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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Translational Inhibition of CTX-M Extended Spectrum β-Lactamase in Clinical Strains of Escherichia coli by Synthetic Antisense Oligonucleotides Partially Restores Sensitivity to Cefotaxime
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Citation:
Front Microbiol. 2016 Mar 24;7:373. eCollection 2016 Epub:
Not Epub Abstract:
Synthetic antisense oligomers are DNA mimics that can specifically inhibit gene expression at the translational level by... Delivery Method:
peptide-linked Organism or Cell Type:
Escherichia coli Citation Extract: Readman JB, Dickson G, Coldham NG. Translational Inhibition of CTX-M Extended Spectrum β-Lactamase in Clinical Strains of Escherichia coli by Synthetic Antisense Oligonucleotides Partially Restores Sensitivity to Cefotaxime. Front Microbiol. 2016 Mar 24;7:373. eCollection 2016. |
Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast
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Citation:
J Biol Chem. 2015 Mar 27;290(13):8331-47. doi: 10.1074/jbc.M114.615088. Epub 2015 Feb 5 Epub:
Not Epub Abstract:
The CCR4-NOT complex, the major deadenylase in eukaryotes, plays crucial roles in gene expression at the levels of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Makino S, Mishima Y, Inoue K, Inada T. Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast. J Biol Chem. 2015 Mar 27;290(13):8331-47. doi: 10.1074/jbc.M114.615088. Epub 2015 Feb 5. |
Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock
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Citation:
Elife. 2016 Feb 13;5. pii: e08438. doi: 10.7554/eLife.08438 Epub:
Not Epub Abstract:
In vertebrate development, the sequential and rhythmic segmentation of the body axis is regulated by a "segmentation clock... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Webb AB, Lengyel IM, Jörg DJ, Valentin G, Jülicher F, Morelli LG, Oates AC. Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock. Elife. 2016 Feb 13;5. pii: e08438. doi: 10.7554/eLife.08438. |
ATR promotes cilia signalling: links to developmental impacts
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Citation:
Hum Mol Genet. 2016 Apr 15;25(8):1574-87. doi: 10.1093/hmg/ddw034. Epub 2016 Feb 11 Epub:
Not Epub Abstract:
Mutations in ATR (ataxia telangiectasia and RAD3-related) cause Seckel syndrome (ATR-SS), a microcephalic primordial dwarfism... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Stiff T, Casar Tena T, O'Driscoll M, Jeggo PA, Philipp M. ATR promotes cilia signalling: links to developmental impacts. Hum Mol Genet. 2016 Apr 15;25(8):1574-87. doi: 10.1093/hmg/ddw034. Epub 2016 Feb 11. |
The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress
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Citation:
J Alzheimers Dis. 2016 Mar 31. [Epub ahead of print] Epub:
Yes Abstract:
Dominant mutations in the PRESENILIN genes PSEN1 and PSEN2 cause familial Alzheimer's disease (fAD) that usually shows... Organism or Cell Type:
zebrafish Citation Extract: Ebrahimie E, Moussavi-Nik SH, Newman M, Van Der Hoek M, Lardelli M. The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. J Alzheimers Dis. 2016 Mar 31. [Epub ahead of print]. |
Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish
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Citation:
Genes Cells. 2016 Mar 29. doi: 10.1111/gtc.12358. [Epub ahead of print] Epub:
Yes Abstract:
The adenohypophysis (AH) consists of six distinct types of hormone-secreting cells. In zebrafish, although proper... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nakahara Y, Muto A, Hirabayashi R, Sakuma T, Yamamoto T, Kume S, Kikuchi Y. Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish. Genes Cells. 2016 Mar 29. doi: 10.1111/gtc.12358. [Epub ahead of print]. |
APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p
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Citation:
Nat Commun. 2015 Apr 10;6:6779. doi: 10.1038/ncomms7779 Epub:
Not Epub Abstract:
The abnormal autophagy is associated with a variety of cardiovascular diseases. Long noncoding RNAs (lncRNAs) are emerging as... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: mouse primary cardiomyocytes Citation Extract: Wang K, Liu CY, Zhou LY, Wang JX, Wang M, Zhao B, Zhao WK, Xu SJ, Fan LH, Zhang XJ, Feng C, Wang CQ, Zhao YF, Li PF. APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p. Nat Commun. 2015 Apr 10;6:6779. doi: 10.1038/ncomms7779. |
Correction of the Pathogenic Alternative Splicing, Caused by the Common GNB3 c.825C>T allele, Using a Novel, Antisense Morpholino
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Citation:
Nucleic Acid Ther. 2016 Mar 30. [Epub ahead of print] Epub:
Yes Abstract:
The very common GNB3 c.825C>T polymorphism (rs5443) is present in approximately half of all human chromosomes. Significantly... Organism or Cell Type:
cell culture: human lymphoblast cell line ebv transformed Citation Extract: McGlinchey JC, Tummala H, Lester DH. Correction of the Pathogenic Alternative Splicing, Caused by the Common GNB3 c.825C>T allele, Using a Novel, Antisense Morpholino. Nucleic Acid Ther. 2016 Mar 30. [Epub ahead of print]. |
4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation
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Citation:
JCI. 2016;[Epub ahead of print] doi:10.1172/JCI83496 Epub:
Yes Abstract:
Hemodynamic shear forces are intimately linked with cardiac development, during which trabeculae form a network of branching... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee J, Fei P, Packard RRS, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Jay Kuo CCJ, Chi NC, Ho C-M, Li R, Hsiai TK. 4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation. JCI. 2016;[Epub ahead of print] doi:10.1172/JCI83496. |
Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo
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Citation:
J Cell Biol. 2016;[Epub ahead of print] doi:10.1083/jcb.201510019 Epub:
Yes Abstract:
Increasing evidence implicates Ca2+ in the control of cell migration. However, the underlying mechanisms are incompletely... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Melchionda M, Pittman JK, Mayor R, Patel S. Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo. J Cell Biol. 2016;[Epub ahead of print] doi:10.1083/jcb.201510019. |