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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

pdzrn3 is required for pronephros morphogenesis in Xenopus laevis

Authors:
Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L
Citation:
Int J Dev Biol. 2016 Mar 2. [Epub ahead of print]
Epub:
Yes
Abstract:
Pdzrn3, a multidomain protein with E3-ubiquitin ligase activity, has been reported to play a role in myoblast and osteoblast...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Marracci S, Vangelisti A, Raffa V, Andreazzoli M, Dente L. pdzrn3 is required for pronephros morphogenesis in Xenopus laevis. Int J Dev Biol. 2016 Mar 2. [Epub ahead of print].

Halogenated carbazoles induce cardiotoxicity in developing zebrafish embryos (Danio rerio)

Authors:
Fang M, Guo J, Chen D, Li A, Hinton DE, Dong W
Citation:
Environ Toxicol Chem. 2016 Mar 2. doi: 10.1002/etc.3416. [Epub ahead of print]
Epub:
Yes
Abstract:
Halogenated carbazoles are increasingly identified as a novel class of environmental contaminants. However, no in vivo acute...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fang M, Guo J, Chen D, Li A, Hinton DE, Dong W. Halogenated carbazoles induce cardiotoxicity in developing zebrafish embryos (Danio rerio). Environ Toxicol Chem. 2016 Mar 2. doi: 10.1002/etc.3416. [Epub ahead of print].

The Lhx9-Integrin pathway is essential for positioning of the proepicardial organ

Authors:
Tandon P, Wilczewski CM, Williams CE, Conlon FL
Citation:
Development. 2016 Jan 25. pii: dev.129551. [Epub ahead of print]
Epub:
Yes
Abstract:
The development of the vertebrate embryonic heart occurs by hyperplastic growth as well as the incorporation of cells from...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tandon P, Wilczewski CM, Williams CE, Conlon FL. The Lhx9-Integrin pathway is essential for positioning of the proepicardial organ. Development. 2016 Jan 25. pii: dev.129551. [Epub ahead of print].

Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement

Authors:
Verstraeten B, van Hengel J, Huysseune A
Citation:
PLoS ONE. 2016;11(3):e0148114. doi:10.1371/journal.pone.0148114
Epub:
Not Epub
Abstract:
We analyzed the protein distribution of two cadherin-associated molecules, plakoglobin and β-catenin, during the different...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Verstraeten B, van Hengel J, Huysseune A . Beta-Catenin and Plakoglobin Expression during Zebrafish Tooth Development and Replacement. PLoS ONE. 2016;11(3):e0148114. doi:10.1371/journal.pone.0148114.

Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy

Authors:
Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung MY
Citation:
Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print]
Epub:
Yes
Abstract:
Familial exudative vitreoretinopathy (FEVR) belongs to a group of genetically and clinically heterogeneous disorders in retinal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu JH, Liu JH, Ko YC, Wang CT, Chung YC, Chu KC, Liu TT, Chao HM, Jiang YJ, Chen SJ, Chung MY. Haploinsufficiency of RCBTB1 is Associated with Coats Disease and Familial Exudative Vitreoretinopathy. Hum Mol Genet. 2016 Feb 11. pii: ddw041. [Epub ahead of print].

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

Authors:
Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH
Citation:
Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666
Epub:
Not Epub
Abstract:
The Src family kinase (SFK) member SRC is a major target in drug development because it is activated in many human cancers, yet...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SVV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C, BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Sci Transl Med. 2016;8(328):328ra30 doi:10.1126/scitranslmed.aad7666.

Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy

Authors:
Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L
Citation:
Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print]
Epub:
Yes
Abstract:
Mitochondria are the site of iron utilization, wherein imported iron is incorporated into heme or iron-sulfur clusters....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L. Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy. Proc Natl Acad Sci U S A. 2016 Feb 29. pii: 201600077. [Epub ahead of print].

Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs

Authors:
Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL
Citation:
Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL. Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3.

Active DNA demethylation at enhancers during the vertebrate phylotypic period

Authors:
Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R
Citation:
Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print]
Epub:
Yes
Abstract:
The vertebrate body plan and organs are shaped during a conserved embryonic phase called the phylotypic stage. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R. Active DNA demethylation at enhancers during the vertebrate phylotypic period. Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print].

Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation

Authors:
Guillon E, Bretaud S, Ruggiero F
Citation:
J Neurosci. 2016;36(9):2663-76. doi:10.1523/JNEUROSCI.2847-15.2016
Epub:
Not Epub
Abstract:
The extracellular matrix (ECM) provides local positional information to guide motoneuron axons toward their muscle target....
Organism or Cell Type:
zebrafish
Citation Extract:
Guillon E, Bretaud S, Ruggiero F. Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation. J Neurosci. 2016;36(9):2663-76. doi:10.1523/JNEUROSCI.2847-15.2016.

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