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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression
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Citation:
Nat Comm. 2016;7:11317. doi:15.13155/ncomms11317 Epub:
Not Epub Abstract:
Calcium signalling plays a critical role in the pathogenesis of heart failure. Here we describe a cardiac protein named... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M, German Mouse Clinic Consortium, de Angelis MH, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N. Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression. Nat Comm. 2016;7:11317. doi:15.13155/ncomms11317. |
Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides
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Citation:
PLoS ONE. 2016;11(4): e0154723. doi:10.1371/journal.pone.0154723 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease caused by deficiency of the survival of motor... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
mice Citation Extract: Lin T-L, Chen T-H, Hsu Y-Y, Cheng Y-H, Juang B-T, Jong Y-J. Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides. PLoS ONE. 2016;11(4): e0154723. doi:10.1371/journal.pone.0154723. |
Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA
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Citation:
Bioorg Med Chem Lett. 2016 Apr 11. pii: S0960-894X(16)30386-9. doi: 10.1016/j.bmcl.2016.04.025. [Epub ahead of print] Epub:
Yes Abstract:
Potential RNA targets for chemical probes and therapeutic modalities are pervasive in the transcriptome. Oligonucleotide-based... Delivery Method:
Vivo-Morpholino Citation Extract: Costales MG, Rzuczek SG, Disney MD. Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA. Bioorg Med Chem Lett. 2016 Apr 11. pii: S0960-894X(16)30386-9. doi: 10.1016/j.bmcl.2016.04.025. [Epub ahead of print]. |
The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion
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Citation:
Hepatology. 2016 Apr 26. doi: 10.1002/hep.28622. [Epub ahead of print] Epub:
Yes Abstract:
The secretin/secretin receptor (SR) axis is upregulated by proliferating cholangiocytes during cholestasis. Secretin stimulates... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Wu N, Meng F, Invernizzi P, Bernuzzi F, Venter J, Standeford H, Onori P, Marzioni M, Alvaro D, Franchitto A, Gaudio E, Glaser S, Alpini G. The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion. Hepatology. 2016 Apr 26. doi: 10.1002/hep.28622. [Epub ahead of print]. |
Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae
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Citation:
J Neural Transm (Vienna). 2016 Apr 26. [Epub ahead of print] Epub:
Not Epub Abstract:
First line pain relief medication during pregnancy relies nearly entirely on the over-the-counter analgesic acetaminophen,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reuter I, Knaup S, Romanos M, Lesch KP, Drepper C, Lillesaar C. Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae. J Neural Transm (Vienna). 2016 Apr 26. [Epub ahead of print]. |
Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner
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Citation:
Biochem Pharmacol. 2016 Apr 22. pii: S0006-2952(16)30066-1. doi: 10.1016/j.bcp.2016.04.012. [Epub ahead of print] Epub:
Yes Abstract:
6-Formylindolo[3,2-b]carbazole (FICZ) is a potent aryl hydrocarbon receptor (AHR) agonist that is efficiently metabolized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wincent E, Kubota A, Timme-Laragy A, Jönsson ME, Hahn ME, Stegeman JJ. Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner. Biochem Pharmacol. 2016 Apr 22. pii: S0006-2952(16)30066-1. doi: 10.1016/j.bcp.2016.04.012. [Epub ahead of print]. |
sept7b is required for the differentiation of pancreatic endocrine progenitors
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Citation:
Sci Rep. 2016;6:27992. doi:10.1038/srep24992 Epub:
Not Epub Abstract:
Protection or restoration of pancreatic β-cell mass as a therapeutic treatment for type 1 diabetes requires understanding of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dash SN, Hakonen E, Ustinov J, Otonkoski T, Andersson O, Lehtonen S. sept7b is required for the differentiation of pancreatic endocrine progenitors. Sci Rep. 2016;6:27992. doi:10.1038/srep24992. |
An Electrochemical Study of the Surface Hybridization Process of Morpholino-DNA: Thermodynamics and Kinetics
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Citation:
Electroanalysis. 2016;[Epub ahead of print] doi:10.1002/elan.201501109 Epub:
Not Epub Abstract:
Morpholino (MO) is a neutral analogue of DNA, which shows promise in the development of DNA biosensors and diagnostic devices.... Citation Extract: He Y, Zhang J, Ruffin S, Ji L, Wang K, Levicky R, Xia X
. An Electrochemical Study of the Surface Hybridization Process of Morpholino-DNA: Thermodynamics and Kinetics. Electroanalysis. 2016;[Epub ahead of print] doi:10.1002/elan.201501109. |
Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesis
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Citation:
Nat Commun. 2016 Apr 18;7:11288. doi: 10.1038/ncomms11288 Epub:
Not Epub Abstract:
The precise positioning of organ progenitor cells constitutes an essential, yet poorly understood step during organogenesis.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paksa A, Bandemer J, Hoeckendorf B, Razin N, Tarbashevich K, Minina S, Meyen D, Biundo A, Leidel SA, Peyrieras N, Gov NS, Keller PJ, Raz E. Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesis. Nat Commun. 2016 Apr 18;7:11288. doi: 10.1038/ncomms11288. |
Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development
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Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.03.072 Epub:
Yes Abstract:
Error-prone repair of DNA double-strand breaks (DSBs) has been postulated to occur through classical non-homologous end joining... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thyme SB, Schier AF. Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.03.072. |