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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus

Authors:
Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C
Citation:
Development. 2015 Oct 1;142(19):3416-28. doi: 10.1242/dev.121871
Epub:
Not Epub
Abstract:
V1 interneurons are inhibitory neurons that play an essential role in vertebrate locomotion. The molecular mechanisms...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C. Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development. 2015 Oct 1;142(19):3416-28. doi: 10.1242/dev.121871.

Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2

Authors:
Butler MT, Wallingford JB
Citation:
Development. 2015 Oct 1;142(19):3429-39. doi: 10.1242/dev.121384. Epub 2015 Aug 20
Epub:
Not Epub
Abstract:
Planar cell polarity (PCP) is a ubiquitous property of animal tissues and is essential for morphogenesis and homeostasis. In...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Butler MT, Wallingford JB. Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2. Development. 2015 Oct 1;142(19):3429-39. doi: 10.1242/dev.121384. Epub 2015 Aug 20.

Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation

Authors:
Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW
Citation:
Genes Dev. 2015 Oct 1;29(19):2054-66. doi: 10.1101/gad.267245.115
Epub:
Not Epub
Abstract:
Alternative splicing is prevalent among genes encoding signaling molecules; however, the functional consequence of differential...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: Jurkat T cells
Citation Extract:
Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015 Oct 1;29(19):2054-66. doi: 10.1101/gad.267245.115.

Endothelial cilia are essential for developmental vascular integrity in zebrafish

Authors:
Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11
Epub:
Not Epub
Abstract:
The cilium is a signaling platform of the vertebrate cell. It has a critical role in polycystic kidney disease and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z. Endothelial cilia are essential for developmental vascular integrity in zebrafish. J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11.

A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS

Authors:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21
Epub:
Not Epub
Abstract:
FSGS is a clinical disorder characterized by focal scarring of the glomerular capillary tuft, podocyte injury, and nephrotic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP. A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21.

A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS

Authors:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP
Citation:
J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21
Epub:
Not Epub
Abstract:
FSGS is a clinical disorder characterized by focal scarring of the glomerular capillary tuft, podocyte injury, and nephrotic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hall G, Gbadegesin RA, Lavin P, Wu G, Liu Y, Oh EC, Wang L, Spurney RF, Eckel J, Lindsey T, Homstad A, Malone AF, Phelan PJ, Shaw A, Howell DN, Conlon PJ, Katsanis N, Winn MP. A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. J Am Soc Nephrol. 2015 Apr;26(4):831-43. doi: 10.1681/ASN.2013101053. Epub 2014 Aug 21.

Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth

Authors:
Chu C-W, Ossipova O, Ioannou A, Sokol SY
Citation:
Sci Rep. 2016;6:24104 doi:10.1038/srep24104
Epub:
Not Epub
Abstract:
PCP proteins maintain planar polarity in many epithelial tissues and have been implicated in cilia development in vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chu C-W, Ossipova O, Ioannou A, Sokol SY. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 doi:10.1038/srep24104.

Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning

Authors:
Perner B, Schnerwitzki D, Graf M, Englert C
Citation:
J Vis Exp. 2016;110:e53921. doi:10.3791/53921
Epub:
Not Epub
Abstract:
In order to understand organogenesis, the spatial and temporal alterations that occur during development of tissues need to be...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Perner B, Schnerwitzki D, Graf M, Englert C. Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning. J Vis Exp. 2016;110:e53921. doi:10.3791/53921.

Genetic Dissection of Dual Roles for the Transcription Factor six7 in Photoreceptor Development and Patterning in Zebrafish

Authors:
Sotolongo-Lopez M, Alvarez-Delfin K, Saade CJ, Vera DL, Fadool JM
Citation:
PLoS Genet. 2016;12(4):e1005968. doi:10.1371/journal.pgen.1005968
Epub:
Not Epub
Abstract:
The visual system of a particular species is highly adapted to convey detailed ecological and behavioral information essential...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sotolongo-Lopez M, Alvarez-Delfin K, Saade CJ, Vera DL, Fadool JM. Genetic Dissection of Dual Roles for the Transcription Factor six7 in Photoreceptor Development and Patterning in Zebrafish. PLoS Genet. 2016;12(4):e1005968. doi:10.1371/journal.pgen.1005968.

The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization

Authors:
Treat AC, Wheeler DS, Stolz DB, Tsang M, Friedman PA, Romero G
Citation:
PLoS ONE. 2016;11(4):e0153144. doi:10.1371/journal.pone.0153144
Epub:
Not Epub
Abstract:
Directional flow of the cerebrospinal fluid requires coordinated movement of the motile cilia of the ependymal epithelium that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Treat AC, Wheeler DS, Stolz DB, Tsang M, Friedman PA, Romero G. The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization. PLoS ONE. 2016;11(4):e0153144. doi:10.1371/journal.pone.0153144.

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