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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Epigenetic activation of Sox2 gene in the developing vertebrate neural plate

Authors:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH
Citation:
Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20
Epub:
Not Epub
Abstract:
One of the earliest manifestations of neural induction is onset of expression of the neural marker Sox2, mediated by the...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bouzas SO, Marini MS, Torres Zelada E, Buzzi AL, Morales Vicente DA, Strobl-Mazzulla PH. Epigenetic activation of Sox2 gene in the developing vertebrate neural plate. Mol Biol Cell. 2016 Jun 15;27(12):1921-7. doi: 10.1091/mbc.E16-01-0042. Epub 2016 Apr 20.

Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells

Authors:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T
Citation:
Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595
Epub:
Yes
Abstract:
Purpose: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive human T-cell malignancy induced by human T-lymphotrophic virus-...
Organism or Cell Type:
cell culture: adult T-cell leukemia/lymphoma cells
Citation Extract:
Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T. Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells. Clin Cancer Res. 2016 Dec 1;22(23):5915-5928. doi: 10.1158/1078-0432.CCR-15-1739. Epub 2016 Jun 15. PMID: 27307595.

A novel function of calcitonin gene-related peptide in body fluid Cl− homeostasis

Authors:
Wang Y-F, Lafont A-G, Lee Y-C, Hwang P-P
Citation:
Proc Royal Soc B Biol. 2016;[Epub ahead of print] doi:10.1098/rspb.2016.0684
Epub:
Yes
Abstract:
Vertebrates need to maintain extracellular chloride (Cl−) concentrations to ensure the normal operation of physiological...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y-F, Lafont A-G, Lee Y-C, Hwang P-P. A novel function of calcitonin gene-related peptide in body fluid Cl− homeostasis. Proc Royal Soc B Biol. 2016;[Epub ahead of print] doi:10.1098/rspb.2016.0684.

Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos

Authors:
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM
Citation:
Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi:10.1289/EHP141
Epub:
Yes
Abstract:
Exposure to the commonly used dithiocarbamate (DTC) pesticide ziram is associated with an increased risk of developing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM. Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos. Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi:10.1289/EHP141.

Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated α-dystroglycan

Authors:
Marchese M, Pappalardo A, Baldacci J, Verri T, Doccini S, Cassandrini D, Bruno C, Fiorillo C, Garcia-Gil M, Bertini E, Pitto L, Santorelli FM
Citation:
Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30951-2. doi: 10.1016/j.bbrc.2016.06.033. [Epub ahead of print]
Epub:
Yes
Abstract:
Defective dolichol-phosphate mannose synthase (DPMS) complex is a rare cause of congenital muscular dystrophy associated with...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marchese M, Pappalardo A, Baldacci J, Verri T, Doccini S, Cassandrini D, Bruno C, Fiorillo C, Garcia-Gil M, Bertini E, Pitto L, Santorelli FM. Dolichol-phosphate mannose synthase depletion in zebrafish leads to dystrophic muscle with hypoglycosylated α-dystroglycan. Biochem Biophys Res Commun. 2016 Jun 9. pii: S0006-291X(16)30951-2. doi: 10.1016/j.bbrc.2016.06.033. [Epub ahead of print].

Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation

Authors:
Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH
Citation:
Cell Death Differ. 2016 Jun 10. doi: 10.1038/cdd.2016.54. [Epub ahead of print]
Epub:
Yes
Abstract:
Merlin, encoded by the NF2 gene, is a tumor suppressor that acts by inhibiting mitogenic signaling and is mutated in...
Citation Extract:
Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH. Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation. Cell Death Differ. 2016 Jun 10. doi: 10.1038/cdd.2016.54. [Epub ahead of print].

Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer

Authors:
Zhang JF, Jiang Z, Liu X, Meng A
Citation:
Development. 2016 Jun 10. pii: dev.132969. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The kupffer's vesicle (KV) is the so-called left-right organizer in teleost fishes. KV is formed from dorsal forerunner...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang JF, Jiang Z, Liu X, Meng A. Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016 Jun 10. pii: dev.132969. [Epub ahead of print].

Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy

Authors:
Miskew Nichols B, Aoki Y, Kuraoka M, Lee JJ, Takeda S, Yokota T
Citation:
J Vis Exp. 2016 May 24;(111). doi: 10.3791/53776
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is one of the most common lethal genetic diseases worldwide, caused by mutations in the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Canis familiaris (dog)
Citation Extract:
Miskew Nichols B, Aoki Y, Kuraoka M, Lee JJ, Takeda S, Yokota T. Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy. J Vis Exp. 2016 May 24;(111). doi: 10.3791/53776.

Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules

Authors:
Nakamura Y, de Paiva Alves E, Veenstra GJ, Hoppler S
Citation:
Development. 2016 Jun 1;143(11):1914-25. doi: 10.1242/dev.131664. Epub 2016 Apr 11
Epub:
Not Epub
Abstract:
Key signalling pathways, such as canonical Wnt/β-catenin signalling, operate repeatedly to regulate tissue- and stage-specific...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Nakamura Y, de Paiva Alves E, Veenstra GJ, Hoppler S. Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules. Development. 2016 Jun 1;143(11):1914-25. doi: 10.1242/dev.131664. Epub 2016 Apr 11.

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration

Authors:
Taylor KM, Muraina I, Brethour D, Schmitt-Ulms G, Nimmanon T, Ziliotto S, Kille P, Hogstrand C
Citation:
Biochem J. 2016 Jun 7. pii: BCJ20160388. [Epub ahead of print]
Epub:
Yes
Abstract:
There is growing evidence that zinc and its transporters are involved in cell migration during development and in cancer. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taylor KM, Muraina I, Brethour D, Schmitt-Ulms G, Nimmanon T, Ziliotto S, Kille P, Hogstrand C. Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration. Biochem J. 2016 Jun 7. pii: BCJ20160388. [Epub ahead of print].

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