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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Rapid microinjection of fertilized eggs

Authors:
Cheers MS, Ettensohn CA
Citation:
Methods Cell Biol. 2004;74:287-310
Epub:
Not Epub
Abstract:
The chapter focuses on methods for using a picospritzer to inject large numbers of eggs that have been immobilized in open...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus and Lytechinus variegatus (sea urchin)
Citation Extract:
Cheers MS, Ettensohn CA. Rapid microinjection of fertilized eggs. Methods Cell Biol. 2004;74:287-310.

Performing functional studies of Xenopus laevis intermediate filament proteins through injection of macromolecules into early embryos

Authors:
Gervasi C, Szaro BG
Citation:
Methods Cell Biol. 2004;78:673-701
Epub:
Not Epub
Abstract:
The small size of Xenopus laevis embryos and their external development make it easy to study early developmental stages in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gervasi C, Szaro BG. Performing functional studies of Xenopus laevis intermediate filament proteins through injection of macromolecules into early embryos. Methods Cell Biol. 2004;78:673-701.

IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation

Authors:
Lu J, Liu KC, Schulz N, Karampelias C, Charbord J, Hilding A, Rautio L, Bertolino P, Östenson CG, Brismar K, Andersson O
Citation:
EMBO J. 2016 Aug 11. pii: e201592903. [Epub ahead of print]
Epub:
Yes
Abstract:
There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu J, Liu KC, Schulz N, Karampelias C, Charbord J, Hilding A, Rautio L, Bertolino P, Östenson CG, Brismar K, Andersson O. IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation. EMBO J. 2016 Aug 11. pii: e201592903. [Epub ahead of print].

ARGLU1 is a Glucocorticoid Receptor Coactivator and Splicing Modulator Important in Stress Hormone Signaling and Brain Development

Authors:
Magomedova L, Tiefenbach J, Zilberman E, Voisin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu CJ, Jeyasuria P, Bader GD, Hughes TR, Krause H, Blencowe BJ, Angers S, Cummins CL
Citation:
bioRxiv 2016. doi:10.1101/069161
Epub:
Not Epub
Abstract:
Prolonged exposure to glucocorticoid stress hormones precipitates mood and cognitive disorders. We identified arginine and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Magomedova L, Tiefenbach J, Zilberman E, Voisin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu CJ, Jeyasuria P, Bader GD, Hughes TR, Krause H, Blencowe BJ, Angers S, Cummins CL. ARGLU1 is a Glucocorticoid Receptor Coactivator and Splicing Modulator Important in Stress Hormone Signaling and Brain Development. bioRxiv 2016. doi:10.1101/069161.

Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling

Authors:
Paul S, Nandi B, Pattanayak S, Sinha S
Citation:
Tetrahedron Lett. 2012;53:4179-83. doi:10.1016/j.tetlet.2012.05.141
Epub:
Not Epub
Abstract:
Sonogashira coupling of 5-iodo uracil–morpholino monomer with different terminal alkynes has been achieved for first time in...
Citation Extract:
Paul S, Nandi B, Pattanayak S, Sinha S. Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling. Tetrahedron Lett. 2012;53:4179-83. doi:10.1016/j.tetlet.2012.05.141.

Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

Authors:
Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q
Citation:
Nat Commun. 2016 Aug 22;7:12603. doi: 10.1038/ncomms12603
Epub:
Not Epub
Abstract:
Microtubules function in TGF-β signalling by facilitating the cytoplasmic trafficking of internalized receptors and the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q. Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun. 2016 Aug 22;7:12603. doi: 10.1038/ncomms12603.

Rac Regulates Giardia lamblia Encystation by Coordinating Cyst Wall Protein Trafficking and Secretion

Authors:
Krtková J, Thomas EB, Alas GC, Schraner EM, Behjatnia HR, Hehl AB, Paredez AR
Citation:
MBio. 2016 Aug 23;7(4). pii: e01003-16. doi: 10.1128/mBio.01003-16
Epub:
Not Epub
Abstract:
Encystation of the common intestinal parasite Giardia lamblia involves the production, trafficking, and secretion of cyst wall...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Krtková J, Thomas EB, Alas GC, Schraner EM, Behjatnia HR, Hehl AB, Paredez AR. Rac Regulates Giardia lamblia Encystation by Coordinating Cyst Wall Protein Trafficking and Secretion. MBio. 2016 Aug 23;7(4). pii: e01003-16. doi: 10.1128/mBio.01003-16.

Identification and characterization of a progestin and adipoQ receptor (PAQR) structurally related to Paqr7 in the ovary of Cynoglossus semilaevis and its potential role in regulating oocyte maturation

Authors:
Shi B, Liu X, Thomas P, Pang Y, Xu Y, Li X, Li X
Citation:
Gen Comp Endocrinol. 2016 Aug 20. pii: S0016-6480(16)30246-5. doi: 10.1016/j.ygcen.2016.08.008. [Epub ahead of print]
Epub:
Yes
Abstract:
Membrane progestin receptors (mPRs) play an important role in the regulation of oocyte meiotic maturation in fish. However,...
Delivery Method:
microinjection
Organism or Cell Type:
Cynoglossus semilaevis (half-smooth tongue sole)
Citation Extract:
Shi B, Liu X, Thomas P, Pang Y, Xu Y, Li X, Li X. Identification and characterization of a progestin and adipoQ receptor (PAQR) structurally related to Paqr7 in the ovary of Cynoglossus semilaevis and its potential role in regulating oocyte maturation. Gen Comp Endocrinol. 2016 Aug 20. pii: S0016-6480(16)30246-5. doi: 10.1016/j.ygcen.2016.08.008. [Epub ahead of print].

Functional Diversification of the Four MARCKS Family Members in Zebrafish Neural Development

Authors:
Prieto D, Zolessi FR
Citation:
J Exp Zool B Mol Dev Evol. 2016 Aug 24. doi: 10.1002/jez.b.22691. [Epub ahead of print]
Epub:
Yes
Abstract:
Myristoylated alanin-rich C-kinase substrate (MARCKS) and MARCKS-like 1, each encoded by a different gene, comprise a very...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prieto D, Zolessi FR. Functional Diversification of the Four MARCKS Family Members in Zebrafish Neural Development. J Exp Zool B Mol Dev Evol. 2016 Aug 24. doi: 10.1002/jez.b.22691. [Epub ahead of print].

Aberrant expression of miR-153 is associated with overexpression of hypoxia-inducible factor-1α in refractory epilepsy

Authors:
Li Y, Huang C, Feng P, Jiang Y, Wang W, Zhou D, Chen L
Citation:
Sci Rep. 2016 Aug 24;6:32091. doi: 10.1038/srep32091
Epub:
Not Epub
Abstract:
Evidence suggest that overexpression of hypoxia-inducible factor-1α (HIF-1α) is linked to multidrug resistance of epilepsy....
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: rat astrocytes
Citation Extract:
Li Y, Huang C, Feng P, Jiang Y, Wang W, Zhou D, Chen L. Aberrant expression of miR-153 is associated with overexpression of hypoxia-inducible factor-1α in refractory epilepsy. Sci Rep. 2016 Aug 24;6:32091. doi: 10.1038/srep32091.

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