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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure

Authors:
Tolosa EJ, Fernández-Zapico ME, Battiato NL, Rovasio RA
Citation:
Eur J Cell Biol. 2016 Feb 20. pii: S0171-9335(16)30006-1. doi: 10.1016/j.ejcb.2016.02.003. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Our aim was to understand the involvement of Sonic hedgehog (Shh) morphogen in the oriented distribution of neural crest cells...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Tolosa EJ, Fernández-Zapico ME, Battiato NL, Rovasio RA. Sonic hedgehog is a chemotactic neural crest cell guide that is perturbed by ethanol exposure. Eur J Cell Biol. 2016 Feb 20. pii: S0171-9335(16)30006-1. doi: 10.1016/j.ejcb.2016.02.003. [Epub ahead of print].

Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation

Authors:
Chen C, Jin J, Lee GA, Silva E, Donoghue M
Citation:
Biol Open. 2016 Mar 9. pii: bio.015404. doi: 10.1242/bio.015404. [Epub ahead of print]
Epub:
Yes
Abstract:
A well-functioning brain requires production of the correct number and types of cells during development; cascades of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen C, Jin J, Lee GA, Silva E, Donoghue M. Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation. Biol Open. 2016 Mar 9. pii: bio.015404. doi: 10.1242/bio.015404. [Epub ahead of print].

vox homeobox gene: a novel regulator of midbrain-hindbrain boundary development in medaka fish?

Authors:
Fabian P, Pantzartzi CN, Kozmikova I, Kozmik Z
Citation:
Dev Genes Evol. 2016 Mar 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The midbrain-hindbrain boundary (MHB) is one of the key organizing centers of the vertebrate central nervous system (CNS). Its...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Fabian P, Pantzartzi CN, Kozmikova I, Kozmik Z. vox homeobox gene: a novel regulator of midbrain-hindbrain boundary development in medaka fish?. Dev Genes Evol. 2016 Mar 10. [Epub ahead of print].

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis

Authors:
Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG
Citation:
Sci Rep. 2016;6:23049. doi:10.1038/srep23049
Epub:
Not Epub
Abstract:
Noggin4 is a Noggin family secreted protein whose molecular and physiological functions remain unknown. In this study, we...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG. Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis. Sci Rep. 2016;6:23049. doi:10.1038/srep23049.

Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo

Authors:
Becerra S, Montes M, Hernández-Munain C, Suñé C
Citation:
RNA. 2015 Mar;21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20
Epub:
Not Epub
Abstract:
The first stable complex formed during the assembly of spliceosomes onto pre-mRNA substrates in mammals includes U1 snRNP,...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293T
Citation Extract:
Becerra S, Montes M, Hernández-Munain C, Suñé C. Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo. RNA. 2015 Mar;21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20.

Primary intestinal and vertebral chordomas in laboratory zebrafish (Danio rerio)

Authors:
Cooper TK, Murray KN, Spagnoli S, Spitsbergen JM
Citation:
Vet Pathol. 2015 Mar;52(2):388-92. doi: 10.1177/0300985814537531. Epub 2014 Jun 9
Epub:
Not Epub
Abstract:
Chordomas are uncommon neoplasms arising from notochord remnants, most commonly occurring in the axial skeleton. Extraskeletal...
Organism or Cell Type:
zebrafish
Citation Extract:
Cooper TK, Murray KN, Spagnoli S, Spitsbergen JM. Primary intestinal and vertebral chordomas in laboratory zebrafish (Danio rerio). Vet Pathol. 2015 Mar;52(2):388-92. doi: 10.1177/0300985814537531. Epub 2014 Jun 9.

The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle

Authors:
Lo HP, Nixon SJ, Hall TE, Cowling BS, Ferguson C, Morgan GP, Schieber NL, Fernandez-Rojo MA, Bastiani M, Floetenmeyer M, Martel N, Laporte J, Pilch PF, Parton RG
Citation:
J Cell Biol. 2015 Aug 31;210(5):833-49. doi: 10.1083/jcb.201501046
Epub:
Not Epub
Abstract:
Dysfunction of caveolae is involved in human muscle disease, although the underlying molecular mechanisms remain unclear. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lo HP, Nixon SJ, Hall TE, Cowling BS, Ferguson C, Morgan GP, Schieber NL, Fernandez-Rojo MA, Bastiani M, Floetenmeyer M, Martel N, Laporte J, Pilch PF, Parton RG. The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. J Cell Biol. 2015 Aug 31;210(5):833-49. doi: 10.1083/jcb.201501046.

Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium

Authors:
Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha M, Kim PG, Do EK, Kim JH, Schlaeger TM, Zon LI, Bigas A, Burns CE, Daley GQ
Citation:
Blood. 2015 Feb 26;125(9):1418-26. doi: 10.1182/blood-2014-04-568170. Epub 2015 Jan 13
Epub:
Not Epub
Abstract:
Hematopoietic and vascular development share many common features, including cell surface markers and sites of origin. Recent...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha M, Kim PG, Do EK, Kim JH, Schlaeger TM, Zon LI, Bigas A, Burns CE, Daley GQ. Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood. 2015 Feb 26;125(9):1418-26. doi: 10.1182/blood-2014-04-568170. Epub 2015 Jan 13.

Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia

Authors:
Wan Y, Zhang Q, Zhang Z, Song B, Wang X, Zhang Y, Jia Q, Cheng T, Zhu X, Leung AY, Yuan W, Jia H, Fang X
Citation:
BMC Med Genomics. 2016 Mar 9;9(1):13. doi: 10.1186/s12920-016-0174-9
Epub:
Not Epub
Abstract:
BACKGROUND: Diamond-Blackfan anemia (DBA) was the first ribosomopathy associated with mutations in ribosome protein (RP) genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wan Y, Zhang Q, Zhang Z, Song B, Wang X, Zhang Y, Jia Q, Cheng T, Zhu X, Leung AY, Yuan W, Jia H, Fang X. Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia. BMC Med Genomics. 2016 Mar 9;9(1):13. doi: 10.1186/s12920-016-0174-9.

Hexose enhances oligonucleotide delivery and exon skipping in dystrophin-deficient mdx mice

Authors:
Han G, Gu B, Cao L, Gao X, Wang Q, Seow Y, Zhang N, Wood MJA, Yin HF
Citation:
Nat Comm. 2016;7:10981. doi:10.1038/ncomms10981
Epub:
Not Epub
Abstract:
Carbohydrate-based infusion solutions are widely used in the clinic. Here we show that co-administration of phosphorodiamidate...
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Han G, Gu B, Cao L, Gao X, Wang Q, Seow Y, Zhang N, Wood MJA, Yin HF. Hexose enhances oligonucleotide delivery and exon skipping in dystrophin-deficient mdx mice. Nat Comm. 2016;7:10981. doi:10.1038/ncomms10981.

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