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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

Endothelial cilia are essential for developmental vascular integrity in zebrafish

Authors:
Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11
Epub:
Not Epub
Abstract:
The cilium is a signaling platform of the vertebrate cell. It has a critical role in polycystic kidney disease and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z. Endothelial cilia are essential for developmental vascular integrity in zebrafish. J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11.

A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS

Authors:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21
Epub:
Not Epub
Abstract:
FSGS is a clinical disorder characterized by focal scarring of the glomerular capillary tuft, podocyte injury, and nephrotic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP. A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21.

A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS

Authors:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21
Epub:
Not Epub
Abstract:
FSGS is a clinical disorder characterized by focal scarring of the glomerular capillary tuft, podocyte injury, and nephrotic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP. A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21.

Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth

Authors:
Chu C-W, Ossipova O, Ioannou A, Sokol SY
Citation:
Sci Rep. 2016;6:24104 doi:10.1038/srep24104
Epub:
Not Epub
Abstract:
PCP proteins maintain planar polarity in many epithelial tissues and have been implicated in cilia development in vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chu C-W, Ossipova O, Ioannou A, Sokol SY. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 doi:10.1038/srep24104.

Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning

Authors:
Perner B, Schnerwitzki D, Graf M, Englert C
Citation:
J Vis Exp. 2016;110:e53921. doi:10.3791/53921
Epub:
Not Epub
Abstract:
In order to understand organogenesis, the spatial and temporal alterations that occur during development of tissues need to be...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Perner B, Schnerwitzki D, Graf M, Englert C. Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning. J Vis Exp. 2016;110:e53921. doi:10.3791/53921.

Genetic Dissection of Dual Roles for the Transcription Factor six7 in Photoreceptor Development and Patterning in Zebrafish

Authors:
Sotolongo-Lopez M, Alvarez-Delfin K, Saade CJ, Vera DL, Fadool JM
Citation:
PLoS Genet. 2016;12(4):e1005968. doi:10.1371/journal.pgen.1005968
Epub:
Not Epub
Abstract:
The visual system of a particular species is highly adapted to convey detailed ecological and behavioral information essential...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sotolongo-Lopez M, Alvarez-Delfin K, Saade CJ, Vera DL, Fadool JM. Genetic Dissection of Dual Roles for the Transcription Factor six7 in Photoreceptor Development and Patterning in Zebrafish. PLoS Genet. 2016;12(4):e1005968. doi:10.1371/journal.pgen.1005968.

The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization

Authors:
Treat AC, Wheeler DS, Stolz DB, Tsang M, Friedman PA, Romero G
Citation:
PLoS ONE. 2016;11(4):e0153144. doi:10.1371/journal.pone.0153144
Epub:
Not Epub
Abstract:
Directional flow of the cerebrospinal fluid requires coordinated movement of the motile cilia of the ependymal epithelium that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Treat AC, Wheeler DS, Stolz DB, Tsang M, Friedman PA, Romero G. The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization. PLoS ONE. 2016;11(4):e0153144. doi:10.1371/journal.pone.0153144.

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma

Authors:
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie1 JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, David H. Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young YA, Zon LI
Citation:
Molec Cell. 2016:62(1)34-46. doi:10.1016/j.molcel.2016.03.013
Epub:
Not Epub
Abstract:
Studying cancer metabolism gives insight into tumorigenic survival mechanisms and susceptibilities. In melanoma, we identify...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie1 JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, David H. Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young YA, Zon LI. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molec Cell. 2016:62(1)34-46. doi:10.1016/j.molcel.2016.03.013.

Trim69 regulates zebrafish brain development by ap-1 pathway

Authors:
Han R, Wang R, Zhao Q, Han Y, Zong S, Miao S, Song W, Wang L
Citation:
Sci Rep. 2016 Apr 6;6:24034. doi: 10.1038/srep24034
Epub:
Not Epub
Abstract:
Proteins belonging to the TRIM family have been implicated in a variety of cellular processes such as apoptosis,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han R, Wang R, Zhao Q, Han Y, Zong S, Miao S, Song W, Wang L. Trim69 regulates zebrafish brain development by ap-1 pathway. Sci Rep. 2016 Apr 6;6:24034. doi: 10.1038/srep24034.

Characterization of primary cilia during the differentiation of retinal ganglion cells in the zebrafish

Authors:
Lepanto P, Davison C, Casanova G, Badano JL, Zolessi FR
Citation:
Neural Dev. 2016;11(10) doi:10.1186/s13064-016-0064-z
Epub:
Not Epub
Abstract:
Background: Retinal ganglion cell (RGC) differentiation in vivo is a highly stereotyped process, likely resulting from the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lepanto P, Davison C, Casanova G, Badano JL, Zolessi FR. Characterization of primary cilia during the differentiation of retinal ganglion cells in the zebrafish. Neural Dev. 2016;11(10) doi:10.1186/s13064-016-0064-z.

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