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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Syndecan-4 modulates the proliferation of neural cells and the formation of CaP axons during zebrafish embryonic neurogenesis
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Citation:
Sci Rep. 2016;6:25300. doi:10.1038/srep25300 Epub:
Not Epub Abstract:
Syndecan-4 (Syn4), a single-pass transmembrane heparin sulphate proteoglycan (HSPG), plays significant role in the formation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Luo N, Li H, Xiang B, Qiao L, He J, Ji Y, Liu Y, Siying Li S, Lu R, Li Y, Meng W, Wu Y, Xu H,Xianming Mo X. Syndecan-4 modulates the proliferation of neural cells and the formation of CaP axons during zebrafish embryonic neurogenesis. Sci Rep. 2016;6:25300. doi:10.1038/srep25300. |
Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin
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Citation:
PLoS One. 2016 May 3;11(5):e0153768. doi: 10.1371/journal.pone.0153768. eCollection 2016 Epub:
Not Epub Abstract:
APOL1, a secreted high-density lipoprotein, is expressed in different human tissues. Genetic variants of APOL1 are described to... Delivery Method:
injection, Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Kotb AM, Simon O, Blumenthal A, Vogelgesang S, Dombrowski F, Amann K, Zimmermann U, Endlich K, Endlich N. Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin. PLoS One. 2016 May 3;11(5):e0153768. doi: 10.1371/journal.pone.0153768. eCollection 2016. |
Guide for Morpholino Users: Toward Therapeutics
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Citation:
J Drug Discov Develop and Deliv. 2016;3(2):1023 Epub:
Not Epub Abstract:
Morpholino oligos are uncharged molecules for blocking sites on RNA. They are specific, soluble, non-toxic, stable, and... Link:
Citation Extract: Moulton JD. Guide for Morpholino Users: Toward Therapeutics. J Drug Discov Develop and Deliv. 2016;3(2):1023. |
SUMOylation regulates growth factor independence 1 in transcriptional control and hematopoiesis
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Citation:
Mol Cell Biol. 2016;36:1438–1450. doi:10.1128/MCB.01001-15 Epub:
Not Epub Abstract:
Cell fate specification requires precise coordination of transcription factors and their regulators to achieve fidelity and... Organism or Cell Type:
zebrafish Citation Extract: Andrade D, Velinder M, Singer J, Maese L, Bareyan D, Nguyen H, Chandrasekharan MB, Lucente H, McClellan D, Jones D, Sharma S, Liu F, Engel ME. SUMOylation regulates growth factor independence 1 in transcriptional control and hematopoiesis. Mol Cell Biol. 2016;36:1438–1450. doi:10.1128/MCB.01001-15. |
Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes
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Citation:
BMC Genomics. 2016;17:318. doi:10.1186/s12864-016-2679-1 Epub:
Not Epub Abstract:
Background: Bardet-Biedl Syndrome (BBS) and Alström Syndrome are two pleiotropic ciliopathies with significant phenotypic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hostelley TL, Sukanya Lodh S, Zaghloul NA. Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes. BMC Genomics. 2016;17:318. doi:10.1186/s12864-016-2679-1. |
Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21)
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Citation:
Hum Mol Genet. 2016 Mar 22. pii: ddw096. [Epub ahead of print] Epub:
Yes Abstract:
Bardet Biedl syndrome (BBS) is a multisystem genetically heterogeneous ciliopathy that most commonly leads to obesity,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heon E, Kim G, Qin S, Garrison JE, Tavares E, Vincent A, Nuangchamnong N, Scott CA, Slusarski DC, Sheffield VC. Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21). Hum Mol Genet. 2016 Mar 22. pii: ddw096. [Epub ahead of print]. |
An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo
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Citation:
Development. 2016 Mar 7. pii: dev.128165. [Epub ahead of print] Epub:
Yes Abstract:
Anterior signaling centers are essential to specify and pattern the early anterior neuroectoderm (ANE) of many deuterostome... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Range RC, Wei Z. An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo. Development. 2016 Mar 7. pii: dev.128165. [Epub ahead of print]. |
An essential role for Grk2 in Hedgehog signalling downstream of Smoothened
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Citation:
EMBO Rep. 2016 Apr 4. pii: e201541532. [Epub ahead of print] Epub:
Not Epub Abstract:
The G-protein-coupled receptor kinase 2 (adrbk2/GRK2) has been implicated in vertebrate Hedgehog (Hh) signalling based on the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. EMBO Rep. 2016 Apr 4. pii: e201541532. [Epub ahead of print]. |
Different Modulatory Mechanisms of Renal FXYD12 for Na+-K+-ATPase between Two Closely Related Medakas upon Salinity Challenge
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Citation:
Int J Biol Sci. 2016;12(6):730-745. doi:10.7150/ijbs.15066 Epub:
Not Epub Abstract:
Upon salinity challenge, the Na+-K+-ATPase (NKA) of fish kidney plays a crucial role in maintaining ion and water balance.... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Yang W-K, Kang C-K, Hsu A-D, Lin C-H, Lee T-H. Different Modulatory Mechanisms of Renal FXYD12 for Na+-K+-ATPase between Two Closely Related Medakas upon Salinity Challenge. Int J Biol Sci. 2016;12(6):730-745. doi:10.7150/ijbs.15066. |
Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction
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Citation:
Skeletal Muscle. 2016;6:18. doi:10.1186/s13395-016-0089-3 Epub:
Not Epub Abstract:
Background: Remodeling of the extracellular matrix (ECM) regulates cell adhesion as well as signaling between cells and their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jenkins MH, Alrowaished SS, Goody MF, Crawford BD, Henry CA. Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction. Skeletal Muscle. 2016;6:18. doi:10.1186/s13395-016-0089-3. |