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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Neuropilin-1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain
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Citation:
Development. 2015;[Epub ahead of print] doi: 10.1242/dev.113746 Epub:
Yes Abstract:
Angiogenesis in the developing central nervous system (CNS) is regulated by neuroepithelial cells, although the genes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hirota S, Clements TP, Tang LK, Morales JE, Lee HS, Oh SP, Rivera GM, Wagner DS, McCarty JH. Neuropilin-1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain. Development. 2015;[Epub ahead of print] doi: 10.1242/dev.113746. |
The bHLH Transcription Factor NeuroD Governs Photoreceptor Genesis and Regeneration Through Delta-Notch Signaling
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Citation:
Invest Ophthalmol Vis Sci. 2015 Nov 1;56(12):7496-7515. doi: 10.1167/iovs.15-17616 Epub:
Not Epub Abstract:
Purpose: Photoreceptor genesis in the retina requires precise regulation of progenitor cell competence, cell cycle exit, and... Organism or Cell Type:
zebrafish Citation Extract: Taylor SM, Alvarez-Delfin K, Saade CJ, Thomas JL, Thummel R, Fadool JM, Hitchcock PF. The bHLH Transcription Factor NeuroD Governs Photoreceptor Genesis and Regeneration Through Delta-Notch Signaling. Invest Ophthalmol Vis Sci. 2015 Nov 1;56(12):7496-7515. doi: 10.1167/iovs.15-17616. |
Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes
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Citation:
PNAS. 2015;112(46):E6359-E6368. doi:10.1073/pnas.1516394112 Epub:
Not Epub Abstract:
Anemia is the predominant clinical manifestation of myelodysplastic syndromes (MDS). Loss or deletion of chromosome 7 is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sundaravel S, Duggan R, Bhagat T, Ebenezer DL, Liu H, Yu Y, Bartenstein M, Unnikrishnan M, Karmakar S, Liu T-C, Torregroza I, Quenon T, Anastasi J, McGraw KL, Pellagatti A, Boultwood J, Yajnik V, Artz A, Le Beau MM, Steidl U, List AF, Evans T, Verma A, Wickrema A. Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. PNAS. 2015;112(46):E6359-E6368. doi:10.1073/pnas.1516394112. |
Complete depletion of primordial germ cells in an All-female fish leads to Sex-biased gene expression alteration and sterile All-male occurrence
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Citation:
BMC Genomics. 2015;16:971 doi:10.1186/s12864-015-2130-z Epub:
Not Epub Abstract:
Background: Gynogenesis is one of unisexual reproduction modes in vertebrates, and produces all-female individuals with... Delivery Method:
microinjection Organism or Cell Type:
Carassius gibelio (Prussian carp) Citation Extract: Liu W, Li S-Z, Li Z, Wang Y, Li X-Y, Zhong J-X, Zhang X-J, Zhang J, Zhou L, Gui J-F. Complete depletion of primordial germ cells in an All-female fish leads to Sex-biased gene expression alteration and sterile All-male occurrence. BMC Genomics. 2015;16:971 doi:10.1186/s12864-015-2130-z. |
Nr2f1b control venous specification and angiogenic patterning during zebrafish vascular development
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Citation:
J Biomed Sci. 2015;22:104. doi:10.1186/s12929-015-0209-0 Epub:
Yes Abstract:
Background: The specification of vein and the patterning of intersegmental vessels (ISV) controlled by transcription factor is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li R-F, Wu T-Y, Mou Y-Z, Wang Y-S, Chen C-L, Wu C-Y. Nr2f1b control venous specification and angiogenic patterning during zebrafish vascular development. J Biomed Sci. 2015;22:104. doi:10.1186/s12929-015-0209-0. |
Longitudinal effect of eteplirsen vs. historical control on ambulation in DMD
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Citation:
Ann Neurol. 2015;[Epub ahead of print] doi:10.1002/ana.24555 Epub:
Yes Abstract:
Objectives: To continue evaluation of the long-term efficacy and safety of eteplirsen, a phosphorodiamidate morpholino oligomer... Delivery Method:
infusion i.v. Organism or Cell Type:
humans Citation Extract: Mendell JR, Goemans N, Lowes LP, Alfano LN, Berry K, Shao J, Kaye EM, Mercuri E, Eteplirsen Study Group, DMD Italian Network. Longitudinal effect of eteplirsen vs. historical control on ambulation in DMD. Ann Neurol. 2015;[Epub ahead of print] doi:10.1002/ana.24555. |
Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells
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Citation:
Skeletal Muscle. 2015;5:40. doi:10.1186/s13395-015-0062-6 Epub:
Not Epub Abstract:
Background: Duchenne muscular dystrophy (DMD) is a devastating X-linked recessive genetic myopathy. DMD physiopathology is... Delivery Method:
electroporation Organism or Cell Type:
cell culture: hiPSCs Citation Extract: Massouridès E, Polentes J, Mangeot P-E, Mournetas V, Nectoux J, Deburgrave N, Nusbaum P, Leturcq F, Popplewell L, Dickson G, Wein N, Flanigan KM, Peschanski M, Chelly J, Pinset C. Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells. Skeletal Muscle. 2015;5:40. doi:10.1186/s13395-015-0062-6. |
Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway
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Citation:
Sci Rep. 2015;5:16815. doi:10.1038/srep16815 Epub:
Not Epub Abstract:
Formononetin is an isoflavone that has been shown to display estrogenic properties and induce angiogenesis activities. However... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li S, Dang Y, Zhou X, Huang B, Huang X, Zhang Z, Kwan YW, Chan SW, Leung GPH, Lee SMY, Hoi MPM. Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway. Sci Rep. 2015;5:16815. doi:10.1038/srep16815. |
The Effects of Hsp90α1 Mutations on Myosin Thick Filament Organization
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Citation:
PLoS ONE. 2015;10(11):e0142573. doi:10.1371/journal.pone.0142573 Epub:
Not Epub Abstract:
Heat shock protein 90α plays a key role in myosin folding and thick filament assembly in muscle cells. To assess the structure... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He Q, Liu K, Tian Z, Du SJ. The Effects of Hsp90α1 Mutations on Myosin Thick Filament Organization. PLoS ONE. 2015;10(11):e0142573. doi:10.1371/journal.pone.0142573. |
Individual Members of the Microbiota Disproportionately Modulate Host Innate Immune Responses
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Citation:
Cell Host Microbe. 2015;18(5):613-20. doi:10.1016/j.chom.2015.10.009 Epub:
Not Epub Abstract:
Predicting host health status based on microbial community structure is a major goal of microbiome research. An implicit... Organism or Cell Type:
zebrafish Citation Extract: Rolig AS, Parthasarathy R, Burns AR, Bohannan BJM, Guillemin K. Individual Members of the Microbiota Disproportionately Modulate Host Innate Immune Responses. Cell Host Microbe. 2015;18(5):613-20. doi:10.1016/j.chom.2015.10.009. |