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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Elusive sources of variability of dystrophin rescue by exon skipping
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Citation:
Skelet Muscle. 2015 Dec 1;5:44. eCollection 2015 Epub:
Not Epub Abstract:
BACKGROUND: Systemic delivery of anti-sense oligonucleotides to Duchenne muscular dystrophy (DMD) patients to induce de novo... Delivery Method:
injection iv retro-orbital Organism or Cell Type:
mice, mdx Citation Extract: Vila MC, Klimek MB, Novak JS, Rayavarapu S, Uaesoontrachoon K, Boehler JF, Fiorillo AA, Hogarth MW, Zhang A, Shaughnessy C, Gordish-Dressman H, Burki U, Straub V, Lu QL, Partridge TA, Brown KJ, Hathout Y, van den Anker J, Hoffman EP, Nagaraju K. Elusive sources of variability of dystrophin rescue by exon skipping. Skelet Muscle. 2015 Dec 1;5:44. eCollection 2015. |
Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
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Citation:
Genome Biol. 2015;16:267 doi:10.1186/s13059-015-0825-8 Epub:
Not Epub Abstract:
Background: Mutations in myosin chaperones Unc45b and Hsp90aa1.1 as well as in the Unc45b-binding protein Smyd1b impair... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Etard C, Armant O, Roostalu U, Gourain V, Ferg M, Strähle U. Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells. Genome Biol. 2015;16:267 doi:10.1186/s13059-015-0825-8. |
Whole USH2A Gene Sequencing Identifies Several New Deep Intronic Mutations
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Citation:
Hum Mutat. 2015 Nov 2. doi: 10.1002/humu.22926. [Epub ahead of print] Epub:
Yes Abstract:
Deep intronic mutations leading to pseudoexon (PE) insertions are underestimated and most of these splicing alterations have... Organism or Cell Type:
cell culture Citation Extract: Liquori A, Vaché C, Baux D, Blanchet C, Hamel C, Malcolm S, Koenig M, Claustres M, Roux AF. Whole USH2A Gene Sequencing Identifies Several New Deep Intronic Mutations. Hum Mutat. 2015 Nov 2. doi: 10.1002/humu.22926. [Epub ahead of print]. |
Disruption of Epithalamic Left-Right Asymmetry Increases Anxiety in Zebrafish
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Citation:
J Neurosci. 2015;35(48):15847-59. doi:10.1523/JNEUROSCI.2593-15.2015 Epub:
Not Epub Abstract:
Differences between the left and right sides of the brain are found throughout the animal kingdom, but the consequences of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Facchin L, Duboué ER, Halpern ME. Disruption of Epithalamic Left-Right Asymmetry Increases Anxiety in Zebrafish. J Neurosci. 2015;35(48):15847-59. doi:10.1523/JNEUROSCI.2593-15.2015. |
A Zebrafish Model for Studies on Esophageal Epithelial Biology
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Citation:
PLoS ONE. 2015;10(12):e0143878. doi:10.1371/journal.pone.0143878 Epub:
Not Epub Abstract:
Mammalian esophagus exhibits a remarkable change in epithelial structure during the transition from embryo to adult. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen H, Beasley A, Hu Y, Chen X. A Zebrafish Model for Studies on Esophageal Epithelial Biology. PLoS ONE. 2015;10(12):e0143878. doi:10.1371/journal.pone.0143878. |
The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish
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Citation:
PLoS Genet. 2015 Dec 1;11(12):e1005677. doi: 10.1371/journal.pgen.1005677. eCollection 2015 Dec Epub:
Not Epub Abstract:
Ribosome biogenesis is a ubiquitous and essential process in cells. Defects in ribosome biogenesis and function result in a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bielczyk-Maczyńska E, Lam Hung L, Ferreira L, Fleischmann T, Weis F, Fernández-Pevida A, Harvey SA, Wali N, Warren AJ, Barroso I, Stemple DL, Cvejic A. The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish. PLoS Genet. 2015 Dec 1;11(12):e1005677. doi: 10.1371/journal.pgen.1005677. eCollection 2015 Dec. |
Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7
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Citation:
PLoS One. 2015 Nov 30;10(11):e0143825. doi: 10.1371/journal.pone.0143825. eCollection 2015 Epub:
Not Epub Abstract:
Retinol binding proteins (Rbps) are known as carriers for transport and targeting of retinoids to their metabolizing enzymes.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen H, Babino D, Schoenbichler SA, Arkhipova V, Töchterle S, Martin F, Huck CW, von Lintig J, Meyer D. Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7. PLoS One. 2015 Nov 30;10(11):e0143825. doi: 10.1371/journal.pone.0143825. eCollection 2015. |
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish
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Citation:
Elife. 2015 Oct 16;4. pii: e09406. doi: 10.7554/eLife.09406 Epub:
Not Epub Abstract:
Truncating mutations in the giant sarcomeric protein Titin result in dilated cardiomyopathy and skeletal myopathy. The most... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Elife. 2015 Oct 16;4. pii: e09406. doi: 10.7554/eLife.09406. |
RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure
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Citation:
J Clin Invest. 2015 Nov 30. pii: 84015. doi: 10.1172/JCI84015. [Epub ahead of print] Epub:
Yes Abstract:
RNA splicing is a major contributor to total transcriptome complexity; however, the functional role and regulation of splicing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y. RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. J Clin Invest. 2015 Nov 30. pii: 84015. doi: 10.1172/JCI84015. [Epub ahead of print]. |
Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish
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Citation:
Development 2015 142: 4080-4091; doi: 10.1242/dev.125724 Epub:
Not Epub Abstract:
Congenital heart disease often features structural abnormalities that emerge during development. Accumulating evidence... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Samsa LA, Givens C, Tzima E, Stainier DYR, Qian L, Liu J. Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish. Development 2015 142: 4080-4091; doi: 10.1242/dev.125724. |