You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Enhanced angiogenesis, hypoxia and neutrophil recruitment during Myc-induced liver tumorigenesis in zebrafish

Authors:
Zhao Y, Huang X, Ding TW, Gong Z
Citation:
Sci Rep. 2016 Aug 23;6:31952. doi: 10.1038/srep31952
Epub:
Yes
Abstract:
Angiogenesis, hypoxia and immune cells are important components in tumor microenvironment affecting tumor growth. Here we...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Huang X, Ding TW, Gong Z. Enhanced angiogenesis, hypoxia and neutrophil recruitment during Myc-induced liver tumorigenesis in zebrafish. Sci Rep. 2016 Aug 23;6:31952. doi: 10.1038/srep31952.

A novel developmental role for dopaminergic signaling to specify hypothalamic neurotransmitter identity

Authors:
Chen YC, Semenova S, Rozov S, Sundvik M, Bonkowsky JL, Panula P
Citation:
J Biol Chem. 2016 Aug 18. pii: jbc.M115.697466. [Epub ahead of print]
Epub:
Yes
Abstract:
Hypothalamic neurons expressing histamine and orexin/ hypocretin (hcrt) are necessary for normal regulation of wakefulness. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YC, Semenova S, Rozov S, Sundvik M, Bonkowsky JL, Panula P. A novel developmental role for dopaminergic signaling to specify hypothalamic neurotransmitter identity. J Biol Chem. 2016 Aug 18. pii: jbc.M115.697466. [Epub ahead of print].

Quantitative Microinjection of Morpholino Antisense Oligonucleotides into Mouse Oocytes to Examine Gene Function in Meiosis-I

Authors:
Nakagawa S, FitzHarris G
Citation:
Methods Mol Biol. 2016;1457:217-30. doi: 10.1007/978-1-4939-3795-0_16
Epub:
Not Epub
Abstract:
Specific protein depletion is a powerful approach for assessing individual gene function in cellular processes, and has been...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Nakagawa S, FitzHarris G. Quantitative Microinjection of Morpholino Antisense Oligonucleotides into Mouse Oocytes to Examine Gene Function in Meiosis-I. Methods Mol Biol. 2016;1457:217-30. doi: 10.1007/978-1-4939-3795-0_16.

Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates

Authors:
Carver MP, Charleston JS, Shanks C, Zhang JB, Mense M, Sharma A, Kaur H, Sazani P
Citation:
J Neuromuscul Dis. 2016 Aug 30;3(3):381-393.
Epub:
Not Epub
Abstract:
Background: Phosphorodiamidate morpholino oligomers (PMOs) are a class of exon skipping drugs including eteplirsen, which has...
Delivery Method:
i.v. injection
Organism or Cell Type:
nonhuman primates
Citation Extract:
Carver MP, Charleston JS, Shanks C, Zhang JB, Mense M, Sharma A, Kaur H, Sazani P. Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates. J Neuromuscul Dis. 2016 Aug 30;3(3):381-393..

Physical association between a novel plasma-membrane structure and centrosome orients cell division

Authors:
Negishi T, Miyazaki N, Murata K, Yasuo H, Ueno N
Citation:
Elife. 2016 Aug 9;5. pii: e16550. doi: 10.7554/eLife.16550
Epub:
Not Epub
Abstract:
In the last mitotic division of the epidermal lineage in the ascidian embryo, the cells divide stereotypically along the...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Negishi T, Miyazaki N, Murata K, Yasuo H, Ueno N. Physical association between a novel plasma-membrane structure and centrosome orients cell division. Elife. 2016 Aug 9;5. pii: e16550. doi: 10.7554/eLife.16550.

HDAC1 negatively regulates Bdnf and Pvalb required for parvalbumin interneuron maturation in an experience-dependent manner

Authors:
Koh DX, Sng JC
Citation:
J Neurochem. 2016 Aug 17. doi: 10.1111/jnc.13773. [Epub ahead of print]
Epub:
Yes
Abstract:
During early postnatal development, neuronal circuits are sculpted by sensory experience provided by the external environment....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Koh DX, Sng JC. HDAC1 negatively regulates Bdnf and Pvalb required for parvalbumin interneuron maturation in an experience-dependent manner. J Neurochem. 2016 Aug 17. doi: 10.1111/jnc.13773. [Epub ahead of print].

Singapore grouper iridovirus protein VP088 is essential for viral infectivity

Authors:
Yuan Y, Wang Y, Liu Q, Zhu F, Hong Y
Citation:
Sci Rep. 2016 Aug 8;6:31170. doi: 10.1038/srep31170
Epub:
Not Epub
Abstract:
Viral infection is a great challenge in healthcare and agriculture. The Singapore grouper iridovirus (SGIV) is highly...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Oryzias latipes (Medaka) haploid ES cell line HX1
Citation Extract:
Yuan Y, Wang Y, Liu Q, Zhu F, Hong Y. Singapore grouper iridovirus protein VP088 is essential for viral infectivity. Sci Rep. 2016 Aug 8;6:31170. doi: 10.1038/srep31170.

Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo

Authors:
Levitte S, Adams KN, Berg RD, Cosma CL, Urdahl KB, Ramakrishnan L
Citation:
Cell Host Microbe. 2016 Aug 10;20(2):250-8. doi: 10.1016/j.chom.2016.07.007
Epub:
Not Epub
Abstract:
The blockade of phagolysosomal fusion is considered a critical mycobacterial strategy to survive in macrophages. However,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Levitte S, Adams KN, Berg RD, Cosma CL, Urdahl KB, Ramakrishnan L. Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo. Cell Host Microbe. 2016 Aug 10;20(2):250-8. doi: 10.1016/j.chom.2016.07.007.

Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis

Authors:
Bhuiyan MS, Ellett F, Murray GL, Kostoulias X, Cerqueira GM, Schulze KE, Mahamad Maifiah MH, Li J, Creek DJ, Lieschke GJ, Peleg AY
Citation:
Proc Natl Acad Sci U S A. 2016 Aug 9. pii: 201523116. [Epub ahead of print]
Epub:
Yes
Abstract:
Innate cellular immune responses are a critical first-line defense against invading bacterial pathogens. Leukocyte migration...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhuiyan MS, Ellett F, Murray GL, Kostoulias X, Cerqueira GM, Schulze KE, Mahamad Maifiah MH, Li J, Creek DJ, Lieschke GJ, Peleg AY. Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis. Proc Natl Acad Sci U S A. 2016 Aug 9. pii: 201523116. [Epub ahead of print].

Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome

Authors:
Lindstrand A, Frangakis S, Carvalho CM, Richardson EB, McFadden KA, Willer JR, Pehlivan D, Liu P, Pediaditakis IL, Sabo A, Lewis RA, Banin E, Lupski JR, Davis EE, Katsanis N
Citation:
Am J Hum Genet. 2016 Aug 4;99(2):318-36. doi: 10.1016/j.ajhg.2015.04.023
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a defining ciliopathy, notable for extensive allelic and genetic heterogeneity, almost all of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lindstrand A, Frangakis S, Carvalho CM, Richardson EB, McFadden KA, Willer JR, Pehlivan D, Liu P, Pediaditakis IL, Sabo A, Lewis RA, Banin E, Lupski JR, Davis EE, Katsanis N. Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl Syndrome. Am J Hum Genet. 2016 Aug 4;99(2):318-36. doi: 10.1016/j.ajhg.2015.04.023.

Pages