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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates
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Citation:
Nat Genet. 2015 Oct 5. doi: 10.1038/ng.3376. [Epub ahead of print] Epub:
Yes Abstract:
Heterotaxy results from a failure to establish normal left-right asymmetry early in embryonic development. By whole-exome... Organism or Cell Type:
zebrafish Citation Extract: Guimier A, Gabriel GC, Bajolle F, Tsang M, Liu H, Noll A, Schwartz M, El Malti R, Smith LD, Klena NT, Jimenez G, Miller NA, Oufadem M, Moreau de Bellaing A, Yagi H, Saunders CJ, Baker CN, Di Filippo S, Peterson KA, Thiffault I, Bole-Feysot C, Cooley LD, Farrow EG, Masson C, Schoen P, Deleuze JF, Nitschké P, Lyonnet S, de Pontual L, Murray SA, Bonnet D, Kingsmore SF, Amiel J, Bouvagnet P, Lo CW, Gordon CT. MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates. Nat Genet. 2015 Oct 5. doi: 10.1038/ng.3376. [Epub ahead of print]. |
The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway
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Citation:
Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438 Epub:
Not Epub Abstract:
Small leucine-rich repeat proteoglycan (SLRP) family proteins play important roles in a number of biological events. Here, we... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway. Development. 2015 Oct 1;142(19):3351-61. doi: 10.1242/dev.124438. |
Peptide Nucleic Acid Promotes Systemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice
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Citation:
Mol Ther Nucleic Acids. 2015 Oct 6;4:e255. doi: 10.1038/mtna.2015.27 Epub:
Not Epub Abstract:
Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise for Duchenne muscular dystrophy (DMD)... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Gao X, Shen X, Dong X, Ran N, Han G, Cao L, Gu B, Yin H. Peptide Nucleic Acid Promotes Systemic Dystrophin Expression and Functional Rescue in Dystrophin-deficient mdx Mice. Mol Ther Nucleic Acids. 2015 Oct 6;4:e255. doi: 10.1038/mtna.2015.27. |
Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish
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Citation:
PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 2015 Oct 5;10(10):e0139504. doi: 10.1371/journal.pone.0139504. eCollection 2015. |
Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?
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Citation:
Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6 Epub:
Not Epub Abstract:
Limb body wall complex (LBWC) and amniotic band sequence (ABS) are multiple congenital anomaly conditions with craniofacial,... Organism or Cell Type:
zebrafish Citation Extract: Kruszka P, Uwineza A, Mutesa L, Martinez AF, Abe Y, Zackai EH, Ganetzky R, Chung B, Stevenson RE, Adelstein RS, Ma X, Mullikin JC, Hong SK, Muenke M. Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?. Mol Genet Genomic Med. 2015 Sep;3(5):424-32. doi: 10.1002/mgg3.153. Epub 2015 May 6. |
Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β
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Citation:
Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print] Epub:
Not Epub Abstract:
6-hydroxy-2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) is both a polybrominated diphenyl ether (PBDE) flame... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, Stapleton HM. Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β. Aquat Toxicol. 2015 Sep 24;168:38-47. doi: 10.1016/j.aquatox.2015.09.007. [Epub ahead of print]. |
Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish
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Citation:
Stem Cells Dev. 2015 Sep 28. [Epub ahead of print] Epub:
Yes Abstract:
Growth-arrest-specific 7 (Gas7) is preferentially expressed in the nervous system and plays an important role during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hung FC, Shih HY, Cheng YC, Chao C. Growth-Arrest-Specific 7 Gene Regulates Neural Crest Formation and Craniofacial Development in Zebrafish. Stem Cells Dev. 2015 Sep 28. [Epub ahead of print]. |
Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome
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Citation:
Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print] Epub:
Yes Abstract:
The nuclear pore complex (NPC) is a huge protein complex embedded in the nuclear envelope. It has central functions in... Organism or Cell Type:
zebrafish Citation Extract: Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N. Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome. Am J Hum Genet. 2015 Sep 22. pii: S0002-9297(15)00363-8. doi: 10.1016/j.ajhg.2015.08.013. [Epub ahead of print]. |
Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II
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Citation:
Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print] Epub:
Yes Abstract:
Mucopolysaccharidosis II is a lysosomal storage disorder caused by mutations in the IDS gene, including exonic alterations... Organism or Cell Type:
cell culture: human primary cells Citation Extract: Matos L, Gonçalves V, Pinto E, Laranjeira F, Prata MJ, Jordan P, Desviat LR, Pérez B, Alves S. Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II. Biochim Biophys Acta. 2015 Sep 23. pii: S0925-4439(15)00283-5. doi: 10.1016/j.bbadis.2015.09.011. [Epub ahead of print]. |
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function
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Citation:
Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391 Epub:
Not Epub Abstract:
Membrane proteins are crucial to heart function and development. Here we combine cationic silica-bead coating with shotgun... Organism or Cell Type:
zebrafish Citation Extract: Sharma P, Abbasi C, Lazic S, Teng AC, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391. |