, Chung BC. Two zebrafish hsd3b genes are distinct in function, expression and evolution. Endocrinology. 2015 May 14:en20141584. [Epub ahead of print].

Volume changes during active shape fluctuations in cells

Authors:
Taloni A, Kardash E, Salman OU, Truskinovsky L, Zapperi S, La Porta CAM
Citation:
Phys Rev Lett. 2015;[Epub ahead of print]
Epub:
Yes
Abstract:
Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taloni A, Kardash E, Salman OU, Truskinovsky L, Zapperi S, La Porta CAM. Volume changes during active shape fluctuations in cells. Phys Rev Lett. 2015;[Epub ahead of print].

YAP is essential for tissue tension to ensure vertebrate 3D body shape

Authors:
Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki T, Krens SF, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld JB, Link BA, Senga T, Castillo-Morales A, Urrutia AO, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh H, Nishina H, Heisenberg CP, Furutani-Seiki M
Citation:
Nature. 2015 Mar 16. doi: 10.1038/nature14215. [Epub ahead of print]
Epub:
Yes
Abstract:
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki T, Krens SF, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld JB, Link BA, Senga T, Castillo-Morales A, Urrutia AO, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh H, Nishina H, Heisenberg CP, Furutani-Seiki M. YAP is essential for tissue tension to ensure vertebrate 3D body shape. Nature. 2015 Mar 16. doi: 10.1038/nature14215. [Epub ahead of print].

Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis

Authors:
Gago-Rodrigues I, Fernández-Miñán A, Letelier J, Naranjo S, Tena JJ, Gómez-Skarmeta JL, Martinez-Morales JR
Citation:
Nat Commun. 2015 May 12;6:7054. doi: 10.1038/ncomms8054
Epub:
Not Epub
Abstract:
The self-organized morphogenesis of the vertebrate optic cup entails coupling the activation of the retinal gene regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gago-Rodrigues I, Fernández-Miñán A, Letelier J, Naranjo S, Tena JJ, Gómez-Skarmeta JL, Martinez-Morales JR. Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis. Nat Commun. 2015 May 12;6:7054. doi: 10.1038/ncomms8054.

Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine

Authors:
Zhang Y, Kecskés A, Copmans D, Langlois M, Crawford AD, Ceulemans B, Lagae L, de Witte PA, Esguerra CV
Citation:
PLoS One. 2015 May 12;10(5):e0125898. doi: 10.1371/journal.pone.0125898. eCollection 2015
Epub:
Not Epub
Abstract:
Dravet syndrome (DS) is one of the most pharmacoresistant and devastating forms of childhood epilepsy syndromes. Distinct de...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Kecskés A, Copmans D, Langlois M, Crawford AD, Ceulemans B, Lagae L, de Witte PA, Esguerra CV. Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine. PLoS One. 2015 May 12;10(5):e0125898. doi: 10.1371/journal.pone.0125898. eCollection 2015.

Mesoporous silica-coated upconversion nanocrystals for near infrared light-triggered control of gene expression in zebrafish

Authors:
Jayakumar MK, Bansal A, Li BN, Zhang Y
Citation:
Nanomedicine (Lond). 2015 Apr;10(7):1051-61. doi: 10.2217/nnm.14.198
Epub:
Not Epub
Abstract:
AIM: To develop a platform technology for photoactivation of gene expression in deep tissues. MATERIALS & METHODS:...
Organism or Cell Type:
zebrafish
Citation Extract:
Jayakumar MK, Bansal A, Li BN, Zhang Y. Mesoporous silica-coated upconversion nanocrystals for near infrared light-triggered control of gene expression in zebrafish. Nanomedicine (Lond). 2015 Apr;10(7):1051-61. doi: 10.2217/nnm.14.198.

A Potential Contributory Role for Ciliary Dysfunction in the 16p11.2 600 kb BP4-BP5 Pathology

Authors:
Migliavacca E, Golzio C, Männik K, Blumenthal I, Oh EC, Harewood L, Kosmicki JA, Loviglio MN, Giannuzzi G, Hippolyte L, Maillard AM, Alfaiz AA; 16p11.2 European Consortium, van Haelst MM, Andrieux J, Gusella JF, Daly MJ, Beckmann JS, Jacquemont S, Talkowski ME, Katsanis N, Reymond A; 16p11 2 European Consortium
Citation:
Am J Hum Genet. 2015 May 7;96(5):784-96. doi: 10.1016/j.ajhg.2015.04.002. Epub 2015 Apr 30
Epub:
Not Epub
Abstract:
The 16p11.2 600 kb copy-number variants (CNVs) are associated with mirror phenotypes on BMI, head circumference, and brain...
Organism or Cell Type:
zebrafish
Citation Extract:
Migliavacca E, Golzio C, Männik K, Blumenthal I, Oh EC, Harewood L, Kosmicki JA, Loviglio MN, Giannuzzi G, Hippolyte L, Maillard AM, Alfaiz AA; 16p11.2 European Consortium, van Haelst MM, Andrieux J, Gusella JF, Daly MJ, Beckmann JS, Jacquemont S, Talkowski ME, Katsanis N, Reymond A; 16p11 2 European Consortium. A Potential Contributory Role for Ciliary Dysfunction in the 16p11.2 600 kb BP4-BP5 Pathology. Am J Hum Genet. 2015 May 7;96(5):784-96. doi: 10.1016/j.ajhg.2015.04.002. Epub 2015 Apr 30.

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