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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Analyzing In Vivo Cell Migration using Cell Transplantations and Time-lapse Imaging in Zebrafish Embryos

Authors:
Giger FA, Dumortier JG, David NB
Citation:
J Vis Exp. 2016;110):e53792. doi:10.3791/53792
Epub:
Not Epub
Abstract:
Cell migration is key to many physiological and pathological conditions, including cancer metastasis. The cellular and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giger FA, Dumortier JG, David NB. Analyzing In Vivo Cell Migration using Cell Transplantations and Time-lapse Imaging in Zebrafish Embryos. J Vis Exp. 2016;110):e53792. doi:10.3791/53792.

The LIM-homeodomain transcription factor Islet2a promotes angioblast migration

Authors:
Lamont RE, Wu CY, Ryu JR, Vu W, Davari P, Sobering RE, Kennedy RM, Munsie NM, Childs SJ
Citation:
Dev Biol. 2016 Apr 25. pii: S0012-1606(16)30237-8. doi: 10.1016/j.ydbio.2016.04.019. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Angioblasts of the developing vascular system require many signaling inputs to initiate their migration, proliferation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lamont RE, Wu CY, Ryu JR, Vu W, Davari P, Sobering RE, Kennedy RM, Munsie NM, Childs SJ. The LIM-homeodomain transcription factor Islet2a promotes angioblast migration. Dev Biol. 2016 Apr 25. pii: S0012-1606(16)30237-8. doi: 10.1016/j.ydbio.2016.04.019. [Epub ahead of print].

MicroRNA-140-5p impairs zebrafish embryonic bone development via targeting BMP-2

Authors:
Gan S, Huang Z, Liu N, Su R, Xie G, Zhong B, Zhang K, Wang S, Hu X, Zhang J, Xiang S
Citation:
FEBS Lett. 2016 Apr 30. doi: 10.1002/1873-3468.12190. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNA-140-5p (miRNA-140-5p) is important for embryonic bone development. In the present study, we found that miRNA-140-5p...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gan S, Huang Z, Liu N, Su R, Xie G, Zhong B, Zhang K, Wang S, Hu X, Zhang J, Xiang S. MicroRNA-140-5p impairs zebrafish embryonic bone development via targeting BMP-2. FEBS Lett. 2016 Apr 30. doi: 10.1002/1873-3468.12190. [Epub ahead of print].

Knockdown of zebrafish Nanog increases proliferation of primordial germ cells during early embryonic development

Authors:
Wang H, Liu Y, Ye D, Li J, Liu J, Deng F
Citation:
Dev Growth Differ. 2016 Apr 29. doi: 10.1111/dgd.12279. [Epub ahead of print]
Epub:
Yes
Abstract:
Nanog is a homeodomain transcription factor that plays a prominent role in maintaining the pluripotency and self-renewal...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang H, Liu Y, Ye D, Li J, Liu J, Deng F. Knockdown of zebrafish Nanog increases proliferation of primordial germ cells during early embryonic development. Dev Growth Differ. 2016 Apr 29. doi: 10.1111/dgd.12279. [Epub ahead of print].

Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish

Authors:
Ando K, Fukuhara S, Izumi N, Nakajima H, Fukui H, Kelsh RN, Mochizuki N
Citation:
Development. 2016 Apr 15;143(8):1328-39. doi: 10.1242/dev.132654. Epub 2016 Mar 7
Epub:
Not Epub
Abstract:
Mural cells (MCs) consisting of vascular smooth muscle cells and pericytes cover the endothelial cells (ECs) to regulate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ando K, Fukuhara S, Izumi N, Nakajima H, Fukui H, Kelsh RN, Mochizuki N. Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish. Development. 2016 Apr 15;143(8):1328-39. doi: 10.1242/dev.132654. Epub 2016 Mar 7.

Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

Authors:
Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M, German Mouse Clinic Consortium, de Angelis MH, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N
Citation:
Nat Comm. 2016;7:11317. doi:15.13155/ncomms11317
Epub:
Not Epub
Abstract:
Calcium signalling plays a critical role in the pathogenesis of heart failure. Here we describe a cardiac protein named...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eden M, Meder B, Völkers M, Poomvanicha M, Domes K, Branchereau M, Marck P, Will R, Bernt A, Rangrez A, Busch M, German Mouse Clinic Consortium, de Angelis MH, Heymes C, Rottbauer W, Most P, Hofmann F, Frey N. Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression. Nat Comm. 2016;7:11317. doi:15.13155/ncomms11317.

Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides

Authors:
Lin T-L, Chen T-H, Hsu Y-Y, Cheng Y-H, Juang B-T, Jong Y-J
Citation:
PLoS ONE. 2016;11(4): e0154723. doi:10.1371/journal.pone.0154723
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease caused by deficiency of the survival of motor...
Delivery Method:
injection, subcutaneous
Organism or Cell Type:
mice
Citation Extract:
Lin T-L, Chen T-H, Hsu Y-Y, Cheng Y-H, Juang B-T, Jong Y-J. Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides. PLoS ONE. 2016;11(4): e0154723. doi:10.1371/journal.pone.0154723.

Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA

Authors:
Costales MG, Rzuczek SG, Disney MD
Citation:
Bioorg Med Chem Lett. 2016 Apr 11. pii: S0960-894X(16)30386-9. doi: 10.1016/j.bmcl.2016.04.025. [Epub ahead of print]
Epub:
Yes
Abstract:
Potential RNA targets for chemical probes and therapeutic modalities are pervasive in the transcriptome. Oligonucleotide-based...
Delivery Method:
Vivo-Morpholino
Citation Extract:
Costales MG, Rzuczek SG, Disney MD. Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA. Bioorg Med Chem Lett. 2016 Apr 11. pii: S0960-894X(16)30386-9. doi: 10.1016/j.bmcl.2016.04.025. [Epub ahead of print].

The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion

Authors:
Wu N, Meng F, Invernizzi P, Bernuzzi F, Venter J, Standeford H, Onori P, Marzioni M, Alvaro D, Franchitto A, Gaudio E, Glaser S, Alpini G
Citation:
Hepatology. 2016 Apr 26. doi: 10.1002/hep.28622. [Epub ahead of print]
Epub:
Yes
Abstract:
The secretin/secretin receptor (SR) axis is upregulated by proliferating cholangiocytes during cholestasis. Secretin stimulates...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Wu N, Meng F, Invernizzi P, Bernuzzi F, Venter J, Standeford H, Onori P, Marzioni M, Alvaro D, Franchitto A, Gaudio E, Glaser S, Alpini G. The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion. Hepatology. 2016 Apr 26. doi: 10.1002/hep.28622. [Epub ahead of print].

Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae

Authors:
Reuter I, Knaup S, Romanos M, Lesch KP, Drepper C, Lillesaar C
Citation:
J Neural Transm (Vienna). 2016 Apr 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
First line pain relief medication during pregnancy relies nearly entirely on the over-the-counter analgesic acetaminophen,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reuter I, Knaup S, Romanos M, Lesch KP, Drepper C, Lillesaar C. Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae. J Neural Transm (Vienna). 2016 Apr 26. [Epub ahead of print].

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