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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

TGF-β Controls miR-181/ERK Regulatory Network during Retinal Axon Specification and Growth

Authors:
Carrella S, Barbato S, D'Agostino Y, Salierno FG, Manfredi A, Banfi S, Conte I
Citation:
PLoS One. 2015 Dec 7;10(12):e0144129. doi: 10.1371/journal.pone.0144129. eCollection 2015
Epub:
Not Epub
Abstract:
Retinal axon specification and growth are critically sensitive to the dosage of numerous signaling molecules and transcription...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Carrella S, Barbato S, D'Agostino Y, Salierno FG, Manfredi A, Banfi S, Conte I. TGF-β Controls miR-181/ERK Regulatory Network during Retinal Axon Specification and Growth. PLoS One. 2015 Dec 7;10(12):e0144129. doi: 10.1371/journal.pone.0144129. eCollection 2015.

POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking

Authors:
Schindler RF, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon KL, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T, Ferlini A
Citation:
J Clin Invest. 2015 Dec 7. pii: 79562. doi: 10.1172/JCI79562. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Popeye domain-containing 1 (POPDC1) gene encodes a plasma membrane-localized cAMP-binding protein that is abundantly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schindler RF, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon KL, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T, Ferlini A. POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking. J Clin Invest. 2015 Dec 7. pii: 79562. doi: 10.1172/JCI79562. [Epub ahead of print].

The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells

Authors:
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G
Citation:
J Cell Biol. 2015;211(5):964-73. doi:10.1083/jcb.201502043
Epub:
Not Epub
Abstract:
Motile cilia polarization requires intracellular anchorage to the cytoskeleton; however, the molecular machinery that supports...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G. The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. J Cell Biol. 2015;211(5):964-73. doi:10.1083/jcb.201502043.

Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type

Authors:
Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, Koparir E, Karaca E, Katsanis N, Marton V, Vermeesch JR, Davis EE, Cowan NJ, Keays DA, Van Esch H
Citation:
Am J Hum Gen. 2015;97(6):790-800. doi:10.1016/j.ajhg.2015.10.014
Epub:
Not Epub
Abstract:
Circumferential skin creases Kunze type (CSC-KT) is a specific congenital entity with an unknown genetic cause. The disease...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, Koparir E, Karaca E, Katsanis N, Marton V, Vermeesch JR, Davis EE, Cowan NJ, Keays DA, Van Esch H. Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type. Am J Hum Gen. 2015;97(6):790-800. doi:10.1016/j.ajhg.2015.10.014.

PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination

Authors:
Kim J-D, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A
Citation:
Sci Adv. 2015;1:e1500615 doi:10.1126/sciadv.1500615
Epub:
Not Epub
Abstract:
The development of vertebrate neurons requires a change in membrane phosphatidylcholine (PC) metabolism. Although PC hydrolysis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim J-D, Park KE, Ishida J, Kako K, Hamada J, Kani S, Takeuchi M, Namiki K, Fukui H, Fukuhara S, Hibi M, Kobayashi M, Kanaho Y, Kasuya Y, Mochizuki N, Fukamizu A. PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination. Sci Adv. 2015;1:e1500615 doi:10.1126/sciadv.1500615.

Cortisol Regulates Acid Secretion of H+-ATPase-rich Ionocytes in Zebrafish (Danio rerio) Embryos

Authors:
Lin CH, Shih TH, Liu ST, Hsu HH, Hwang PP
Citation:
Front Physiol. 2015 Nov 17;6:328. eCollection 2015
Epub:
Not Epub
Abstract:
Systemic acid-base regulation is vital for physiological processes in vertebrates. Freshwater (FW) fish live in an inconstant...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CH, Shih TH, Liu ST, Hsu HH, Hwang PP. Cortisol Regulates Acid Secretion of H+-ATPase-rich Ionocytes in Zebrafish (Danio rerio) Embryos. Front Physiol. 2015 Nov 17;6:328. eCollection 2015.

Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway

Authors:
Yeh CW, Hsu LS
Citation:
Mol Neurobiol. 2015 Dec 3. [Epub ahead of print]
Epub:
Yes
Abstract:
The small GTPase Ras superfamily regulates several neuronal functions including neurite outgrowth and neuron proliferation. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yeh CW, Hsu LS. Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway. Mol Neurobiol. 2015 Dec 3. [Epub ahead of print].

A nonsynonymous mutation in the transcriptional regulator lbh is associated with cichlid craniofacial adaptation and neural crest cell development

Authors:
Powder KE, Cousin H, McLinden GP, Albertson RC
Citation:
Mol Biol Evol. 2014 Dec;31(12):3113-24. doi: 10.1093/molbev/msu267. Epub 2014 Sep 18
Epub:
Not Epub
Abstract:
Since the time of Darwin, biologists have sought to understand the origins and maintenance of life's diversity of form....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Powder KE, Cousin H, McLinden GP, Albertson RC. A nonsynonymous mutation in the transcriptional regulator lbh is associated with cichlid craniofacial adaptation and neural crest cell development. Mol Biol Evol. 2014 Dec;31(12):3113-24. doi: 10.1093/molbev/msu267. Epub 2014 Sep 18.

Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

Authors:
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S
Citation:
Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11
Epub:
Not Epub
Abstract:
Dysregulation of the actin cytoskeleton in podocytes represents a common pathway in the pathogenesis of proteinuria across a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11.

Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids

Authors:
Carver K, Ming X, Juliano RL
Citation:
Nucleic Acid Ther. 2014 Dec;24(6):413-9. doi: 10.1089/nat.2014.0493
Epub:
Not Epub
Abstract:
Standard tissue culture has often been a poor model for predicting the efficacy of anti-cancer agents including...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: A375 human melanoma, human dermal fibroblasts, multicellular tumor spheroids (MCTS)
Citation Extract:
Carver K, Ming X, Juliano RL. Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids. Nucleic Acid Ther. 2014 Dec;24(6):413-9. doi: 10.1089/nat.2014.0493.

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