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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy
Citation:
Mol Ther. 2016 Jul 12. doi: 10.1038/mt.2016.145. [Epub ahead of print] Epub:
Yes Abstract:
Loss of Survival Motor Neuron-1 (SMN1) causes Spinal Muscular Atrophy (SMA), a devastating neurodegenerative disease. SMN2 is a... Delivery Method:
Endo-Porter (cultures), icv (mice) Organism or Cell Type:
iPS-derived SMA motor neurons, mice Citation Extract: Osman EY, Washington CW 3rd, Kaifer KA, Mazzasette C, Patitucci TN, Florea KM, Simon ME, Ko CP, Ebert AD, Lorson CL. Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. Mol Ther. 2016 Jul 12. doi: 10.1038/mt.2016.145. [Epub ahead of print]. |
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
Citation:
Nat Genet. 2016 Jul 11. doi: 10.1038/ng.3607. [Epub ahead of print] Epub:
Yes Abstract:
Hematologic measures such as hematocrit and white blood cell (WBC) count are heritable and clinically relevant. We analyzed... Organism or Cell Type:
zebrafish Citation Extract: Pankratz N, Schick UM, Zhou Y, Zhou W, Ahluwalia TS, Allende ML, Auer PL, Bork-Jensen J, Brody JA, Chen MH, Clavo V, Eicher JD, Grarup N, Hagedorn EJ, Hu B, Hunker K, Johnson AD, Leusink M, Lu Y, Lyytikäinen LP, Manichaikul A, Marioni RE, Nalls MA, Pazoki R, Smith AV, van Rooij FJ, Yang ML, Zhang X, Zhang Y, Asselbergs FW, Boerwinkle E, Borecki IB, Bottinger EP, Cushman M, de Bakker PI, Deary IJ, Dong L, Feitosa MF, Floyd JS, Franceschini N, Franco OH, Garcia ME, Grove ML, Gudnason V, Hansen T, Harris TB, Hofman A, Jackson RD, Jia J, Kähönen M, Launer LJ, Lehtimäki T, Liewald DC, Linneberg A, Liu Y, Loos RJ, <authors hidden: database constraint> Thuesen BH, Tracy RP, Uitterlinden AG, Wang J, Wang J, Dehghan A, Huo Y, Cupples LA, Wilson JG, Proia RL, Zon LI, O'Donnell CJ, Reiner AP, Ganesh SK. Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits. Nat Genet. 2016 Jul 11. doi: 10.1038/ng.3607. [Epub ahead of print]. |
Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells
Citation:
Cells, 2016;5(3):31. doi:10.3390/cells5030031 Epub:
Not Epub Abstract:
Progeroid laminopathies, including Hutchinson-Gilford Progeria Syndrome (HGPS, OMIM #176670), are premature and accelerated... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human dermal fibroblasts Citation Extract: Harhouri K, Navarro C, Baquerre C, Da Silva N, Bartoli C, Casey F, Mawuse GK, Doubaj Y, Lévy N, De Sandre-Giovannoli A. Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells. Cells, 2016;5(3):31. doi:10.3390/cells5030031. |
The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis
Citation:
Biochem Biophys Res Commun. 2016 Jul 7. pii: S0006-291X(16)31136-6. doi: 10.1016/j.bbrc.2016.07.021. [Epub ahead of print] Epub:
Yes Abstract:
Alternative splicing is a major mechanism regulating pattern of gene expression through the production of multiple mRNAs from a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Lee SH, Lee HK, Kim C, Kim YK, Ismail T, Jeong Y, Park K, Park JW, Kwon OS, Kang BS, Lee DS, Park MJ, Park DS, Lee HS. The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis. Biochem Biophys Res Commun. 2016 Jul 7. pii: S0006-291X(16)31136-6. doi: 10.1016/j.bbrc.2016.07.021. [Epub ahead of print]. |
Expression and knockdown of zebrafish folliculin suggests requirement for embryonic brain morphogenesis
Citation:
BMC Dev Biol. 2016 Jul 8;16(1):23 Epub:
Not Epub Abstract:
BACKGROUND: Birt-Hogg-Dubé syndrome (BHD) is a dominantly inherited familial cancer syndrome characterised by the development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kenyon EJ, Luijten MN, Gill H, Li N, Rawlings M, Bull JC, Hadzhiev Y, van Steensel MA, Maher E, Mueller F. Expression and knockdown of zebrafish folliculin suggests requirement for embryonic brain morphogenesis. BMC Dev Biol. 2016 Jul 8;16(1):23. |
Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish
Citation:
J Endocrinol. 2016 Jul;230(1):125-42. doi: 10.1530/JOE-15-0376 Epub:
Not Epub Abstract:
Glucocorticoids (GCs) in utero influence embryonic development with consequent programmed effects on adult physiology and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilson KS, Tucker CS, Al-Dujaili EA, Holmes MC, Hadoke PW, Kenyon CJ, Denvir MA. Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish. J Endocrinol. 2016 Jul;230(1):125-42. doi: 10.1530/JOE-15-0376. |
Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia
Citation:
Am J Hum Genet. 2016;99(1):174-87 doi:10.1016/j.ajhg.2016.05.028 Epub:
Not Epub Abstract:
Autosomal-dominant tubulo-interstitial kidney disease (ADTKD) encompasses a group of disorders characterized by renal tubular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bolar NA, Golzio C, Živná M, Hayot G, Van Hemelrijk C, Schepers D, Vandeweyer G, Hoischen A, Huyghe JR, Raes A, Matthys E, Sys E, Azou M, Gubler M-C, Praet M, Van Camp G, McFadden K, Pediaditakis I, Přistoupilová A, Hodaňová K, Vyleťal P, Hartmannová H, Stránecký V, Hůlková H, Barešová V, Jedličková I, Sovová J, Hnízda A, Kidd K, Bleyer AJ, Spong RS, Vande Walle J, Mortier G, Brunner H, Van Laer L, Kmoch S, Katsanis N, Loeys BL. Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia. Am J Hum Genet. 2016;99(1):174-87 doi:10.1016/j.ajhg.2016.05.028. |
Wars2 is a determinant of angiogenesis
Citation:
Nat Comm. 2016;7:12061. doi:10.1038/ncomms12061 Epub:
Not Epub Abstract:
Coronary flow (CF) measured ex vivo is largely determined by capillary density that reflects angiogenic vessel formation in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang M, Sips P, Khin E, Rotival M, Sun X, Ahmed R, Widjaja AA, Schafer S, Yusoff P, Choksi PK, Ko NSJ, Singh MK, Epstein D, Guan Y, Houštěk J, Mracek T, Nuskova H, Mikell B, Tan J, Pesce F, Kolar F, Bottolo L, Mancini M, Hubner N, Pravenec M, Petretto E, MacRae C, Cook SA. Wars2 is a determinant of angiogenesis. Nat Comm. 2016;7:12061. doi:10.1038/ncomms12061. |
Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation
Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.036 Epub:
Yes Abstract:
During metazoan development, the temporal pattern of morphogen signaling is critical for organizing cell fates in space and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sako K, Pradhan SJ, Barone V, Ingles-Prieto Á, Müller P, Ruprecht V, Čapek D, Galande S, Janovjak H, Heisenberg C-P. Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.036. |
Dpp/BMP2-4 Mediates Signaling from the D-Quadrant Organizer in a Spiralian Embryo
Citation:
Curr Biol. 2016;[Epub ahead of print] doi:10.1016/j.cub.2016.05.059 Epub:
Not Epub Abstract:
In some animal groups, the secondary embryonic axis is patterned by a small group of cells, often called an organizer, that... Delivery Method:
microinjection Organism or Cell Type:
Ilyanassa (marine snail) Citation Extract: Lambert JD, Johnson AB, Hudson CN, Chan A. Dpp/BMP2-4 Mediates Signaling from the D-Quadrant Organizer in a Spiralian Embryo. Curr Biol. 2016;[Epub ahead of print] doi:10.1016/j.cub.2016.05.059. |